ISOXAZOLE DERIVATIVE AND ISOTHIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON 11(beta)-HYDROXYSTEROID DEHYDROGENASE TYPE I

ABSTRACT

Disclosed is a compound useful as an inhibitor of 11β-hydroxysteroid dehydrogenase type 1. 
     A compound represented by the formula: 
     
       
         
         
             
             
         
       
     
     a pharmaceutically acceptable salt or solvate thereof,
 
wherein
 
R 1  is a group of the formula: —C(═O)NR 4 R 5 ,
 
(wherein R 4  and R 5  are each independently, hydrogen, optionally substituted alkyl or the like) or
 
a group of the formula: —NR 6 C(═O)R 7 ,
 
(wherein R 6  and R 7  are each independently, hydrogen, optionally substituted alkyl or the like),
 
X and Y are each independently —O— or the like,
 
Z is a bond or the like,
 
R 2  is optionally substituted alkyl, optionally substituted alkenyl or the like,
 
R 3  is optionally substituted alkyl, optionally substituted alkenyl or the like.

FIELD OF THE INVENTION

This invention relates to a pharmaceutically useful compound with aninhibitory activity on 11β-hydroxysteroid dehydrogenase type 1,hereinafter referred to as 11β-HSD-1.

BACKGROUND ART

11β-HSD-1 is an enzyme that converts inactive steroids,11β-dehydrosteroid into its active steroids and is considered to beimportant in the basal metabolic rate in the living body (Non-patentDocument 1). Moreover, 11β-HSD-1 knockout mice have the resistance tohyperglycemia induced by obesity or stress (Non-patent Document 2). Inaddition, a similar phenomenon was observed in human on administrationof 11β-HSD-1 inhibitor, carbenoxolone (Non-patent Document 3). Thesefacts suggest that the 11β-HSD-1 inhibitors could be useful as drugs forthe treatment of insulin independent diabetes or obesity (Non-patentDocument 4).

The compounds having an isoxazole group have been described in PatentDocument 1 as a useful compound for the treatment of hypertension aswell as inflammation and the structures of them are limited to thatwithout substituent at 4-position on an isoxazole group, and nocompounds having the substituent on an isoxazole group such as thepresent compound have been described.

Patent Documents 2 to 4 disclose various compounds that have theinhibitory activity on 116-hydroxysteroid dehydrogenase type 1.

Patent Documents 2 and 3 mainly disclose the compounds that have aphenyl group, but do not disclose the compounds that have an isoxazolegroup described in the present invention.

Patent Document 4 does not disclose the compounds having an isoxazolegroup described in the present invention.

Patent Documents 5 and 6 mainly disclose the compounds that have aphenyl group, but do not disclose the compounds that have an isoxazolegroup described in the present invention.

Patent Document 7 does not disclose the compounds having an isoxazolegroup described in the present invention.

[Patent Document 1] U.S. Pat. No. 4,562,187

[Patent Document 2] WO04/056744 [Patent Document 3] WO04/056745 [PatentDocument 4] WO04/065351 [Patent Document 5] WO06/002361 [Patent Document6] WO06/012227 [Patent Document 7] WO05/108368

[Non-patent Document 1] Clin. Endocrinol, 1996, 44, 493[Non-patent Document 2] Proc. Nat. Acad. Sci. USA, 1997, 94, 14924[Non-patent Document 3] J. Clin. Endocrinol. Metab. 1995, 80, 3155

[Non-patent Document 4] Lancet, 1997, 349, 1210 DISCLOSURE OF INVENTIONProblems to be Solved by the Invention

The present invention provides useful compounds having an inhibitoryactivity on 11β-hydroxysteroid dehydrogenase type 1.

Means for Solving the Problem

The present invention provides;

(1) A compound represented by the formula (I):

a pharmaceutically acceptable salt or a solvate thereof,whereinR¹ is a group of the formula: —C(═O)NR⁴R⁵,

-   -   wherein R⁴ and R⁵ are each independently, hydrogen, optionally        substituted alkyl, optionally substituted alkenyl, optionally        substituted alkynyl, optionally substituted cycloalkyl,        optionally substituted cycloalkenyl, optionally substituted        aryl, optionally substituted heteroaryl or optionally        substituted heterocycle; or R⁴ and R⁵ taken together with the        adjacent nitrogen atom to which they are attached may form an        optionally substituted ring or        a group of the formula: —NR⁶C(═O)R⁷,    -   wherein R⁶ is hydrogen, optionally substituted alkyl, optionally        substituted alkenyl, optionally substituted alkynyl, optionally        substituted cycloalkyl, optionally substituted cycloalkenyl,        optionally substituted aryl, optionally substituted heteroaryl,        optionally substituted heterocycle, optionally substituted        aralkyl or a group of the formula:—C(═O)R⁸,    -   R⁷ and R⁸ are each independently, hydrogen, optionally        substituted alkyl, optionally substituted alkenyl, optionally        substituted alkynyl, optionally substituted cycloalkyl,        optionally substituted cycloalkenyl, optionally substituted        aryl, optionally substituted heteroaryl or optionally        substituted heterocycle; or R⁷ and R⁸ taken together with the        adjacent carbon atom to which they are attached may form an        optionally substituted ring,        X and Y are each independently, —O— or —S—,        Z is a bond, —O— or —S—,        R² is optionally substituted alkyl, optionally substituted        alkenyl, optionally substituted alkynyl, optionally substituted        cycloalkyl, optionally substituted cycloalkenyl, optionally        substituted aryl, optionally substituted heteroaryl, optionally        substituted heterocycle, optionally substituted acyl or        optionally substituted carbamoyl,        R³ is optionally substituted alkyl, optionally substituted        alkenyl, optionally substituted alkynyl, optionally substituted        cycloalkyl, optionally substituted cycloalkenyl, optionally        substituted aryl, optionally substituted heteroaryl, optionally        substituted heterocycle, optionally substituted acyl, optionally        substituted carbamoyl, optionally substituted thiocarbamoyl,        optionally substituted amino, optionally substituted sulfamoyl        or a group of the formula: —R⁹—C(R¹⁰R¹¹)—R¹²—R¹³,    -   R⁹ is —(CH₂)m-, wherein m is an integer of 0 to 3,    -   R¹⁰ and R¹¹ are each independently, hydrogen, optionally        substituted alkyl or halogen; or R¹⁰ and R¹¹ taken together with        the adjacent carbon atom to which they are attached may form an        optionally substituted ring,    -   R¹² is —(CH₂)n-, wherein n is an integer of 0 to 3,    -   R¹³ is hydrogen, hydroxy, carboxy, cyano, optionally substituted        alkyl, optionally substituted alkenyl, optionally substituted        alkynyl, optionally substituted cycloalkyl, optionally        substituted cycloalkenyl, optionally substituted aryl,        optionally substituted heteroaryl, optionally substituted        heterocycle, optionally substituted alkoxycarbonyl, optionally        substituted aralkylcarbonyl, optionally substituted carbamoyl,        optionally substituted thiocarbamoyl, optionally substituted        alkylsulfonyl, optionally substituted arylsulfonyl, optionally        substituted sulfamoyl, optionally substituted amino, optionally        substituted carbamoyloxy, optionally substituted alkoxy,        optionally substituted alkylthio,    -   a group of the formula: —C(═O)—NR¹⁴R¹⁵,        -   wherein R¹⁴ and R¹⁵ are each independently, hydrogen,            optionally substituted amino, optionally substituted alkyl,            optionally substituted alkenyl, optionally substituted            alkynyl, optionally substituted cycloalkyl, optionally            substituted cycloalkenyl, optionally substituted aryl,            optionally substituted heteroaryl, optionally substituted            heterocycle, optionally substituted alkylsulfonyl,            optionally substituted arylsulfonyl, optionally substituted            heteroarylsulfonyl or optionally substituted            heterocyclesulfonyl; or R¹⁴ and R¹⁵ taken together with the            adjacent nitrogen atom to which they are attached may form            an optionally substituted ring or    -   a group of the formula: —NR¹⁶R¹⁷,        -   wherein R¹⁶ and R¹⁷ are each independently, hydrogen,            carboxy, hydroxy, optionally substituted alkyl, optionally            substituted alkenyl, optionally substituted alkynyl,            optionally substituted cycloalkyl, optionally substituted            cycloalkenyl, optionally substituted aryl, optionally            substituted heteroaryl, optionally substituted heterocycle,            optionally substituted acyl, optionally substituted            carbamoyl, optionally substituted thiocarbamoyl, optionally            substituted alkylsulfonyl, optionally substituted            arylsulfonyl, optionally substituted alkyloxycarbonyl or            optionally substituted sulfamoyl; or R¹⁶ and R¹⁷ taken            together with the adjacent nitrogen atom to which they are            attached may form an optionally substituted ring,            provided that, when R² encompasses a cyclic group and Y is            —S—, then the compound is any one of compounds shown as            follows,

(2) The compound according to the above (1), a pharmaceuticallyacceptable salt or a solvate thereof, wherein the compound of theformula (I):

is a compound of the formula (II) represented below,

(3) The compound according to the above (2), a pharmaceuticallyacceptable salt or a solvate thereof, wherein R¹ is a group of theformula: —C(═O)NR⁴R⁵, wherein R⁴ and R⁵ have the same meaning as definedin the above (1), Y is —S— and z is 0,(4) The compound according to the above (1) or (2), a pharmaceuticallyacceptable salt or a solvate thereof, wherein R¹ is a group of theformula: —C(═O)NR⁴R⁵, wherein R⁴ and R⁵ have the same meaning as definedin the above (1),(5) The compound according to the above (3) or (4), a pharmaceuticallyacceptable salt or a solvate thereof, wherein either one of R⁴ and R⁵ isoptionally substituted cycloalkyl,(6) The compound according to the above (5), a pharmaceuticallyacceptable salt or a solvate thereof, wherein either one of R⁴ and R⁵ isoptionally substituted adamantly,(7) The compound according to the above (3) or (4), a pharmaceuticallyacceptable salt or a solvate thereof,wherein R¹ is a group of the formula (III):

(8) The compound according to any one of the above (1) to (3), apharmaceutically acceptable salt or a solvate thereof, wherein R² isoptionally substituted alkyl, optionally substituted cycloalkyl,optionally substituted aryl, optionally substituted heteroaryl oroptionally substituted heterocycle,(9) The compound according to the above (8), a pharmaceuticallyacceptable salt or a solvate thereof, wherein R² isoptionally substituted alkyl wherein the substituent of said optionallysubstituted alkyl does not encompass a cyclic group,optionally substituted alkenyl wherein the substituent of saidoptionally substituted alkenyl does not encompass a cyclic group,optionally substituted alkynyl wherein the substituent of saidoptionally substituted alkynyl does not encompass a cyclic group,optionally substituted acyl wherein the substituent of said optionallysubstituted acyl does not encompass a cyclic group oroptionally substituted carbamoyl wherein the substituent of saidoptionally substituted carbamoyl does not encompass a cyclic group,(10) The compound according to the above (9), a pharmaceuticallyacceptable salt or a solvate thereof, wherein R² is optionallysubstituted alkyl wherein the substituent of said optionally substitutedalkyl does not encompass a cyclic group,(11) The compound according to the above (10), a pharmaceuticallyacceptable salt or a solvate thereof, wherein R² is branched alkyl,(12) The compound according to any one of the above (1) to (3), apharmaceutically acceptable salt or a solvate thereof, wherein R³ is agroup of the formula: —R⁹—C(R¹⁰R¹¹)—R¹²—R¹³, wherein R⁹, R¹⁰, R¹¹, R¹²and R¹³ have the same meaning as defined in the above (1),(13) The compound according to the above (12), a pharmaceuticallyacceptable salt or a solvate thereof, wherein R⁹ is —CH₂—,(14) The compound according to the above (12) or (13), apharmaceutically acceptable salt or a solvate thereof, wherein R¹⁰ andR¹¹ are each independently, optionally substituted alkyl; orR¹⁰ and R¹¹ taken together with the adjacent carbon atom to which theyare attached may form an optionally substituted ring,(15) The compound according to any one of the above (12) to (14), apharmaceutically acceptable salt or a solvate thereof, wherein R¹² is—(CH₂)n- wherein n is an integer of 0 or 1,(16) The compound according to any one of the above (12) to (15), apharmaceutically acceptable salt or a solvate thereof, wherein R¹³ iscarboxy, cyano or heterocycle,(17) The compound according to any one of the above (12) to (15), apharmaceutically acceptable salt or a solvate thereof, wherein R¹³ is agroup of the formula: —C(═O)—NR¹⁴R¹⁵wherein R¹⁴ and R¹⁵ are each independently hydrogen, optionallysubstituted alkyl, optionally substituted aryl, optionally substitutedcycloalkyl, optionally substituted alkylsulfonyl, optionally substitutedarylsulfonyl, optionally substituted heteroarylsulfonyl, optionallysubstituted heterocyclesulfonyl or optionally substituted heterocycle;or R¹⁴ and R¹⁵ taken together with the adjacent nitrogen atom to whichthey are attached may form an optionally substituted ring,(18) The compound according to any one of the above (12) to (15), apharmaceutically acceptable salt or a solvate thereof, wherein R¹³ is agroup of the formula: —NR¹⁶R¹⁷, wherein R¹⁶ and R¹⁷ have the samemeaning as defined in the above (1),(19) The compound according to the above (18), a pharmaceuticallyacceptable salt or a solvate thereof, wherein R¹⁶ is a group of theformula: —C(═O)R′, wherein R′ is optionally substituted alkyl,optionally substituted alkenyl, optionally substituted cycloalkyl,optionally substituted aryl, optionally substituted amino or optionallysubstituted alkoxy,(20) The compound according to any one of the above (1) to (3), apharmaceutically acceptable salt or a solvate thereof, wherein X and/orZ is(are)-O—,(21) The compound according to any one of the above (1) to (3), apharmaceutically acceptable salt or a solvate thereof, wherein Y is —S—,(22) A pharmaceutical composition which comprises the compound accordingto any one of the above (1) to (21), a pharmaceutically acceptable saltor a solvate thereof,(23) The pharmaceutical composition according to the above (22) whichhas an inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1,(24) The pharmaceutical composition according to the above (22) or (23)for treating and/or preventing diabetes,(25) A method for treating and/or preventing diabetes, comprisingadministering the compound of any one of the above (1) to (21), apharmaceutically acceptable salt or a solvate thereof,(26) A use of the compound of any one of the above (1) to (21), apharmaceutically acceptable salt or a solvate thereof for themanufacture of a pharmaceutical composition for treating and/orpreventing diabetes.

EFFECT OF THE INVENTION

The compounds of the present invention possess an inhibitory activity on11β-hydroxysteroid dehydrogenase type 1 and the pharmaceuticalcompositions comprising them are very useful for a medicament,especially a medicament for treating and/or preventing hyperlipidemia,diabetes, obesity, arteriosclerosis, atherosclerosis, hyperglycemiaand/or syndrome X. Moreover, the compounds of the present inventionselectively inhibit 11β-hydroxysteroid dehydrogenase type 1. Thepreferable compounds in the present compounds have a high metabolicstability, a weak drug metabolizing enzyme induction, a weak drugmetabolizing enzyme inhibition or a high oral absorption, and they areespecially useful for a medicament. In addition, the present inventionincludes compounds having a low clearance and a long half-life periodfor exhibiting the drug activity.

BEST MODE FOR CARRYING OUT THE INVENTION

Terms used in the present specification are explained below. Each termhas the following meanings alone or together with other terms.

“Alkyl” means a C1 to C10 straight or branched alkyl group, for example,methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl,tert-butyl, n-pentyl, isopentyl, neopentyl, n-hexyl, isohexyl, n-heptyl,n-octyl, n-nonyl, n-decyl or the like. Preferred is a C1 to C6 alkyl ora C1 to C4 alkyl, for example, methyl, ethyl, n-propyl, isopropyl,n-butyl, isobutyl, sec-butyl, tert-butyl, n-pentyl, isopentyl,neopentyl, n-hexyl, isohexyl.

“Alkenyl” means a C2 to C8 straight or branched alkenyl group, whichincludes a group having one or more double bond(s) in the above “alkyl”.Exemplified is vinyl, 1-propenyl, 2-propenyl, 1-butenyl, 2-butenyl,3-butenyl, 1,3-butadienyl, 3-methyl-2-butenyl or the like.

“Alkynyl” means a C2 to C8 straight or branched alkynyl group, whichincludes a group having one or more triple bond(s) in the above “alkyl”.Exemplified is ethynyl, propynyl, butynyl or the like.

“Cycloalkyl” means a C3 to C15 saturated cyclic hydrocarbon group.Bridged cyclic hydrocarbon group is also included. Exemplified iscyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl,cyclooctyl or bridged cyclic hydrocarbon group, exemplified as follows.Preferred is cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, bridgedcyclic hydrocarbon group, exemplified as follows or the like.

“Cycloalkenyl” means a C3 to C15 cyclic unsaturated aliphatichydrocarbon group. Exemplified is cyclopropenyl, cyclobutenyl,cyclopentenyl, cyclohexenyl or cycloheptenyl. Preferred iscyclopropenyl, cyclobutenyl, cyclopentenyl or cyclohexenyl. Cycloalkenylincludes a bridged cyclic hydrocarbon group having unsaturated bond inthe ring. Exemplified is a group having one or two double bond(s) in theabove exemplified bridged cyclic hydrocarbon group.

“Aryl” means a monocyclic aromatic hydrocarbon group (e.g., phenyl) or afused aromatic hydrocarbon group (e.g., 1-naphthyl, 2-naphthyl,1-anthryl, 2-anthryl, 9-anthryl, 1-phenanthryl, 2-phenanthryl,3-phenanthryl, 4-phenanthryl, 9-phenanthryl etc.). Preferred is phenylor naphthyl (1-naphthyl, 2-naphthyl) or the like.

“Heteroaryl” means a monocyclic aromatic heterocyclic group or fusedaromatic heterocyclic group.

The monocyclic aromatic heterocyclic group means a group derived from 5to 8-membered aromatic ring which may contain 1 to 4 oxygen, sulfurand/or nitrogen atom(s) in the ring. The binding bond can be at anysubstitutable position.

The fused aromatic heterocyclic group means a group derived from 5 to8-membered aromatic ring which may contain 1 to 4 oxygen, sulfur and/ornitrogen atom(s) in the ring fused with one to four of 5 to 8-memberedaromatic carbocycle(s) or other 5 to 8-membered aromatic heterocycle(s).The binding bond can be at any substitutable position.

“Heteroaryl” includes, for example, furyl (e.g., furan-2-yl orfuran-3-yl), thienyl (e.g., thiophene-2-yl or thiophene-3-yl), pyrrolyl(e.g., pyrrole-1-yl, pyrrole-2-yl or pyrrole-3-yl), imidazolyl (e.g.,imidazole-1-yl, imidazole-2-yl or imidazole-4-yl), pyrazolyl (e.g.,pyrazole-1-yl, pyrazole-3-yl or pyrazole-4-yl), triazolyl (e.g.,1,2,4-triazole-1-yl, 1,2,4-triazole-3-yl or 1,2,4-triazole-4-yl),tetrazolyl (e.g., tetrazole-1-yl, tetrazole-2-yl or tetrazole-5-yl),oxazolyl (e.g., oxazole-2-yl, oxazole-4-yl or oxazole-5-yl), isoxazolyl(e.g., isoxazole-3-yl, isoxazole-4-yl or isoxazole-5-yl), thiazolyl(e.g., thiazole-2-yl, thiazole-4-yl or thiazole-5-yl), thiadiazolyl,isothiazolyl (e.g., isothiazole-3-yl, isothiazole-4-yl orisothiazole-5-yl), pyridyl (e.g., pyridine-2-yl, pyridine-3-yl orpyridine-4-yl), pyridazinyl (e.g., pyridazine-3-yl or pyridazine-4-yl),pyrimidinyl (e.g., pyrimidine-2-yl, pyrimidine-4-yl or pyrimidine-5-yl),furazanyl (e.g., furazan-3-yl), pyrazinyl (e.g., pyrazine-2-yl),oxadiazolyl (e.g., 1,3,4-oxadiazole-2-yl), benzofuryl (e.g.,benzo[b]furan-2-yl, benzo[b]furan-3-yl, benzo[b]furan-4-yl,benzo[b]furan-5-yl, benzo[b]furan-6-yl or benzo[b]furan-7-yl),benzothienyl (e.g., benzo[b]thiophene-2-yl, benzo[b]thiophene-3-yl,benzo[b]thiophene-4-yl, benzo[b]thiophene-5-yl, benzo[b]thiophene-6-ylor benzo[b]thiophene-7-yl), benzimidazolyl (e.g., benzimidazole-1-yl,benzimidazole-2-yl, benzimidazole-4-yl or benzimidazole-5-yl),dibenzofuryl, benzoxazolyl, quinoxalyl (e.g., quinoxaline-2-yl,quinoxaline-5-yl or quinoxaline-6-yl), cinnolyl (e.g., cinnoline-3-yl,cinnoline-4-yl, cinnoline-5-yl, cinnoline-6-yl, cinnoline-7-yl orcinnoline-8-yl), quinazolyl (e.g., quinazoline-2-yl, quinazoline-4-yl,quinazoline-5-yl, quinazoline-6-yl, quinazoline-7-yl orquinazoline-8-yl), quinolyl (e.g., quinoline-2-yl, quinoline-3-yl,quinoline-4-yl, quinoline-5-yl, quinoline-6-yl, quinoline-7-yl orquinoline-8-yl), phthalazinyl (e.g., phthalazine-1-yl, phthalazine-5-ylor phthalazine-6-yl), isoquinolyl (e.g., isoquinoline-1-yl,isoquinoline-3-yl, isoquinoline-4-yl, isoquinoline-5-yl,isoquinoline-6-yl, isoquinoline-7-yl or isoquinoline-8-yl), puryl,pteridinyl (e.g., pteridine-2-yl, pteridine-4-yl, pteridine-6-yl orpteridine-7-yl), carbazolyl, phenanthridinyl, acridinyl (e.g.,acridine-1-yl, acridine-2-yl, acridine-3-yl, acridine-4-yl oracridine-9-yl), indolyl (e.g., indole-1-yl, indole-2-yl, indole-3-yl,indole-4-yl, indole-5-yl, indole-6-yl or indole-7-yl), isoindolyl,phenazinyl (e.g., phenazine-1-yl or phenazine-2-yl), phenothiazinyl(e.g., phenothiazine-1-yl, phenothiazine-2-yl, phenothiazine-3-yl orphenothiazine-4-yl) or the like.

“Heterocycle” means a nonaromatic heterocycle group which may contain 1to 4 oxygen, sulfur and/or nitrogen atom(s) in the ring. The bindingbond can be at any substitutable position. Moreover, the nonaromaticheterocycle group can be bridged with a C1 to C4 alkyl chain or can befused with cycloalkane (preferred is 5 to 6-membered ring) or benzenering. Heterocycle can be saturated or unsaturated, as long as it isnonaromatic. Preferred is 5 to 8-membered ring. Exemplified is1-pyrrolinyl, 2-pyrrolinyl, 3-pyrrolinyl, 1-pyrrolidinyl,2-pyrrolidinyl, 3-pyrrolidinyl, 1-imidazolinyl, 2-imidazolinyl,4-imidazolinyl, 1-imidazolidinyl, 2-imidazolidinyl, 4-imidazolidinyl,1-pyrazolinyl, 3-pyrazolinyl, 4-pyrazolinyl, 1-pyrazolidinyl,3-pyrazolidinyl, 4-pyrazolidinyl, piperidino, 2-piperidinyl,3-piperidinyl, 4-piperidinyl, 1-piperazinyl, 2-piperazinyl,2-morpholinyl, 3-morpholinyl, morpholino, tetrahydropyranyl, or thefollowing groups.

The alkyl part of “alkoxy” and “alkylthio” is the same as the above“alkyl”.

“Aralkyl” means the above alkyl substituted with 1 to 3 of the abovearyl.

“Acyl” means formyl, optionally substituted alkylcarbonyl, optionallysubstituted alkenylcarbonyl, optionally substituted cycloalkylcarbonyl,optionally substituted cycloalkenylcarbonyl, optionally substitutedarylcarbonyl, optionally substituted heteroarylcarbonyl or optionallysubstituted heterocyclecarbonyl.

“Halogen” means F, Cl, Br or I. Preferred is F or Cl.

“A ring formed by taking together R⁴ and R⁵ with the adjacent nitrogenatom to which they are attached” means 3 to 15-membered nonaromatichetero ring which may contain 1 to 4 oxygen, sulfer, and/or nitrogenatom(s) besides the above nitrogen atom in the ring. The nonaromatichetero ring can be bridged with C1 to C4 alkyl chain and can be fusedwith cycloalkane (preferred is 5 to 6-membered ring) or benzene ring.The ring can be saturated or unsaturated, as long as it is nonaromatic.Preferred is 5 to 8-membered ring. For example, a group of the formula:—NR⁴R⁵ wherein R⁴ and R⁵ taken together with the adjacent nitrogen atomto which they are attached may form an optionally substituted ring areexemplified as follows. 1-Pyrrolinyl, 1-pyrrolidinyl, 1-imidazolinyl,1-imidazolidinyl, 1-pyrazolinyl, 1-pyrazolidinyl, piperidino, morpholinoand the following group are exemplified.

“A ring formed by taking together R⁷ and R⁸ with the adjacent carbonatom to which they are attached” means nonaromatic hetero ring which maycontain 1 to 4 oxygen, sulfer, and/or nitrogen atom(s) besides thenitrogen atom in the ring. The nonaromatic hetero ring can be fused withcycloalkane (preferred is 5 to 6-membered ring) or cycloalkene(preferred is 5 to 6-membered ring) and be bridged with C1 to C4 alkylchain or hetero atom. The ring can be saturated or unsaturated, as longas it is nonaromatic. For example, a group of the formula:—N(—C(═O)R⁷)(—C(═O)R⁸) wherein R⁷ and R⁸ taken together with theadjacent carbon atom to which they are attached may form an optionallysubstituted ring are exemplified as follows.

“A ring formed by taking together R¹⁰ and R¹¹ with the adjacent carbonatom to which they are attached” means 3 to 15-membered saturated orunsaturated hydrocarbon ring or 3 to 15-membered saturated orunsaturated hetero ring containing 1 to 4 oxygen, sulfer, and/ornitrogen atom(s) in said hydrocarbon ring. Preferred is nonaromaticring, for example, cyclopropane, cyclobutane, cyclopentane, cyclohexane,cycloheptane, cyclooctane, cyclopropene, cyclobutene, cyclopentene,cyclohexene, cycloheptene, or the like. Exemplified is saturated orunsaturated hetero ring containing 1 to 4 oxygen, sulfer, and/ornitrogen atom(s) in the hydrocarbon ring.

For example, a group of the formula: —C(R¹⁰R¹¹)—, wherein R¹⁰ and R¹¹taken together with the adjacent carbon atom to which they are attachedmay form an optionally substituted ring, is exemplified as follows.

“A ring formed by taking together R¹⁴ and R¹⁵ with the adjacent nitrogenatom to which they are attached” and “a ring formed by taking togetherR¹⁶ and R¹⁷ with the adjacent nitrogen atom to which they are attached”mean 3 to 15-membered nonaromatic hetero ring which may contain 1 to 4oxygen, sulfer, and/or nitrogen atom(s) besides the above nitrogen atomin the ring. The nonaromatic hetero ring can be bridged with C1 to C4alkyl chain and be fused with cycloalkane (preferred is 5 to 6-memberedring) or benzene ring. The ring can be saturated or unsaturated, as longas it is nonaromatic. Preferred is 5 to 8-membered ring. For example, agroup of the formula: —NR¹⁴R¹⁵ wherein R¹⁴ and R¹⁵ taken together withthe adjacent nitrogen atom to which they are attached may form anoptionally substituted ring and a group of the formula: —NR¹⁶R¹⁷ whereinR¹⁶ and R¹⁷ taken together with the adjacent nitrogen atom to which theyare attached may form an optionally substituted ring are exemplified asfollows. 1-Pyrrolinyl, 1-pyrrolidinyl, 1-imidazolinyl, 1-imidazolidinyl,1-pyrazolinyl, 1-pyrazolidinyl, piperidino, morpholino and the followinggroup are exemplified.

“Optionally substituted alkyl”, “optionally substituted alkenyl”,“optionally substituted alkynyl”, “optionally substituted cycloalkyl”,“optionally substituted cycloalkenyl”, “optionally substituted aryl”,“optionally substituted heteroaryl”, “optionally substitutedheterocycle”, “optionally substituted acyl”, “optionally substitutedalkoxycarbonyl”, “optionally substituted aralkylcarbonyl”, “optionallysubstituted alkoxy”, “optionally substituted alkylthio”, “optionallysubstituted alkylsulfonyl”, “optionally substituted arylsulfonyl”, “aring formed by taking together R⁴ and R⁵ with the adjacent nitrogen atomto which they are attached”, “a ring formed by taking together R⁷ and R⁸with the adjacent carbon atom to which they are attached”, “a ringformed by taking together R¹⁰ and R¹¹ with the adjacent carbon atom towhich they are attached”, “a ring formed by taking together R¹⁴ and R¹⁵with the adjacent nitrogen atom to which they are attached” and “a ringformed by taking together R¹⁶ and R¹⁷ with the adjacent nitrogen atom towhich they are attached” may be substituted with 1 to 4 substituent(s)selected from a group consisting of, for example, hydroxy, carboxy,halogen,

halogenated alkyl (e.g.: —CF₃, —CH₂CF₃, —CH₂CCl₃),alkyl (e.g.: methyl, ethyl, isopropyl, tert-butyl),alkenyl (e.g.: vinyl),alkynyl (e.g.: ethynyl),cycloalkyl (e.g.: cyclopropyl),cycloalkenyl (e.g.: cyclopropenyl),alkoxy (e.g.: methoxy, ethoxy, propoxy, butoxy),alkenyloxy (e.g.: vinyloxy, allyloxy),alkoxycarbonyl (e.g.: methoxycarbonyl, ethoxycarbonyl,tert-butoxycarbonyl), nitro, nitroso,optionally substituted amino (e.g.: alkylamino (e.g.: methylamino,ethylamino, dimethylamino), acylamino (e.g.: acetylamino, benzoylamino),aralkylamino (e.g.: benzylamino, tritylamino), hydroxyamino,alkyloxycarbonylamino, alkylsulfonylamino, optionally substitutedcarbamoylamino, heterocyclecarbonylamino, arylsulfonylamino), azide,aryl (e.g.: phenyl),aralky (e.g.: benzyl),cyano, isocyano, isocyanate, thiocyanate, isothiocyanate, mercapto,alkylthio (e.g.: methylthio),alkylsulfonyl (e.g.: methanesulfonyl, ethanesulfonyl),optionally substituted carbamoyl (e.g.: alkylcarbamoyl (e.g.:methylcarbamoyl, ethylcarbamoyl, dimethylcarbamoyl),alkylsulfonylcarbamoyl),sulfamoyl,acyl (e.g.: formyl, acetyl),formyloxy, haloformyl, oxalo, thioformyl, thiocarboxy,dithiocarboxy, thiocarbamoyl, sulfino, sulfo, sulfoamino, hydrazino,azide, ureido, amidino,guanidino, phthalimide, oxo,optionally substituted heteroaryl, heterocycle,alkylene,alkylenedioxy (—O—CH₂—O—, —O—CH₂—CH₂—O—, —O—CH₂—CH₂—CH₂—O—, or thelike), sulfonyl, sulfinyl, alkylcarbonyloxy, arylcarbonyloxy,heteroarylcarbonyloxy, heterocyclecarbonyloxy, alkylcarbonyl,arylcarbonyl, heteroarylcarbonyl, heterocyclecarbonyl, alkyloxycarbonyl,aryloxycarbonyl, heteroaryloxycarbonyl, heterocycleoxycarbonyl.

A substituent of “optionally substituted amino”, “optionally substitutedcarbamoyl”, “optionally substituted thiocarbamoyl” and “optionallysubstituted sulfamoyl” includes alkyl, alkenyl, aryl, heteroaryl,alkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, heterocyclecarbonyl,alkyloxycarbonyl, aryloxycarbonyl, heteroaryloxycarbonyl,heterocycleoxycarbonyl, sulfamoyl, alkylsulfonyl, carbamoyl,cycloalkylsulfonyl, arylsulfonyl, heteroarylsulfonyl,heterocyclesulfonyl, acyl, hydroxy, sulfonyl, sulfinyl, amino or thelike.

Among compounds of the present invention, the following embodiments arepreferable.

A compound represented by the formula (I):

is preferably a compound represented by the formula (II):

R¹ is a group of the formula: —C(═O)NR⁴R⁵,

-   -   wherein R⁴ and R⁵ are each independently, hydrogen, optionally        substituted alkyl, optionally substituted alkenyl, optionally        substituted alkynyl, optionally substituted cycloalkyl,        optionally substituted cycloalkenyl, optionally substituted        aryl, optionally substituted heteroaryl or optionally        substituted heterocycle; or R⁴ and R⁵ taken together with the        adjacent nitrogen atom to which they are attached may form an        optionally substituted ring or        a group of the formula: —NR⁶C(═O)R⁷,    -   wherein R⁶ is hydrogen, optionally substituted alkyl, optionally        substituted alkenyl, optionally substituted alkynyl, optionally        substituted cycloalkyl, optionally substituted cycloalkenyl,        optionally substituted aryl, optionally substituted heteroaryl,        optionally substituted heterocycle, optionally substituted        aralkyl or a group of the formula:—C(═O)R⁸,    -   R⁷ and R⁸ are each independently, hydrogen, optionally        substituted alkyl, optionally substituted alkenyl, optionally        substituted alkynyl, optionally substituted cycloalkyl,        optionally substituted cycloalkenyl, optionally substituted        aryl, optionally substituted heteroaryl or optionally        substituted heterocycle; or R⁷ and R⁸ taken together with the        adjacent carbon atom to which they are attached may form an        optionally substituted ring.

Preferably R¹ is a group of the formula: —C(═O)NR⁴R⁵ wherein R⁴ and R⁵have the same meaning as defined in the above.

More concretely R¹ is preferably

a group of the formula: —C(═O)NR⁴R⁵ wherein one of R⁴ and R⁵ isoptionally substituted cycloalkyl,a group of the formula: —C(═O)NR⁴R⁵ wherein one of R⁴ and R⁵ isoptionally substituted adamantyl ora group represented by the formula (III):

R² is optionally substituted alkyl, optionally substituted alkenyl,optionally substituted alkynyl, optionally substituted cycloalkyl,optionally substituted cycloalkenyl, optionally substituted aryl,optionally substituted heteroaryl, optionally substituted heterocycle,optionally substituted acyl or optionally substituted carbamoyl.

R² is preferably optionally substituted alkyl, optionally substitutedcycloalkyl, optionally substituted aryl, optionally substitutedheteroaryl or optionally substituted heterocycle.

More preferably R² is optionally substituted alkyl wherein thesubstituent of said optionally substituted alkyl does not encompass acyclic group,

optionally substituted alkenyl wherein the substituent of saidoptionally substituted alkenyl does not encompass a cyclic group,optionally substituted alkynyl wherein the substituent of saidoptionally substituted alkynyl does not encompass a cyclic group,optionally substituted acyl wherein the substituent of said optionallysubstituted acyl does not encompass a cyclic group oroptionally substituted carbamoyl wherein the substituent of saidoptionally substituted carbamoyl does not encompass a cyclic group.

Most preferably R² is optionally substituted alkyl wherein thesubstituent of said optionally substituted alkyl does not encompass acyclic group or branched alkyl.

R³ is optionally substituted alkyl, optionally substituted alkenyl,optionally substituted alkynyl, optionally substituted cycloalkyl,optionally substituted cycloalkenyl, optionally substituted aryl,optionally substituted heteroaryl, optionally substituted heterocycle,optionally substituted acyl, optionally substituted carbamoyl,optionally substituted thiocarbamoyl, optionally substituted amino,optionally substituted sulfamoyl or a group of the formula:—R⁹—C(R¹⁰R¹¹)—R¹²—R¹³,

-   -   R⁹ is —(CH₂)m-, wherein m is an integer of 0 to 3,    -   R¹⁰ and R¹¹ are each independently, hydrogen, optionally        substituted alkyl or halogen;    -   or R¹⁰ and R¹¹ taken together with the adjacent carbon atom to        which they are attached may form an optionally substituted ring,    -   R¹² is —(CH₂)n-, wherein n is an integer of 0 to 3,    -   R¹³ is hydrogen, hydroxy, carboxy, optionally substituted alkyl,        optionally substituted alkenyl, optionally substituted alkynyl,        optionally substituted cycloalkyl, optionally substituted        cycloalkenyl, optionally substituted aryl, optionally        substituted heteroaryl, optionally substituted heterocycle,        optionally substituted alkoxycarbonyl, optionally substituted        aralkylcarbonyl, optionally substituted carbamoyl, optionally        substituted thiocarbamoyl, optionally substituted alkylsulfonyl,        optionally substituted arylsulfonyl, optionally substituted        sulfamoyl, optionally substituted amino, optionally substituted        carbamoyloxy, optionally substituted alkoxy, optionally        substituted alkylthio,        a group of the formula: —C(═O)—NR¹⁴R¹⁵,    -   wherein R¹⁴ and R¹⁵ are each independently, hydrogen, optionally        substituted amino, optionally substituted alkyl, optionally        substituted alkenyl, optionally substituted alkynyl, optionally        substituted cycloalkyl, optionally substituted cycloalkenyl,        optionally substituted aryl, optionally substituted heteroaryl        or optionally substituted heterocycle; or R¹⁴ and R¹⁵ taken        together with the adjacent nitrogen atom to which they are        attached may form an optionally substituted ring or        a group of the formula: —NR¹⁶R¹⁷,    -   wherein R¹⁶ and R¹⁷ are each independently, hydrogen, carboxy,        hydroxy, optionally substituted alkyl, optionally substituted        alkenyl, optionally substituted alkynyl, optionally substituted        cycloalkyl, optionally substituted cycloalkenyl, optionally        substituted aryl, optionally substituted heteroaryl, optionally        substituted heterocycle, optionally substituted acyl, optionally        substituted carbamoyl, optionally substituted thiocarbamoyl,        optionally substituted alkylsulfonyl, optionally substituted        arylsulfonyl, optionally substituted alkyloxycarbonyl or        optionally substituted sulfamoyl; or R¹⁶ and R¹⁷ taken together        with the adjacent nitrogen atom to which they are attached may        form an optionally substituted ring.        R¹³ is preferably a group of the formula: —C(═O)—NR¹⁴R¹⁵    -   wherein R¹⁴ and R¹⁵ are each independently, hydrogen, optionally        substituted amino, optionally substituted alkyl, optionally        substituted alkenyl, optionally substituted alkynyl, optionally        substituted cycloalkyl, optionally substituted cycloalkenyl,        optionally substituted aryl, optionally substituted heteroaryl        or optionally substituted heterocycle; or R¹⁴ and R¹⁵ taken        together with the adjacent nitrogen atom to which they are        attached may form an optionally substituted ring or a group of        the formula: —NR¹⁶R¹⁷,    -   wherein R¹⁶ and R¹⁷ are each independently, hydrogen, carboxy,        hydroxy, optionally substituted alkyl, optionally substituted        alkenyl, optionally substituted alkynyl, optionally substituted        cycloalkyl, optionally substituted cycloalkenyl, optionally        substituted aryl, optionally substituted heteroaryl, optionally        substituted heterocycle, optionally substituted acyl, optionally        substituted carbamoyl, optionally substituted thiocarbamoyl,        optionally substituted alkylsulfonyl, optionally substituted        arylsulfonyl, optionally substituted alkyloxycarbonyl or        optionally substituted sulfamoyl; or R¹⁶ and R¹⁷ taken together        with the adjacent nitrogen atom to which they are attached may        form an optionally substituted ring.        More preferably R¹³ is a group of the formula: —C(═O)—NR¹⁴R¹⁵    -   wherein R¹⁴ and R¹⁵ are each independently, hydrogen, optionally        substituted amino, optionally substituted alkyl, optionally        substituted alkenyl, optionally substituted alkynyl, optionally        substituted cycloalkyl, optionally substituted cycloalkenyl,        optionally substituted aryl, optionally substituted heteroaryl        or optionally substituted heterocycle; or R¹⁴ and R¹⁵ taken        together with the adjacent nitrogen atom to which they are        attached may form an optionally substituted ring.

X is —O— or —S—.

Especially preferred as X is —O—.

Y is —O— or —S—.

Especially preferred as Y is —S—.

Z is a bond, —O— or —S—.

Z is preferably —O— or —S—, more preferably —O—.

As to a compound represented by the formula (I), the followingembodiments are particularly preferable.

R¹ is one selected from a group consisting of the substituent of thefollowing formula:

Moreover, R¹ is a group of the formula: —C(═O)NR⁴R⁵

-   -   wherein one of R⁴ and R⁵ is preferably optionally substituted        cycloalkyl, more preferably one selected from a group consisting        of the substituent of the following formula:

R² is optionally substituted alkyl, optionally substituted alkenyl,optionally substituted alkynyl, optionally substituted cycloalkyl,optionally substituted cycloalkenyl, optionally substituted aryl,optionally substituted heteroaryl, optionally substituted heterocycle,optionally substituted acyl or optionally substituted carbamoyl,R² is preferably optionally substituted alkyl, optionally substitutedcycloalkyl or optionally substituted aryl,More preferably R² is methyl, ethyl, n-propyl, isopropyl, n-butyl,isobutyl, —CH₂CH(CH₂CH₃)₂, —CH₂CF₃, cyclopentyl, cyclohexyl or phenyl,R³ is one selected from a group consisting of the substituent of thefollowing formula:

X and Y are each independently —O— or —S—,Z is a bond, —O— or —S—,preferably X is —O— or —S—, Y is —S—, and Z is —O—.

Pharmaceutically acceptable salts of the compounds of the presentinvention are exemplified as follows. Basic salts, for example, aresalts of alkali metal such as sodium, potassium or the like; salts ofalkaline-earth metal such as calcium, magnesium or the like; salts ofammonium; salts of aliphatic amine such as trimethylamine,triethylamine, dicyclohexylamine, ethanolamine, diethanolamine,triethanolamine, procaine, meglumine, diethanol amine, ethylenediamineor the like; salts of arylalkyl amine such asN,N-dibenzylethylenediamine, benetamine or the like; salts of heteroaromatic amine such as pyridine, picoline, quinoline, isoquinoline orthe like; salts of quaternary ammonium such as tetramethylammonium,tetraethylammonium, benzyltrimethylammonium, benzyltriethylammonium,benzyltributylammonium, methyltrioctylammonium, tetrabutylammonium orthe like; salts of basic amino acid such as arginine, lysine or thelike.

Acidic salts, for example, are salts of inorganic acid such ashydrochloric acid, sulfuric acid, nitric acid, phosphoric acid, carbonicacid, hydrogen carbonic acid, perchloric acid or the like; salts oforganic acid such as acetic acid, propionic acid, lactic acid, maleicacid, fumaric acid, tartaric acid, malic acid, citric acid or ascorbicacid; salts of sulfonic acid such as methansulfonic acid, isethionicacid, benzenesulfonic acid, p-toluenesulfonic acid or the like; salts ofacidic amino acid such as aspartic acid, glutamic acid or the like.

Solvate means a solvate of a compound of the present invention or apharmaceutically acceptable salt thereof, for example, alcohol (e.g.,ethanol) solvate, hydrate or the like. As to hydrate, monohydrate,dihydrate or the like are exemplified.

A general method for producing a compound of the present invention isexplained below. Each symbol is the same meanings as the above (1). Inaddition, the treatment of the conventional organic synthesis such asextraction, purification and the like can be used for the synthesis of acompound of the present invention.

Each symbol in the above scheme is the same meanings as the above. As tocompound (IV-1), well known compounds and compounds, which are lead fromwell-known compounds by usual methods, can be used. Bn is benzyl group.

1^(st) Step

1^(st) step is a process for manufacturing a compound of the formula(IV-2) which comprises reacting a compound of the formula (IV-1) withR²SSR² in the presence of a base.

This reaction can be performed in a solvent of N-dimethylformamide,dimethyl sulfoxide, aromatic hydrocarbon group (for example, toluene,benzene, xylene or the like), saturated hydrocarbon group (for example,cyclohexane, hexane or the like), halogenated hydrocarbon group (forexample, dichloromethane, chloroform, 1,2-dichloroethane or the like),ether group (for example, tetrahydrofuran, diethyl ether, dioxane,1,2-dimethoxyethane or the like), ketone group (for example, acetone,methyl ethylketone or the like), nitryl group (for example, acetonitrileor the like), alcohol group (for example, methanol, ethanol, t-butanolor the like), water, a mixed solvent thereof or the like under thepresence of n-BuLi, R²SSR².

This reaction can be preferably performed in a solvent of ether group(e.g., tetrahydrofuran, diethyl ether, dioxane or the like) as a solventat −78° C.-20° C. for 0.5-5 hours.

2^(nd) Step

2^(nd) step is a process for manufacturing a compound of the formula(IV-3) which comprises amidating a compound of the formula (IV-2).

This reaction can be performed in an appropriate solvent under thepresence of HOBT, WSC, a base, R⁴R⁵NH.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

The base is, for example, metal hydride (for example, sodium hydride orthe like), metal hydroxide (for example, sodium hydroxide, potassiumhydroxide, lithium hydroxide, barium hydroxide or the like), metalcarbonate (for example, sodium carbonate, calcium carbonate, cesiumcarbonate or the like), metal alkoxide (for example, sodium methoxide,sodium ethoxide, potassium tert-butoxide or the like), sodium hydrogencarbonate, metallic sodium, organic amine (for example, triethylamine,diisopropylethylamine, DBU, 2,6-lutidine or the like) or the like.

Preferably this reaction can be performed in a solvent ofN-dimethylformamide, ether group (e.g., tetrahydrofuran, diethyl ether,dioxane or the like) as a solvent under the presence of organic amine(for example, triethylamine, diisopropylethylamine or the like) at 20°C.-100° C. for 0.5-24 hours.

3^(rd) Step

3^(rd) step is a process for manufacturing a compound of the formula(IV-4) which comprises deprotecting a protective group of a compound ofthe formula (IV-3).

This reaction can be performed under the presence of a mixture ofhydrogen bromide and acetic acid, anisole at 0° C.-50° C. for 0.5-24hours.

4^(th) Step

4^(th) step is a process for manufacturing a compound of the formula(I-1) which comprises putting a compound of the formula (IV-4) inMitsunobu reaction.

This reaction can be performed in an appropriate solvent under thepresence of R³—OH, DIAD and PPh₃.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent of ether group(e.g., tetrahydrofuran, diethyl ether, dioxane or the like) as a solventat −30° C.-80° C. for 0.5-24 hours.

Pro is a protecting group and the other symbols are the same meanings asthe above. As to compound (IV-5), well known compounds and compounds,which are lead from well-known compounds by usual methods, can be used.Pro is benzyl group, triphenylmethyl group or the like.

5^(th) Step

5^(th) step is a process for manufacturing a compound of the formula(IV-6) which comprises putting a compound of the formula (IV-5) in thesame reaction as the above 1^(st) step.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent of ether group(e.g., tetrahydrofuran, diethyl ether, dioxane or the like) as a solventat −78° C.-20° C. for 0.5-5 hours.

6^(th) Step

6^(th) step is a process for manufacturing a compound of the formula(IV-7) which comprises putting a compound of the formula (IV-6) in thesame reaction as the above 2^(nd) step.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

As the base, the same base described in the above 2^(nd) step can beused.

Preferably this reaction can be performed in a solvent ofN-dimethylformamide, ether group (e.g., tetrahydrofuran, diethyl ether,dioxane or the like) as a solvent under the presence of organic amine(for example, triethylamine, diisopropylethylamine or the like) as abase at 20° C.-100° C. for 0.5-24 hours.

7^(th) Step

7^(th) step is a process for manufacturing a compound of the formula(IV-8) which comprises oxidizing a compound of the formula (IV-7).

This reaction can be performed in an appropriate solvent under thepresence of sodium periodate.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a mixed solvent of dioxane,methanol and water as a solvent at 20° C.-80° C. for 0.5-72 hours.

8^(th) Step

8^(th) step is a process for manufacturing a compound of the formula(IV-9) which comprises putting a compound of the formula (IV-8) inPummerer rearrangement.

This reaction can be performed in an appropriate solvent under thepresence of 2,6-lutidine, trifluoroacetic anhydride, base.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

As the base, the same base described in the above 2^(nd) step can beused.

Preferably this reaction can be performed in a solvent of halogenatedhydrocarbon group (for example, dichloromethane, chloroform or the like)as a solvent or without any solvent under the presence of organic amine(for example, triethylamine, diisopropylethylamine or the like) as abase at −30° C.-80° C. for 0.5-24 hours.

9^(th) Step

9^(th) step is a process for manufacturing a compound of the formula(IV-10) which comprises alkylating a compound of the formula (IV-9).

This reaction can be performed in an appropriate solvent under thepresence of R²-Hal, a base.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

As the base, the same base described in the above 2^(nd) step can beused.

Preferably this reaction can be performed in a solvent ofN-dimethylformamide, acetonitrile, acetone or a mixed solvent thereof asa solvent under the presence of metal carbonate (for example, calciumcarbonate, cesium carbonate or the like) as a base at −30° C.-100° C.for 0.5-24 hours.

10^(th) Step

10^(th) step is a process for manufacturing a compound of the formula(I-2) which comprises deprotecting a protective group of a compound ofthe formula (IV-10) and then putting in Mitsunobu reaction.

Deprotection reaction and Mitsunobu reaction can be performed by awell-known method, preferably by the method described in the above3^(rd) step and 4^(th) step.

Each symbol in the above scheme is the same meanings as the above. As tocompound (IV-11), well known compounds and compounds, which are leadfrom well-known compounds by usual methods, can be used.

11^(th) Step

11^(th) step is a process for manufacturing a compound of the formula(IV-12) which comprises formylating a compound of the formula (IV-11).

This reaction can be performed in an appropriate solvent under thepresence of n-BuLi and DMF.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent ofN-dimethylformamide, ether group (e.g., tetrahydrofuran, diethyl ether,dioxane or the like) as a solvent at −78° C.-30° C. for 0.5-24 hours.

12^(th) Step

12^(th) step is a process for manufacturing a compound of the formula(IV-13) which comprises putting a compound of the formula (IV-12) inBaeyer-Villiger oxidation.

This reaction can be performed in an appropriate solvent under thepresence of oxidant such as MCPBA, hydrogen peroxide solution or thelike.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent of alcohol group(for example, methanol, ethanol or the like), water, halogenatedhydrocarbon group (for example, dichloromethane, chloroform or the like)as a solvent at −78° C.-30° C. for 0.5-24 hours.

13^(th) Step

13^(th) step is a process for manufacturing a compound of the formula(IV-14) which comprises hydrolyzing a compound of the formula (IV-13).

This reaction can be performed in an appropriate solvent under thepresence of a base.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent of alcohol group(for example, methanol, ethanol or the like), water as a solvent underthe presence of metal hydroxide (for example, sodium hydroxide,potassium hydroxide or the like) as a base at 0° C.-100° C. for 0.5-24hours.

14^(th) Step

14^(th) step is a process of manufacturing a compound of the formula(I-3) which comprises putting a compound of the formula (IV-14) inMitsunobu reaction.

Mitsunobu reaction can be performed by a well-known method, preferablyby the method described in the above 4^(th) step.

wherein LG is a leaving group and the other symbols are the samemeanings as the above. As to compound (IV-15), well known compounds andcompounds, which are lead from well-known compounds by usual methods,can be used. LG is, for example, mesyl group, tosyl group or the like.

15^(th) Step

15^(th) step is a process for manufacturing a compound of the formula(IV-16) which comprises introducing a leaving group into a compound ofthe formula (IV-15).

This reaction can be performed in an appropriate solvent under thepresence of Tf₂O, MsCl or the like.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent of halogenatedhydrocarbon group (for example, dichloromethane, chloroform or the like)as a solvent at −78° C.-30° C. for 0.5-24 hours.

16^(th) Step

16^(th) step is a process for manufacturing a compound of the formula(I-4) which comprises putting a compound of the formula (IV-16) inSuzuki-coupling.

This reaction can be performed in an appropriate solvent under thepresence of R³—B(OH)₂, palladium catalyst (for example, Pd(PPh₃)₄ or thelike).

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent ofN-dimethylformamide, 1,2-dimethoxyethane, alcohol group (for example,methanol, ethanol or the like), water or a mixed solvent thereof as asolvent at 20° C.-100° C. for 0.5-24 hours.

Each symbol in the above scheme is the same meanings as the above. As tocompound (IV-15), well known compounds and compounds, which are leadfrom well-known compounds by usual methods, can be used.

17^(th) Step

17^(th) step is a process for manufacturing a compound of the formula(IV-17) which comprises halogenating a compound of the formula (IV-15).

This reaction can be performed in an appropriate solvent under thepresence of phosphorous[phosphorus]oxychloride, sulfonyl chloride,carbon tetrabromide or the like.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent of halogenatedhydrocarbon group (for example, dichloromethane, chloroform or the like)as a solvent or without any solvent at −30° C.-150° C. for 0.5-24 hours.

18^(th) Step

18^(th) step is a process for manufacturing a compound of the formula(I-5) which comprises reacting a compound of the formula (IV-17) withR³ZH.

This reaction can be performed in an appropriate solvent under thepresence of R³ZH and a base.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

As the base, the same base described in the above 2^(nd) step can beused.

Preferably this reaction can be performed in a solvent ofN-dimethylformamide, ether group (e.g., tetrahydrofuran, diethyl ether,dioxane or the like) as a solvent under the presence of metal hydride(for example, sodium hydride or the like), metal alkoxide (for example,sodium methoxide, sodium ethoxide, potassium tert-butoxide or the like),as a base at −78° C.-80° C. for 0.5-24 hours.

Each symbol in the above scheme is the same meanings as the above. As tocompound (IV-18), well known compounds and compounds, which are leadfrom well-known compounds by usual methods, can be used.

19^(th) Step

19^(th) step is a process for manufacturing a compound of the formula(I-6) which comprises reacting a compound of the formula (IV-18) withR⁷COCl.

This reaction can be performed in an appropriate solvent under thepresence of R⁷COCl.

As the solvent, the same solvent described in the above 1^(st) step canbe used.

Preferably this reaction can be performed in a solvent of halogenatedhydrocarbon group (for example, dichloromethane, chloroform or thelike), ether group (for example, tetrahydrofuran, diethyl ether, dioxaneor the like), N-dimethylformamide as a solvent at −30° C.-100° C. for0.5-24 hours.

The abbreviations used in the each stage are as follows.

DBU 1,8-Diazabicyclo[5.4.0]undec-7-enen-BuLi n-Butyllithium

HOBT 1-Hydroxybenzotriazole

WSC 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimideDIAD Azodicarboxylic acid diisopropyl

PPh₃ Triphenylphosphine

Tf₂O Trifluoroacetic anhydrideMCPBA m-chloroperbenzoic acid

If necessary, after hydroxy or thiol group of a compound is protected bythe usual method at an appropriate step, it is subjected to the reactionand then deprotected by the usual method at an appropriate step.

As a protecting group, alkyl (methyl, ethyl or the like), aralkyl(benzyl, p-methoxybenzyl, triphenylmethyl or the like), trialkyl silyl(t-butyldimethylsilyl, t-butyldiphenylsilyl or the like), acetyl groupor the like can be used.

Various substituent of a compound of the present invention can beintroduced referring to (1) Alan R. Katriszly et al., ComprehensiveHeterocyclic Chemistry, (2) Alan R. Katriszly et al., ComprehensiveHeterocyclic Chemistry II, (3) RODD'S CHEMISTRY OF CARBON COMPOUNDSVOLUME IV HETEROCYCLIC COMPOUNDS, or the like.

A compound of the present invention has a high inhibitory activity on11β-hydroxysteroid dehydrogenase type 1. Therefore, a compound of thepresent invention can be used for treating and/or preventing a diseaseconcerning 11β-hydroxysteroid dehydrogenase type 1, especially,hyperlipidemia, diabetes, obesity, arteriosclerosis, atherosclerosis,hyperglycemia and/or syndrome X. Especially, a compound of the presentinvention is useful for treating and/or preventing diabetes.

A compound of the present invention can be administrated orally orparenterally. For oral administration, the compound of the presentinvention can be used in any form of the conventional pharmaceuticalformulations, for example, solid formulations such as tablets, powders,granules, capsules or the like; aqueous formulations; oleaginoussuspensions; or solution formulations such as syrup or elixir. Forparenteral administration, the compound of the present invention can beused as an aqueous or oleaginous suspension injections or nose drops. Inthe preparation of such formulations, the conventional pharmaceuticalexcipients, binding agents, lubricants, aqueous solvents, oleaginoussolvents, emulsifying agents, suspending agents, preservatives,stabilizers, and the like can be optionally used. Especially, a compoundof the present invention is preferably used as oral agents.

A formulation according to the present invention can be manufactured bycombining (e.g., admixing) a curatively effective amount of a compoundof the present invention with a pharmaceutically acceptable carrier ordiluent. The formulation can be manufactured by using of well-known andeasily available ingredients in accordance with a known method.

A dosage of a compound of the present invention depends on theadministration route, age, body weight, conditions of the patient, andkind of disease, but in case of oral administration, the daily dosagefor an adult can be between approximately 0.05 mg˜3000 mg, preferablyapproximately 0.1 mg˜1000 mg. The daily dosage can be administered indivisions. When a compound of the present invention is administratedparenterally, the daily dosage for an adult can be between approximately0.01 mg˜11000 mg, preferably approximately 0.05 mg˜500 mg. Moreover, acompound of the present invention can be administrated with othercurative agents.

Examples are shown below for further detail explanation of the presentinvention, but are not intended to limit the scope of the presentinvention.

The abbreviations used in the examples are as follows.

Boc t-Butoxycarbonyl

TEA Triethylamine

TFA Trifluoroacetic acidBnBr Benzyl bromide

EXAMPLE 1

To a solution of Compound 1 (12 g) in tetrahydrofuran (240 ml) wereadded N-Boc-4-piperidinemethanol (18 g) and triphenylphosphine (22 g).Azodicarboxylic acid diisopropyl (16.5 ml) was added dropwisely to thesolution, then the reaction solution was stirred at room temperature for2 hrs. After termination of the reaction, the solvent was removed andthe residue was purified by silicagel columnchromatography to giveCompound 2. According to the above procedure, the obtained 2 wasdissolved in tetrahydrofuran (200 ml) and methanol (100 ml), and then 2NLiOH aqueous soln. (65 ml) was added to the resulting solution. Thesolution was stirred at room temperature for 1 hr. After termination ofthe reaction, tetrahydrofuran and methanol were removed. The solutionwas diluted with H₂O and the aqueous layer was washed with diethylether.The mixture was acidified with 2N HCl aqueous soln., and extracted withethyl acetate. The organic layer was washed with brine and dried withsodium sulfate and concentrated to give Compound 3 (21.6 g).

To a solution of Compound 3 (21.6 g) in tetrahydrofuran (500 ml) wasadded n-butyllithium (1.57M in hexane, 100 ml) dropwisely at −78° C.After stirring at −78° C. for 10 min, the whole mixture was stirred atroom temperature for 30 min. After cooling again to −78° C., dimethyldisulfide (6.9 ml) was added dropwisely to the solution and the reactionsolution was stirred at room temperature for 3 hrs. After termination ofthe reaction, conc. HCl (14 ml) was added to the reaction solution andthe solution was stirred for 10 min. The solution was adjusted to pH 8by 2N NaOH aqueous soln. And washed with diethylether. The aqueous layerwas acidified with conc. H₂SO₄, and extracted with ethyl acetate. Theorganic layer was washed with brine and dried with sodium sulfate andconcentrated to give Compound 4 (23.9 g).

Under N₂ atmosphere, to a solution of Compound 4 (23.9 g) indimethylformamide (400 ml) was added 2-adamantanamine hydrochloride(13.3 g), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride(14.8 g) and 1-hydroxybenzotriazole (9.2 g), then triethylamine (23.2ml) was slowly added dropwisely to the solution. The resulting solutionwas stirred at room temperature for 24 hrs. After termination of thereaction, the solution was poured into 2N HCl aqueous soln. (400 ml) andice (300 ml), then extracted with ethyl acetate. The extraction waswashed with sat. sodium hydrogencarbonate soln. and brine successively,then dried with sodium sulfate and concentrated. The residue waspurified by silicagel columnchromatography to give Compound 5 (28.2 g).Compound 5a was obtained by deprotecting Compound 5 under acidcondition. The reaction of Compound 5a with bromoethanol gave Compound5b.

5a: ¹H-NMR (CDCl₃): 1.65-2.1 (m, 19H), 2.20 (m, 1H), 2.46 (s, 3H), 2.96(m, 2H), 3.58 (brd, J=16.4 Hz, 1H), 4.27 (d, J=8.4 Hz, 2H), 7.64 (d,J=6.8 Hz, 1H), 9.47 (m, 1H), 9.73 (m, 1H)

5b: ¹H-NMR (CDCl₃): 1.4-1.6 (m, 2H), 1.65-2.1 (m, 18H), 2.17 (dt, J=2.1,11.7 Hz, 2H), 2.46 (s, 3H), 2.59 (t, J=5.4 Hz, 2H), 2.7 (brs, 1H), 3.02(brd, J=11.7 Hz, 2H), 3.65 (t, J=5.4 Hz, 2H), 4.21 (d, J=6.6 Hz, 1H),4.27 (brd, J=8.1 Hz, 1H), 7.64 (d, J=8.4 Hz, 1H)

To a solution of Compound 5 (7.83 g) in chloroform (60 ml) was addedm-chloroperbenzoic acid (content of about 70%, 3.8 g), then theresulting mixture was stirred at room temperature for 30 min. Aftertermination of the reaction, the organic layer was washed with sat.sodium hydrogencarbonate soln. and brine successively, and dried withsodium sulfate and concentrated to give Compound 6 (7.67 g).

To a solution of Compound 6 (19.7 g) in chloroform (100 ml) was added2,6-lutidine (24.3 g) under N₂ atmosphere, and trifluoroacetic anhydride(21.3 ml) was added dropwisely to the resulting mixture underice-cooling. The solution was stirred at 50° C. for 1 hr, and chloroformwas removed. Methanol (80 ml) and triethylamine (20 ml) were added tothe residue, and the solution was stirred at room temperature for 1 hr.After termination of the reaction, the solution was acidified with 2NHCl aqueous soln., and extracted with ethyl acetate. The organic layerwas washed with brine and dried with magnesium sulfate and concentrated.The residue (7) was dissolved in dimethylformamide (120 ml), andisopropyl bromide (18.5 g) and cesium carbonate (48.6 g) were added tothe solution. The solution was stirred at room temperature for 14 hrs.After termination of the reaction, the solution was poured into ice-coldwater and extracted with ethyl acetate. The organic layer was washedwith brine and dried with magnesium sulfate and concentrated. Theresidue was purified by silicagel columnchromatography to give Compound8b (14.2 g).

To a solution of Compound 8b (7.31 g) in chloroform (70 ml) was addedtrifluoroacetic acid (10 ml), and the resulting mixture was stirred atroom temperature for 2 hrs. After termination of the reaction, thesolvent was removed and the residue was diluted with ethyl acetate. Theorganic layer was washed with sodium carbonate soln. and brinesuccessively, and dried with magnesium sulfate and concentrated. Theresidue was dissolved in diethylether, and hydrochloride was formed byadding 0.02M HCl (diethylether soln.) to the solution. The resultingpowder was collected by filtration and dried to give Compound 9b (3.91g).

The above-mentioned examples are concerning Compound 9b. Compounds 9a,9c˜9g were synthesized in accordance with the method shown in the aboveexamples.

TABLE 1 No. R² NMR 9a Et (DMSO-d6); 1.14 (t, J = 7.2 Hz, 3H), 1.45-2.05(m, 16H), 2.14 (m, 1H), 2.84 (m, 2H), 2.90 (m, 2H), 3.30 (m, 2H), 4.03(brs, 1H), 4.19 (d, J = 6.0 Hz, 2H), 8.39(d, J = 7.2 Hz, 1H), 8.86 (m,1H), 9.16 (m, 1H) 9b i-Pr (DMSO-d6); 1.29 (d, J = 6.4 Hz, 6H), 1.45-2.05(m, 18H), 2.14 (m, 1H), 2.88 (m, 2H), 3.28 (m, 2H), 4.03 (brs, 1H), 4.19(d, J = 5.2 Hz, 2H), 8.43(d, J = 7.6 Hz, 1H), 8.81 (m, 1H), 9.09 (m, 1H)9c n-Pr (DMSO-d6); 0.91 (t, J = 7.2 Hz, 3H), 1.4-2.05 (m, 22H), 2.16 (m,1H), 2.81 (t, J = 7.2 Hz, 2H), 2.90 (m, 2H), 4.03 (brs, 1H), 4.20 (d, J= 6.0 Hz 2H), 8.40 (d, J = 6.8 Hz, 1H), 8.61 (m, 1H), 8.92 (m, 1H) 9dn-Bu (DMSO-d6); 0.83 (t, J = 7.2 Hz, 3H), 1.33 (m, 2H), 1.4-2.05 (m,16H), 2.12 (m, 1H), 2.83 (t, J = 6.8 Hz, 2H), 2.90 (m, 2H), 3.29 (m,2H), 4.03 (brs, 1H), 4.19 (d, J = 6.0 Hz, 2H), 8.38(d, J = 6.4 Hz, 1H),8.73 (m, 1H), 9.07 (m, 1H) 9e —CH₂CF₃ (DMSO-d6); 1.45-2.1 (m, 20H), 2.16(m, 1H), 2.90 (m, 2H), 3.80 (m, 2H), 4.02 (brs, 1H), 4.19 (d, J = 6.4Hz, 2H), 8.44 (d, J = 7.2 Hz, 1H), 8.69 (m, 1H), 8.96 (m, 1H) 9f i-Bu(DMSO-d6); 0.92 (d, J = 6.8 Hz, 6H) 1.45-2.05 (m, 15H), 2.15 (m, 1H),2.73 (d, J = 6.4 Hz, 2H), 2.91 (m, 2 H ), 3.28 (brd J = 11.6 Hz, 2H),3.78 (m, 1H), 4.03 (m, 1H), 4.19 (d, J = 6.0 Hz, 2H), 8.39 (d, J = 6.8Hz, 1H), 8.84 (m, 1H), 9.12 (m, 1H) 9g —CH₂CH(CH₂CH₃)₂ (DMSO-d6); 0.79(d, J = 6.8 Hz, 6H) 1.25-2.05 (m, 23H), 2.15 (m, 1H), 2.82 (d, J = 4.8Hz, 2H), 2.90 (m, 2H), 3.29 (m, 2H), 4.02 (brs, 1H), 4.19 (d, J = 6.0Hz, 2H), 8.37 (d, J = 7.6 Hz, 1H), 8.71 (m, 1H), 9.01 (m, 1H)

EXAMPLE 2

Compounds 12a˜12j were synthesized in accordance with theabove-mentioned scheme.

TABLE 2 No. R² R⁵ NMR 12a i-Pr H (DMSO-d6); 0.82 (s, 3H), 0.85 (s, 3H),0.97 (s, 3H), 1.18 (t, J = 7.6 Hz, 6H), 1.45-2.0 (m, 12H), 2.14 (m, 1H),2.91 (m, 2H), 3.30 (m, 2H), 3.91 (brs, 1H), 4.17 (d, J = 5.6 Hz, 2H),7.99 (d, J = 7.6 Hz, 1H), 8.72 (m, 1H), 9.00 (m, 1H) 12b i-Pr H(DMSO-d6); 1.20 (d, J = 6.8 Hz, 6H), 1.53 (brt, J = 13.2 Hz, 6H)1.80-1.89 (m, 13H), 2.14 (m, 1H), 2.88 (m, 2H), 3.30 (m, 2H), 3.86 (m,1H), 4.18 (d, J = 6.8 Hz, 2H), 8.37 (brd, J = 7.2 Hz, 1H), 8.87 (m, 1H),9.15 (m, 1H) 12c i-Pr H (DMSO-d6); 1.18 (d, J = 6.4 Hz, 6H), 1.3-2.4 (m,9H), 2.45 (t, J = 11.2 Hz, 1H), 2.93 (brd, J = 12.4 Hz, 2H), 3.38 (m,1H), 3.95 (m, 1H), 4.11 (d, J = 5.2 Hz, 2H), 4.34 (m, 1H), 4.77 (m, 1H),6.08 (t, J = 8.4 Hz, 1H), 6.36(t, J = 8.4 Hz, 1H), 8.31(s, 2H), 8.35(m,1H), 8.44 (m, 1H), 8.61(brd, J = 5.2 Hz, 1H), 8.86 (brs, 1H) 12d i-Pr H(DMSO-d6); 0.78 (s, 3H), 0.86 (s, 3H), 0.93 (s, 3H), 1.0-1.6 (m, 14H),1.65 (brs, 1H), 1.69 (m, 2H), 1.87 (m, 2H), 2.15 (m, 2H), 2.92 (m, 2H),4.19 (brd, J = 6.0 Hz, 2H), 4.25 (m, 1H), 8.53 (d, J = 8.4 Hz, 1H), 8.65(m, 1H), 8.94 (m, 1H) 12e i-Pr H (DMSO-d6); 1.17 (d, J = 5.6 Hz, 6H),1.3-1.7(m, 15H), 1.7-2.1 (m, 4H), 2.13 (m, 1H), 2.89 (brd, J = 10.8 Hz,2H), 3.98 (brs, 1H), 4.18 (d, J = 4.4 Hz, 2H), 8.59 (d, J = 6.8 Hz, 1H),8.74 (m, 1H), 9.01 (m, 1H) 12f i-Pr H (DMSO-d6); 1.18 (d, J = 6.4 Hz,6H), 1.26(q, J = 11.6 Hz, 2H), 1.41 (d, J = 12.4 Hz, 2H), 1.55-1.8 (m,10H), 1.86 (d, J = 12.4 Hz, 2H), 1.96 (brs, 1H), 2.06 (brs, 2H), 2.60(t, J = 12.0 Hz, 2H), 3.05 (d, J = 11.6 Hz, 2H), 3.30 (m, J = 6.4 Hz,1H), 3.73 (brs, 1H), 3.94 (brs, 1H), 4.13 (d, J = 6.4 Hz, 2H), 8.37 (d,J = 6.8 Hz, 1H) 12g n-Pr H (DMSO-d6); 0.81 (s, 3H), 0.84 (s, 3H), 0.91(t, J = 7.6 Hz, 3H), 0.96 (s, 3H), 1.04 (d, J = 6.0 Hz, 1H), 1.88 (m,2H), 1.35-1.9 (m, 10H), 2.13 (brs, 1H), 2.80 (m, 2H), 2.88 (m, 2H), 3.30(m, 2H), 3.92 (m, 1H), 4.18 (d, J = 6.0 Hz, 1H), 7.97 (d, J = 8.4 Hz,1H), 8.74 (m, 1H), 9.05 (m, 1H) 12h n-Pr H (DMSO-d6); 0.91(t, J = 7.6Hz, 3H), 1.04 (d, J = 6.4 Hz, 1H), 1.4-2.0 (m, 18 H), 2.13 (brs, 1H),2.82 (t, J = 6.8 Hz, 2H), 2.90 (m, 2H), 3.28 (d, J = 12.4 Hz, 2H), 3.60(m, 1H), 3.85 (brs, 1H), 4.18 (d, J = 6.0 Hz, 2H), 8.34 (d, J = 7.2 Hz,1H), 8.95 (m, 1H), 9.22 (m, 1H) 12i n-Pr H (DMSO-d6); 0.91 (t, J = 7.6Hz, 3H), 1.20 (m, 2H), 1.3-2.4 (m, 9H), 2.49 (t, J = 12.8 Hz, 1H),2.81(brt, J = 6.8 Hz, 2H), 2.96 (brd, J = 11.6 Hz, 2H), 3.94 (m, 1H),4.11 (d, J = 6.0 Hz, 2H), 4.33 (m, 1H), 4.43 (m, 1H), 6.14 (t, J = 8.4Hz, 1H), 6.41 (t, J = 8.4 Hz, 1H), 8.24 (brd, J = 7.6 Hz, 1H), 8.31(s,2H), 8.38 (brd, J = 7.2 Hz, 1H), 8.63 (d, J = 6.8 Hz, 2H) 12j n-Pr HFree (DMSO-d6); 0.90 (t, J = 7.6 Hz, 3H), 1.03(d, J = 6.4 Hz, 1H), 1.17(m, 2H), 1.35-1.9 (m, 16H), 2.02 (brs, 1H), 2.07 (brs, 2H), 2.45 (m,1H), 2.79 (t, J = 6.8 Hz, 2H), 2.94(m, 2H), 3.93 (s, 1H), 4.18(d, 2H),8.31(m, 1H)

EXAMPLE 3

To a solution of Compound 1 (14 g) in dimethylformamide (140 ml) wasadded potassium carbonate (19 g), then the resulting mixture was stirredat 70° C. for 1 hr. Benzyl bromide (18 ml) was slowly added dropwiselyto the reaction mixture at 70° C. and the reaction solution was stirredfor 3 hrs. After termination of the reaction, the reaction solution waspoured into ice-cold water and extracted with ethyl acetate. The organiclayer was washed with brine and dried with magnesium sulfate andconcentrated. The residue (13) was dissolved in tetrahydrofuran (100ml)-methanol (100 ml), and 1N lithium hydroxide aqueous soln. (200 ml)was added to the resulting solution. The solution was stirred at roomtemperature for 14 hrs. After termination of the reaction, the solutionwas diluted with H₂O and the aqueous layer was washed with diethylether.The mixture was acidified with 2N HCl aqueous soln., and extracted withethyl acetate. The organic layer was washed with brine and dried withsodium sulfate and concentrated. The residue was washed with hexane togive Compound 14 (21.9 g).

To a solution of Compound 14 (14 g) in tetrahydrofuran (1.2 L) wasslowly added n-butyllithium (1.57M in n-hexane, 100 ml) dropwisely at−78° C. After stirring at room temperature for 1 hr, the resultingsolution was cooled again to −78° C. Dimethyl disulfide (8.1 ml) wasadded to the solution and the reaction solution was stirred at roomtemperature for 2 hrs. After termination of the reaction, the solutionwas diluted with H₂O and the mixture was acidified with 2N HCl aqueoussoln. The solution was extracted with ethyl acetate and dried withsodium sulfate and concentrated. The residue was washed with diisopropylether-hexane to give Compound 15 (11.9 g).

To a solution of Compound 15 (17 g) in dimethylformamide (377 ml) wereadded 2-adamantanamine hydrochloride (14.4 g),1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (18.4 g) and1-hydroxybenzotriazole (1.73 g) under N₂ atmosphere, then triethylamine(24.1 ml) was slowly added dropwisely to the solution. The resultingsolution was stirred at room temperature for 5 hrs. After termination ofthe reaction, the solution was poured into 2N HCl aqueous soln. (400 ml)and ice (300 ml), then extracted with ethyl acetate. The extraction waswashed with sat. sodium hydrogencarbonate soln. and brine successively,then dried with sodium sulfate and concentrated. The residue waspurified by silicagel columnchromatography to give Compound 16 (21.1 g).

Compound 16 (21 g) was dissolved in dioxane (420 ml)-methanol (210ml)-H₂O (210 ml), and then sodium periodate (47.3 g) was added to theresulting solution. The solution was stirred at 55° C. for 48 hrs. Aftertermination of the reaction, dioxane and methanol were removed. Thesolution was diluted with H₂O and extracted with chloroform. The organiclayer was washed with brine and dried with sodium sulfate andconcentrated. The residue was recrystallized from ethyl acetate-hexaneto give Compound 17 (16.5 g).

Under N₂ atmosphere, 2,6-lutidine (30 g) was added To Compound 17 (17.6g) and the resulting mixture was suspended. Trifluoroacetic anhydride(25.8 ml) was added dropwisely to the resulting mixture over 15 minunder ice-cooling. The resulting solution was stirred at 60° C. for 1hr, and the solution was removed. Under N₂ atmosphere, methanol (141 ml)was added to the residue under ice-cooling, and triethylamine (28 ml)was added dropwisely to the resulting solution. The resulting solutionwas stirred at room temperature for 3 hrs. After termination of thereaction, the solution was poured into 2N NaOH aqueous soln. and ice andwashed with diethylether. The aqueous layer was acidified with 2N HClaqueous soln., and extracted with ethyl acetate. The organic layer waswashed with brine and dried with sodium sulfate and concentrated to giveCompound 18.

Compound 18 was dissolved in dimethylformamide (54 ml) and acetonitrile(54 ml) under N₂ atmosphere, and cesium carbonate (34.3 g) was added tothe resulting solution under ice-cooling. 2-Bromopropane (7.9 ml) wasadded to the solution and the solution was stirred at room temperaturefor 24 hrs. After termination of the reaction, the solution was pouredinto ice-cold water. The resulting mixture was acidified with 2N HClaqueous soln., and extracted with ethyl acetate. The organic layer waswashed with brine and dried with sodium sulfate and concentrated to giveCompound 19a (12.0 g).

Anisole (30.5 ml) was added to Compound 19a (12.0 g). 25% HBr/AcOH (120ml) was added to the resulting mixture. The solution was stirred at roomtemperature for 4 hrs.

After termination of the reaction, the reaction solution was poured intoice water, and extracted with ethyl acetate. The solution was washedwith brine, and dried with sodium sulfate and concentrated. Hexane wasadded to the residue, and the resulting crystal was collected byfiltration to give Compound 20a (8.8 g).

To a solution of Compound 20a (8.8 g) in tetrahydrofuran (180 ml) wereadded triphenylphosphine (11 g) and hydroxypivalic acid methyl ester(5.5 g) under N₂ atmosphere. Azodicarboxylic acid diisopropyl (8.3 ml)was added dropwisely to the solution, then the whole mixture was stirredat room temperature for 3 hrs. After termination of the reaction, thesolvent was removed. Diethylether was added to the residue and theobtained triphenylphosphine oxide was removed. Diethylether was removedand the residue was purified by silicagel columnchromatography to giveCompound 21a (9.55 g).

Compound 21a (11.1 g) was dissolved in tetrahydrofuran (84 ml)-methanol(42 ml), and 2N lithium hydroxide aqueous soln. (24.7 ml) was added tothe resulting solution. The solution was stirred at room temperature for8 hrs and at 50° C. for 2 hrs. After termination of the reaction,tetrahydrofuran and methanol were removed. The solution was diluted withH₂O and the aqueous layer was washed with diethylether. The mixture wasacidified with 2N HCl aqueous soln., and extracted with ethyl acetate.The organic layer was washed with brine and dried with sodium sulfateand concentrated to give Compound 22a (10.6 g). Compounds 22b, 22c and22d were synthesized in accordance with the method shown in the aboveexamples.

22a: (DMSO-d6); 1.17 (d, J=6.8 Hz, 6H), 1.23 (s, 6H), 1.57-1.99 (m,14H), 4.03-4.05 (m, 1H), 4.27 (s, 2H), 8.40 (d, J=7.2 Hz, 1H),12.14-12.81 (brs, 1H)

22b: (DMSO-d6); 0.89 (t, J=7.2 Hz, 3H), 1.22 (s, 6H), 1.40-1.98 (m,16H), 2.78 (t, J=7.2 Hz, 2H), 4.01-4.08 (m, 1H), 4.27 (s, 2H), 8.36 (d,J=8.0 Hz, 1H)

22c: (DMSO-d6); 1.20 (d, J=6.8 Hz, 6H), 1.57-2.00 (m, 20H), 3.35-3.40(m, 1H), 4.30 (br, 1H), 8.44 (d, J=6.8 Hz, 1H), 13.09 (s, 3H)

22d: (DMSO-d6); 1.09 (s, 6H), 1.20 (d, J=6.4 Hz, 6H), 1.59 (d, J=12.4Hz, 2H), 1.72 (s, 2H), 1.82 (br, 6H), 1.94-2.00 (m, 4H), 2.31 (s, 2H),3.30 (br, 1H), 4.04 (br, 1H), 4.13 (s, 2H), 8.42 (d, J=6.8 Hz, 1H),12.11 (s, 1H)

To a solution of Compound 22a (10.6 g) in dimethylformamide (210 ml)were added tert-butyl-2-aminoethylcarbamate (4.66 g),1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (7.0 g) and1-hydroxybenzotriazole (1.64 g) under N₂ atmosphere, then the resultingsolution was stirred at room temperature for 10 hrs. After terminationof the reaction, the solution was poured into ice-cold water andextracted with ethyl acetate. The organic layer was washed with sat.sodium hydrogencarbonate soln. and brine successively, and dried withsodium sulfate. The residue was recrystallized from ethyl acetate-hexaneto give Compound 23a (13.3 g).

4N HCl/AcOEt (133 ml) was added to Compound 23a (13.3 g). The resultingsolution was stirred at room temperature for 2 hrs. After termination ofthe reaction, the solution was diluted with diisopropyl ether to givecrystal. The obtained crystal was collected by filtration and washedwith diisopropylether, then dried to give Compound 24a (11.5 g).

The above-mentioned examples are concerning Compound 22a and 24a.Compounds 22b˜22d and 24b˜24i were synthesized in accordance with themethod shown in the above examples.

TABLE 3 No. R² m n NMR 24a i-Pr 1 0 (DMSO-d6); 1.17 (d, J = 6.8 Hz, 6H),1.22 (s, 6H), 1.58-1.98 (m, 14H), 2.70-2.76 (m, 2H), 3.20-3.80 (m, 4H),4.03-4.08 (m, 1H), 4.27 (s, 2H), 7.86-7.89 (m, 1H), 8.40 (d, J = 7.2 Hz,1H) 24b i-Pr 1 0 (DMSO-d6); 1.17 (d, J = 6.8 Hz, 6H), 1.221(s, 6H),1.58-1.98 (m, 18H), 2.87-2.93 (m, 2H), 3.22-3.81 (m, 5H), 4.02-4.05 (m,1H), 4.30 (s, 2H), 7.69 (d, J = 7.2 Hz, 1H), 8.39 (d, J = 7.6 Hz, 1H)24c i-Pr 1 0 (DMSO-d6); 1.16 (d, J = 6.8 Hz, 6H), 1.23 (s, 6H),1.58-1.98 (m, 14H), 3.71 (d, J = 5.6 Hz, 2H), 4.03-4.05 (m, 1H), 4.28(s, 2H), 7.98-8.06 (m, 1H), 8.39 (d, J = 7.2 Hz, 1H) 24d i-Pr 1 0(DMSO-d6); 1.17 (d, J = 6.8 Hz, 6H), 1.26-1.34 (m, 8H), 1.58-1.96 (m,16H), 2.84-4.04 (m, 8H), 4.22-4.29 (m, 3H), 8.40 (d, J = 7.2 Hz, 1H) 24en-Pr 1 0 (DMSO-d6); 0.88 (t, J = 7.2 Hz, 3H), 1.23 (s, 6H), 1.39-1.98(m, 16H), 2.77 (t, J = 7.2 Hz, 2H), 3.72(d, J = 5.6 Hz, 2H), 4.01-4.03(m, 1H), 4.27 (s, 2H), 8.04 (m, 1H), 8.33 (d, J = 6.8 Hz, 1H) 24f n-Pr 10 (DMSO-d6); 0.88 (t, J = 7.2 Hz, 3H), 1.22 (s, 6H), 1.44-1.97 (m, 16H),2.75-2.79 (m, 2H), 3.22-4.01 (m, 7H), 4.26 (s, 2H), 7.84-7.86 (m, 1H),8.34 (d, J = 7.6 Hz, 1H) 24g n-Pr 1 0 (DMSO-d6); 0.89 (t, J = 7.2 Hz,3H), 1.21 (s, 6H), 1.42-2.00 (m, 20H), 2.76-3.81 (m, 8H), 4.03 (d, J =6.8 Hz, 1H), 4.30 (s, 2H), 7.66 (d, J = 7.2 Hz, 1H), 8.35 (d, J = 6.8Hz, 1H) 24h n-Pr 1 0 (DMSO-d6); 0.89 (t, J = 7.2 Hz, 3H), 1.34-2.00 (m,29H), 2.77-2.92 (m, 3H), 4.01-4.03 (m, 1H), 4.28-4.31 (m, 3H), 8.15(brs, 2H), 8.37 (d, J = 7.2 Hz, 1H) 24i i-Pr 0 0 (DMSO-d6); 1.21 (d, J =6.8 Hz, 6H), 1.58-1.99 (m, 20H), 2.57 (br, 2H), 3.06-3.10 (m, 2H),3.40-3.46 (m, 1H), 4.04 (br, 1H), 7.75 (br, 1H), 8.43 (d, J = 7.6 Hz,1H)

EXAMPLE 4

Compound 22a (200 mg) was dissolved in toluene (2 ml) and dioxane (1ml), and then diphenylphosphoryl azide (103 μl) was added to theresulting solution. The solution was stirred at 120° C. for 5 hrs. Aftertermination of the reaction, the solution was diluted with ethylacetate. The resulting mixture was washed with 1N HCl aqueous soln.,sat. sodium hydrogencarbonate soln. and brine successively, and driedwith sodium sulfate and concentrated to give Compound 25 (140 mg).

To a solution of Compound 25 (60 mg) in dioxane (0.6 ml) was addedtert-butyl-2-aminoethylcarbamate (45 mg), then the resulting solutionwas stirred at room temperature for 2 hrs. After termination of thereaction, 2N HCl aqueous soln. was added to the solution, then extractedwith ethyl acetate. The organic layer was washed with sat. sodiumhydrogencarbonate soln. and brine successively, and dried with sodiumsulfate and concentrated. Diethylether was added to the residue, and theresulting powder was collected by filtration and dried to give Compound26 (81 mg).

4N HCl/dioxane (0.8 ml) was added to Compound 26 (79 mg), then theresulting solution was stirred at room temperature for 1.5 hrs. Aftertermination of the reaction, the solution was diluted with H₂O andwashed with diethylether. The aqueous layer was alkalified with 2N NaOHaqueous soln., and extracted with ethyl acetate. The organic layer waswashed with brine and dried with magnesium sulfate and concentrated. Theresidue was purified by silicagel columnchromatography to give Compound27 (46 mg).

Compound 28 was synthesized by using Compound 25 andtert-butyl-2-hydroxyethylcarbamate in accordance with the method shownin the above Examples.

TABLE 4 No. NMR 27 (CDCl3); 1.29 (d, J = 6.8 Hz, 6H), 1.42 (s, 6H),1.70-2.04 (m, 14H), 2.84 (br, 2H), 3.22 (br, 2H), 3.38-3.44 (m, 1H),4.25 (br, 1H), 4.43 (s, 2H), 5.43 (s, 1H), 5.48 (br, 1H), 8.13 (d, J =8.0 Hz, 1H) 28 (DMSO-d6); 1.19 (d, J = 6.8 Hz, 6H), 1.29 (s, 6H), 1.59(d, J = 12.4 Hz, 2H), 1.72 (s, 2H), 1.82 (br, 6H), 1.93-1.99 (m, 4H),2.67 (t, J = 6.0 Hz, 2H), 3.33-3.38 (m, 1H), 3.82 (t, J = 6.0 Hz, 2H),4.03 (br, 1H), 4.33 (s, 2H), 7.11 (s, 1H), 8.41 (d, J = 7.6 Hz, 2H)

EXAMPLE 5

4N HCl/dioxane (4.2 ml) was added to Compound 25 (210 mg), then theresulting solution was stirred at room temperature for 7 hrs. Aftertermination of the reaction, diethylether was added to the solution, andthe obtained white precipitate was collected by filtration and washedwith diethylether, then dried to give Compound 29 (135 mg).

To a solution of Compound 29 (50 mg) in dimethylformamide (1 ml) wereadded N-Boc-β-alanine (26 mg),1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (33 mg) and1-hydroxybenzotriazole (8 mg), then triethylamine (43 μl) was addeddropwisely to the solution. The resulting solution was stirred at roomtemperature for 9 hrs. After termination of the reaction, 2N HCl aqueoussoln. (400 ml) was added to the solution, then extracted with ethylacetate. The extraction was washed with sat. sodium hydrogencarbonatesoln. and brine successively, then dried with sodium sulfate andconcentrated. The residue was purified by silicagel columnchromatographyto give Compound 30 (62 mg).

4N HCl/dioxane (1.2 ml) was added to Compound 30 (62 mg), then theresulting solution was stirred at room temperature for 2 hrs. Aftertermination of the reaction, the solution was diluted with H₂O andwashed with diisopropylether. The aqueous layer was alkalified with 2NNaOH aqueous soln., and extracted with ethyl acetate. The organic layerwas washed with brine and dried with sodium sulfate and concentrated.The residue was purified by silicagel columnchromatography to giveCompound 31 (35 mg).

TABLE 5 No. NMR 29 (DMSO-d6); 1.20 (d, J = 6.8 Hz, 6H), 1.39 (s, 6H),1.60 (d, J = 11.6 Hz, 2H), 1.72 (s, 2H), 1.83 (br, 6H), 1.94-2.00 (m,4H), 3.41-3.49 (m, 1H), 4.04 (br, 1H), 4.35 (s, 2H), 8.46 (d, J = 7.2Hz, 1H), 8.56 (brs, 3H) 31 (DMSO-d6); 1.20 (d, J = 5.6 Hz, 6H), 1.32 (s,6H), 1.59 (d, J = 12.4 Hz, 2H), 1.72 (s, 2H), 1.82 (br, 6H), 1.93-1.99(m, 4H), 2.13 (br, 2H), 2.70 (br, 2H), 3.31-3.40 (m, 1H), 4.03 (br, 1H),4.41 (s, 2H), 7.81 (s, 1H), 8.40 (m, 1H)

The following compounds were synthesized as well as the above-mentionedexecution example 1˜5.

Liquid chromatography mass spectrometry (LC-MS) made of Waters was usedfor the measurement of molecular weight. The column made of PhenomenexLuna 5 μC18 (2)100 A (50 mm×4.60 mmΦ) was used for the measurement. Theelution was a straight line inclination of MeCN density (10%˜100%/3 min)at flow velocity 3.0 mL/min.

TABLE 6 retention No. Structure NMR time MS II-1

(DMSO-d6); 0.91 (d, J = 6.4 Hz, 6H), 1.24 (s, 6H), 1.55-2.02 (m, 15H),2.71 (d, J = 6.8 Hz, 2H), 4.02 (brs, 1H), 4.28 (s, 2H), 8.37 (d, J = 7.2Hz, 1H), 12.53 (s, 1H) II-2

(DMSO-d6); 0.91 (d, J = 6.0 Hz, 6H), 1.21 (s, 6H), 1.55-2.01 (m, 15H),2.57 (brs, 2H), 2.71 (d, J = 6.0 Hz, 2H), 3.07 (brs, 2H), 4.02 (brs,1H), 4.27 (s, 2H), 7.66 (brs, 1H), 8.35 (d, J = 5.6 Hz, 1H) II-3

(DMSO-d6); 1.19 (d, J = 6.4 Hz, 6H), 1.24 (s, 6H), 1.30 (s, 6H),1.58-1.99 (m, 14H), 3.07 (brs, 2H), , 3.30-3.40 (m, 1H), 4.03 (brs, 1H),4.31 (s, 2H), 7.10 (s, 1H), 8.09 (brs, 3H), 8.41 (d, J = 6.4 Hz, 1H)II-4

(DMSO-d6); 1.13 (s, 6H), 1.22 (d, J = 6.4 Hz, 6H), 1.59-1.99 (m, 14H),2.89 (brs, 2H), , 3.13 (brs, 2H), 3.18 (brs, 2H), 3.30-3.40 (m, 1H),4.04 (brs, 1H), 4.17 (s, 2H), 8.43 (d, J = 8.4 Hz, 1H) II-5

2.43 507.9 II-6

2.26 522.4 II-7

2.35 508.4

TABLE 7 retention No. Structure NMR time MS II-8 

2.45 523.1 II-9 

2.25 508.4 II-10

2.46 547.9 II-11

2.53 548.4 II-12

2.57 576.4 II-13

2.540 547.9 II-14

2.03 564.9

TABLE 8 retention No. Structure NMR time MS II-15

1.54 520.5 II-16

1.52 534.5 II-17

1.52 534.3 II-18

1.49 505.6 II-19

1.50 520.5 II-20

1.46 494.3 II-21

1.48 506.5

TABLE 9 reten- tion No. Structure NMR time MS II-22

1.49 506.3 II-23

1.48 494.5 II-24

1.56 560.2 II-25

(DMSO-d6); 1.19(d, J = 6.4 Hz, 6H), 1.53- 2.02(m, 14H), 2.88-2.98(m,2H), 3.25- 3.37(m, 1H), 3.40-3.50(m, 2H), 4.00- 4.08(m, 1H), 4.89(t, J =13.6 Hz, 2H), 8.14- 8.24(br, 2H), 8.47(d, J = 7.2 Hz, 1H), 9.25-9.31(br, 1H) II-26

(DMSO-d6); 0.76(t, J = 6.4 Hz, 6H), 1.17(d, J = 6.4 Hz, 6H),1.49-2.03(m, 18H), 2.52-2.63(m, 2H), 2.91-3.52(m, 3H), 3.97-4.07(m, 1H),4.33(s, 2H), 7.65- 7.72(br, 1H), 8.41 (d, J = 6.4 Hz, 1H) II-27

hydrochloride (DMSO-d6); 1.06 (s, 6H), 1.20 (d, J = 6.4 Hz, 6H),1.58-2.00 (m, 14H), 2.20 (s, 2H), 2.83 (brs, 2H), 3.27-3.40 (m, 3H),4.04 (brs, 1H), 4.15 (s, 2H), 8.09 (brs, 3H), 8.31 (brs, 1H), 8.44 (d, J= 7.2 Hz, 1H) II-28

(DMSO-d6); 0.92 (s, 6H), 1.20 (d, J = 6.4 Hz, 6H), 1.58-1.99 (m, 14H),2.48 (s, 2H), 3.32-3.36 (, m, 1H), 4.05 (brs, 3H), 8.40 (d, J = 6.8 Hz,1H)

TABLE 10 reten- tion No. Structure NMR time MS II-29

(DMSO-d6) 1.16-1.22(m, 14H), 1.58- 1.99(m, 14H), 3.33-3.42(m, 1H), 4.01-4.07(m, 1H), 4.27(s, 2H), 4.50-4.55(m, 1H), 6.89(brs, 1H), 7.35(brs,1H), 7.88(d, J = 6.8 Hz, 1H), 8.39(d, J = 5.6 Hz, 1H) II-30

(DMSO-d6) 1.09-1.23(m, 14H), 1.58- 2.13(m, 16H), 3.33-3.42(m, 1H), 4.00-4.05(m, 1H), 4.13-4.20(m, 1H), 4.29(s, 2H), 6.80(brs, 1H), 7.23(brs,1H), 7.93- 7.94(m, 1H), 8.37-8.40(m, 1H) II-31

(DMSO-d6) 1.09-1.24(m, 14H), 1.58- 2.13(m, 16H), 3.33-3.42(m, 1H), 4.02-4.05(m, 1H), 4.13-4.20(m, 1H), 4.29(s, 2H), 6.80(brs, 1H), 7.29(brs,1H), 7.93- 7.95(m, 1H), 8.36-8.41(m, 1H) II-32

1.53 576.4 II-33

2.43 548.6 II-34

2.38 536 II-35

2.41 522

TABLE 11 retention No. Structure NMR time MS II-36

2.37 505.9 II-37

2.37 505.9 II-38

2.34 508 II-39

2.41 536 II-40

1.49 466.2 II-41

1.45 480.3 II-42

1.46 494.3

TABLE 12 retention No. Structure NMR time MS II-43

1.52 480.4 II-44

1.48 537 II-45

1.65 556.5 II-46

1.67 594.6 II-47

1.56 508.4 II-48

1.54 507 II-49

1.56 491

TABLE 13 reten- tion No. Structure NMR time MS II-50

1.54 541.6 II-51

1.54 519.1 II-52

(CD3OD); 1.28 (d, J = 6.8 Hz, 6H), 1.42 (s, 6H), 1.74-2.01 (m, 14H),3.17 (brs, 2H), 3.38-3.44 (m, 1H), 3.62 (brs, 2H), 4.14 (s, 2H), 4.20 (,s, 1H), 4.39 (s, 2H), 8.46 (d, J = 5.6 Hz, 1H) II-53

(DMSO-d6); 0.90 (d, J = 6.4 Hz, 6H), 1.25 (s, 6H), 1.56-2.05 (m, 15H),2.70 (d, J = 6.8 Hz, 2H), 3.73 (d, J = 5.6 Hz, 2H), 4.03 (d, J = 6.4 Hz,1H), 4.28 (s, 2H), 8.05 (brs, 1H), 8.35 (d, J = 7.2 Hz, 1H) II-54

(DMSO-d6); 0.99 (s, 6H), 1.21 (d, J = 6.4 Hz, 6H), 1.36 (brs, 2H),1.50-1.99 (m, 16H), 2.74 (brs, 2H), 3.30-3.36 (, m, 1H), 4.00 (s, 2H),4.04 (brs, 1H), 7.83 (brs, 3H), 8.42 (d, J = 7.2 Hz, 1H) II-55

(DMSO-d6) 1.16-1.24(m, 10H), 1.59- 2.21(m, 14H), 2.90-2.92(m, 1H), 3.32-3.44(m, 4H), 4.03-4.05(m, 1H), 4.39(s, 2H), 7.36(brs, 1H), 7.60(brs,1H), 8.39- 8.41(m, 1H), 8.56-8.62(m, 1H) II-56

(DMSO-d6) 1.17-1.20(m, 12H), 1.31- 2.06(m, 13H), 3.33-3.42(m, 1H), 3.89-3.93(m, 1H), 4.25(s, 2H), 4.47(s, 1H), 6.97(brs, 1H), 7.23(brs, 1H),8.34- 8.36(m, 1H)

TABLE 14 reten- tion No. Structure NMR time MS II-57

(DMSO-d6) 1.17(d, J = 6.8 Hz, 6H), 1.33(s, 6H), 1.40-2.10(m, 13H), 3.33-3.42(m, 1H), 3.52-3.58(m, 8H), 3.90- 4.03(m, 1H), 4.32(s, 2H), 4.47(s,1H), 8.36(d, J = 7.2 Hz, 1H) II-58

(DMSO-d6) 1.01-1.22(m, 12H), 1.39- 2.04(m, 13H), 2.70-2.77(m, 2H), 3.33-3.42(m, 4H), 3.87-3.94(m, 1H), 4.27(s, 2H), 4.44-4.50(m, 1H),7.86-7.91(m, 1H), 8.30-8.38(m, 1H) II-59

(DMSO-d6); 1.03(s, 3H), 1.05(s, 3H), 1.20(d, J = 6.9 Hz, 6H),1.58-2.00(m, 14H), 3.10- 3.23(m, 2H)3.35-3.44(m, 2H), 3.54- 3.64(m, 1H),4.03- 4.05(m, 1H), 4.23(s, 2H), 7.57(s, 1H), 8.13(bs, 2H), 8.44(d, J =7.2 Hz, 1H) II-60

(DMSO-d6); 1.17-2.00 (m, 30H), 2.71 (brs, 1H), 2.97 (brs, 1H), 3.33-3.41(, m, 1H), 3.57-3.70 (brm, 2H), 4.03 (brs, 1H), 4.21 (brs, 1H), 4.31 (d,J = 10 Hz, 1H), 4.38 (d, J = 10 Hz, 1H), 8.14 (brs, 3H), 8.41 (d, J =6.4 Hz, 1H) II-61

(DMSO-d6) 1.17(d, J = 6.8 Hz, 6H), 1.40-2.22(m, 17H), 3.33-3.42(m, 1H),3.44(t, J = 6.8 Hz, 2H), 3.60-3.63(m, 2H), 3.94-3.98(m, 1H),4.38-4.42(m, 2H), 4.47(s, 1H), 8.36(d, J = 7.6 Hz, 1H) II-62

(DMSO-d6) 0.81-1.76(m, 23H), 2.80- 2.85(m, 2H), 3.33-3.42(m, 3H), 3.88-3.94(m, 1H), 4.23(s, 1H), 7.72-8.05(m, 4H) II-63

(DMSO-d6) 1.19(d, J = 6.4 Hz, 6H), 1.40-2.07(m, 13H), 2.93-3.37(m, 5H),3.94-3.98(m, 1H), 4.23(s, 1H), 8.37(d, J = 7.2 Hz, 1H)

TABLE 15 retention No. Structure NMR time MS II-64

(DMSO-d6) 1.16(d, J = 6.4 Hz, 6H), 1.57-2.44(m, 20H), 3.28-3.33(m, 1H),4.01-4.06(m, 1H), 4.52(s, 2H), 8.39(d, J = 6.8 Hz, 1H), 12.55(brs, 1H)II-65

(DMSO-d6) 1.18(d, J = 6.8 Hz, 6H), 1.40-1.2.07(m, 13H), 2.96(s, 3H),3.37- 3.44(m, 3H), 3.93-3.97(m, 1H), 4.31- 4.36(m, 2H), 4.47(s, 1H),7.29-7.35(m, 1H), 8.38(d, J = 6.8 Hz, 1H) II-66

(DMSO-d6) 1.17(d, J = 6.4 Hz, 6H), 1.58-2.39(m, 20H), 3.28-3.33(m, 1H),4.01-4.06(m, 1H), 4.51(s, 2H), 7.01(brs, 1H), 7.28(brs, 1H), 8.39(d, J =7.2 Hz, 1H) II-67

(DMSO-d6); 0.9(d, J = 6.9 Hz, 6H), 1.51- 2.06(m, 14H), 2.70(d, J = 6.9Hz, 2H), 2.81- 2.89(m, 2H), 4.03(m, 1H), 4.88(t, J = 12.9 Hz, 2H),8.46(m, 1H)

TABLE 16 No. Structure NMR II-68

(DMSO-d6); 1.16(d, J = 6.6 Hz, 6H), 1.57-2.06(m. 18H), 2.34-2.48(m, 2H),2.81-2.89(m, 2H), 3.25-3.38(m, 2H), 4.00-4.07(m, 1H), 4.53(s, 2H), 8.01(br.s, 2H), 8.12(m, 1H), 8.42(d, J = 7.2 Hz, 1H) II-69

(DMSO-d6); 1.20(d, J = 6.0 Hz, 6H), 1.33(s, 6H), 1.53- 2.04(m, 16H),2.16-2.42(m, 2H), 3.30-3.43(m, 1H), 3.78-3.88(m, 1H), 3.99-4.07(m, 1H),4.41(s, 2H), 7.91- 7.96(br, 1H), 8.41(d, J = 6.4 Hz, 1H), 8.46-8.55(br,2H) II-70

(DMSO-d6); 1.21(d, J = 6.0 Hz, 6H), 1.37(s, 6H), 1.53- 2.03(m, 17H),3.31-3.46(m, 1H), 3.69-3.88(m, 3H), 3.99-4.08(m, 1H), 4.34-4.50(m, 2H),5.41-5.66(br, 1H), 8.41(d, J = 6.8 Hz, 1H), 8.60-8.66(br, 1H), 8.77-8.91(br, 1H), 9.20-9.32(br, 1H) II-71

(DMSO-d6); 0.90 (d, J = 6.4 Hz, 6H), 1.55-2.10 (m, 19H), 2.38 (brs, 2H),2.69 (d, J = 6.4 Hz, 2H), 4.02 (brs, 1H), 4.52 (s, 2H), 8.36 (d, J = 6.4Hz, 1H), 12.55 (brs, 1H) II-72

(DMSO-d6): 0.93 (d, J = 4.4 Hz, 6H), 0.99 (s, 6H), 1.36 (brs, 2H),1.55-2.01 (m, 17H), 2.75 (brs, 4H), 3.97-4.04 (brm, 3H), 8.03 (brs, 3H),8.38 (d, J = 4.8 Hz, 1H) II-73

(DMSO-d6); 0.90 (d, J = 6.0 Hz, 6H), 1.55-2.05 (m, 19H), 2.43 (brs, 2H),2.70 (d, J = 6.4 Hz, 2H), 2.85 (brs, 2H), 3.35 (brs, 2H), 4.02 (brs,1H), 4.54 (s, 2H), 8.16 (brs, 3H), 8.35 (d, J = 6.8 Hz, 1H) II-74

(DMSO-d6); 0.90(t, J = 7.2 Hz, 3H), 0.97(s,, 6H), 1.34- 1.99(m, 20H),2.68- 2.80(m, 2H)2,82(t, J = 7.2 Hz, 2H)3.99(s, 2H), 3.99- 4.03(m,1H)7.80(bs, 2H), 8.37(d, J = 7.2 Hz, 1H)

TABLE 17 No. Structure NMR II-75

(CDCl3); 0.99(t, J= 7.2 Hz, 3H), 1.13(d, J = 7.2 Hz, 2H), 1.46(s,, 6H),1.53-2.08(m, 20H), 2.40-2.49(m, 2H), 2.58- 2.66(m, 2H), 2.85(t, J = 7.2Hz, 2H), 3.63- 3.67(m, 1H), 4.24- 4.27(m, 1H), 4.44(s, 2H), 6.15(s, 1H),7.95(d, J = 8.4 Hz, 1H) II-76

(DMSO-d6); 0.9(d, J = 6.9 Hz, 6H), 1.54-2.03(m. 14H), 2.71(t, J = 3.3Hz, 2H), 2.89-2.94(m, 2H), 4.90(t, J = 13.5 Hz, 2H), 8.14(br-s, 1H),8.46(m, 1H), 8.46(d, J = 7.2 Hz, 1H), 9.28(s, 1H) II-77

(DMSO-d6); 0.93 (d, J = 6.4 Hz, 6H), 1.09 (s, 6H), 1.56-2.02 (m, 15H),2.75 (d, J = 6.8 Hz, 2H), 2.83 (brs, 2H), 4.03 (brs, 1H), 4.14 (s, 2H),8.22 (brs, 3H), 8.40 (d, J = 7.2 Hz, 1H) II-78

(DMSO-d6): 0.93 (d, J = 6.4 Hz, 6H), 1.57-2.07 (m, 17H), 2.21 (brs, 2H),2.33-2.42 (m, 2H), 2.79 (d, J = 6.8 Hz, 2H), 4.04 (brs, 1H), 4.52 (s,2H), 2.79 (d, J = 6.4 Hz, 1H), 8.67 (brs, 3H) II-79

(DMSO-d6); 1.04 (s, 6H), 1.21 (d, J = 6.4 Hz, 6H), 1.58-1.99 (m, 14H),3.00 (s, 3H),, 3.09 (brs, 2H), 3.17 (s, 2H), 3.37-3.47 (,m, 3H), 4.06(brs, 3H), 8.19 (brs, 3H), 8.41 (d, J = 7.2 Hz, 1H) II-80

(DMSO-d6) 0.99-1.99(m, 25H), 2.71-2.77(m, 2H), 3.28-3.33(m, 1H),3.52-3.60(m, 2H), 4.01-4.06(m, 7.72-7.87(m, 3H), 8.41-8.44(m, 1H) II-81

(DMSO-d6) 0.92(t, J = 7.4 Hz, 3H), 1.16(s, 6H), 1.40-2.05(m, 16H),2.83(t, J = 7.2 Hz, 2H), 2.95- 3.05(m, 2H), 3.20-3.30(m, 4H), 4.02(m,1H), 4.18(s, 2H), 8.32(m, 2H), 8.41(d, J = 7.2 Hz, 1H), 9.06(m, 1H)

TABLE 18 No. Structure NMR II-82

(DMSO-d6); 1.15-1.19(m, 12H), 1.56-1.99(m, 14H), 3.09-3.15(m, 2H),3.28-3.33(m, 3H), 4.26(s, 1H), 4.83(t, J = 5.4 Hz, 1H), 7.65(m, 1H),8.41(d, J = 7.5 Hz, 1H) II-83

(DMSO-d6); 1.19(d, J = 7.5 Hz, 6H), 1.54-2.03(m, 16H), 3.3-3.33(m, 1H),3.51-3.57(m, 2H), 4.04(m, 1H), 4.35(t, J = 6.6 Hz, 2H), 4.61(m, 1H),8.44(d, J = 7.2 Hz, 1H) II-84

(DMSO-d6); 1.02(s, 6H), 1.20(d, J = 6.6 Hz, 6H), 1.62- 2.01(m, 14H),3.4(m, 1H), 3.47(s, 2H), 4.19(s, 2H), 4.30(m, 1H), 8.09(m, 1H) II-85

(DMSO-d6); 1.29(d, J = 6.6 Hz, 6H), 1.69-2.02(m, 20H), 3.37(q, J = 6.9Hz, 1H), 3.69(s, 2H), 4.29(m, 1H), 4.44(s, 1H), 8.10(m, 1H) II-86

(DMSO-d6) 0.87-2.01(m, 19H), 2.76-2.80(m, 2H), 3.40-4.10(m, 5H),4.81-4.93(m, 2H), 8.06-8.31(m, 3H), 8.43(d, J = 6.8 Hz, 1H) II-87

(DMSO-d6) 0.75-2.01(m, 29H), 2.76-2.79(m, 2H), 3.11-3.53(m, 3H),4.02-4.08(m, 1H), 4.34(s, 2H), 7.72-7.79(m, 3H), 8.37-8.38(m, 1H) II-88

(DMSO-d6); 0.83 (t, J = 7.2 Hz, 6H), 0.91 (d, J = 6.4 Hz, 6H), 1.55-2.02(m, 19H), 2.70 (d, J = 6.8 Hz, 2H), 4.03 (d, J = 6.8 Hz, 1H), 4.34 (s,2H), 8.38 (d, J = 6.8 Hz, 1H), 12.68 (s, 1H)

TABLE 19 No. Structure NMR II-89

(DMSO-d6); 0.92 (d, J = 6.4 Hz, 6H), 1.55-2.20 (m, 21H), 2.29-2.33 (m,2H), 2.37-2.40 (m, 2H), 2.75 (d, J = 6.8 Hz, 2H), 4.03 (brd, J = 6.8 Hz,1H), 4.45 (s, 2H), 8.16 (s, 1H), 8.37 (d, J = 7.2 Hz, 1H), 12.02 (s, 1H)II-90

(DMSO-d6); 0.93 (d, J = 6.8 Hz, 6H), 1.39 (s, 6H), 1.56-2.02 (m, 15H),2.79 (d, J = 6.4 Hz, 2H), 4.03 (brs, 1H), 4.35 (s, 2H), 8.43 (d, J = 6.8Hz, 1H), 8.57 (brs, 3H) II-91

(DMSO-d6); 0.94 (d, J = 6.8 Hz, 6H), 1.18 (s, 6H), 1.56-2.02 (m, 15H),2.77 (d, J = 6.8 Hz, 2H), 3.01 (brs, 2H), 3.24-3.33 (brm, 4H), 4.03(brs, 1H), 4.20 (s, 2H), 8.40 (d, J = 7.2 Hz, 1H), 8.49 (brs, 3H), 9.31(brs, 2H) II-92

(DMSO-d6); 0.89-0.96 (brm, 6H), 1.32 (s, 6H), 1.55- 2.03 (m, 15H),2.27-2.40 (brm, 4H), 2.75 (brs, 2H), 4.03 (brs, 1H), 4.38 (s, 2H), 7.72(s, 1H), 8.39 (brs, 1H), 12.02 (s, 1H) II-93

(DMSO-d6); 0.77 (t, J = 6.0 Hz, 6H), 0.91 (d, J = 6.4 Hz, 6H), 1.55-2.02(m, 19H), 2.70 (d, J = 6.8 Hz, 2H), 2.84 (brs, 2H), 4.02 (brs, 1H), 4.36(s, 2H), 8.14 (brs, 3H), 8.21 (brs, 1H), 8.40 (d, J = 6.8 Hz, 1H) II-94

(DMSO-d6); 0.74(d, J = 6.9 Hz, 6H), 0.89(s, 6H), 1.38- 1.85(m, 15H),2.02(s, 2H), 2.58(d, J = 6.6 Hz, 2H), 2.66(t, J = 6.6 Hz, 2H),3.08-3.14(m, 2H), 3.82- 3.89(m, 1H), 3.98(s, 2H), 7.77(br.s, 2H),8.06(t, J = 5.7 Hz, 1H), 8.23(d, J = 6.9 Hz, 1H) II-95

(DMSO-d6); 1.19(d, J = 7.5 Hz, 6H), 1.54-2.03(m, 16H), 2.04(s, 3H),3.3-3.33(m, 1H), 3.51-3.57(m, 2H), 4.04(m, 1H), 4.35(t, J = 6.6 Hz, 2H),4.61 (m, 1H), 8.44(d, J = 7.2 Hz, 1H)

TABLE 20 No. Structure NMR II-96 

(DMSO-d6); 1.05(s, 9H), 1.31 (d, J = 6.9 Hz, 6H), 1.74-2.02(m, 14H),3.43(q, J = 6.9 Hz, 1H), 4.0(s, 2H), 4.31(m, 1H), 8.12(m, 1H) II-97 

(DMSO-d6); 1.23-1.35(m, 12H), 1.70-2.05(m, 14H), 3.41 (q, J = 6.6 Hz,1H), 4.21 (s, 2H), 4.28(m, 1H), 8.11(m, 1H) II-98 

(DMSO-d6); 1.18-2.02 (m, 30H), 2.45 (s, 2H), 2.83 (t, J = 6.6 Hz, 2H),3.14 (brs, 1H), 3.24-3.32 (m, 2H), 4.04 (brs, 1H), 4.34 (s, 2H), 7.89(brs, 3H), 8.22 (t, J = 6.0 Hz, 1H), 8.42 (d, J = 7.2 Hz, 1H) II-99 

(DMSO-d6); 1.10-2.02 (m, 30H), 2.57 (s, 2H), 3.11 (brs, 1H), 4.04 (brs,1H), 4.34 (s, 2H), 8.42 (d, J = 7.2 Hz, 1H), 12.18 (s, 1H) II-100

(CDCl3); 1.17-1.30 (m, 2H), 1.35 (s, 6H), 1.43-2.05 (m, 21H), 2.88 (d, J= 7.2 Hz, 2H), 3.23 (br, 2H), 3.66 (br, 2H), 4.21-4.24 (m, 1H), 4.43 (s,2H), 7.86 (br, 1H), 8.07-8.10 (m, 1H), 8.23 (br, 2H) II-101

(DMSO-d6); 1.17-1.19(m, 12H), 1.54-2.03(m, 17H), 2.80-2.92(m, 2H),3.25-3.35(m, 2H), 4.01-4.06(m, 1H), 4.26(t, J = 7.2 Hz, 2H), 7.89(t, J =5.7 Hz, 1H), 7.97(br.s, 2H), 8.43(d, J = 7.2 Hz, 1H) II-102

(CDCl3); 0.93-1.10 (m, 3H), 1.15 (s, 6H), 1.28-1.82 (m, 20H), 2.65 (d, J= 7.2 Hz, 2H), 4.05-4.08 (m, 1H), 4.16 (s, 2H), 7.70-7.73 (m, 1H)

TABLE 21 No. Structure NMR II-103

(CDCl3); 0.92-1.10 (m, 3H), 1.13 (s, 6H), 1.28-1.84 (m, 20H), 2.67 (d, J= 7.5 Hz, 2H), 4.04-4.08 (m, 1H), 4.14 (s, 2H), 5.32 (br, 1H), 5.74 (br,1H), 7.64- 7.68 (m, 1H) II-104

(DMSO-d6); 1.30(d, J = 6.6 Hz, 6H), 1.74-2.02(m, 14H), 2.09(s, 3H), 3.41(q, J = 6.6 Hz, 1H), 4.28(m, 1H), 4.45- 4.48(m, 2H), 4.54-4.58(m, 2H),8.11 (m, 1H) II-105

(DMSO-d6); 1.26-1.31(m, 6H), 1.71-2.02(m, 14H), 3.42(q, J = 6.6 Hz, 1H),3.99-4.03(m, 2H), 4.29(m, 1H), 4.49(m, 2H), 8.11(m, 1H) II-106

(DMSO-d6); 1.03(s, 6H), 1.31 (d, J = 6.6 Hz, 6H), 1.58- 2.02(m, 10H),2.20-2.29(m, 2H), 3.41 (q, J = 6.6 Hz, 1H), 3.47(s, 2H), 4.19(s, 2H),4.26(m, 1H), 7.99(m, 1H) II-107

(DMSO-d6); 1.19(d, J = 7.5 Hz, 6H), 1.54-2.03(m, 16H), 3.12(s, 3H),3.3-3.33(m, 1H), 3.51-3.57(m, 2H), 4.04(m, 1H), 4.35(t, J = 6.6 Hz, 2H),4.61 (m, 1H), 8.44(d, J = 7.2 Hz, 1H) II-108

(CDCl3); 1.17-1.27 (m, 2H), 1.32 (s, 6H), 1.50-2.05 (m, 21H), 2.82-2.88(m, 5H), 4.26-4.29 (m, 1H), 4.34 (s, 2H), 6.00-6.03 (m, 1H), 7.85-7.89(m, 1H) II-109

(CDCl3); 1.35 (s, 6H), 1.51-2.10 (m, 22H), 3.58 (m, 1H), 4.26-4.29 (m,1H), 4.35 (s, 2H), 5.59 (br, 1H), 6.02 (br, 1H), 8.03-8.08 (m, 1H)

TABLE 22 No. Structure NMR II-110

(CDCl3); 1.36 (s, 6H), 1.68-1.77 (m, 4H), 1.83-2.05 (m, 14H), 2.21-2.31(m, 2H), 3.75 (quintet, J = 9.0 Hz, 1H), 4.26-4.30 (m, 1H), 4.36 (s,2H), 8.06-8.10 (m, 1H) II-111

(DMSO-d6); 1.22 (s, 6H), 1.55-1.59 (m, 2H), 1.69- 1.98 (m, 16H),2.14-2.21 (m, 2H), 2.80-2.84 (m, 2H), 3.28-3.33 (m, 2H), 3.75 (quintet,J = 9.0 Hz, 1H), 3 99-4.04 (m, 1H), 4.26 (s, 2H), 8.02-8.11 (m, 3H),8.39-8.41(m, 1H) II-112

(CDCl3); 1.35 (s, 6H), 1.68-1.78 (m, 4H), 1.84-2.05 (m, 14H), 2.23-2.34(m, 2H), 3.76 (quintet, J = 9.0 Hz, 1H), 4.26-4.30 (m, 1H), 4.35 (s,2H), 5.61 (br, 1H), 6.02 (br, 1H), 8.03-8.05 (m, 1H) II-113

(DMSO-d6) 0.89(d, J = 6.8 Hz, 6H), 1.24-2.07(m, 20H), 2.68(d, J = 6.8Hz, 2H), 3.90-3.98(m, 1H), 4.34(s, 2H), 4.47(s, 1H), 6.90-6.96(m, 2H),8.33(d, J = 7.2 Hzm, 1H) II-114

(DMSO-d6) 0.90(d, J = 6.8 Hz, 6H), 1.05(d, J = 6.4 Hz, 6H), 1.19-2.07(m,20H), 2.70(d, J = 6.4 Hz, 2H), 3.83-3.96(m, 2H), 4.27(s, 2H), 4.49(s,1H), 7.38(d, J = 7.6 Hz, 1H), 8.32-8.34(m, 1H) II-115

(DMSO-d6) 0.40-0.62(m, 4H), 0.91(d, J = 6.4 Hz, 6H), 1.18(s, 6H),1.19-2.07(m, 14H), 2.59-2.73(m, 3H), 3.83-3.96(m, 1H), 4.25(s, 2H),4.49(s, 1H), 7.63-7.67(m, 1H), 8.31-8.34(m, 1H) II-116

(DMSO-d6) 0.90(d, J = 6.8 Hz, 6H), 1.00(t, J = 7.2 Hz, 3H), 1.20(s, 6H),1.24-2.07(m, 14H), 2.70(d, J = 6.8 Hz, 2H), 3.06-3.12(m, 2H),3.92-3.96(m, 1H), 4.26(s, 2H), 4.49(s, 1H), 7.69(t, J = 7.2 Hz, 1H),8.33(d, J = 7.2 Hz, 1H)

TABLE 23 No. Structure NMR II-117

(DMSO-d6); 1.03(s, 6H), 1.30(d, J = 6.9 Hz, 6H), 1.61- 2.02(m, 14H),3.23(s, 2H), 3.31(s, 3H), 3.41(q, J = 6.6 Hz, 1H), 4.12(s, 2H), 4.28(m,1H), 8.10(m, 1H) II-118

(DMSO-d6); 1.3-1.35(m, 12H), 1.60-1.92(m, 10H), 2.20-2.29(m, 3H), 3.41(q, J = 6.6 Hz, 1H), 4.20(s, 2H), 4.25(m, 1H), 8.00(m, 1H) II-119

(DMSO-d6); 1.2(d, J = 6.6 Hz, 6H), 1.43(s, 6H), 1.56- 2.01(m, 14H),3.37(q, J = 6.6 Hz, 1H), 4.04(m, 1H), 4.35(s, 2H), 8.10(m, 1H) II-120

(DMSO-d6); 1.29(d, J = 6.9 Hz, 6H), 1.57-2.01 (m, 16H), 2.05-2.14(m,3H), 3.38(q, J = 6.6 Hz, 1H), 3.69(s, 2H), 4.24(m, 1H), 4.43(s, 2H),7.97(m, 1H) II-121

(DMSO-d6) 1.17(d, J = 6.4 Hz, 6H), 1.23-1.99(m, 24H), 3.28-3.33(m, 1H),4.03(d, J = 5.6 Hz, 1H), 4.27(s, 2H), 7.00(brs, 1H), 7.25(brs, 1H),8.38(d, J = 7.2 Hz, 1H) II-122

(CDCl3); 1.18 (s, 6H), 1.31 (d, J = 6.0 Hz, 6H), 1.44- 1.46 (m, 2H),1.56-2.25 (m, 11H), 2.31 (s, 2H), 3.39- 3.45 (m, 1H), 3.65 (br, 1H),4.20 (s, 2H), 4.22-4.26 (m, 1H), 5.66-5.70 (m, 2H), 7.95-7.97 (m, 1H)II-123

(CDCl3); 1.28 (d, J = 6.0 Hz, 6H), 1.58-1.62 (m, 2H), 1.77-2.12 (m,12H), 2.21-2.23 (m, 3H), 2.48-2.57 (m, 2H), 3.33-3.42 (m, 1H), 4.24-4.26(m, 1H), 4.59 (s, 2H), 5.46 (br, 1H), 5.89 (br, 1H), 7.90-7.93 (m, 1H)

TABLE 24 No. Structure NMR II-124

(DMSO-d6); 0.77(t, J = 6.9 Hz, 2H), 0.97(t, J = 6.9 Hz, 2H), 1.32(d, J =6.6 Hz, 6H), 1.57-1.95(m, 10H), 2.0- 2.26(m, 3H), 3.44(q, J = 6.6 Hz,1H), 4.24(m, 1H), 4.43(s, 2H), 7.98(m, 1H) II-125

(DMSO-d6) 0.88-0.92(m, 2H), 1.11-1.19(m, 8H), 1.59-1.99(m, 14H),3.30-3.45(m, 1H), 4.04(d, J = 5.2 Hz, 1H), 4.40(s, 2H), 7.01 (brs, 1H),7.16(brs, 1H), 8.40(d, J = 7.2 Hz, 1H) II-126

(DMSO-d6) 1.14-2.08(m, 25H), 3.30-3.45(m, 1H), 3.94-3.97(m, 1H),4.10-4.26(m, 3H), 4.49(s, 1H), 7.76(d, J = 6.4 Hz, 1H), 8.31-8.35(m, 1H)II-127

(DMSO-d6) 1.16-2.08(m, 34H), 3.30-3.45(m, 1H), 3.90-3.97(m, 1H), 4.27(s,2H), 4.49(s, 1H), 6.77(s, 1H), 8.34(d, J = 7.2 Hz, 1H) II-128

(DMSO-d6) 1.14-2.06(m, 25H), 3.30-3.45(m, 4H), 3.90-3.97(m, 1H),4.33-4.50(m, 3H), 6.86-6.88(m, 1H), 8.33-8.36(m, 1H) II-129

(CDCl3); 1.33 (d, J = 6.0 Hz, 6H), 1.51 (s, 6H), 1.62- 1.87 (m, 8H),2.24-2.28 (m, 5H), 3.44-3.53 (m, 1H), 4.28 (s, 2H), 4.30-4.33 (m, 1H),8.01 (s, 1H), 8.04- 8.07 (m, 1H) II-130

(CDCl3); 1.33 (d, J = 6.0 Hz, 6H), 1.34 (s, 3H), 1.51 (s, 6H), 1.62-1.63(m, 2H), 1.77-1.85 (m, 6H), 1.91- 1.97 (m, 2H), 2.53 (br, 3H), 3.44-3.53(m, 1H), 4.24- 4.27 (m, 1H), 4.28 (s, 2H), 8.04-8.06 (m, 1H)

TABLE 25 No. Structure NMR II-131

(DMSO-d6) 1.17(d, J = 6.4 Hz, 6H), 1.57-2.03(m, 22H), 3.30-3.45(m, 1H),4.00-4.08(m, 1H), 4.35(s, 2H), 6.94(brs, 1H), 7.25(brs, 1H), 8.38(d, J =8.0 Hz, 1H) II-132

(DMSO-d6) 1.17(d, J = 6.0 Hz, 6H), 1.28(s, 6H), 1.39-2.06(m, 13H),3.30-3.57(m, 4H), 3.90-4.00(m, 1H), 4.33(s, 2H), 4.49(s, 1H),7.10-7.18(m, 1H), 8.27-8.39(m, 1H) II-133

(DMSO-d6) 1.19(d, J = 6.8 Hz, 6H), 1.28(s, 6H), 1.39-2.07(m, 13H),3.30-3.50(m, 1H), 3.90-4.00(m, 1H), 4.37(s, 2H), 4.49(s, 1H), 5.32(s,2H), 5.95(s, 1H), 8.36(d, J = 6.4 Hz, 1H) II-134

(DMSO-d6) 1.39-2.39(m, 27H), 3.56-3.60(m, 1H), 3.90-4.00(m, 1H), 4.47(s,1H), 4.52(s, 2H), 7.00(s, 1H), 7.29(s, 1H), 8.32(d, J = 7.2 Hz, 1H)II-135

(DMSO-d6) 1.20(s, 6H), 1.34-2.06(m, 21H), 3.57- 3.60(m, 1H),3.90-3.98(m, 1H), 4.26(s, 2H), 4.46(s, 1H), 6.97(s, 1H), 7.23(s, 1H),8.33(d, J = 6.8 Hz, 1H) II-136

(DMSO-d6) 1.20(d, J = 6.8 Hz, 6H), 1.36(s, 6H), 1.41-2.07(m, 13H),3.30-3.50(m, 1H), 3.90-3.98(m, 1H), 4.33(s, 2H), 4.49(s, 1H),8.14-8.30(m, 2H), 8.41(d, J = 6.8 Hz, 1H) II-137

(DMSO-d6); 0.97 (s, 6H), 1.38-1.42 (m, 2H), 1.62- 1.93 (m, 12H), 2.05(br, 3H), 2.18-2.25 (m, 2H), 3.20 (s, 2H), 3.25 (s, 3H), 3.79 (quintet,J = 9.0 Hz, 1H), 3.93-3.96 (m, 1H), 4.03 (s, 2H), 4.52 (s, 1H), 8.37-8.40(m, 1H)

TABLE 26 No. Structure NMR II-138

(DMSO-d6); 1.19 (s, 6H), 1.37-1.43 (m, 2H), 1.62- 1.89 (m, 12H), 2.05(br, 3H), 2.18-2.25 (m, 2H), 3.79 (quintet, J = 9.0 Hz, 1H), 3.93-3.95(m, 1H), 4.24 (s, 2H), 4.49 (s, 1H), 7.01 (s, 1H), 7.26 (s, 1H), 8.35-8.37(m, 1H) II-139

(DMSO-d6) 1.24-2.09(m, 21H), 3.59-3.70(m, 1H), 3.90-4.02(m, 1H),4.30-4.53(m, 3H), 8.35-8.46(m, 1H) II-140

(DMSO-d6) 1.06(s, 6H), 1.42-2.13(m, 23H), 3.55- 3.62(m, 1H),3.90-3.98(m, 1H), 4.16(s, 2H), 4.47(s, 1H), 6.77(brs, 1H), 7.29(brs,1H), 8.36(d, J = 6.4 Hz, 1H) II-141

(DMSO-d6); 1.43 (s, 6H), 1.37-1.45 (m, 2H), 1.62- 1.94 (m, 12H), 2.06(br, 3H), 2.21-2.29 (m, 2H), 3.83 (quintet, J = 9.0 Hz, 1H), 3.94-3.96(m, 1H), 4.34 (s, 2H), 4.49 (s, 1H), 8.40-8.42(m, 1H) II-142

(DMSO-d6) 1.28-2.06(m, 27H), 3.40-3.69(m, 4H), 3.90-3.98(m, 1H), 4.33(s,2H), 4.53(s, 1H), 7.09- 7.18(m, 1H), 8.34(d, J = 6.4 Hz, 1H) II-143

(DMSO-d6) 1.28(s, 6H), 1.39-2.06(m, 21H), 3.58- 3.64(m, 1H),3.90-3.98(m, 1H), 4.37(s, 2H), 4.51(s, 1H), 5.32(s, 2H), 5.97(s, 1H),8.34(d, J = 7.2 Hz, 1H) II-144

(DMSO-d6); 1.06 (s, 6H), 1.39-1.42 (m, 2H), 1.62- 1.92 (m, 12H), 2.06(br, 3H), 2.13 (s, 2H), 2.18-2.26 (m, 2H), 3.80 (quintet, J = 9.0 Hz,1H), 3.93-3.96 (m, 1H), 4.15 (s, 2H), 4.49 (s, 1H), 6.80 (s, 1H), 7.31(s, 1H), 8.37-8.40(m, 1H)

TABLE 27 No. Structure NMR II-145

(DMSO-d6); 1.38-1.42 (m, 2H), 1.62-1.99 (m, 19H), 2.16-2.23 (m, 2H),2.30-2.38 (m, 2H), 3.79 (quintet, J = 9.0 Hz, 1H), 3.92-3.95 (m, 1H),4.49 (s, 1H), 4.51 (s, 2H), 7.05 (s, 1H), 7.31 (s, 1H), 8.34-8.37(m, 1H)II-146

(DMSO-d6); 1.02 (d, 6H, J = 6.0 Hz), 1.34 (s, 6H), 1.34-1.41 (m, 2H),1.62-1.73 (m, 6H), 1.82-1.86 (m, 2H), 2.04 (br, 3H), 3.23 (quintet, J =9.0 Hz, 1H), 3.91-3.94 (m, 1H), 4.43 (s, 2H), 4.49 (s, 1H), 7.04 (t, 1H,J = 9.0 Hz), 7.29 (t, 2H, J = 9.0 Hz), 7.62 (d, 2H, J = 9.0 Hz),8.33-8.35 (m, 1H), 9.40 (s, 1H) II-147

(DMSO-d6); 1.19 (s, 6H), 1.18-1.41 (m, 4H), 1.75- 1.85 (m, 8H),2.18-2.27 (m, 2H), 3.34-3.42 (m, 1H), 3.60-3.70 (m, 1H), 3.90 (quintet,J = 9.0 Hz, 1H), 4.23 (s, 2H), 4.58 (d, J = 3.0 Hz, 1H), 7.03 (s, 1H),7.27 (s, 1H), 8.54-8.56 (m, 1H) II-148

(DMSO-d6); 1.22 (s, 6H), 1.82-1.92 (m, 4H), 2.24- 2.30 (m, 2H), 3.75 (s,3H), 3.94-4.03 (m, 1H), 4.28 (s, 2H), 6.93 (dd, J = 3.0 Hz, 6.0 Hz, 2H),7.06 (s, 1H), 7.30 (s, 1H), 7.64 (dd, J = 3.0 Hz, 6.0 Hz, 2H) II-149

(DMSO-d6) 1.26-2.06(m, 29H), 3.52-3.60(m, 1H), 3.90-3.98(m, 1H), 4.36(s,2H), 4.49(s, 1H), 6.95(brs, 1H), 7.26(brs, 1H), 8.31(d, J = 6.8 Hz, 1H)II-150

(DMSO-d6) 0.84-2.06(m, 25H), 3.62-3.69(m, 1H), 3.90-3.98(m, 1H), 4.42(s,1H), 4.45(s, 2H), 7.34- 7.65(m, 4H), 8.32-8.37(m, 1H) II-151

(DMSO-d6) 0.66-2.13(m, 25H), 2.33(s, 3H), 3.70- 3.73(m, 1H),3.94-3.98(m, 1H), 4.15(s, 2H), 4.47(s, 1H), 7.25-7.37(m, 3H), 7.67(d, J= 8.4 Hz, 2H), 8.32- 8.37(m, 1H)

TABLE 28 No. Structure NMR II-152

(DMSO-d6) 0.90-2.07(m, 25H), 2.97(s, 3H), 3.69- 3.72(m, 1H),3.90-3.98(m, 1H), 4.31(s, 2H), 4.46(s, 1H), 7.77(s, 1H), 8.35(d, J = 5.6Hz, 1H) II-153

(DMSO-d6) 1.25-2.15(m, 27H), 3.48-3.60(m, 1H), 3.63-3.77(m, 2H),3.90-3.98(m, 1H), 4.11-4.22(m, 2H), 4.40-4.63(m, 3H), 8.32-8.50(m, 1H)II-154

(DMSO-d6) 1.25-2.17(m, 29H), 3.20(t, J = 7.2 Hz, 2H), 3.42(t, J = 6.8Hz, 2H), 3.60-3.65(m, 1H), 3.92- 3.98(m, 1H), 4.35(s, 2H), 4.46(s, 1H),8.36(d, J = 7.6 Hz, 1H) II-155

(DMSO-d6) 0.88-2.07(m, 25H), 3.65-3.62(m, 1H), 3.90-3.98(m, 1H), 4.35(s,2H), 4.47(brs, 1H), 7.00- 7.50(brs, 2H), 8.37(d, J = 6.8 Hz, 1H)

The following compounds as the present compound can be synthesized aswell as the above Example. The abbreviations used in the tables are asfollows.

Et ethylPro n-propyli-Pro isopropylBu n-butyli-Bu isobutylThe abbreviations used for R³ are as follows.

The abbreviations used for R⁴ are as follows.

5-OH-2-Adm encompasses syn and anti. Preferred is anti.

Concretely, the defined compound is shown by using the formula (V).

(Compound No., R², R³, X, Y, Z, R⁴,R⁵)=(1-1,i-Bu,A-1,S,S,O,1-Adm,H),(1-2,i-Bu,A-2,S,S,O,1-Adm,H),(1-3,i-Bu,A-3,S,S,O,1-Adm,H),(1-4,i-Bu,A-4,S,S,O,1-Adm,H),(1-5,i-Bu,A-5,S,S,O,1-Adm,H),(1-6,i-Bu,A-6,S,S,O,1-Adm,H),(1-7,i-Bu,A-7,S,S,O,1-Adm,H),(1-8,i-Bu,A-8,S,S,O,1-Adm,H),(1-9,i-Bu,A-9,S,S,O,1-Adm,H),(1-10,i-Bu,A-10,S,S,O,1-Adm,H),(1-11,i-Bu,A-11,S,S,O,1-Adm,H),(1-12,i-Bu,A-12,S,S,O,1-Adm,H),(1-13,i-Bu,A-13,S,S,O,1-Adm,H),(1-14,i-Bu,A-14,S,S,O,1-Adm,H),(1-15,i-Bu,A-15,S,S,O,1-Adm,H),(1-16,i-Bu,A-16,S,S,O,1-Adm,H),(1-17,i-Bu,A-17,S,S,O,1-Adm,H),(1-18,i-Bu,A-18,S,S,O,1-Adm,H),(1-19,i-Bu,A-19,S,S,O,1-Adm,H),(1-20,i-Bu,A-20,S,S,O,1-Adm,H),(1-21,i-Bu,A-21,S,S,O,1-Adm,H),(1-22,i-Bu,A-22,S,S,O,1-Adm,H),(1-23,i-Bu,A-23,S,S,O,1-Adm,H),(1-24,i-Bu,A-24,S,S,O,1-Adm,H),(1-25,i-Bu,A-25,S,S,O,1-Adm,H),(1-26,i-Bu,A-26,S,S,O,1-Adm,H),(1-27,i-Bu,A-27,S,S,O,1-Adm,H),(1-28,i-Bu,A-28,S,S,O,1-Adm,H),(1-29,i-Bu,A-29,S,S,O,1-Adm,H),(1-30,i-Bu,A-30,S,S,O,1-Adm,H),(1-31,i-Bu,A-31,S,S,O,1-Adm,H),(1-32,i-Bu,A-32,S,S,O,1-Adm,H),(1-33,i-Bu,A-33,S,S,O,1-Adm,H),(1-34,i-Bu,A-34,S,S,O,1-Adm,H),(1-35,i-Bu,A-35,S,S,O,1-Adm,H),(1-36,i-Bu,A-36,S,S,O,1-Adm,H),(1-37,i-Bu,A-1,S,S,O,2-Adm,H),(1-38,i-Bu,A-2,S,S,O,2-Adm,H),(1-39,i-Bu,A-3,S,S,O,2-Adm,H),(1-40,i-Bu,A-4,S,S,O,2-Adm,H),(1-41,i-Bu,A-5,S,S,O,2-Adm,H),(1-42,i-Bu,A-6,S,S,O,2-Adm,H),(1-43,i-Bu,A-7,S,S,O,2-Adm,H),(1-44,i-Bu,A-8,S,S,O,2-Adm,H),(1-45,i-Bu,A-9,S,S,O,2-Adm,H),(1-46,i-Bu,A-10,S,S,O,2-Adm,H),(1-47,i-Bu,A-1,S,S,O,2-Adm,H),(1-48,i-Bu,A-12,S,S,O,2-Adm,H),(1-49,i-Bu,A-13,S,S,O,2-Adm,H),(1-50,i-Bu,A-14,S,S,O,2-Adm,H),(1-51,i-Bu,A-15,S,S,O,2-Adm,H),(1-52,i-Bu,A-16,S,S,O,2-Adm,H),(1-53,i-Bu,A-17,S,S,O,2-Adm,H),(1-54,i-Bu,A-18,S,S,O,2-Adm,H),(1-55,i-Bu,A-19,S,S,O,2-Adm,H),(1-56,i-Bu,A-20,S,S,O,2-Adm,H),(1-57,i-Bu,A-21,S,S,O,2-Adm,H),(1-58,i-Bu,A-22,S,S,O,2-Adm,H),(1-59,i-Bu,A-23,S,S,O,2-Adm,H),(1-60,i-Bu,A-24,S,S,O,2-Adm,H),(1-61,i-Bu,A-25,S,S,O,2-Adm,H),(1-62,i-Bu,A-26,S,S,O,2-Adm,H),(1-63,i-Bu,A-27,S,S,O,2-Adm,H),(1-64,i-Bu,A-28,S,S,O,2-Adm,H),(1-65,i-Bu,A-29,S,S,O,2-Adm,H),(1-66,i-Bu,A-30,S,S,O,2-Adm,H),(1-67,i-Bu,A-31,S,S,O,2-Adm,H),(1-68,i-Bu,A-32,S,S,O,2-Adm,H),(1-69,i-Bu,A-33,S,S,O,2-Adm,H),(1-70,i-Bu,A-34,S,S,O,2-Adm,H),(1-71,i-Bu,A-35,S,S,O,2-Adm,H),(1-72,i-Bu,A-36,S,S,O,2-Adm,H),(1-73,i-Bu,A-1,S,S,O,5-OH-2-Adm,H),(1-74,i-Bu,A-2,S,S,O,5-OH-2-Adm,H),(1-75,i-Bu,A-3,S,S,O,5-OH-2-Adm,H),(1-76,i-Bu,A-4,S,S,O,5-OH-2-Adm,H),(1-77,i-Bu,A-5,S,S,O,5-OH-2-Adm,H),(1-78,i-Bu,A-6,S,S,O,5-OH-2-Adm,H),(1-79,i-Bu,A-7,S,S,O,5-OH-2-Adm,H),(1-80,i-Bu,A-8,S,S,O,5-OH-2-Adm,H),(1-81,i-Bu,A-9,S,S,O,5-OH-2-Adm,H),(1-82,i-Bu,A-10,S,S,O,5-OH-2-Adm,H),(1-83,i-Bu,A-11,S,S,O,5-OH-2-Adm,H),(1-84,i-Bu,A-12,S,S,O,5-OH-2-Adm,H),(1-85,i-Bu,A-13,S,S,O,5-OH-2-Adm,H),(1-86,i-Bu,A-14,S,S,O,5-OH-2-Adm,H),(1-87,i-Bu,A-15,S,S,O,5-OH-2-Adm,H),(1-88,i-Bu,A-16,S,S,O,5-OH-2-Adm,H),(1-89,i-Bu,A-17,S,S,O,5-OH-2-Adm,H),(1-90,i-Bu,A-18,S,S,O,5-OH-2-Adm,H),(1-91,i-Bu,A-19,S,S,O,5-OH-2-Adm,H),(1-92,i-Bu,A-20,S,S,O,5-OH-2-Adm,H),(1-93,i-Bu,A-21,S,S,O,5-OH-2-Adm,H),(1-94,i-Bu,A-22,S,S,O,5-OH-2-Adm,H),(1-95,i-Bu,A-23,S,S,O,5-OH-2-Adm,H),(1-96,i-Bu,A-24,S,S,O,5-OH-2-Adm,H),(1-97,i-Bu,A-25,S,S,O,5-OH-2-Adm,H),(1-98,i-Bu,A-26,S,S,O,5-OH-2-Adm,H),(1-99,i-Bu,A-27,S,S,O,5-OH-2-Adm,H),(1-100,i-Bu,A-28,S,S,O,5-OH-2-Adm,H),(1-101,i-Bu,A-29,S,S,O,5-OH-2-Adm,H),(1-102,i-Bu,A-30,S,S,O,5-OH-2-Adm,H),(1-103,i-Bu,A-31,S,S,O,5-OH-2-Adm,H),(1-104,i-Bu,A-32,S,S,O,5-OH-2-Adm,H),(1-105,i-Bu,A-33,S,S,O,5-OH-2-Adm,H),(1-106,i-Bu,A-34,S,S,O,5-OH-2-Adm,H),(1-107,i-Bu,A-35,S,S,O,5-OH-2-Adm,H),(1-108,i-Bu,A-36,S,S,O,5-OH-2-Adm,H),(1-109,i-Bu,B-1,S,S,O,1-Adm,H),(1-110,i-Bu,B-2,S,S,O,1-Adm,H),(1-111,i-Bu,B-3,S,S,O,1-Adm,H),(1-112,i-Bu,B-4,S,S,O,1-Adm,H),(1-113,i-Bu,B-5,S,S,O,1-Adm,H),(1-114,i-Bu,B-6,S,S,O,1-Adm,H),(1-115,i-Bu,B-7,S,S,O,1-Adm,H),(1-116,i-Bu,B-8,S,S,O,1-Adm,H),(1-117,i-Bu,B-9,S,S,O,1-Adm,H),(1-118,i-Bu,B-10,S,S,O,1-Adm,H),(1-119,i-Bu,B-11,S,S,O,1-Adm,H),(1-120,i-Bu,B-12,S,S,O,1-Adm,H),(1-121,i-Bu,B-13,S,S,O,1-Adm,H),(1-122,i-Bu,B-14,S,S,O,1-Adm,H),(1-123,i-Bu,B-15,S,S,O,1-Adm,H),(1-124,i-Bu,B-16,S,S,O,1-Adm,H),(1-125,i-Bu,B-17,S,S,O,1-Adm,H),(1-126,i-Bu,B-18,S,S,O,1-Adm,H),(1-127,i-Bu,B-19,S,S,O,1-Adm,H),(1-128,i-Bu,B-20,S,S,O,1-Adm,H),(1-129,i-Bu,B-21,S,S,O,1-Adm,H),(1-130,i-Bu,B-22,S,S,O,1-Adm,H),(1-131,i-Bu,B-23,S,S,O,1-Adm,H),(1-132,i-Bu,B-24,S,S,O,1-Adm,H),(1-133,i-Bu,B-25,S,S,O,1-Adm,H),(1-134,i-Bu,B-26,S,S,O,1-Adm,H),(1-135,i-Bu,B-27,S,S,O,1-Adm,H),(1-136,i-Bu,B-28,S,S,O,1-Adm,H),(1-137,i-Bu,B-29,S,S,O,1-Adm,H),(1-138,i-Bu,B-30,S,S,O,1-Adm,H),(1-139,i-Bu,B-31,S,S,O,1-Adm,H),(1-140,i-Bu,B-32,S,S,O,1-Adm,H),(1-141,i-Bu,B-33,S,S,O,1-Adm,H),(1-142,i-Bu,B-34,S,S,O,1-Adm,H),(1-143,i-Bu,B-35,S,S,O,1-Adm,H),(1-144,i-Bu,B-36,S,S,O,1-Adm,H),(1-145,i-Bu,B-1,S,S,O,2-Adm,H),(1-146,i-Bu,B-2,S,S,O,2-Adm,H),(1-147,i-Bu,B-3,S,S,O,2-Adm,H),(1-148,i-Bu,B-4,S,S,O,2-Adm,H),(1-149,i-Bu,B-5,S,S,O,2-Adm,H),(1-150,i-Bu,B-6,S,S,O,2-Adm,H),(1-151,i-Bu,B-7,S,S,O,2-Adm,H),(1-152,i-Bu,B-8,S,S,O,2-Adm,H),(1-153,i-Bu,B-9,S,S,O,2-Adm,H),(1-154,i-Bu,B-10,S,S,O,2-Adm,H),(1-155,i-Bu,B-11,S,S,O,2-Adm,H),(1-156,i-Bu,B-12,S,S,O,2-Adm,H),(1-157,i-Bu,B-13,S,S,O,2-Adm,H),(1-158,i-Bu,B-14,S,S,O,2-Adm,H),(1-159,i-Bu,B-15,S,S,O,2-Adm,H),(1-160,i-Bu,B-16,S,S,O,2-Adm,H),(1-161,i-Bu,B-17,S,S,O,2-Adm,H),(1-162,i-Bu,B-18,S,S,O,2-Adm,H),(1-163,i-Bu,B-19,S,S,O,2-Adm,H),(1-164,i-Bu,B-20,S,S,O,2-Adm,H),(1-165,i-Bu,B-21,S,S,O,2-Adm,H),(1-166,i-Bu,B-22,S,S,O,2-Adm,H),(1-167,i-Bu,B-23,S,S,O,2-Adm,H),(1-168,i-Bu,B-24,S,S,O,2-Adm,H),(1-169,i-Bu,B-25,S,S,O,2-Adm,H),(1-170,i-Bu,B-26,S,S,O,2-Adm,H),(1-171,i-Bu,B-27,S,S,O,2-Adm,H),(1-172,i-Bu,B-28,S,S,O,2-Adm,H),(1-173,i-Bu,B-29,S,S,O,2-Adm,H),(1-174,i-Bu,B-30,S,S,O,2-Adm,H),(1-175,i-Bu,B-31,S,S,O,2-Adm,H),(1-176,i-Bu,B-32,S,S,O,2-Adm,H),(1-177,i-Bu,B-33,S,S,O,2-Adm,H),(1-178,i-Bu,B-34,S,S,O,2-Adm,H),(1-179,i-Bu,B-35,S,S,O,2-Adm,H),(1-180,i-Bu,B-36,S,S,O,2-Adm,H),(1-181,i-Bu,B-1,S,S,O,5-OH-2-Adm,H),(1-182,i-Bu,B-2,S,S,O,5-OH-2-Adm,H),(1-183,i-Bu,B-3,S,S,O,5-OH-2-Adm,H),(1-184,i-Bu,B-4,S,S,O,5-OH-2-Adm,H),(1-185,i-Bu,B-5,S,S,O,5-OH-2-Adm,H),(1-186,i-Bu,B-6,S,S,O,5-OH-2-Adm,H),(1-187,i-Bu,B-7,S,S,O,5-OH-2-Adm,H),(1-188,i-Bu,B-8,S,S,O,5-OH-2-Adm,H),(1-189,i-Bu,B-9,S,S,O,5-OH-2-Adm,H),(1-190,i-Bu,B-10,S,S,O,5-OH-2-Adm,H),(1-191,i-Bu,B-11,S,S,O,5-OH-2-Adm,H),(1-192,i-Bu,B-12,S,S,O,5-OH-2-Adm,H),(1-193,i-Bu,B-13,S,S,O,5-OH-2-Adm,H),(1-194,i-Bu,B-14,S,S,O,5-OH-2-Adm,H),(1-195,i-Bu,B-15,S,S,O,5-OH-2-Adm,H),(1-196,i-Bu,B-16,S,S,O,5-OH-2-Adm,H),(1-197,i-Bu,B-17,S,S,O,5-OH-2-Adm,H),(1-198,i-Bu,B-18,S,S,O,5-OH-2-Adm,H),(1-199,i-Bu,B-19,S,S,O,5-OH-2-Adm,H),(1-200,i-Bu,B-20,S,S,O,5-OH-2-Adm,H),(1-201,i-Bu,B-21,S,S,O,5-OH-2-Adm,H),(1-202,i-Bu,B-22,S,S,O,5-OH-2-Adm,H),(1-203,i-Bu,B-23,S,S,O,5-OH-2-Adm,H),(1-204,i-Bu,B-24,S,S,O,5-OH-2-Adm,H),(1-205,i-Bu,B-25,S,S,O,5-OH-2-Adm,H),(1-206,i-Bu,B-26,S,S,O,5-OH-2-Adm,H),(1-207,i-Bu,B-27,S,S,O,5-OH-2-Adm,H),(1-208,i-Bu,B-28,S,S,O,5-OH-2-Adm,H),(1-209,i-Bu,B-29,S,S,O,5-OH-2-Adm,H),(1-210,i-Bu,B-30,S,S,O,5-OH-2-Adm,H),(1-211,i-Bu,B-31,S,S,O,5-OH-2-Adm,H),(1-212,i-Bu,B-32,S,S,O,5-OH-2-Adm,H),(1-213,i-Bu,B-33,S,S,O,5-OH-2-Adm,H),(1-214,i-Bu,B-34,S,S,O,5-OH-2-Adm,H),(1-215,i-Bu,B-35,S,S,O,5-OH-2-Adm,H),(1-216,i-Bu,B-36,S,S,O,5-OH-2-Adm,H),(1-217,i-Bu,C-1,S,S,O,1-Adm,H),(1-218,i-Bu,C-2,S,S,O,1-Adm,H),(1-219,i-Bu,C-3,S,S,O,1-Adm,H),(1-220,i-Bu,C-4,S,S,O,1-Adm,H),(1-221,i-Bu,C-5,S,S,O,1-Adm,H),(1-222,i-Bu,C-6,S,S,O,1-Adm,H),(1-223,i-Bu,C-7,S,S,O,1-Adm,H),(1-224,i-Bu,C-8,S,S,O,1-Adm,H),(1-225,i-Bu,C-9,S,S,O,1-Adm,H),(1-226,i-Bu,C-10,S,S,O,1-Adm,H),(1-227,i-Bu,C-11,S,S,O,1-Adm,H),(1-228,i-Bu,C-12,S,S,O,1-Adm,H),(1-229,i-Bu,C-13,S,S,O,1-Adm,H),(1-230,i-Bu,C-14,S,S,O,1-Adm,H),(1-231,i-Bu,C-15,S,S,O,1-Adm,H),(1-232,i-Bu,C-16,S,S,O,1-Adm,H),(1-233,i-Bu,C-17,S,S,O,1-Adm,H),(1-234,i-Bu,C-18,S,S,O,1-Adm,H),(1-235,i-Bu,C-19,S,S,O,1-Adm,H),(1-236,i-Bu,C-20,S,S,O,1-Adm,H),(1-237,i-Bu,C-21,S,S,O,1-Adm,H),(1-238,i-Bu,C-22,S,S,O,1-Adm,H),(1-239,i-Bu,C-23,S,S,O,1-Adm,H),(1-240,i-Bu,C-24,S,S,O,1-Adm,H),(1-241,i-Bu,C-25,S,S,O,1-Adm,H),(1-242,i-Bu,C-26,S,S,O,1-Adm,H),(1-243,i-Bu,C-27,S,S,O,1-Adm,H),(1-244,i-Bu,C-28,S,S,O,1-Adm,H),(1-245,i-Bu,C-29,S,S,O,1-Adm,H),(1-246,i-Bu,C-30,S,S,O,1-Adm,H),(1-247,i-Bu,C-31,S,S,O,1-Adm,H),(1-248,i-Bu,C-32,S,S,O,1-Adm,H),(1-249,i-Bu,C-33,S,S,O,1-Adm,H),(1-250,i-Bu,C-34,S,S,O,1-Adm,H),(1-251,i-Bu,C-35,S,S,O,1-Adm,H),(1-252,i-Bu,C-36,S,S,O,1-Adm,H),(1-253,i-Bu,C-1,S,S,O,2-Adm,H),(1-254,i-Bu,C-2,S,S,O,2-Adm,H),(1-255,i-Bu,C-3,S,S,O,2-Adm,H),(1-256,i-Bu,C-4,S,S,O,2-Adm,H),(1-257,i-Bu,C-5,S,S,O,2-Adm,H),(1-258,i-Bu,C-6,S,S,O,2-Adm,H),(1-259,i-Bu,C-7,S,S,O,2-Adm,H),(1-260,i-Bu,C-8,S,S,O,2-Adm,H),(1-261,i-Bu,C-9,S,S,O,2-Adm,H),(1-262,i-Bu,C-10,S,S,O,2-Adm,H),(1-263,i-Bu,C-11,S,S,O,2-Adm,H),(1-264,i-Bu,C-12,S,S,O,2-Adm,H),(1-265,i-Bu,C-13,S,S,O,2-Adm,H),(1-266,i-Bu,C-14,S,S,O,2-Adm,H),(1-267,i-Bu,C-15,S,S,O,2-Adm,H),(1-268,i-Bu,C-16,S,S,O,2-Adm,H),(1-269,i-Bu,C-17,S,S,O,2-Adm,H),(1-270,i-Bu,C-18,S,S,O,2-Adm,H),(1-271,i-Bu,C-19,S,S,O,2-Adm,H),(1-272,i-Bu,C-20,S,S,O,2-Adm,H),(1-273,i-Bu,C-21,S,S,O,2-Adm,H),(1-274,i-Bu,C-22,S,S,O,2-Adm,H),(1-275,i-Bu,C-23,S,S,O,2-Adm,H),(1-276,i-Bu,C-24,S,S,O,2-Adm,H),(1-277,i-Bu,C-25,S,S,O,2-Adm,H),(1-278,i-Bu,C-26,S,S,O,2-Adm,H),(1-279,i-Bu,C-27,S,S,O,2-Adm,H),(1-280,i-Bu,C-28,S,S,O,2-Adm,H),(1-281,i-Bu,C-29,S,S,O,2-Adm,H),(1-282,i-Bu,C-30,S,S,O,2-Adm,H),(1-283,i-Bu,C-31,S,S,O,2-Adm,H),(1-284,i-Bu,C-32,S,S,O,2-Adm,H),(1-285,i-Bu,C-33,S,S,O,2-Adm,H),(1-286,i-Bu,C-34,S,S,O,2-Adm,H),(1-287,i-Bu,C-35,S,S,O,2-Adm,H),(1-288,i-Bu,C-36,S,S,O,2-Adm,H),(1-289,i-Bu,C-1,S,S,O,5-OH-2-Adm,H),(1-290,i-Bu,C-2,S,S,O,5-OH-2-Adm,H),(1-291,i-Bu,C-3,S,S,O,5-OH-2-Adm,H),(1-292,i-Bu,C-4,S,S,O,5-OH-2-Adm,H),(1-293,i-Bu,C-5,S,S,O,5-OH-2-Adm,H),(1-294,i-Bu,C-6,S,S,O,5-OH-2-Adm,H),(1-295,i-Bu,C-7,S,S,O,5-OH-2-Adm,H),(1-296,i-Bu,C-8,S,S,O,5-OH-2-Adm,H),(1-297,i-Bu,C-9,S,S,O,5-OH-2-Adm,H),(1-298,i-Bu,C-10,S,S,O,5-OH-2-Adm,H),(1-299,i-Bu,C-11,S,S,O,5-OH-2-Adm,H),(1-300,i-Bu,C-12,S,S,O,5-OH-2-Adm,H),(1-301,i-Bu,C-13,S,S,O,5-OH-2-Adm,H),(1-302,i-Bu,C-14,S,S,O,5-OH-2-Adm,H),(1-303,i-Bu,C-15,S,S,O,5-OH-2-Adm,H),(1-304,i-Bu,C-16,S,S,O,5-OH-2-Adm,H),(1-305,i-Bu,C-17,S,S,O,5-OH-2-Adm,H),(1-306,i-Bu,C-18,S,S,O,5-OH-2-Adm,H),(1-307,i-Bu,C-19,S,S,O,5-OH-2-Adm,H),(1-308,i-Bu,C-20,S,S,O,5-OH-2-Adm,H),(1-309,i-Bu,C-21,S,S,O,5-OH-2-Adm,H),(1-310,i-Bu,C-22,S,S,O,5-OH-2-Adm,H),(1-311,i-Bu,C-23,S,S,O,5-OH-2-Adm,H),(1-312,i-Bu,C-24,S,S,O,5-OH-2-Adm,H),(1-313,i-Bu,C-25,S,S,O,5-OH-2-Adm,H),(1-314,i-Bu,C-26,S,S,O,5-OH-2-Adm,H),(1-315,i-Bu,C-27,S,S,O,5-OH-2-Adm,H),(1-316,i-Bu,C-28,S,S,O,5-OH-2-Adm,H),(1-317,i-Bu,C-29,S,S,O,5-OH-2-Adm,H),(1-318,i-Bu,C-30,S,S,O,5-OH-2-Adm,H),(1-319,i-Bu,C-31,S,S,O,5-OH-2-Adm,H),(1-320,i-Bu,C-32,S,S,O,5-OH-2-Adm,H),(1-321,i-Bu,C-33,S,S,O,5-OH-2-Adm,H),(1-322,i-Bu,C-34,S,S,O,5-OH-2-Adm,H),(1-323,i-Bu,C-35,S,S,O,5-OH-2-Adm,H),(1-324,i-Bu,C-36,S,S,O,5-OH-2-Adm,H),(1-325,i-Bu,D-1,S,S,O,1-Adm,H),(1-326,i-Bu,D-2,S,S,O,1-Adm,H),(1-327,i-Bu,D-3,S,S,O,1-Adm,H),(1-328,i-Bu,D-4,S,S,O,1-Adm,H),(1-329,i-Bu,D-5,S,S,O,1-Adm,H),(1-330,i-Bu,D-6,S,S,O,1-Adm,H),(1-331,i-Bu,D-7,S,S,O,1-Adm,H),(1-332,i-Bu,D-8,S,S,O,1-Adm,H),(1-333,i-Bu,D-9,S,S,O,1-Adm,H),(1-334,i-Bu,D-10,S,S,O,1-Adm,H),(1-335,i-Bu,D-11,S,S,O,1-Adm,H),(1-336,i-Bu,D-12,S,S,O,1-Adm,H),(1-337,i-Bu,D-13,S,S,O,1-Adm,H),(1-338,i-Bu,D-14,S,S,O,1-Adm,H),(1-339,i-Bu,D-15,S,S,O,1-Adm,H),(1-340,i-Bu,D-16,S,S,O,1-Adm,H),(1-341,i-Bu,D-17,S,S,O,1-Adm,H),(1-342,i-Bu,D-18,S,S,O,1-Adm,H),(1-343,i-Bu,D-19,S,S,O,1-Adm,H),(1-344,i-Bu,D-20,S,S,O,1-Adm,H),(1-345,i-Bu,D-21,S,S,O,1-Adm,H),(1-346,i-Bu,D-22,S,S,O,1-Adm,H),(1-347,i-Bu,D-23,S,S,O,1-Adm,H),(1-348,i-Bu,D-24,S,S,O,1-Adm,H),(1-349,i-Bu,D-25,S,S,O,1-Adm,H),(1-350,i-Bu,D-26,S,S,O,1-Adm,H),(1-351,i-Bu,D-27,S,S,O,1-Adm,H),(1-352,i-Bu,D-28,S,S,O,1-Adm,H),(1-353,i-Bu,D-29,S,S,O,1-Adm,H),(1-354,i-Bu,D-30,S,S,O,1-Adm,H),(1-355,i-Bu,D-31,S,S,O,1-Adm,H),(1-356,i-Bu,D-32,S,S,O,1-Adm,H),(1-357,i-Bu,D-33,S,S,O,1-Adm,H),(1-358,i-Bu,D-34,S,S,O,1-Adm,H),(1-359,i-Bu,D-35,S,S,O,1-Adm,H),(1-360,i-Bu,D-36,S,S,O,1-Adm,H),(1-361,i-Bu,D-1,S,S,O,2-Adm,H),(1-362,i-Bu,D-2,S,S,O,2-Adm,H),(1-363,i-Bu,D-3,S,S,O,2-Adm,H),(1-364,i-Bu,D-4,S,S,O,2-Adm,H),(1-365,i-Bu,D-5,S,S,O,2-Adm,H),(1-366,i-Bu,D-6,S,S,O,2-Adm,H),(1-367,i-Bu,D-7,S,S,O,2-Adm,H),(1-368,i-Bu,D-8,S,S,O,2-Adm,H),(1-369,i-Bu,D-9,S,S,O,2-Adm,H),(1-370,i-Bu,D-10,S,S,O,2-Adm,H),(1-371,i-Bu,D-11,S,S,O,2-Adm,H),(1-372,i-Bu,D-12,S,S,O,2-Adm,H),(1-373,i-Bu,D-13,S,S,O,2-Adm,H),(1-374,i-Bu,D-14,S,S,O,2-Adm,H),(1-375,i-Bu,D-15,S,S,O,2-Adm,H),(1-376,i-Bu,D-16,S,S,O,2-Adm,H),(1-377,i-Bu,D-17,S,S,O,2-Adm,H),(1-378,i-Bu,D-18,S,S,O,2-Adm,H),(1-379,i-Bu,D-19,S,S,O,2-Adm,H),(1-380,i-Bu,D-20,S,S,O,2-Adm,H),(1-381,i-Bu,D-21,S,S,O,2-Adm,H),(1-382,i-Bu,D-22,S,S,O,2-Adm,H),(1-383,i-Bu,D-23,S,S,O,2-Adm,H),(1-384,i-Bu,D-24,S,S,O,2-Adm,H),(1-385,i-Bu,D-25,S,S,O,2-Adm,H),(1-386,i-Bu,D-26,S,S,O,2-Adm,H),(1-387,i-Bu,D-27,S,S,O,2-Adm,H),(1-388,i-Bu,D-28,S,S,O,2-Adm,H),(1-389,i-Bu,D-29,S,S,O,2-Adm,H),(1-390,i-Bu,D-30,S,S,O,2-Adm,H),(1-391,i-Bu,D-31,S,S,O,2-Adm,H),(1-392,i-Bu,D-32,S,S,O,2-Adm,H),(1-393,i-Bu,D-33,S,S,O,2-Adm,H),(1-394,i-Bu,D-34,S,S,O,2-Adm,H),(1-395,i-Bu,D-35,S,S,O,2-Adm,H),(1-396,i-Bu,D-36,S,S,O,2-Adm,H),(1-397,i-Bu,D-1,S,S,O,5-OH-2-Adm,H),(1-398,i-Bu,D-2,S,S,O,5-OH-2-Adm,H),(1-399,i-Bu,D-3,S,S,O,5-OH-2-Adm,H),(1-400,i-Bu,D-4,S,S,O,5-OH-2-Adm,H),(1-401,i-Bu,D-5,S,S,O,5-OH-2-Adm,H),(1-402,i-Bu,D-6,S,S,O,5-OH-2-Adm,H),(1-403,i-Bu,D-7,S,S,O,5-OH-2-Adm,H),(1-404,i-Bu,D-8,S,S,O,5-OH-2-Adm,H),(1-405,i-Bu,D-9,S,S,O,5-OH-2-Adm,H),(1-406,i-Bu,D-10,S,S,O,5-OH-2-Adm,H),(1-407,i-Bu,D-11,S,S,O,5-OH-2-Adm,H),(1-408,i-Bu,D-12,S,S,O,5-OH-2-Adm,H),(1-409,i-Bu,D-13,S,S,O,5-OH-2-Adm,H),(1-410,i-Bu,D-14,S,S,O,5-OH-2-Adm,H),(1-411,i-Bu,D-15,S,S,O,5-OH-2-Adm,H),(1-412,i-Bu,D-16,S,S,O,5-OH-2-Adm,H),(1-413,i-Bu,D-17,S,S,O,5-OH-2-Adm,H),(1-414,i-Bu,D-18,S,S,O,5-OH-2-Adm,H),(1-415,i-Bu,D-19,S,S,O,5-OH-2-Adm,H),(1-416,i-Bu,D-20,S,S,O,5-OH-2-Adm,H),(1-417,i-Bu,D-21,S,S,O,5-OH-2-Adm,H),(1-418,i-Bu,D-22,S,S,O,5-OH-2-Adm,H),(1-419,i-Bu,D-23,S,S,O,5-OH-2-Adm,H),(1-420,i-Bu,D-24,S,S,O,5-OH-2-Adm,H),(1-421,i-Bu,D-25,S,S,O,5-OH-2-Adm,H),(1-422,i-Bu,D-26,S,S,O,5-OH-2-Adm,H),(1-423,i-Bu,D-27,S,S,O,5-OH-2-Adm,H),(1-424,i-Bu,D-28,S,S,O,5-OH-2-Adm,H),(1-425,i-Bu,D-29,S,S,O,5-OH-2-Adm,H),(1-426,i-Bu,D-30,S,S,O,5-OH-2-Adm,H),(1-427,i-Bu,D-31,S,S,O,5-OH-2-Adm,H),(1-428,i-Bu,D-32,S,S,O,5-OH-2-Adm,H),(1-429,i-Bu,D-33,S,S,O,5-OH-2-Adm,H),(1-430,i-Bu,D-34,S,S,O,5-OH-2-Adm,H),(1-431,i-Bu,D-35,S,S,O,5-OH-2-Adm,H),(1-432,i-Bu,D-36,S,S,O,5-OH-2-Adm,H),(1-433,i-Bu,E-1,S,S,O,1-Adm,H),(1-434,i-Bu,E-2,S,S,O,1-Adm,H),(1-435,i-Bu,E-3,S,S,O,1-Adm,H),(1-436,i-Bu,E-4,S,S,O,1-Adm,H),(1-437,i-Bu,E-5,S,S,O,1-Adm,H),(1-438,i-Bu,E-6,S,S,O,1-Adm,H),(1-439,i-Bu,E-7,S,S,O,1-Adm,H),(1-440,i-Bu,E-8,S,S,O,1-Adm,H),(1-441,i-Bu,E-9,S,S,O,1-Adm,H),(1-442,i-Bu,E-10,S,S,O,1-Adm,H),(1-443,i-Bu,E-11,S,S,O,1-Adm,H),(1-444,i-Bu,E-12,S,S,O,1-Adm,H),(1-445,i-Bu,E-13,S,S,O,1-Adm,H),(1-446,i-Bu,E-14,S,S,O,1-Adm,H),(1-447,i-Bu,E-15,S,S,O,1-Adm,H),(1-448,i-Bu,E-16,S,S,O,1-Adm,H),(1-449,i-Bu,E-17,S,S,O,1-Adm,H),(1-450,i-Bu,E-18,S,S,O,1-Adm,H),(1-451,i-Bu,E-19,S,S,O,1-Adm,H),(1-452,i-Bu,E-20,S,S,O,1-Adm,H),(1-453,i-Bu,E-21,S,S,O,1-Adm,H),(1-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m,H),(1-606,i-Bu,F-30,S,S,O,2-Adm,H),(1-607,i-Bu,F-31,S,S,O,2-Adm,H),(1-608,i-Bu,F-32,S,S,O,2-Adm,H),(1-609,i-Bu,F-33,S,S,O,2-Adm,H),(1-610,i-Bu,F-34,S,S,O,2-Adm,H),(1-611,i-Bu,F-35,S,S,O,2-Adm,H),(1-612,i-Bu,F-36,S,S,O,2-Adm,H),(1-613,i-Bu,F-1,S,S,O,5-OH-2-Adm,H),(1-614,i-Bu,F-2,S,S,O,5-OH-2-Adm,H),(1-615,i-Bu,F-3,S,S,O,5-OH-2-Adm,H),(1-616,i-Bu,F-4,S,S,O,5-OH-2-Adm,H),(1-617,i-Bu,F-5,S,S,O,5-OH-2-Adm,H),(1-618,i-Bu,F-6,S,S,O,5-OH-2-Adm,H),(1-619,i-Bu,F-7,S,S,O,5-OH-2-Adm,H),(1-620,i-Bu,F-8,S,S,O,5-OH-2-Adm,H),(1-621,i-Bu,F-9,S,S,O,5-OH-2-Adm,H),(1-622,i-Bu,F-10,S,S,O,5-OH-2-Adm,H),(1-623,i-Bu,F-11,S,S,O,5-OH-2-Adm,H),(1-624,i-Bu,F-12,S,S,O,5-OH-2-Adm,H),(1-625,i-Bu,F-13,S,S,O,5-OH-2-Adm,H),(1-626,i-Bu,F-14,S,S,O,5-OH-2-Adm,H),(1-627,i-Bu,F-15,S,S,O,5-OH-2-Adm,H),(1-628,i-Bu,F-16,S,S,O,5-OH-2-Adm,H),(1-629,i-Bu,F-17,S,S,O,5-OH-2-Adm,H),(1-630,i-Bu,F-18,S,S,O,5-OH-2-Adm,H),(1-631,i-Bu,F-19,S,S,O,5-OH-2-Adm,H),(1-632,i-Bu,F-20,S,S,O,5-OH-2-Adm,H),(1-633,i-Bu,F-21,S,S,O,5-OH-2-Adm,H),(1-634,i-Bu,F-22,S,S,O,5-OH-2-Adm,H),(1-635,i-Bu,F-23,S,S,O,5-OH-2-Adm,H),(1-636,i-Bu,F-24,S,S,O,5-OH-2-Adm,H),(1-637,i-Bu,F-25,S,S,O,5-OH-2-Adm,H),(1-638,i-Bu,F-26,S,S,O,5-OH-2-Adm,H),(1-639,i-Bu,F-27,S,S,O,5-OH-2-Adm,H),(1-640,i-Bu,F-28,S,S,O,5-OH-2-Adm,H),(1-641,i-Bu,F-29,S,S,O,5-OH-2-Adm,H),(1-642,i-Bu,F-30,S,S,O,5-OH-2-Adm,H),(1-643,i-Bu,F-31,S,S,O,5-OH-2-Adm,H),(1-644,i-Bu,F-32,S,S,O,5-OH-2-Adm,H),(1-645,i-Bu,F-33,S,S,O,5-OH-2-Adm,H),(1-646,i-Bu,F-34,S,S,O,5-OH-2-Adm,H),(1-647,i-Bu,F-35,S,S,O,5-OH-2-Adm,H),(1-648,i-Bu,F-36,S,S,O,5-OH-2-Adm,H),(1-649,i-Bu,G-1,S,S,O,1-Adm,H),(1-650,i-Bu,G-2,S,S,O,1-Adm,H),(1-651,i-Bu,G-3,S,S,O,1-Adm,H),(1-652,i-Bu,G-4,S,S,O,1-Adm,H),(1-653,i-Bu,G-5,S,S,O,1-Adm,H),(1-654,i-Bu,G-6,S,S,O,1-Adm,H),(1-655,i-Bu,G-7,S,S,O,1-Adm,H),(1-656,i-Bu,G-8,S,S,O,1-Adm,H),(1-657,i-Bu,G-9,S,S,O,1-Adm,H),(1-658,i-Bu,G-1,S,S,O,2-Adm,H),(1-659,i-Bu,G-2,S,S,O,2-Adm,H),(1-660,i-Bu,G-3,S,S,O,2-Adm,H),(1-661,i-Bu,G-4,S,S,O,2-Adm,H),(1-662,i-Bu,G-5,S,S,O,2-Adm,H),(1-663,i-Bu,G-6,S,S,O,2-Adm,H),(1-664,i-Bu,G-7,S,S,O,2-Adm,H),(1-665,i-Bu,G-8,S,S,O,2-Adm,H),(1-666,i-Bu,G-9,S,S,O,2-Adm,H),(1-667,i-Bu,G-1,S,S,O,5-OH-2-Adm,H),(1-668,i-Bu,G-2,S,S,O,5-OH-2-Adm,H),(1-669,i-Bu,G-3,S,S,O,5-OH-2-Adm,H),(1-670,i-Bu,G-4,S,S,O,5-OH-2-Adm,H),(1-671,i-Bu,G-5,S,S,O,5-OH-2-Adm,H),(1-672,i-Bu,G-6,S,S,O,5-OH-2-Adm,H),(1-673,i-Bu,G-7,S,S,O,5-OH-2-Adm,H),(1-674,i-Bu,G-8,S,S,O,5-OH-2-Adm,H),(1-675,i-Bu,G-9,S,S,O,5-OH-2-Adm,H),(1-676,i-Bu,H-1,S,S,O,1-Adm,H),(1-677,i-Bu,H-2,S,S,O,1-Adm,H),(1-678,i-Bu,H-3,S,S,O,1-Adm,H),(1-679,i-Bu,H-4,S,S,O,1-Adm,H),(1-680,i-Bu,H-5,S,S,O,1-Adm,H),(1-681,i-Bu,H-6,S,S,O,1-Adm,H),(1-682,i-Bu,H-7,S,S,O,1-Adm,H),(1-683,i-Bu,H-8,S,S,O,1-Adm,H),(1-684,i-Bu,H-9,S,S,O,1-Adm,H),(1-685,i-Bu,H-1,S,S,O,2-Adm,H),(1-686,i-Bu,H-2,S,S,O,2-Adm,H),(1-687,i-Bu,H-3,S,S,O,2-Adm,H),(1-688,i-Bu,H-4,S,S,O,2-Adm,H),(1-689,i-Bu,H-5,S,S,O,2-Adm,H),(1-690,i-Bu,H-6,S,S,O,2-Adm,H),(1-691,i-Bu,H-7,S,S,O,2-Adm,H),(1-692,i-Bu,H-8,S,S,O,2-Adm,H),(1-693,i-Bu,H-9,S,S,O,2-Adm,H),(1-694,i-Bu,H-1,S,S,O,5-OH-2-Adm,H),(1-695,i-Bu,H-2,S,S,O,5-OH-2-Adm,H),(1-696,i-Bu,H-3,S,S,O,5-OH-2-Adm,H),(1-697,i-Bu,H-4,S,S,O,5-OH-2-Adm,H),(1-698,i-Bu,H-5,S,S,O,5-OH-2-Adm,H),(1-699,i-Bu,H-6,S,S,O,5-OH-2-Adm,H),(1-700,i-Bu,H-7,S,S,O,5-OH-2-Adm,H),(1-701,i-Bu,H-8,S,S,O,5-OH-2-Adm,H),(1-702,i-Bu,H-9,S,S,O,5-OH-2-Adm,H),(1-703,i-Bu,I-1,S,S,O,1-Adm,H),(1-704,i-Bu,I-2,S,S,O,1-Adm,H),(1-705,i-Bu,I-3,S,S,O,1-Adm,H),(1-706,i-Bu,I-4,S,S,O,1-Adm,H),(1-707,i-Bu,I-5,S,S,O,1-Adm,H),(1-708,i-Bu,I-6,S,S,O,1-Adm,H),(1-709,i-Bu,I-7,S,S,O,1-Adm,H),(1-710,i-Bu,I-8,S,S,O,1-Adm,H),(1-711,i-Bu,I-9,S,S,O,1-Adm,H),(1-712,i-Bu,I-1,S,S,O,2-Adm,H),(1-713,i-Bu,I-2,S,S,O,2-Adm,H),(1-714,i-Bu,I-3,S,S,O,2-Adm,H),(1-715,i-Bu,I-4,S,S,O,2-Adm,H),(1-716,i-Bu,I-5,S,S,O,2-Adm,H),(1-717,i-Bu,I-6,S,S,O,2-Adm,H),(1-718,i-Bu,I-7,S,S,O,2-Adm,H),(1-719,i-Bu,I-8,S,S,O,2-Adm,H),(1-720,i-Bu,I-9,S,S,O,2-Adm,H),(1-721,i-Bu,I-1,S,S,O,5-OH-2-Adm,H),(1-722,i-Bu,I-2,S,S,O,5-OH-2-Adm,H),(1-723,i-Bu,I-3,S,S,O,5-OH-2-Adm,H),(1-724,i-Bu,I-4,S,S,O,5-OH-2-Adm,H),(1-725,i-Bu,I-5,S,S,O,5-OH-2-Adm,H),(1-726,i-Bu,I-6,S,S,O,5-OH-2-Adm,H),(1-727,i-Bu,I-7,S,S,O,5-OH-2-Adm,H),(1-728,i-Bu,I-8,S,S,O,5-OH-2-Adm,H),(1-729,i-Bu,I-9,S,S,O,5-OH-2-Adm,H),(1-730,i-Bu,J-1,S,S,O,1-Adm,H),(1-731,i-Bu,J-2,S,S,O,1-Adm,H),(1-732,i-Bu,J-3,S,S,O,1-Adm,H),(1-733,i-Bu,J-4,S,S,O,1-Adm,H),(1-734,i-Bu,J-5,S,S,O,1-Adm,H),(1-735,i-Bu,J-6,S,S,O,1-Adm,H),(1-736,i-Bu,J-7,S,S,O,1-Adm,H),(1-737,i-Bu,J-8,S,S,O,1-Adm,H),(1-738,i-Bu,J-9,S,S,O,1-Adm,H),(1-739,i-Bu,J-1,S,S,O,2-Adm,H),(1-740,i-Bu,J-2,S,S,O,2-Adm,H),(1-741,i-Bu,J-3,S,S,O,2-Adm,H),(1-742,i-Bu,J-4,S,S,O,2-Adm,H),(1-743,i-Bu,J-5,S,S,O,2-Adm,H),(1-744,i-Bu,J-6,S,S,O,2-Adm,H),(1-745,i-Bu,J-7,S,S,O,2-Adm,H),(1-746,i-Bu,J-8,S,S,O,2-Adm,H),(1-747,i-Bu,J-9,S,S,O,2-Adm,H),(1-748,i-Bu,J-1,S,S,O,5-OH-2-Adm,H),(1-749,i-Bu,J-2,S,S,O,5-OH-2-Adm,H),(1-750,i-Bu,J-3,S,S,O,5-OH-2-Adm,H),(1-751,i-Bu,J-4,S,S,O,5-OH-2-Adm,H),(1-752,i-Bu,J-5,S,S,O,5-OH-2-Adm,H),(1-753,i-Bu,J-6,S,S,O,5-OH-2-Adm,H),(1-754,i-Bu,J-7,S,S,O,5-OH-2-Adm,H),(1-755,i-Bu,J-8,S,S,O,5-OH-2-Adm,H),(1-756,i-Bu,J-9,S,S,O,5-OH-2-Adm,H),(1-757,i-Bu,K-1,S,S,O,1-Adm,H),(1-758,i-Bu,K-2,S,S,O,1-Adm,H),(1-759,i-Bu,K-3,S,S,O,1-Adm,H),(1-760,i-Bu,K-4,S,S,O,1-Adm,H),(1-761,i-Bu,K-5,S,S,O,1-Adm,H),(1-762,i-Bu,K-6,S,S,O,1-Adm,H),(1-763,i-Bu,K-7,S,S,O,1-Adm,H),(1-764,i-Bu,K-8,S,S,O,1-Adm,H),(1-765,i-Bu,K-9,S,S,O,1-Adm,H),(1-766,i-Bu,K-1,S,S,O,2-Adm,H),(1-767,i-Bu,K-2,S,S,O,2-Adm,H),(1-768,i-Bu,K-3,S,S,O,2-Adm,H),(1-769,i-Bu,K-4,S,S,O,2-Adm,H),(1-770,i-Bu,K-5,S,S,O,2-Adm,H),(1-771,i-Bu,K-6,S,S,O,2-Adm,H),(1-772,i-Bu,K-7,S,S,O,2-Adm,H),(1-773,i-Bu,K-8,S,S,O,2-Adm,H),(1-774,i-Bu,K-9,S,S,O,2-Adm,H),(1-775,i-Bu,K-1,S,S,O,5-OH-2-Adm,H),(1-776,i-Bu,K-2,S,S,O,5-OH-2-Adm,H),(1-777,i-Bu,K-3,S,S,O,5-OH-2-Adm,H),(1-778,i-Bu,K-4,S,S,O,5-OH-2-Adm,H),(1-779,i-Bu,K-5,S,S,O,5-OH-2-Adm,H),(1-780,i-Bu,K-6,S,S,O,5-OH-2-Adm,H),(1-781,i-Bu,K-7,S,S,O,5-OH-2-Adm,H),(1-782,i-Bu,K-8,S,S,O,5-OH-2-Adm,H),(1-783,i-Bu,K-9,S,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(2-1,Pro,A-1,S,S,O,1-Adm,H),(2-2,Pro,A-2,S,S,O,1-Adm,H),(2-3,Pro,A-3,S,S,O,1-Adm,H),(2-4,Pro,A-4,S,S,O,1-Adm,H),(2-5,Pro,A-5,S,S,O,1-Adm,H),(2-6,Pro,A-6,S,S,O,1-Adm,H),(2-7,Pro,A-7,S,S,O,1-Adm,H),(2-8,Pro,A-8,S,S,O,1-Adm,H),(2-9,Pro,A-9,S,S,O,1-Adm,H),(2-10,Pro,A-10,S,S,O,1-Adm,H),(2-11,Pro,A-11,S,S,O,1-Adm,H),(2-12,Pro,A-12,S,S,O,1-Adm,H),(2-13,Pro,A-13,S,S,O,1-Adm,H),(2-14,Pro,A-14,S,S,O,1-Adm,H),(2-15,Pro,A-15,S,S,O,1-Adm,H),(2-16,Pro,A-16,S,S,O,1-Adm,H),(2-17,Pro,A-17,S,S,O,1-Adm,H),(2-18,Pro,A-18,S,S,O,1-Adm,H),(2-19,Pro,A-19,S,S,O,1-Adm,H),(2-20,Pro,A-20,S,S,O,1-Adm,H),(2-21,Pro,A-21,S,S,O,1-Adm,H),(2-22,Pro,A-22,S,S,O,1-Adm,H),(2-23,Pro,A-23,S,S,O,1-Adm,H),(2-24,Pro,A-24,S,S,O,1-Adm,H),(2-25,Pro,A-25,S,S,O,1-Adm,H),(2-26,Pro,A-26,S,S,O,1-Adm,H),(2-27,Pro,A-27,S,S,O,1-Adm,H),(2-28,Pro,A-28,S,S,O,1-Adm,H),(2-29,Pro,A-29,S,S,O,1-Adm,H),(2-30,Pro,A-30,S,S,O,1-Adm,H),(2-31,Pro,A-31,S,S,O,1-Adm,H),(2-32,Pro,A-32,S,S,O,1-Adm,H),(2-33,Pro,A-33,S,S,O,1-Adm,H),(2-34,Pro,A-34,S,S,O,1-Adm,H),(2-35,Pro,A-35,S,S,O,1-Adm,H),(2-36,Pro,A-36,S,S,O,1-Adm,H),(2-37,Pro,A-1,S,S,O,2-Adm,H),(2-38,Pro,A-2,S,S,O,2-Adm,H),(2-39,Pro,A-3,S,S,O,2-Adm,H),(2-40,Pro,A-4,S,S,O,2-Adm,H),(2-41,Pro,A-5,S,S,O,2-Adm,H),(2-42,Pro,A-6,S,S,O,2-Adm,H),(2-43,Pro,A-7,S,S,O,2-Adm,H),(2-44,Pro,A-8,S,S,O,2-Adm,H),(2-45,Pro,A-9,S,S,O,2-Adm,H),(2-46,Pro,A-1,S,S,O,2-Adm,H),(2-47,Pro,A-11,S,S,O,2-Adm,H),(2-48,Pro,A-12,S,S,O,2-Adm,H),(2-49,Pro,A-13,S,S,O,2-Adm,H),(2-50,Pro,A-14,S,S,O,2-Adm,H),(2-51,Pro,A-15,S,S,O,2-Adm,H),(2-52,Pro,A-16,S,S,O,2-Adm,H),(2-53,Pro,A-17,S,S,O,2-Adm,H),(2-54,Pro,A-18,S,S,O,2-Adm,H),(2-55,Pro,A-19,S,S,O,2-Adm,H),(2-56,Pro,A-20,S,S,O,2-Adm,H),(2-57,Pro,A-21,S,S,O,2-Adm,H),(2-58,Pro,A-22,S,S,O,2-Adm,H),(2-59,Pro,A-23,S,S,O,2-Adm,H),(2-60,Pro,A-24,S,S,O,2-Adm,H),(2-61,Pro,A-25,S,S,O,2-Adm,H),(2-62,Pro,A-26,S,S,O,2-Adm,H),(2-63,Pro,A-27,S,S,O,2-Adm,H),(2-64,Pro,A-28,S,S,O,2-Adm,H),(2-65,Pro,A-29,S,S,O,2-Adm,H),(2-66,Pro,A-30,S,S,O,2-Adm,H),(2-67,Pro,A-31,S,S,O,2-Adm,H),(2-68,Pro,A-32,S,S,O,2-Adm,H),(2-69,Pro,A-33,S,S,O,2-Adm,H),(2-70,Pro,A-34,S,S,O,2-Adm,H),(2-71,Pro,A-35,S,S,O,2-Adm,H),(2-72,Pro,A-36,S,S,O,2-Adm,H),(2-73,Pro,A-1,S,S,O,5-OH-2-Adm,H),(2-74,Pro,A-2,S,S,O,5-OH-2-Adm,H),(2-75,Pro,A-3,S,S,O,5-OH-2-Adm,H),(2-76,Pro,A-4,S,S,O,5-OH-2-Adm,H),(2-77,Pro,A-5,S,S,O,5-OH-2-Adm,H),(2-78,Pro,A-6,S,S,O,5-OH-2-Adm,H),(2-79,Pro,A-7,S,S,O,5-OH-2-Adm,H),(2-80,Pro,A-8,S,S,O,5-OH-2-Adm,H),(2-81,Pro,A-9,S,S,O,5-OH-2-Adm,H),(2-82,Pro,A-10,S,S,O,5-OH-2-Adm,H),(2-83,Pro,A-11,S,S,O,5-OH-2-Adm,H),(2-84,Pro,A-12,S,S,O,5-OH-2-Adm,H),(2-85,Pro,A-13,S,S,O,5-OH-2-Adm,H),(2-86,Pro,A-14,S,S,O,5-OH-2-Adm,H),(2-87,Pro,A-15,S,S,O,5-OH-2-Adm,H),(2-88,Pro,A-16,S,S,O,5-OH-2-Adm,H),(2-89,Pro,A-17,S,S,O,5-OH-2-Adm,H),(2-90,Pro,A-18,S,S,O,5-OH-2-Adm,H),(2-91,Pro,A-19,S,S,O,5-OH-2-Adm,H),(2-92,Pro,A-20,S,S,O,5-OH-2-Adm,H),(2-93,Pro,A-21,S,S,O,5-OH-2-Adm,H),(2-94,Pro,A-22,S,S,O,5-OH-2-Adm,H),(2-95,Pro,A-23,S,S,O,5-OH-2-Adm,H),(2-96,Pro,A-24,S,S,O,5-OH-2-Adm,H),(2-97,Pro,A-25,S,S,O,5-OH-2-Adm,H),(2-98,Pro,A-26,S,S,O,5-OH-2-Adm,H),(2-99,Pro,A-27,S,S,O,5-OH-2-Adm,H),(2-100,Pro,A-28,S,S,O,5-OH-2-Adm,H),(2-101,Pro,A-29,S,S,O,5-OH-2-Adm,H),(2-102,Pro,A-30,S,S,O,5-OH-2-Adm,H),(2-103,Pro,A-31,S,S,O,5-OH-2-Adm,H),(2-104,Pro,A-32,S,S,O,5-OH-2-Adm,H),(2-105,Pro,A-33,S,S,O,5-OH-2-Adm,H),(2-106,Pro,A-34,S,S,O,5-OH-2-Adm,H),(2-107,Pro,A-35,S,S,O,5-OH-2-Adm,H),(2-108,Pro,A-36,S,S,O,5-OH-2-Adm,H),(2-109,Pro,B-1,S,S,O,1-Adm,H),(2-110,Pro,B-2,S,S,O,1-Adm,H),(2-111,Pro,B-3,S,S,O,1-Adm,H),(2-112,Pro,B-4,S,S,O,1-Adm,H),(2-113,Pro,B-5,S,S,O,1-Adm,H),(2-114,Pro,B-6,S,S,O,1-Adm,H),(2-115,Pro,B-7,S,S,O,1-Adm,H),(2-116,Pro,B-8,S,S,O,1-Adm,H),(2-117,Pro,B-9,S,S,O,1-Adm,H),(2-118,Pro,B-11,S,S,O,1-Adm,H),(2-119,Pro,B-11,S,S,O,1-Adm,H),(2-120,Pro,B-12,S,S,O,1-Adm,H),(2-121,Pro,B-13,S,S,O,1-Adm,H),(2-122,Pro,B-14,S,S,O,1-Adm,H),(2-123,Pro,B-15,S,S,O,1-Adm,H),(2-124,Pro,B-16,S,S,O,1-Adm,H),(2-125,Pro,B-17,S,S,O,1-Adm,H),(2-126,Pro,B-18,S,S,O,1-Adm,H),(2-127,Pro,B-19,S,S,O,1-Adm,H),(2-128,Pro,B-20,S,S,O,1-Adm,H),(2-129,Pro,B-21,S,S,O,1-Adm,H),(2-130,Pro,B-22,S,S,O,1-Adm,H),(2-131,Pro,B-23,S,S,O,1-Adm,H),(2-132,Pro,B-24,S,S,O,1-Adm,H),(2-133,Pro,B-25,S,S,O,1-Adm,H),(2-134,Pro,B-26,S,S,O,1-Adm,H),(2-135,Pro,B-27,S,S,O,1-Adm,H),(2-136,Pro,B-28,S,S,O,1-Adm,H),(2-137,Pro,B-29,S,S,O,1-Adm,H),(2-138,Pro,B-30,S,S,O,1-Adm,H),(2-139,Pro,B-31,S,S,O,1-Adm,H),(2-140,Pro,B-32,S,S,O,1-Adm,H),(2-141,Pro,B-33,S,S,O,1-Adm,H),(2-142,Pro,B-34,S,S,O,1-Adm,H),(2-143,Pro,B-35,S,S,O,1-Adm,H),(2-144,Pro,B-36,S,S,O,1-Adm,H),(2-145,Pro,B-1,S,S,O,2-Adm,H),(2-146,Pro,B-2,S,S,O,2-Adm,H),(2-147,Pro,B-3,S,S,O,2-Adm,H),(2-148,Pro,B-4,S,S,O,2-Adm,H),(2-149,Pro,B-5,S,S,O,2-Adm,H),(2-150,Pro,B-6,S,S,O,2-Adm,H),(2-151,Pro,B-7,S,S,O,2-Adm,H),(2-152,Pro,B-8,S,S,O,2-Adm,H),(2-153,Pro,B-9,S,S,O,2-Adm,H),(2-154,Pro,B-10,S,S,O,2-Adm,H),(2-155,Pro,B-11,S,S,O,2-Adm,H),(2-156,Pro,B-12,S,S,O,2-Adm,H),(2-157,Pro,B-13,S,S,O,2-Adm,H),(2-158,Pro,B-14,S,S,O,2-Adm,H),(2-159,Pro,B-15,S,S,O,2-Adm,H),(2-160,Pro,B-16,S,S,O,2-Adm,H),(2-161,Pro,B-17,S,S,O,2-Adm,H),(2-162,Pro,B-18,S,S,O,2-Adm,H),(2-163,Pro,B-19,S,S,O,2-Adm,H),(2-164,Pro,B-20,S,S,O,2-Adm,H),(2-165,Pro,B-21,S,S,O,2-Adm,H),(2-166,Pro,B-22,S,S,O,2-Adm,H),(2-167,Pro,B-23,S,S,O,2-Adm,H),(2-168,Pro,B-24,S,S,O,2-Adm,H),(2-169,Pro,B-25,S,S,O,2-Adm,H),(2-170,Pro,B-26,S,S,O,2-Adm,H),(2-171,Pro,B-27,S,S,O,2-Adm,H),(2-172,Pro,B-28,S,S,O,2-Adm,H),(2-173,Pro,B-29,S,S,O,2-Adm,H),(2-174,Pro,B-30,S,S,O,2-Adm,H),(2-175,Pro,B-31,S,S,O,2-Adm,H),(2-176,Pro,B-32,S,S,O,2-Adm,H),(2-177,Pro,B-33,S,S,O,2-Adm,H),(2-178,Pro,B-34,S,S,O,2-Adm,H),(2-179,Pro,B-35,S,S,O,2-Adm,H),(2-180,Pro,B-36,S,S,O,2-Adm,H),(2-181,Pro,B-1,S,S,O,5-OH-2-Adm,H),(2-182,Pro,B-2,S,S,O,5-OH-2-Adm,H),(2-183,Pro,B-3,S,S,O,5-OH-2-Adm,H),(2-184,Pro,B-4,S,S,O,5-OH-2-Adm,H),(2-185,Pro,B-5,S,S,O,5-OH-2-Adm,H),(2-186,Pro,B-6,S,S,O,5-OH-2-Adm,H),(2-187,Pro,B-7,S,S,O,5-OH-2-Adm,H),(2-188,Pro,B-8,S,S,O,5-OH-2-Adm,H),(2-189,Pro,B-9,S,S,O,5-OH-2-Adm,H),(2-190,Pro,B-10,S,S,O,5-OH-2-Adm,H),(2-191,Pro,B-11,S,S,O,5-OH-2-Adm,H),(2-192,Pro,B-12,S,S,O,5-OH-2-Adm,H),(2-193,Pro,B-13,S,S,O,5-OH-2-Adm,H),(2-194,Pro,B-14,S,S,O,5-OH-2-Adm,H),(2-195,Pro,B-15,S,S,O,5-OH-2-Adm,H),(2-196,Pro,B-16,S,S,O,5-OH-2-Adm,H),(2-197,Pro,B-17,S,S,O,5-OH-2-Adm,H),(2-198,Pro,B-18,S,S,O,5-OH-2-Adm,H),(2-199,Pro,B-19,S,S,O,5-OH-2-Adm,H),(2-200,Pro,B-20,S,S,O,5-OH-2-Adm,H),(2-201,Pro,B-21,S,S,O,5-OH-2-Adm,H),(2-202,Pro,B-22,S,S,O,5-OH-2-Adm,H),(2-203,Pro,B-23,S,S,O,5-OH-2-Adm,H),(2-204,Pro,B-24,S,S,O,5-OH-2-Adm,H),(2-205,Pro,B-25,S,S,O,5-OH-2-Adm,H),(2-206,Pro,B-26,S,S,O,5-OH-2-Adm,H),(2-207,Pro,B-27,S,S,O,5-OH-2-Adm,H),(2-208,Pro,B-28,S,S,O,5-OH-2-Adm,H),(2-209,Pro,B-29,S,S,O,5-OH-2-Adm,H),(2-210,Pro,B-30,S,S,O,5-OH-2-Adm,H),(2-211,Pro,B-31,S,S,O,5-OH-2-Adm,H),(2-212,Pro,B-32,S,S,O,5-OH-2-Adm,H),(2-213,Pro,B-33,S,S,O,5-OH-2-Adm,H),(2-214,Pro,B-34,S,S,O,5-OH-2-Adm,H),(2-215,Pro,B-35,S,S,O,5-OH-2-Adm,H),(2-216,Pro,B-36,S,S,O,5-OH-2-Adm,H),(2-217,Pro,C-1,S,S,O,1-Adm,H),(2-218,Pro,C-2,S,S,O,1-Adm,H),(2-219,Pro,C-3,S,S,O,1-Adm,H),(2-220,Pro,C-4,S,S,O,1-Adm,H),(2-221,Pro,C-5,S,S,O,1-Adm,H),(2-222,Pro,C-6,S,S,O,1-Adm,H),(2-223,Pro,C-7,S,S,O,1-Adm,H),(2-224,Pro,C-8,S,S,O,1-Adm,H),(2-225,Pro,C-9,S,S,O,1-Adm,H),(2-226,Pro,C-10,S,S,O,1-Adm,H),(2-227,Pro,C-11,S,S,O,1-Adm,H),(2-228,Pro,C-12,S,S,O,1-Adm,H),(2-229,Pro,C-13,S,S,O,1-Adm,H),(2-230,Pro,C-14,S,S,O,1-Adm,H),(2-231,Pro,C-15,S,S,O,1-Adm,H),(2-232,Pro,C-16,S,S,O,1-Adm,H),(2-233,Pro,C-17,S,S,O,1-Adm,H),(2-234,Pro,C-18,S,S,O,1-Adm,H),(2-235,Pro,C-19,S,S,O,1-Adm,H),(2-236,Pro,C-20,S,S,O,1-Adm,H),(2-237,Pro,C-21,S,S,O,1-Adm,H),(2-238,Pro,C-22,S,S,O,1-Adm,H),(2-239,Pro,C-23,S,S,O,1-Adm,H),(2-240,Pro,C-24,S,S,O,1-Adm,H),(2-241,Pro,C-25,S,S,O,1-Adm,H),(2-242,Pro,C-26,S,S,O,1-Adm,H),(2-243,Pro,C-27,S,S,O,1-Adm,H),(2-244,Pro,C-28,S,S,O,1-Adm,H),(2-245,Pro,C-29,S,S,O,1-Adm,H),(2-246,Pro,C-30,S,S,O,1-Adm,H),(2-247,Pro,C-31,S,S,O,1-Adm,H),(2-248,Pro,C-32,S,S,O,1-Adm,H),(2-249,Pro,C-33,S,S,O,1-Adm,H),(2-250,Pro,C-34,S,S,O,1-Adm,H),(2-251,Pro,C-35,S,S,O,1-Adm,H),(2-252,Pro,C-36,S,S,O,1-Adm,H),(2-253,Pro,C-1,S,S,O,2-Adm,H),(2-254,Pro,C-2,S,S,O,2-Adm,H),(2-255,Pro,C-3,S,S,O,2-Adm,H),(2-256,Pro,C-4,S,S,O,2-Adm,H),(2-257,Pro,C-5,S,S,O,2-Adm,H),(2-258,Pro,C-6,S,S,O,2-Adm,H),(2-259,Pro,C-7,S,S,O,2-Adm,H),(2-260,Pro,C-8,S,S,O,2-Adm,H),(2-261,Pro,C-9,S,S,O,2-Adm,H),(2-262,Pro,C-11,S,S,O,2-Adm,H),(2-263,Pro,C-11,S,S,O,2-Adm,H),(2-264,Pro,C-12,S,S,O,2-Adm,H),(2-265,Pro,C-13,S,S,O,2-Adm,H),(2-266,Pro,C-14,S,S,O,2-Adm,H),(2-267,Pro,C-15,S,S,O,2-Adm,H),(2-268,Pro,C-16,S,S,O,2-Adm,H),(2-269,Pro,C-17,S,S,O,2-Adm,H),(2-270,Pro,C-18,S,S,O,2-Adm,H),(2-271,Pro,C-19,S,S,O,2-Adm,H),(2-272,Pro,C-20,S,S,O,2-Adm,H),(2-273,Pro,C-21,S,S,O,2-Adm,H),(2-274,Pro,C-22,S,S,O,2-Adm,H),(2-275,Pro,C-23,S,S,O,2-Adm,H),(2-276,Pro,C-24,S,S,O,2-Adm,H),(2-277,Pro,C-25,S,S,O,2-Adm,H),(2-278,Pro,C-26,S,S,O,2-Adm,H),(2-279,Pro,C-27,S,S,O,2-Adm,H),(2-280,Pro,C-28,S,S,O,2-Adm,H),(2-281,Pro,C-29,S,S,O,2-Adm,H),(2-282,Pro,C-30,S,S,O,2-Adm,H),(2-283,Pro,C-31,S,S,O,2-Adm,H),(2-284,Pro,C-32,S,S,O,2-Adm,H),(2-285,Pro,C-33,S,S,O,2-Adm,H),(2-286,Pro,C-34,S,S,O,2-Adm,H),(2-287,Pro,C-35,S,S,O,2-Adm,H),(2-288,Pro,C-36,S,S,O,2-Adm,H),(2-289,Pro,C-1,S,S,O,5-OH-2-Adm,H),(2-290,Pro,C-2,S,S,O,5-OH-2-Adm,H),(2-291,Pro,C-3,S,S,O,5-OH-2-Adm,H),(2-292,Pro,C-4,S,S,O,5-OH-2-Adm,H),(2-293,Pro,C-5,S,S,O,5-OH-2-Adm,H),(2-294,Pro,C-6,S,S,O,5-OH-2-Adm,H),(2-295,Pro,C-7,S,S,O,5-OH-2-Adm,H),(2-296,Pro,C-8,S,S,O,5-OH-2-Adm,H),(2-297,Pro,C-9,S,S,O,5-OH-2-Adm,H),(2-298,Pro,C-10,S,S,O,5-OH-2-Adm,H),(2-299,Pro,C-11,S,S,O,5-OH-2-Adm,H),(2-300,Pro,C-12,S,S,O,5-OH-2-Adm,H),(2-301,Pro,C-13,S,S,O,5-OH-2-Adm,H),(2-302,Pro,C-14,S,S,O,5-OH-2-Adm,H),(2-303,Pro,C-15,S,S,O,5-OH-2-Adm,H),(2-304,Pro,C-16,S,S,O,5-OH-2-Adm,H),(2-305,Pro,C-17,S,S,O,5-OH-2-Adm,H),(2-306,Pro,C-18,S,S,O,5-OH-2-Adm,H),(2-307,Pro,C-19,S,S,O,5-OH-2-Adm,H),(2-308,Pro,C-20,S,S,O,5-OH-2-Adm,H),(2-309,Pro,C-21,S,S,O,5-OH-2-Adm,H),(2-310,Pro,C-22,S,S,O,5-OH-2-Adm,H),(2-311,Pro,C-23,S,S,O,5-OH-2-Adm,H),(2-312,Pro,C-24,S,S,O,5-OH-2-Adm,H),(2-313,Pro,C-25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,(2-468,Pro,E-36,S,S,O,1-Adm,H),(2-469,Pro,E-1,S,S,O,2-Adm,H),(2-470,Pro,E-2,S,S,O,2-Adm,H),(2-471,Pro,E-3,S,S,O,2-Adm,H),(2-472,Pro,E-4,S,S,O,2-Adm,H),(2-473,Pro,E-5,S,S,O,2-Adm,H),(2-474,Pro,E-6,S,S,O,2-Adm,H),(2-475,Pro,E-7,S,S,O,2-Adm,H),(2-476,Pro,E-8,S,S,O,2-Adm,H),(2-477,Pro,E-9,S,S,O,2-Adm,H),(2-478,Pro,E-110,S,S,O,2-Adm,H),(2-479,Pro,E-111,S,S,O,2-Adm,H),(2-480,Pro,E-12,S,S,O,2-Adm,H),(2-481,Pro,E-13,S,S,O,2-Adm,H),(2-482,Pro,E-14,S,S,O,2-Adm,H),(2-483,Pro,E-11,S,S,O,2-Adm,H),(2-484,Pro,E-16,S,S,O,2-Adm,H),(2-485,Pro,E-17,S,S,O,2-Adm,H),(2-486,Pro,E-18,S,S,O,2-Adm,H),(2-487,Pro,E-119,S,S,O,2-Adm,H),(2-488,Pro,E-20,S,S,O,2-Adm,H),(2-489,Pro,E-21,S,S,O,2-Adm,H),(2-490,Pro,E-22,S,S,O,2-Adm,H),(2-491,Pro,E-23,S,S,O,2-Adm,H),(2-492,Pro,E-24,S,S,O,2-Adm,H),(2-493,Pro,E-25,S,S,O,2-Adm,H),(2-494,Pro,E-26,S,S,O,2-Adm,H),(2-495,Pro,E-27,S,S,O,2-Adm,H),(2-496,Pro,E-28,S,S,O,2-Adm,H),(2-497,Pro,E-29,S,S,O,2-Adm,H),(2-498,Pro,E-30,S,S,O,2-Adm,H),(2-499,Pro,E-31,S,S,O,2-Adm,H),(2-500,Pro,E-32,S,S,O,2-Adm,H),(2-501,Pro,E-33,S,S,O,2-Adm,H),(2-502,Pro,E-34,S,S,O,2-Adm,H),(2-503,Pro,E-35,S,S,O,2-Adm,H),(2-504,Pro,E-36,S,S,O,2-Adm,H),(2-505,Pro,E-1,S,S,O,5-OH-2-Adm,H),(2-506,Pro,E-2,S,S,O,5-OH-2-Adm,H),(2-507,Pro,E-3,S,S,O,5-OH-2-Adm,H),(2-508,Pro,E-4,S,S,O,5-OH-2-Adm,H),(2-509,Pro,E-5,S,S,O,5-OH-2-Adm,H),(2-510,Pro,E-6,S,S,O,5-OH-2-Adm,H),(2-511,Pro,E-7,S,S,O,5-OH-2-Adm,H),(2-512,Pro,E-8,S,S,O,5-OH-2-Adm,H),(2-513,Pro,E-9,S,S,O,5-OH-2-Adm,H),(2-514,Pro,E-10,S,S,O,5-OH-2-Adm,H),(2-515,Pro,E-11,S,S,O,5-OH-2-Adm,H),(2-516,Pro,E-12,S,S,O,5-OH-2-Adm,H),(2-517,Pro,E-13,S,S,O,5-OH-2-Adm,H),(2-518,Pro,E-14,S,S,O,5-OH-2-Adm,H),(2-519,Pro,E-15,S,S,O,5-OH-2-Adm,H),(2-520,Pro,E-16,S,S,O,5-OH-2-Adm,H),(2-521,Pro,E-17,S,S,O,5-OH-2-Adm,H),(2-522,Pro,E-18,S,S,O,5-OH-2-Adm,H),(2-523,Pro,E-19,S,S,O,5-OH-2-Adm,H),(2-524,Pro,E-20,S,S,O,5-OH-2-Adm,H),(2-525,Pro,E-21,S,S,O,5-OH-2-Adm,H),(2-526,Pro,E-22,S,S,O,5-OH-2-Adm,H),(2-527,Pro,E-23,S,S,O,5-OH-2-Adm,H),(2-528,Pro,E-24,S,S,O,5-OH-2-Adm,H),(2-529,Pro,E-25,S,S,O,5-OH-2-Adm,H),(2-530,Pro,E-26,S,S,O,5-OH-2-Adm,H),(2-531,Pro,E-27,S,S,O,5-OH-2-Adm,H),(2-532,Pro,E-28,S,S,O,5-OH-2-Adm,H),(2-533,Pro,E-29,S,S,O,5-OH-2-Adm,H),(2-534,Pro,E-30,S,S,O,5-OH-2-Adm,H),(2-535,Pro,E-31,S,S,O,5-OH-2-Adm,H),(2-536,Pro,E-32,S,S,O,5-OH-2-Adm,H),(2-537,Pro,E-33,S,S,O,5-OH-2-Adm,H),(2-538,Pro,E-34,S,S,O,5-OH-2-Adm,H),(2-539,Pro,E-35,S,S,O,5-OH-2-Adm,H),(2-540,Pro,E-36,S,S,O,5-OH-2-Adm,H),(2-541,Pro,F-1,S,S,O,1-Adm,H),(2-542,Pro,F-2,S,S,O,1-Adm,H),(2-543,Pro,F-3,S,S,O,1-Adm,H),(2-544,Pro,F-4,S,S,O,1-Adm,H),(2-545,Pro,F-5,S,S,O,1-Adm,H),(2-546,Pro,F-6,S,S,O,1-Adm,H),(2-547,Pro,F-7,S,S,O,1-Adm,H),(2-548,Pro,F-8,S,S,O,1-Adm,H),(2-549,Pro,F-9,S,S,O,1-Adm,H),(2-550,Pro,F-110,S,S,O,1-Adm,H),(2-551,Pro,F-111,S,S,O,1-Adm,H),(2-552,Pro,F-12,S,S,O,1-Adm,H),(2-553,Pro,F-13,S,S,O,1-Adm,H),(2-554,Pro,F-14,S,S,O,1-Adm,H),(2-555,Pro,F-15,S,S,O,1-Adm,H),(2-556,Pro,F-16,S,S,O,1-Adm,H),(2-557,Pro,F-17,S,S,O,1-Adm,H),(2-558,Pro,F-18,S,S,O,1-Adm,H),(2-559,Pro,F-19,S,S,O,1-Adm,H),(2-560,Pro,F-20,S,S,O,1-Adm,H),(2-561,Pro,F-21,S,S,O,1-Adm,H),(2-562,Pro,F-22,S,S,O,1-Adm,H),(2-563,Pro,F-23,S,S,O,1-Adm,H),(2-564,Pro,F-24,S,S,O,1-Adm,H),(2-565,Pro,F-25,S,S,O,1-Adm,H),(2-566,Pro,F-26,S,S,O,1-Adm,H),(2-567,Pro,F-27,S,S,O,1-Adm,H),(2-568,Pro,F-28,S,S,O,11-Adm,H),(2-569,Pro,F-29,S,S,O,1-Adm,H),(2-570,Pro,F-30,S,S,O,1-Adm,H),(2-571,Pro,F-31,S,S,O,1-Adm,H),(2-572,Pro,F-32,S,S,O,1-Adm,H),(2-573,Pro,F-33,S,S,O,1-Adm,H),(2-574,Pro,F-34,S,S,O,1-Adm,H),(2-575,Pro,F-35,S,S,O,11-Adm,H),(2-576,Pro,F-36,S,S,O,1-Adm,H),(2-577,Pro,F-1,S,S,O,2-Adm,H),(2-578,Pro,F-2,S,S,O,2-Adm,H),(2-579,Pro,F-3,S,S,O,2-Adm,H),(2-580,Pro,F-4,S,S,O,2-Adm,H),(2-581,Pro,F-5,S,S,O,2-Adm,H),(2-582,Pro,F-6,S,S,O,2-Adm,H),(2-583,Pro,F-7,S,S,O,2-Adm,H),(2-584,Pro,F-8,S,S,O,2-Adm,H),(2-585,Pro,F-9,S,S,O,2-Adm,H),(2-586,Pro,F-10,S,S,O,2-Adm,H),(2-587,Pro,F-111,S,S,O,2-Adm,H),(2-588,Pro,F-12,S,S,O,2-Adm,H),(2-589,Pro,F-13,S,S,O,2-Adm,H),(2-590,Pro,F-14,S,S,O,2-Adm,H),(2-591,Pro,F-11,S,S,O,2-Adm,H),(2-592,Pro,F-16,S,S,O,2-Adm,H),(2-593,Pro,F-17,S,S,O,2-Adm,H),(2-594,Pro,F-18,S,S,O,2-Adm,H),(2-595,Pro,F-19,S,S,O,2-Adm,H),(2-596,Pro,F-20,S,S,O,2-Adm,H),(2-597,Pro,F-21,S,S,O,2-Adm,H),(2-598,Pro,F-22,S,S,O,2-Adm,H),(2-599,Pro,F-23,S,S,O,2-Adm,H),(2-600,Pro,F-24,S,S,O,2-Adm,H),(2-601,Pro,F-25,S,S,O,2-Adm,H),(2-602,Pro,F-26,S,S,O,2-Adm,H),(2-603,Pro,F-27,S,S,O,2-Adm,H),(2-604,Pro,F-28,S,S,O,2-Adm,H),(2-605,Pro,F-29,S,S,O,2-Adm,H),(2-606,Pro,F-30,S,S,O,2-Adm,H),(2-607,Pro,F-31,S,S,O,2-Adm,H),(2-608,Pro,F-32,S,S,O,2-Adm,H),(2-609,Pro,F-33,S,S,O,2-Adm,H),(2-610,Pro,F-34,S,S,O,2-Adm,H),(2-611,Pro,F-35,S,S,O,2-Adm,H),(2-612,Pro,F-36,S,S,O,2-Adm,H),(2-613,Pro,F-1,S,S,O,5-OH-2-Adm,H),(2-614,Pro,F-2,S,S,O,5-OH-2-Adm,H),(2-615,Pro,F-3,S,S,O,5-OH-2-Adm,H),(2-616,Pro,F-4,S,S,O,5-OH-2-Adm,H),(2-617,Pro,F-5,S,S,O,5-OH-2-Adm,H),(2-618,Pro,F-6,S,S,O,5-OH-2-Adm,H),(2-619,Pro,F-7,S,S,O,5-OH-2-Adm,H),(2-620,Pro,F-8,S,S,O,5-OH-2-Adm,H),(2-621,Pro,F-9,S,S,O,5-OH-2-Adm,H),(2-622,Pro,F-10,S,S,O,5-OH-2-Adm,H),(2-623,Pro,F-11,S,S,O,5-OH-2-Adm,H),(2-624,Pro,F-12,S,S,O,5-OH-2-Adm,H),(2-625,Pro,F-13,S,S,O,5-OH-2-Adm,H),(2-626,Pro,F-14,S,S,O,5-OH-2-Adm,H),(2-627,Pro,F-15,S,S,O,5-OH-2-Adm,H),(2-628,Pro,F-16,S,S,O,5-OH-2-Adm,H),(2-629,Pro,F-17,S,S,O,5-OH-2-Adm,H),(2-630,Pro,F-18,S,S,O,5-OH-2-Adm,H),(2-631,Pro,F-19,S,S,O,5-OH-2-Adm,H),(2-632,Pro,F-20,S,S,O,5-OH-2-Adm,H),(2-633,Pro,F-21,S,S,O,5-OH-2-Adm,H),(2-634,Pro,F-22,S,S,O,5-OH-2-Adm,H),(2-635,Pro,F-23,S,S,O,5-OH-2-Adm,H),(2-636,Pro,F-24,S,S,O,5-OH-2-Adm,H),(2-637,Pro,F-25,S,S,O,5-OH-2-Adm,H),(2-638,Pro,F-26,S,S,O,5-OH-2-Adm,H),(2-639,Pro,F-27,S,S,O,5-OH-2-Adm,H),(2-640,Pro,F-28,S,S,O,5-OH-2-Adm,H),(2-641,Pro,F-29,S,S,O,5-OH-2-Adm,H),(2-642,Pro,F-30,S,S,O,5-OH-2-Adm,H),(2-643,Pro,F-31,S,S,O,5-OH-2-Adm,H),(2-644,Pro,F-32,S,S,O,5-OH-2-Adm,H),(2-645,Pro,F-33,S,S,O,5-OH-2-Adm,H),(2-646,Pro,F-34,S,S,O,5-OH-2-Adm,H),(2-647,Pro,F-35,S,S,O,5-OH-2-Adm,H),(2-648,Pro,F-36,S,S,O,5-OH-2-Adm,H),(2-649,Pro,G-1,S,S,O,1-Adm,H),(2-650,Pro,G-2,S,S,O,1-Adm,H),(2-651,Pro,G-3,S,S,O,1-Adm,H),(2-652,Pro,G-4,S,S,O,1-Adm,H),(2-653,Pro,G-5,S,S,O,1-Adm,H),(2-654,Pro,G-6,S,S,O,1-Adm,H),(2-655,Pro,G-7,S,S,O,1-Adm,H),(2-656,Pro,G-8,S,S,O,1-Adm,H),(2-657,Pro,G-9,S,S,O,1-Adm,H),(2-658,Pro,G-1,S,S,O,2-Adm,H),(2-659,Pro,G-2,S,S,O,2-Adm,H),(2-660,Pro,G-3,S,S,O,2-Adm,H),(2-661,Pro,G-4,S,S,O,2-Adm,H),(2-662,Pro,G-5,S,S,O,2-Adm,H),(2-663,Pro,G-6,S,S,O,2-Adm,H),(2-664,Pro,G-7,S,S,O,2-Adm,H),(2-665,Pro,G-8,S,S,O,2-Adm,H),(2-666,Pro,G-9,S,S,O,2-Adm,H),(2-667,Pro,G-1,S,S,O,5-OH-2-Adm,H),(2-668,Pro,G-2,S,S,O,5-OH-2-Adm,H),(2-669,Pro,G-3,S,S,O,5-OH-2-Adm,H),(2-670,Pro,G-4,S,S,O,5-OH-2-Adm,H),(2-671,Pro,G-5,S,S,O,5-OH-2-Adm,H),(2-672,Pro,G-6,S,S,O,5-OH-2-Adm,H),(2-673,Pro,G-7,S,S,O,5-OH-2-Adm,H),(2-674,Pro,G-8,S,S,O,5-OH-2-Adm,H),(2-675,Pro,G-9,S,S,O,5-OH-2-Adm,H),(2-676,Pro,H-1,S,S,O,1-Adm,H),(2-677,Pro,H-2,S,S,O,1-Adm,H),(2-678,Pro,H-3,S,S,O,1-Adm,H),(2-679,Pro,H-4,S,S,O,1-Adm,H),(2-680,Pro,H-5,S,S,O,1-Adm,H),(2-681,Pro,H-6,S,S,O,1-Adm,H),(2-682,Pro,H-7,S,S,O,1-Adm,H),(2-683,Pro,H-8,S,S,O,1-Adm,H),(2-684,Pro,H-9,S,S,O,1-Adm,H),(2-685,Pro,H-1,S,S,O,2-Adm,H),(2-686,Pro,H-2,S,S,O,2-Adm,H),(2-687,Pro,H-3,S,S,O,2-Adm,H),(2-688,Pro,H-4,S,S,O,2-Adm,H),(2-689,Pro,H-5,S,S,O,2-Adm,H),(2-690,Pro,H-6,S,S,O,2-Adm,H),(2-691,Pro,H-7,S,S,O,2-Adm,H),(2-692,Pro,H-8,S,S,O,2-Adm,H),(2-693,Pro,H-9,S,S,O,2-Adm,H),(2-694,Pro,H-1,S,S,O,5-OH-2-Adm,H),(2-695,Pro,H-2,S,S,O,5-OH-2-Adm,H),(2-696,Pro,H-3,S,S,O,5-OH-2-Adm,H),(2-697,Pro,H-4,S,S,O,5-OH-2-Adm,H),(2-698,Pro,H-5,S,S,O,5-OH-2-Adm,H),(2-699,Pro,H-6,S,S,O,5-OH-2-Adm,H),(2-700,Pro,H-7,S,S,O,5-OH-2-Adm,H),(2-701,Pro,H-8,S,S,O,5-OH-2-Adm,H),(2-702,Pro,H-9,S,S,O,5-OH-2-Adm,H),(2-703,Pro,I-1,S,S,O,1-Adm,H),(2-704,Pro,I-2,S,S,O,1-Adm,H),(2-705,Pro,I-3,S,S,O,1-Adm,H),(2-706,Pro,I-4,S,S,O,1-Adm,H),(2-707,Pro,I-5,S,S,O,1-Adm,H),(2-708,Pro,I-6,S,S,O,1-Adm,H),(2-709,Pro,I-7,S,S,O,1-Adm,H),(2-710,Pro,I-8,S,S,O,1-Adm,H),(2-711,Pro,I-9,S,S,O,1-Adm,H),(2-712,Pro,I-1,S,S,O,2-Adm,H),(2-713,Pro,I-2,S,S,O,2-Adm,H),(2-714,Pro,I-3,S,S,O,2-Adm,H),(2-715,Pro,I-4,S,S,O,2-Adm,H),(2-716,Pro,I-5,S,S,O,2-Adm,H),(2-717,Pro,I-6,S,S,O,2-Adm,H),(2-718,Pro,I-7,S,S,O,2-Adm,H),(2-719,Pro,I-8,S,S,O,2-Adm,H),(2-720,Pro,I-9,S,S,O,2-Adm,H),(2-721,Pro,I-1,S,S,O,5-OH-2-Adm,H),(2-722,Pro,I-2,S,S,O,5-OH-2-Adm,H),(2-723,Pro,I-3,S,S,O,5-OH-2-Adm,H),(2-724,Pro,I-4,S,S,O,5-OH-2-Adm,H),(2-725,Pro,I-5,S,S,O,5-OH-2-Adm,H),(2-726,Pro,I-6,S,S,O,5-OH-2-Adm,H),(2-727,Pro,I-7,S,S,O,5-OH-2-Adm,H),(2-728,Pro,I-8,S,S,O,5-OH-2-Adm,H),(2-729,Pro,I-9,S,S,O,5-OH-2-Adm,H),(2-730,Pro,J-1,S,S,O,1-Adm,H),(2-731,Pro,J-2,S,S,O,1-Adm,H),(2-732,Pro,J-3,S,S,O,1-Adm,H),(2-733,Pro,J-4,S,S,O,1-Adm,H),(2-734,Pro,J-5,S,S,O,1-Adm,H),(2-735,Pro,J-6,S,S,O,1-Adm,H),(2-736,Pro,J-7,S,S,O,1-Adm,H),(2-737,Pro,J-8,S,S,O,1-Adm,H),(2-738,Pro,J-9,S,S,O,1-Adm,H),(2-739,Pro,J-1,S,S,O,2-Adm,H),(2-740,Pro,J-2,S,S,O,2-Adm,H),(2-741,Pro,J-3,S,S,O,2-Adm,H),(2-742,Pro,J-4,S,S,O,2-Adm,H),(2-743,Pro,J-5,S,S,O,2-Adm,H),(2-744,Pro,J-6,S,S,O,2-Adm,H),(2-745,Pro,J-7,S,S,O,2-Adm,H),(2-746,Pro,J-8,S,S,O,2-Adm,H),(2-747,Pro,J-9,S,S,O,2-Adm,H),(2-748,Pro,J-1,S,S,O,5-OH-2-Adm,H),(2-749,Pro,J-2,S,S,O,5-OH-2-Adm,H),(2-750,Pro,J-3,S,S,O,5-OH-2-Adm,H),(2-751,Pro,J-4,S,S,O,5-OH-2-Adm,H),(2-752,Pro,J-5,S,S,O,5-OH-2-Adm,H),(2-753,Pro,J-6,S,S,O,5-OH-2-Adm,H),(2-754,Pro,J-7,S,S,O,5-OH-2-Adm,H),(2-755,Pro,J-8,S,S,O,5-OH-2-Adm,H),(2-756,Pro,J-9,S,S,O,5-OH-2-Adm,H),(2-757,Pro,K-1,S,S,O,1-Adm,H),(2-758,Pro,K-2,S,S,O,1-Adm,H),(2-759,Pro,K-3,S,S,O,1-Adm,H),(2-760,Pro,K-4,S,S,O,1-Adm,H),(2-761,Pro,K-5,S,S,O,1-Adm,H),(2-762,Pro,K-6,S,S,O,1-Adm,H),(2-763,Pro,K-7,S,S,O,1-Adm,H),(2-764,Pro,K-8,S,S,O,1-Adm,H),(2-765,Pro,K-9,S,S,O,1-Adm,H),(2-766,Pro,K-1,S,S,O,2-Adm,H),(2-767,Pro,K-2,S,S,O,2-Adm,H),(2-768,Pro,K-3,S,S,O,2-Adm,H),(2-769,Pro,K-4,S,S,O,2-Adm,H),(2-770,Pro,K-5,S,S,O,2-Adm,H),(2-771,Pro,K-6,S,S,O,2-Adm,H),(2-772,Pro,K-7,S,S,O,2-Adm,H),(2-773,Pro,K-8,S,S,O,2-Adm,H),(2-774,Pro,K-9,S,S,O,2-Adm,H),(2-775,Pro,K-1,S,S,O,5-OH-2-Adm,H),(2-776,Pro,K-2,S,S,O,5-OH-2-Adm,H),(2-777,Pro,K-3,S,S,O,5-OH-2-Adm,H),(2-778,Pro,K-4,S,S,O,5-OH-2-Adm,H),(2-779,Pro,K-5,S,S,O,5-OH-2-Adm,H),(2-780,Pro,K-6,S,S,O,5-OH-2-Adm,H),(2-781,Pro,K-7,S,S,O,5-OH-2-Adm,H),(2-782,Pro,K-8,S,S,O,5-OH-2-Adm,H),(2-783,Pro,K-9,S,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(3-1,i-Pro,A-1,S,S,O,1-Adm,H),(3-2,i-Pro,A-2,S,S,O,1-Adm,H),(3-3,i-Pro,A-3,S,S,O,1-Adm,H),(3-4,i-Pro,A-4,S,S,O,1-Adm,H),(3-5,i-Pro,A-5,S,S,O,1-Adm,H),(3-6,i-Pro,A-6,S,S,O,1-Adm,H),(3-7,i-Pro,A-7,S,S,O,1-Adm,H),(3-8,i-Pro,A-8,S,S,O,1-Adm,H),(3-9,i-Pro,A-9,S,S,O,1-Adm,H),(3-10,i-Pro,A-10,S,S,O,1-Adm,H),(3-11,i-Pro,A-11,S,S,O,1-Adm,H),(3-12,i-Pro,A-12,S,S,O,1-Adm,H),(3-13,i-Pro,A-13,S,S,O,1-Adm,H),(3-14,i-Pro,A-14,S,S,O,1-Adm,H),(3-15,i-Pro,A-15,S,S,O,1-Adm,H),(3-16,i-Pro,A-16,S,S,O,1-Adm,H),(3-17,i-Pro,A-17,S,S,O,1-Adm,H),(3-18,i-Pro,A-18,S,S,O,1-Adm,H),(3-19,i-Pro,A-19,S,S,O,1-Adm,H),(3-20,i-Pro,A-20,S,S,O,1-Adm,H),(3-21,i-Pro,A-21,S,S,O,1-Adm,H),(3-22,i-Pro,A-22,S,S,O,1-Adm,H),(3-23,i-Pro,A-23,S,S,O,1-Adm,H),(3-24,i-Pro,A-24,S,S,O,1-Adm,H),(3-25,i-Pro,A-25,S,S,O,1-Adm,H),(3-26,i-Pro,A-26,S,S,O,1-Adm,H),(3-27,i-Pro,A-27,S,S,O,1-Adm,H),(3-28,i-Pro,A-28,S,S,O,1-Adm,H),(3-29,i-Pro,A-29,S,S,O,1-Adm,H),(3-30,i-Pro,A-30,S,S,O,1-Adm,H),(3-31,i-Pro,A-31,S,S,O,1-Adm,H),(3-32,i-Pro,A-32,S,S,O,1-Adm,H),(3-33,i-Pro,A-33,S,S,O,1-Adm,H),(3-34,i-Pro,A-34,S,S,O,1-Adm,H),(3-35,i-Pro,A-35,S,S,O,1-Adm,H),(3-36,i-Pro,A-36,S,S,O,1-Adm,H),(3-37,i-Pro,A-1,S,S,O,2-Adm,H),(3-38,i-Pro,A-2,S,S,O,2-Adm,H),(3-39,i-Pro,A-3,S,S,O,2-Adm,H),(3-40,i-Pro,A-4,S,S,O,2-Adm,H),(3-41,i-Pro,A-5,S,S,O,2-Adm,H),(3-42,i-Pro,A-6,S,S,O,2-Adm,H),(3-43,i-Pro,A-7,S,S,O,2-Adm,H),(3-44,i-Pro,A-8,S,S,O,2-Adm,H),(3-45,i-Pro,A-9,S,S,O,2-Adm,H),(3-46,i-Pro,A-110,S,S,O,2-Adm,H),(3-47,i-Pro,A-111,S,S,O,2-Adm,H),(3-48,i-Pro,A-12,S,S,O,2-Adm,H),(3-49,i-Pro,A-13,S,S,O,2-Adm,H),(3-50,i-Pro,A-14,S,S,O,2-Adm,H),(3-51,i-Pro,A-15,S,S,O,2-Adm,H),(3-52,i-Pro,A-16,S,S,O,2-Adm,H),(3-53,i-Pro,A-17,S,S,O,2-Adm,H),(3-54,i-Pro,A-18,S,S,O,2-Adm,H),(3-55,i-Pro,A-119,S,S,O,2-Adm,H),(3-56,i-Pro,A-20,S,S,O,2-Adm,H),(3-57,i-Pro,A-21,S,S,O,2-Adm,H),(3-58,i-Pro,A-22,S,S,O,2-Adm,H),(3-59,i-Pro,A-23,S,S,O,2-Adm,H),(3-60,i-Pro,A-24,S,S,O,2-Adm,H),(3-61,i-Pro,A-25,S,S,O,2-Adm,H),(3-62,i-Pro,A-26,S,S,O,2-Adm,H),(3-63,i-Pro,A-27,S,S,O,2-Adm,H),(3-64,i-Pro,A-28,S,S,O,2-Adm,H),(3-65,i-Pro,A-29,S,S,O,2-Adm,H),(3-66,i-Pro,A-30,S,S,O,2-Adm,H),(3-67,i-Pro,A-31,S,S,O,2-Adm,H),(3-68,i-Pro,A-32,S,S,O,2-Adm,H),(3-69,i-Pro,A-33,S,S,O,2-Adm,H),(3-70,i-Pro,A-34,S,S,O,2-Adm,H),(3-71,i-Pro,A-35,S,S,O,2-Adm,H),(3-72,i-Pro,A-36,S,S,O,2-Adm,H),(3-73,i-Pro,A-1,S,S,O,5-OH-2-Adm,H),(3-74,i-Pro,A-2,S,S,O,5-OH-2-Adm,H),(3-75,i-Pro,A-3,S,S,O,5-OH-2-Adm,H),(3-76,i-Pro,A-4,S,S,O,5-OH-2-Adm,H),(3-77,i-Pro,A-5,S,S,O,5-OH-2-Adm,H),(3-78,i-Pro,A-6,S,S,O,5-OH-2-Adm,H),(3-79,i-Pro,A-7,S,S,O,5-OH-2-Adm,H),(3-80,i-Pro,A-8,S,S,O,5-OH-2-Adm,H),(3-81,i-Pro,A-9,S,S,O,5-OH-2-Adm,H),(3-82,i-Pro,A-11,S,S,O,5-OH-2-Adm,H),(3-83,i-Pro,A-11,S,S,O,5-OH-2-Adm,H),(3-84,i-Pro,A-12,S,S,O,5-OH-2-Adm,H),(3-85,i-Pro,A-13,S,S,O,5-OH-2-Adm,H),(3-86,i-Pro,A-14,S,S,O,5-OH-2-Adm,H),(3-87,i-Pro,A-15,S,S,O,5-OH-2-Adm,H),(3-88,i-Pro,A-16,S,S,O,5-OH-2-Adm,H),(3-89,i-Pro,A-17,S,S,O,5-OH-2-Adm,H),(3-90,i-Pro,A-18,S,S,O,5-OH-2-Adm,H),(3-91,i-Pro,A-19,S,S,O,5-OH-2-Adm,H),(3-92,i-Pro,A-20,S,S,O,5-OH-2-Adm,H),(3-93,i-Pro,A-21,S,S,O,5-OH-2-Adm,H),(3-94,i-Pro,A-22,S,S,O,5-OH-2-Adm,H),(3-95,i-Pro,A-23,S,S,O,5-OH-2-Adm,H),(3-96,i-Pro,A-24,S,S,O,5-OH-2-Adm,H),(3-97,i-Pro,A-25,S,S,O,5-OH-2-Adm,H),(3-98,i-Pro,A-26,S,S,O,5-OH-2-Adm,H),(3-99,i-Pro,A-27,S,S,O,5-OH-2-Adm,H),(3-110,i-Pro,A-28,S,S,O,5-OH-2-Adm,H),(3-101,i-Pro,A-29,S,S,O,5-OH-2-Adm,H),(3-102,i-Pro,A-30,S,S,O,5-OH-2-Adm,H),(3-103,i-Pro,A-31,S,S,O,5-OH-2-Adm,H),(3-104,i-Pro,A-32,S,S,O,5-OH-2-Adm,H),(3-105,i-Pro,A-33,S,S,O,5-OH-2-Adm,H),(3-106,i-Pro,A-34,S,S,O,5-OH-2-Adm,H),(3-107,i-Pro,A-35,S,S,O,5-OH-2-Adm,H),(3-108,i-Pro,A-36,S,S,O,5-OH-2-Adm,H),(3-119,i-Pro,B-1,S,S,O,1-Adm,H),(3-111,i-Pro,B-2,S,S,O,1-Adm,H),(3-11,i-Pro,B-3,S,S,O,1-Adm,H),(3-112,i-Pro,B-4,S,S,O,1-Adm,H),(3-113,i-Pro,B-5,S,S,O,1-Adm,H),(3-114,i-Pro,B-6,S,S,O,1-Adm,H),(3-115,i-Pro,B-7,S,S,O,1-Adm,H),(3-116,i-Pro,B-8,S,S,O,1-Adm,H),(3-117,i-Pro,B-9,S,S,O,1-Adm,H),(3-118,i-Pro,B-10,S,S,O,1-Adm,H),(3-119,i-Pro,B-11,S,S,O,1-Adm,H),(3-120,i-Pro,B-12,S,S,O,1-Adm,H),(3-121,i-Pro,B-13,S,S,O,1-Adm,H),(3-122,i-Pro,B-14,S,S,O,1-Adm,H),(3-123,i-Pro,B-15,S,S,O,1-Adm,H),(3-124,i-Pro,B-16,S,S,O,1-Adm,H),(3-125,i-Pro,B-17,S,S,O,1-Adm,H),(3-126,i-Pro,B-18,S,S,O,1-Adm,H),(3-127,i-Pro,B-119,S,S,O,1-Adm,H),(3-128,i-Pro,B-20,S,S,O,1-Adm,H),(3-129,i-Pro,B-21,S,S,O,1-Adm,H),(3-130,i-Pro,B-22,S,S,O,1-Adm,H),(3-131,i-Pro,B-23,S,S,O,1-Adm,H),(3-132,i-Pro,B-24,S,S,O,1-Adm,H),(3-133,i-Pro,B-25,S,S,O,1-Adm,H),(3-134,i-Pro,B-26,S,S,O,1-Adm,H),(3-135,i-Pro,B-27,S,S,O,1-Adm,H),(3-136,i-Pro,B-28,S,S,O,1-Adm,H),(3-137,i-Pro,B-29,S,S,O,1-Adm,H),(3-138,i-Pro,B-30,S,S,O,1-Adm,H),(3-139,i-Pro,B-31,S,S,O,1-Adm,H),(3-140,i-Pro,B-32,S,S,O,1-Adm,H),(3-141,i-Pro,B-33,S,S,O,1-Adm,H),(3-142,i-Pro,B-34,S,S,O,1-Adm,H),(3-143,i-Pro,B-35,S,S,O,11-Adm,H),(3-144,i-Pro,B-36,S,S,O,1-Adm,H),(3-145,i-Pro,B-1,S,S,O,2-Adm,H),(3-146,i-Pro,B-2,S,S,O,2-Adm,H),(3-147,i-Pro,B-3,S,S,O,2-Adm,H),(3-148,i-Pro,B-4,S,S,O,2-Adm,H),(3-149,i-Pro,B-5,S,S,O,2-Adm,H),(3-150,i-Pro,B-6,S,S,O,2-Adm,H),(3-151,i-Pro,B-7,S,S,O,2-Adm,H),(3-152,i-Pro,B-8,S,S,O,2-Adm,H),(3-153,i-Pro,B-9,S,S,O,2-Adm,H),(3-154,i-Pro,B-110,S,S,O,2-Adm,H),(3-155,i-Pro,B-111,S,S,O,2-Adm,H),(3-156,i-Pro,B-12,S,S,O,2-Adm,H),(3-157,i-Pro,B-13,S,S,O,2-Adm,H),(3-158,i-Pro,B-14,S,S,O,2-Adm,H),(3-159,i-Pro,B-15,S,S,O,2-Adm,H),(3-160,i-Pro,B-16,S,S,O,2-Adm,H),(3-161,i-Pro,B-17,S,S,O,2-Adm,H),(3-162,i-Pro,B-18,S,S,O,2-Adm,H),(3-163,i-Pro,B-119,S,S,O,2-Adm,H),(3-164,i-Pro,B-20,S,S,O,2-Adm,H),(3-165,i-Pro,B-21,S,S,O,2-Adm,H),(3-166,i-Pro,B-22,S,S,O,2-Adm,H),(3-167,i-Pro,B-23,S,S,O,2-Adm,H),(3-168,i-Pro,B-24,S,S,O,2-Adm,H),(3-169,i-Pro,B-25,S,S,O,2-Adm,H),(3-170,i-Pro,B-26,S,S,O,2-Adm,H),(3-171,i-Pro,B-27,S,S,O,2-Adm,H),(3-172,i-Pro,B-28,S,S,O,2-Adm,H),(3-173,i-Pro,B-29,S,S,O,2-Adm,H),(3-174,i-Pro,B-30,S,S,O,2-Adm,H),(3-175,i-Pro,B-31,S,S,O,2-Adm,H),(3-176,i-Pro,B-32,S,S,O,2-Adm,H),(3-177,i-Pro,B-33,S,S,O,2-Adm,H),(3-178,i-Pro,B-34,S,S,O,2-Adm,H),(3-179,i-Pro,B-35,S,S,O,2-Adm,H),(3-180,i-Pro,B-36,S,S,O,2-Adm,H),(3-181,i-Pro,B-1,S,S,O,5-OH-2-Adm,H),(3-182,i-Pro,B-2,S,S,O,5-OH-2-Adm,H),(3-183,i-Pro,B-3,S,S,O,5-OH-2-Adm,H),(3-184,i-Pro,B-4,S,S,O,5-OH-2-Adm,H),(3-185,i-Pro,B-5,S,S,O,5-OH-2-Adm,H),(3-186,i-Pro,B-6,S,S,O,5-OH-2-Adm,H),(3-187,i-Pro,B-7,S,S,O,5-OH-2-Adm,H),(3-188,i-Pro,B-8,S,S,O,5-OH-2-Adm,H),(3-189,i-Pro,B-9,S,S,O,5-OH-2-Adm,H),(3-190,i-Pro,B-10,S,S,O,5-OH-2-Adm,H),(3-191,i-Pro,B-11,S,S,O,5-OH-2-Adm,H),(3-192,i-Pro,B-12,S,S,O,5-OH-2-Adm,H),(3-193,i-Pro,B-13,S,S,O,5-OH-2-Adm,H),(3-194,i-Pro,B-14,S,S,O,5-OH-2-Adm,H),(3-195,i-Pro,B-15,S,S,O,5-OH-2-Adm,H),(3-196,i-Pro,B-16,S,S,O,5-OH-2-Adm,H),(3-197,i-Pro,B-17,S,S,O,5-OH-2-Adm,H),(3-198,i-Pro,B-18,S,S,O,5-OH-2-Adm,H),(3-199,i-Pro,B-19,S,S,O,5-OH-2-Adm,H),(3-200,i-Pro,B-20,S,S,O,5-OH-2-Adm,H),(3-201,i-Pro,B-21,S,S,O,5-OH-2-Adm,H),(3-202,i-Pro,B-22,S,S,O,5-OH-2-Adm,H),(3-203,i-Pro,B-23,S,S,O,5-OH-2-Adm,H),(3-204,i-Pro,B-24,S,S,O,5-OH-2-Adm,H),(3-205,i-Pro,B-25,S,S,O,5-OH-2-Adm,H),(3-206,i-Pro,B-26,S,S,O,5-OH-2-Adm,H),(3-207,i-Pro,B-27,S,S,O,5-OH-2-Adm,H),(3-208,i-Pro,B-28,S,S,O,5-OH-2-Adm,H),(3-209,i-Pro,B-29,S,S,O,5-OH-2-Adm,H),(3-210,i-Pro,B-30,S,S,O,5-OH-2-Adm,H),(3-211,i-Pro,B-31,S,S,O,5-OH-2-Adm,H),(3-212,i-Pro,B-32,S,S,O,5-OH-2-Adm,H),(3-213,i-Pro,B-33,S,S,O,5-OH-2-Adm,H),(3-214,i-Pro,B-34,S,S,O,5-OH-2-Adm,H),(3-215,i-Pro,B-35,S,S,O,5-OH-2-Adm,H),(3-216,i-Pro,B-36,S,S,O,5-OH-2-Adm,H),(3-217,i-Pro,C-1,S,S,O,1-Adm,H),(3-218,i-Pro,C-2,S,S,O,1-Adm,H),(3-219,i-Pro,C-3,S,S,O,1-Adm,H),(3-220,i-Pro,C-4,S,S,O,1-Adm,H),(3-221,i-Pro,C-5,S,S,O,1-Adm,H),(3-222,i-Pro,C-6,S,S,O,1-Adm,H),(3-223,i-Pro,C-7,S,S,O,1-Adm,H),(3-224,i-Pro,C-8,S,S,O,1-Adm,H),(3-225,i-Pro,C-9,S,S,O,1-Adm,H),(3-226,i-Pro,C-11,S,S,O,1-Adm,H),(3-227,i-Pro,C-11,S,S,O,1-Adm,H),(3-228,i-Pro,C-12,S,S,O,1-Adm,H),(3-229,i-Pro,C-13,S,S,O,1-Adm,H),(3-230,i-Pro,C-14,S,S,O,1-Adm,H),(3-231,i-Pro,C-15,S,S,O,1-Adm,H),(3-232,i-Pro,C-16,S,S,O,1-Adm,H),(3-233,i-Pro,C-17,S,S,O,1-Adm,H),(3-234,i-Pro,C-18,S,S,O,1-Adm,H),(3-235,i-Pro,C-19,S,S,O,1-Adm,H),(3-236,i-Pro,C-20,S,S,O,1-Adm,H),(3-237,i-Pro,C-21,S,S,O,1-Adm,H),(3-238,i-Pro,C-22,S,S,O,1-Adm,H),(3-239,i-Pro,C-23,S,S,O,1-Adm,H),(3-240,i-Pro,C-24,S,S,O,1-Adm,H),(3-241,i-Pro,C-2,S,S,O,1-Adm,H),(3-242,i-Pro,C-26,S,S,O,1-Adm,H),(3-243,i-Pro,C-27,S,S,O,1-Adm,H),(3-244,i-Pro,C-28,S,S,O,1-Adm,H),(3-245,i-Pro,C-29,S,S,O,1-Adm,H),(3-246,i-Pro,C-30,S,S,O,1-Adm,H),(3-247,i-Pro,C-31,S,S,O,1-Adm,H),(3-248,i-Pro,C-32,S,S,O,1-Adm,H),(3-249,i-Pro,C-33,S,S,O,1-Adm,H),(3-250,i-Pro,C-34,S,S,O,1-Adm,H),(3-251,i-Pro,C-35,S,S,O,1-Adm,H),(3-252,i-Pro,C-36,S,S,O,1-Adm,H),(3-253,i-Pro,C-1,S,S,O,2-Adm,H),(3-254,i-Pro,C-2,S,S,O,2-Adm,H),(3-255,i-Pro,C-3,S,S,O,2-Adm,H),(3-256,i-Pro,C-4,S,S,O,2-Adm,H),(3-257,i-Pro,C-5,S,S,O,2-Adm,H),(3-258,i-Pro,C-6,S,S,O,2-Adm,H),(3-259,i-Pro,C-7,S,S,O,2-Adm,H),(3-260,i-Pro,C-8,S,S,O,2-Adm,H),(3-261,i-Pro,C-9,S,S,O,2-Adm,H),(3-262,i-Pro,C-11,S,S,O,2-Adm,H),(3-263,i-Pro,C-11,S,S,O,2-Adm,H),(3-264,i-Pro,C-12,S,S,O,2-Adm,H),(3-265,i-Pro,C-13,S,S,O,2-Adm,H),(3-266,i-Pro,C-14,S,S,O,2-Adm,H),(3-267,i-Pro,C-15,S,S,O,2-Adm,H),(3-268,i-Pro,C-16,S,S,O,2-Adm,H),(3-269,i-Pro,C-17,S,S,O,2-Adm,H),(3-270,i-Pro,C-18,S,S,O,2-Adm,H),(3-271,i-Pro,C-19,S,S,O,2-Adm,H),(3-272,i-Pro,C-20,S,S,O,2-Adm,H),(3-273,i-Pro,C-21,S,S,O,2-Adm,H),(3-274,i-Pro,C-22,S,S,O,2-Adm,H),(3-275,i-Pro,C-23,S,S,O,2-Adm,H),(3-276,i-Pro,C-24,S,S,O,2-Adm,H),(3-277,i-Pro,C-25,S,S,O,2-Adm,H),(3-278,i-Pro,C-26,S,S,O,2-Adm,H),(3-279,i-Pro,C-27,S,S,O,2-Adm,H),(3-280,i-Pro,C-28,S,S,O,2-Adm,H),(3-281,i-Pro,C-29,S,S,O,2-Adm,H),(3-282,i-Pro,C-30,S,S,O,2-Adm,H),(3-283,i-Pro,C-31,S,S,O,2-Adm,H),(3-284,i-Pro,C-32,S,S,O,2-Adm,H),(3-285,i-Pro,C-33,S,S,O,2-Adm,H),(3-286,i-Pro,C-34,S,S,O,2-Adm,H),(3-287,i-Pro,C-35,S,S,O,2-Adm,H),(3-288,i-Pro,C-36,S,S,O,2-Adm,H),(3-289,i-Pro,C-1,S,S,O,5-OH-2-Adm,H),(3-290,i-Pro,C-2,S,S,O,5-OH-2-Adm,H),(3-291,i-Pro,C-3,S,S,O,5-OH-2-Adm,H),(3-292,i-Pro,C-4,S,S,O,5-OH-2-Adm,H),(3-293,i-Pro,C-5,S,S,O,5-OH-2-Adm,H),(3-294,i-Pro,C-6,S,S,O,5-OH-2-Adm,H),(3-295,i-Pro,C-7,S,S,O,5-OH-2-Adm,H),(3-296,i-Pro,C-8,S,S,O,5-OH-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S,S,O,1-Adm,H),(3-732,i-Pro,J-3,S,S,O,1-Adm,H),(3-733,i-Pro,J-4,S,S,O,1-Adm,H),(3-734,i-Pro,J-5,S,S,O,1-Adm,H),(3-735,i-Pro,J-6,S,S,O,1-Adm,H),(3-736,i-Pro,J-7,S,S,O,1-Adm,H),(3-737,i-Pro,J-8,S,S,O,1-Adm,H),(3-738,i-Pro,J-9,S,S,O,1-Adm,H),(3-739,i-Pro,J-1,S,S,O,2-Adm,H),(3-740,i-Pro,J-2,S,S,O,2-Adm,H),(3-741,i-Pro,J-3,S,S,O,2-Adm,H),(3-742,i-Pro,J-4,S,S,O,2-Adm,H),(3-743,i-Pro,J-5,S,S,O,2-Adm,H),(3-744,i-Pro,J-6,S,S,O,2-Adm,H),(3-745,i-Pro,J-7,S,S,O,2-Adm,H),(3-746,i-Pro,J-8,S,S,O,2-Adm,H),(3-747,i-Pro,J-9,S,S,O,2-Adm,H),(3-748,i-Pro,J-1,S,S,O,5-OH-2-Adm,H),(3-749,i-Pro,J-2,S,S,O,5-OH-2-Adm,H),(3-750,i-Pro,J-3,S,S,O,5-OH-2-Adm,H),(3-751,i-Pro,J-4,S,S,O,5-OH-2-Adm,H),(3-752,i-Pro,J-5,S,S,O,5-OH-2-Adm,H),(3-753,i-Pro,J-6,S,S,O,5-OH-2-Adm,H),(3-754,i-Pro,J-7,S,S,O,5-OH-2-Adm,H),(3-755,i-Pro,J-8,S,S,O,5-OH-2-Adm,H),(3-756,i-Pro,J-9,S,S,O,5-OH-2-Adm,H),(3-757,i-Pro,K-1,S,S,O,1-Adm,H),(3-758,i-Pro,K-2,S,S,O,1-Adm,H),(3-759,i-Pro,K-3,S,S,O,1-Adm,H),(3-760,i-Pro,K-4,S,S,O,1-Adm,H),(3-761,i-Pro,K-5,S,S,O,1-Adm,H),(3-762,i-Pro,K-6,S,S,O,1-Adm,H),(3-763,i-Pro,K-7,S,S,O,1-Adm,H),(3-764,i-Pro,K-8,S,S,O,1-Adm,H),(3-765,i-Pro,K-9,S,S,O,1-Adm,H),(3-766,i-Pro,K-1,S,S,O,2-Adm,H),(3-767,i-Pro,K-2,S,S,O,2-Adm,H),(3-768,i-Pro,K-3,S,S,O,2-Adm,H),(3-769,i-Pro,K-4,S,S,O,2-Adm,H),(3-770,i-Pro,K-5,S,S,O,2-Adm,H),(3-771,i-Pro,K-6,S,S,O,2-Adm,H),(3-772,i-Pro,K-7,S,S,O,2-Adm,H),(3-773,i-Pro,K-8,S,S,O,2-Adm,H),(3-774,i-Pro,K-9,S,S,O,2-Adm,H),(3-775,i-Pro,K-1,S,S,O,5-OH-2-Adm,H),(3-776,i-Pro,K-2,S,S,O,5-OH-2-Adm,H),(3-777,i-Pro,K-3,S,S,O,5-OH-2-Adm,H),(3-778,i-Pro,K-4,S,S,O,5-OH-2-Adm,H),(3-779,i-Pro,K-5,S,S,O,5-OH-2-Adm,H),(3-780,i-Pro,K-6,S,S,O,5-OH-2-Adm,H),(3-781,i-Pro,K-7,S,S,O,5-OH-2-Adm,H),(3-782,i-Pro,K-8,S,S,O,5-OH-2-Adm,H),(3-783,i-Pro,K-9,S,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(4-1,i-Bu,A-1,O,S,O,1-Adm,H),(4-2,i-Bu,A-2,O,S,O,1-Adm,H),(4-3,i-Bu,A-3,O,S,O,1-Adm,H),(4-4,i-Bu,A-4,O,S,O,1-Adm,H),(4-5,i-Bu,A-5,O,S,O,1-Adm,H),(4-6,i-Bu,A-6,O,S,O,1-Adm,H),(4-7,i-Bu,A-7,O,S,O,1-Adm,H),(4-8,i-Bu,A-8,O,S,O,1-Adm,H),(4-9,i-Bu,A-9,O,S,O,1-Adm,H),(4-10,i-Bu,A-10,O,S,O,1-Adm,H),(4-11,i-Bu,A-11,O,S,O,1-Adm,H),(4-12,i-Bu,A-12,O,S,O,1-Adm,H),(4-13,i-Bu,A-13,O,S,O,1-Adm,H),(4-14,i-Bu,A-14,O,S,O,1-Adm,H),(4-15,i-Bu,A-15,O,S,O,1-Adm,H),(4-16,i-Bu,A-16,O,S,O,1-Adm,H),(4-17,i-Bu,A-17,O,S,O,1-Adm,H),(4-18,i-Bu,A-18,O,S,O,1-Adm,H),(4-19,i-Bu,A-19,O,S,O,1-Adm,H),(4-20,i-Bu,A-20,O,S,O,1-Adm,H),(4-21,i-Bu,A-21,O,S,O,1-Adm,H),(4-22,i-Bu,A-22,O,S,O,1-Adm,H),(4-23,i-Bu,A-23,O,S,O,1-Adm,H),(4-24,i-Bu,A-24,O,S,O,1-Adm,H),(4-25,i-Bu,A-25,O,S,O,1-Adm,H),(4-26,i-Bu,A-26,O,S,O,1-Adm,H),(4-27,i-Bu,A-27,O,S,O,1-Adm,H),(4-28,i-Bu,A-28,O,S,O,1-Adm,H),(4-29,i-Bu,A-29,O,S,O,1-Adm,H),(4-30,i-Bu,A-30,O,S,O,1-Adm,H),(4-31,i-Bu,A-31,O,S,O,1-Adm,H),(4-32,i-Bu,A-32,O,S,O,1-Adm,H),(4-33,i-Bu,A-33,O,S,O,1-Adm,H),(4-34,i-Bu,A-34,O,S,O,1-Adm,H),(4-35,i-Bu,A-35,O,S,O,1-Adm,H),(4-36,i-Bu,A-36,O,S,O,1-Adm,H),(4-37,i-Bu,A-1,O,S,O,2-Adm,H),(4-38,i-Bu,A-2,O,S,O,2-Adm,H),(4-39,i-Bu,A-3,O,S,O,2-Adm,H),(4-40,i-Bu,A-4,O,S,O,2-Adm,H),(4-41,i-Bu,A-5,O,S,O,2-Adm,H),(4-42,i-Bu,A-6,O,S,O,2-Adm,H),(4-43,i-Bu,A-7,O,S,O,2-Adm,H),(4-44,i-Bu,A-8,O,S,O,2-Adm,H),(4-45,i-Bu,A-9,O,S,O,2-Adm,H),(4-46,i-Bu,A-10,O,S,O,2-Adm,H),(4-47,i-Bu,A-11,O,S,O,2-Adm,H),(4-48,i-Bu,A-12,O,S,O,2-Adm,H),(4-49,i-Bu,A-13,O,S,O,2-Adm,H),(4-50,i-Bu,A-14,O,S,O,2-Adm,H),(4-51,i-Bu,A-15,O,S,O,2-Adm,H),(4-52,i-Bu,A-16,O,S,O,2-Adm,H),(4-53,i-Bu,A-17,O,S,O,2-Adm,H),(4-54,i-Bu,A-18,O,S,O,2-Adm,H),(4-55,i-Bu,A-19,O,S,O,2-Adm,H),(4-56,i-Bu,A-20,O,S,O,2-Adm,H),(4-57,i-Bu,A-21,O,S,O,2-Adm,H),(4-58,i-Bu,A-22,O,S,O,2-Adm,H),(4-59,i-Bu,A-23,O,S,O,2-Adm,H),(4-60,i-Bu,A-24,O,S,O,2-Adm,H),(4-61,i-Bu,A-25,O,S,O,2-Adm,H),(4-62,i-Bu,A-26,O,S,O,2-Adm,H),(4-63,i-Bu,A-27,O,S,O,2-Adm,H),(4-64,i-Bu,A-28,O,S,O,2-Adm,H),(4-65,i-Bu,A-29,O,S,O,2-Adm,H),(4-66,i-Bu,A-30,O,S,O,2-Adm,H),(4-67,i-Bu,A-31,O,S,O,2-Adm,H),(4-68,i-Bu,A-32,O,S,O,2-Adm,H),(4-69,i-Bu,A-33,O,S,O,2-Adm,H),(4-70,i-Bu,A-34,O,S,O,2-Adm,H),(4-71,i-Bu,A-35,O,S,O,2-Adm,H),(4-72,i-Bu,A-36,O,S,O,2-Adm,H),(4-73,i-Bu,A-1,O,S,O,5-OH-2-Adm,H),(4-74,i-Bu,A-2,O,S,O,5-OH-2-Adm,H),(4-75,i-Bu,A-3,O,S,O,5-OH-2-Adm,H),(4-76,i-Bu,A-4,O,S,O,5-OH-2-Adm,H),(4-77,i-Bu,A-5,O,S,O,5-OH-2-Adm,H),(4-78,i-Bu,A-6,O,S,O,5-OH-2-Adm,H),(4-79,i-Bu,A-7,O,S,O,5-OH-2-Adm,H),(4-80,i-Bu,A-8,O,S,O,5-OH-2-Adm,H),(4-81,i-Bu,A-9,O,S,O,5-OH-2-Adm,H),(4-82,i-Bu,A-10,O,S,O,5-OH-2-Adm,H),(4-83,i-Bu,A-11,O,S,O,5-OH-2-Adm,H),(4-84,i-Bu,A-12,O,S,O,5-OH-2-Adm,H),(4-85,i-Bu,A-13,O,S,O,5-OH-2-Adm,H),(4-86,i-Bu,A-14,O,S,O,5-OH-2-Adm,H),(4-87,i-Bu,A-15,O,S,O,5-OH-2-Adm,H),(4-88,i-Bu,A-16,O,S,O,5-OH-2-Adm,H),(4-89,i-Bu,A-17,O,S,O,5-OH-2-Adm,H),(4-90,i-Bu,A-18,O,S,O,5-OH-2-Adm,H),(4-91,i-Bu,A-19,O,S,O,5-OH-2-Adm,H),(4-92,i-Bu,A-20,O,S,O,5-OH-2-Adm,H),(4-93,i-Bu,A-21,O,S,O,5-OH-2-Adm,H),(4-94,i-Bu,A-22,O,S,O,5-OH-2-Adm,H),(4-95,i-Bu,A-23,O,S,O,5-OH-2-Adm,H),(4-96,i-Bu,A-24,O,S,O,5-OH-2-Adm,H),(4-97,i-Bu,A-25,O,S,O,5-OH-2-Adm,H),(4-98,i-Bu,A-26,O,S,O,5-OH-2-Adm,H),(4-99,i-Bu,A-27,O,S,O,5-OH-2-Adm,H),(4-100,i-Bu,A-28,O,S,O,5-OH-2-Adm,H),(4-101,i-Bu,A-29,O,S,O,5-OH-2-Adm,H),(4-102,i-Bu,A-30,O,S,O,5-OH-2-Adm,H),(4-103,i-Bu,A-31,O,S,O,5-OH-2-Adm,H),(4-104,i-Bu,A-32,O,S,O,5-OH-2-Adm,H),(4-105,i-Bu,A-33,O,S,O,5-OH-2-Adm,H),(4-106,i-Bu,A-34,O,S,O,5-OH-2-Adm,H),(4-107,i-Bu,A-35,O,S,O,5-OH-2-Adm,H),(4-108,i-Bu,A-36,O,S,O,5-OH-2-Adm,H),(4-109,i-Bu,B-1,O,S,O,1-Adm,H),(4-110,i-Bu,B-2,O,S,O,1-Adm,H),(4-111,i-Bu,B-3,O,S,O,1-Adm,H),(4-112,i-Bu,B-4,O,S,O,1-Adm,H),(4-113,i-Bu,B-5,O,S,O,1-Adm,H),(4-114,i-Bu,B-6,O,S,O,1-Adm,H),(4-115,i-Bu,B-7,O,S,O,1-Adm,H),(4-116,i-Bu,B-8,O,S,O,1-Adm,H),(4-117,i-Bu,B-9,O,S,O,1-Adm,H),(4-118,i-Bu,B-10,O,S,O,1-Adm,H),(4-119,i-Bu,B-1,O,S,O,1-Adm,H),(4-120,i-Bu,B-12,O,S,O,1-Adm,H),(4-121,i-Bu,B-13,O,S,O,1-Adm,H),(4-122,i-Bu,B-14,O,S,O,1-Adm,H),(4-123,i-Bu,B-15,O,S,O,1-Adm,H),(4-124,i-Bu,B-16,O,S,O,1-Adm,H),(4-125,i-Bu,B-17,O,S,O,1-Adm,H),(4-126,i-Bu,B-18,O,S,O,1-Adm,H),(4-127,i-Bu,B-19,O,S,O,1-Adm,H),(4-128,i-Bu,B-20,O,S,O,1-Adm,H),(4-129,i-Bu,B-21,O,S,O,1-Adm,H),(4-130,i-Bu,B-22,O,S,O,1-Adm,H),(4-131,i-Bu,B-23,O,S,O,1-Adm,H),(4-132,i-Bu,B-24,O,S,O,1-Adm,H),(4-133,i-Bu,B-25,O,S,O,1-Adm,H),(4-134,i-Bu,B-26,O,S,O,1-Adm,H),(4-135,i-Bu,B-27,O,S,O,1-Adm,H),(4-136,i-Bu,B-28,O,S,O,1-Adm,H),(4-137,i-Bu,B-29,O,S,O,1-Adm,H),(4-138,i-Bu,B-30,O,S,O,1-Adm,H),(4-139,i-Bu,B-31,O,S,O,1-Adm,H),(4-140,i-Bu,B-32,O,S,O,1-Adm,H),(4-141,i-Bu,B-33,O,S,O,1-Adm,H),(4-142,i-Bu,B-34,O,S,O,1-Adm,H),(4-143,i-Bu,B-35,O,S,O,1-Adm,H),(4-144,i-Bu,B-36,O,S,O,1-Adm,H),(4-145,i-Bu,B-1,O,S,O,2-Adm,H),(4-146,i-Bu,B-2,O,S,O,2-Adm,H),(4-147,i-Bu,B-3,O,S,O,2-Adm,H),(4-148,i-Bu,B-4,O,S,O,2-Adm,H),(4-149,i-Bu,B-5,O,S,O,2-Adm,H),(4-150,i-Bu,B-6,O,S,O,2-Adm,H),(4-151,i-Bu,B-7,O,S,O,2-Adm,H),(4-152,i-Bu,B-8,O,S,O,2-Adm,H),(4-153,i-Bu,B-9,O,S,O,2-Adm,H),(4-154,i-Bu,B-10,O,S,O,2-Adm,H),(4-155,i-Bu,B-11,O,S,O,2-Adm,H),(4-156,i-Bu,B-12,O,S,O,2-Adm,H),(4-157,i-Bu,B-13,O,S,O,2-Adm,H),(4-158,i-Bu,B-14,O,S,O,2-Adm,H),(4-159,i-Bu,B-15,O,S,O,2-Adm,H),(4-160,i-Bu,B-16,O,S,O,2-Adm,H),(4-161,i-Bu,B-17,O,S,O,2-Adm,H),(4-162,i-Bu,B-18,O,S,O,2-Adm,H),(4-163,i-Bu,B-19,O,S,O,2-Adm,H),(4-164,i-Bu,B-20,O,S,O,2-Adm,H),(4-165,i-Bu,B-21,O,S,O,2-Adm,H),(4-166,i-Bu,B-22,O,S,O,2-Adm,H),(4-167,i-Bu,B-23,O,S,O,2-Adm,H),(4-168,i-Bu,B-24,O,S,O,2-Adm,H),(4-169,i-Bu,B-25,O,S,O,2-Adm,H),(4-170,i-Bu,B-26,O,S,O,2-Adm,H),(4-171,i-Bu,B-27,O,S,O,2-Adm,H),(4-172,i-Bu,B-28,O,S,O,2-Adm,H),(4-173,i-Bu,B-29,O,S,O,2-Adm,H),(4-174,i-Bu,B-30,O,S,O,2-Adm,H),(4-175,i-Bu,B-31,O,S,O,2-Adm,H),(4-176,i-Bu,B-32,O,S,O,2-Adm,H),(4-177,i-Bu,B-33,O,S,O,2-Adm,H),(4-178,i-Bu,B-34,O,S,O,2-Adm,H),(4-179,i-Bu,B-35,O,S,O,2-Adm,H),(4-180,i-Bu,B-36,O,S,O,2-Adm,H),(4-181,i-Bu,B-1,O,S,O,5-OH-2-Adm,H),(4-182,i-Bu,B-2,O,S,O,5-OH-2-Adm,H),(4-183,i-Bu,B-3,O,S,O,5-OH-2-Adm,H),(4-184,i-Bu,B-4,O,S,O,5-OH-2-Adm,H),(4-185,i-Bu,B-5,O,S,O,5-OH-2-Adm,H),(4-186,i-Bu,B-6,O,S,O,5-OH-2-Adm,H),(4-187,i-Bu,B-7,O,S,O,5-OH-2-Adm,H),(4-188,i-Bu,B-8,O,S,O,5-OH-2-Adm,H),(4-189,i-Bu,B-9,O,S,O,5-OH-2-Adm,H),(4-190,i-Bu,B-10,O,S,O,5-OH-2-Adm,H),(4-191,i-Bu,B-11,O,S,O,5-OH-2-Adm,H),(4-192,i-Bu,B-12,O,S,O,5-OH-2-Adm,H),(4-193,i-Bu,B-13,O,S,O,5-OH-2-Adm,H),(4-194,i-Bu,B-14,O,S,O,5-OH-2-Adm,H),(4-195,i-Bu,B-15,O,S,O,5-OH-2-Adm,H),(4-196,i-Bu,B-16,O,S,O,5-OH-2-Adm,H),(4-197,i-Bu,B-17,O,S,O,5-OH-2-Adm,H),(4-198,i-Bu,B-18,O,S,O,5-OH-2-Adm,H),(4-199,i-Bu,B-19,O,S,O,5-OH-2-Adm,H),(4-200,i-Bu,B-20,O,S,O,5-OH-2-Adm,H),(4-201,i-Bu,B-21,O,S,O,5-OH-2-Adm,H),(4-202,i-Bu,B-22,O,S,O,5-OH-2-Adm,H),(4-203,i-Bu,B-23,O,S,O,5-OH-2-Adm,H),(4-204,i-Bu,B-24,O,S,O,5-OH-2-Adm,H),(4-205,i-Bu,B-25,O,S,O,5-OH-2-Adm,H),(4-206,i-Bu,B-26,O,S,O,5-OH-2-Adm,H),(4-207,i-Bu,B-27,O,S,O,5-OH-2-Adm,H),(4-208,i-Bu,B-28,O,S,O,5-OH-2-Adm,H),(4-209,i-Bu,B-29,O,S,O,5-OH-2-Adm,H),(4-210,i-Bu,B-30,O,S,O,5-OH-2-Adm,H),(4-211,i-Bu,B-31,O,S,O,5-OH-2-Adm,H),(4-212,i-Bu,B-32,O,S,O,5-OH-2-Adm,H),(4-213,i-Bu,B-33,O,S,O,5-OH-2-Adm,H),(4-214,i-Bu,B-34,O,S,O,5-OH-2-Adm,H),(4-215,i-Bu,B-35,O,S,O,5-OH-2-Adm,H),(4-216,i-Bu,B-36,O,S,O,5-OH-2-Adm,H),(4-217,i-Bu,C-1,O,S,O,1-Adm,H),(4-218,i-Bu,C-2,O,S,O,1-Adm,H),(4-219,i-Bu,C-3,O,S,O,1-Adm,H),(4-220,i-Bu,C-4,O,S,O,1-Adm,H),(4-221,i-Bu,C-5,O,S,O,1-Adm,H),(4-222,i-Bu,C-6,O,S,O,1-Adm,H),(4-223,i-Bu,C-7,O,S,O,1-Adm,H),(4-224,i-Bu,C-8,O,S,O,1-Adm,H),(4-225,i-Bu,C-9,O,S,O,1-Adm,H),(4-226,i-Bu,C-10,O,S,O,1-Adm,H),(4-227,i-Bu,C-11,O,S,O,1-Adm,H),(4-228,i-Bu,C-12,O,S,O,1-Adm,H),(4-229,i-Bu,C-13,O,S,O,1-Adm,H),(4-230,i-Bu,C-14,O,S,O,1-Adm,H),(4-231,i-Bu,C-15,O,S,O,1-Adm,H),(4-232,i-Bu,C-16,O,S,O,1-Adm,H),(4-233,i-Bu,C-17,O,S,O,1-Adm,H),(4-234,i-Bu,C-18,O,S,O,1-Adm,H),(4-235,i-Bu,C-19,O,S,O,1-Adm,H),(4-236,i-Bu,C-20,O,S,O,1-Adm,H),(4-237,i-Bu,C-21,O,S,O,1-Adm,H),(4-238,i-Bu,C-22,O,S,O,1-Adm,H),(4-239,i-Bu,C-23,O,S,O,1-Adm,H),(4-240,i-Bu,C-24,O,S,O,1-Adm,H),(4-241,i-Bu,C-25,O,S,O,1-Adm,H),(4-242,i-Bu,C-26,O,S,O,1-Adm,H),(4-243,i-Bu,C-27,O,S,O,1-Adm,H),(4-244,i-Bu,C-28,O,S,O,1-Adm,H),(4-245,i-Bu,C-29,O,S,O,1-Adm,H),(4-246,i-Bu,C-30,O,S,O,1-Adm,H),(4-247,i-Bu,C-31,O,S,O,1-Adm,H),(4-248,i-Bu,C-32,O,S,O,1-Adm,H),(4-249,i-Bu,C-33,O,S,O,1-Adm,H),(4-250,i-Bu,C-34,O,S,O,1-Adm,H),(4-251,i-Bu,C-35,O,S,O,1-Adm,H),(4-252,i-Bu,C-36,O,S,O,1-Adm,H),(4-253,i-Bu,C-1,O,S,O,2-Adm,H),(4-254,i-Bu,C-2,O,S,O,2-Adm,H),(4-255,i-Bu,C-3,O,S,O,2-Adm,H),(4-256,i-Bu,C-4,O,S,O,2-Adm,H),(4-257,i-Bu,C-5,O,S,O,2-Adm,H),(4-258,i-Bu,C-6,O,S,O,2-Adm,H),(4-259,i-Bu,C-7,O,S,O,2-Adm,H),(4-260,i-Bu,C-8,O,S,O,2-Adm,H),(4-261,i-Bu,C-9,O,S,O,2-Adm,H),(4-262,i-Bu,C-10,O,S,O,2-Adm,H),(4-263,i-Bu,C-11,O,S,O,2-Adm,H),(4-264,i-Bu,C-12,O,S,O,2-Adm,H),(4-265,i-Bu,C-13,O,S,O,2-Adm,H),(4-266,i-Bu,C-14,O,S,O,2-Adm,H),(4-267,i-Bu,C-15,O,S,O,2-Adm,H),(4-268,i-Bu,C-16,O,S,O,2-Adm,H),(4-269,i-Bu,C-17,O,S,O,2-Adm,H),(4-270,i-Bu,C-18,O,S,O,2-Adm,H),(4-271,i-Bu,C-19,O,S,O,2-Adm,H),(4-272,i-Bu,C-20,O,S,O,2-Adm,H),(4-273,i-Bu,C-21,O,S,O,2-Adm,H),(4-274,i-Bu,C-22,O,S,O,2-Adm,H),(4-275,i-Bu,C-23,O,S,O,2-Adm,H),(4-276,i-Bu,C-24,O,S,O,2-Adm,H),(4-277,i-Bu,C-25,O,S,O,2-Adm,H),(4-278,i-Bu,C-26,O,S,O,2-Adm,H),(4-279,i-Bu,C-27,O,S,O,2-Adm,H),(4-280,i-Bu,C-28,O,S,O,2-Adm,H),(4-281,i-Bu,C-29,O,S,O,2-Adm,H),(4-282,i-Bu,C-30,O,S,O,2-Adm,H),(4-283,i-Bu,C-31,O,S,O,2-Adm,H),(4-284,i-Bu,C-32,O,S,O,2-Adm,H),(4-285,i-Bu,C-33,O,S,O,2-Adm,H),(4-286,i-Bu,C-34,O,S,O,2-Adm,H),(4-287,i-Bu,C-35,O,S,O,2-Adm,H),(4-288,i-Bu,C-36,O,S,O,2-Adm,H),(4-289,i-Bu,C-1,O,S,O,5-OH-2-Adm,H),(4-290,i-Bu,C-2,O,S,O,5-OH-2-Adm,H),(4-291,i-Bu,C-3,O,S,O,5-OH-2-Adm,H),(4-292,i-Bu,C-4,O,S,O,5-OH-2-Adm,H),(4-293,i-Bu,C-5,O,S,O,5-OH-2-Adm,H),(4-294,i-Bu,C-6,O,S,O,5-OH-2-Adm,H),(4-295,i-Bu,C-7,O,S,O,5-OH-2-Adm,H),(4-296,i-Bu,C-8,O,S,O,5-OH-2-Adm,H),(4-297,i-Bu,C-9,O,S,O,5-OH-2-Adm,H),(4-298,i-Bu,C-10,O,S,O,5-OH-2-Adm,H),(4-299,i-Bu,C-11,O,S,O,5-OH-2-Adm,H),(4-300,i-Bu,C-12,O,S,O,5-OH-2-Adm,H),(4-301,i-Bu,C-13,O,S,O,5-OH-2-Adm,H),(4-302,i-Bu,C-14,O,S,O,5-OH-2-Adm,H),(4-303,i-Bu,C-15,O,S,O,5-OH-2-Adm,H),(4-304,i-Bu,C-16,O,S,O,5-OH-2-Adm,H)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,F-29,O,S,O,2-Adm,H),(4-606,i-Bu,F-30,O,S,O,2-Adm,H),(4-607,i-Bu,F-31,O,S,O,2-Adm,H),(4-608,i-Bu,F-32,O,S,O,2-Adm,H),(4-609,i-Bu,F-33,O,S,O,2-Adm,H),(4-610,i-Bu,F-34,O,S,O,2-Adm,H),(4-611,i-Bu,F-35,O,S,O,2-Adm,H),(4-612,i-Bu,F-36,O,S,O,2-Adm,H),(4-613,i-Bu,F-1,O,S,O,5-OH-2-Adm,H),(4-614,i-Bu,F-2,O,S,O,5-OH-2-Adm,H),(4-615,i-Bu,F-3,O,S,O,5-OH-2-Adm,H),(4-616,i-Bu,F-4,O,S,O,5-OH-2-Adm,H),(4-617,i-Bu,F-5,O,S,O,5-OH-2-Adm,H),(4-618,i-Bu,F-6,O,S,O,5-OH-2-Adm,H),(4-619,i-Bu,F-7,O,S,O,5-OH-2-Adm,H),(4-620,i-Bu,F-8,O,S,O,5-OH-2-Adm,H),(4-621,i-Bu,F-9,O,S,O,5-OH-2-Adm,H),(4-622,i-Bu,F-10,O,S,O,5-OH-2-Adm,H),(4-623,i-Bu,F-11,O,S,O,5-OH-2-Adm,H),(4-624,i-Bu,F-12,O,S,O,5-OH-2-Adm,H),(4-625,i-Bu,F-13,O,S,O,5-OH-2-Adm,H),(4-626,i-Bu,F-14,O,S,O,5-OH-2-Adm,H),(4-627,i-Bu,F-15,O,S,O,5-OH-2-Adm,H),(4-628,i-Bu,F-16,O,S,O,5-OH-2-Adm,H),(4-629,i-Bu,F-17,O,S,O,5-OH-2-Adm,H),(4-630,i-Bu,F-18,O,S,O,5-OH-2-Adm,H),(4-631,i-Bu,F-19,O,S,O,5-OH-2-Adm,H),(4-632,i-Bu,F-20,O,S,O,5-OH-2-Adm,H),(4-633,i-Bu,F-21,O,S,O,5-OH-2-Adm,H),(4-634,i-Bu,F-22,O,S,O,5-OH-2-Adm,H),(4-635,i-Bu,F-23,O,S,O,5-OH-2-Adm,H),(4-636,i-Bu,F-24,O,S,O,5-OH-2-Adm,H),(4-637,i-Bu,F-25,O,S,O,5-OH-2-Adm,H),(4-638,i-Bu,F-26,O,S,O,5-OH-2-Adm,H),(4-639,i-Bu,F-27,O,S,O,5-OH-2-Adm,H),(4-640,i-Bu,F-28,O,S,O,5-OH-2-Adm,H),(4-641,i-Bu,F-29,O,S,O,5-OH-2-Adm,H),(4-642,i-Bu,F-30,O,S,O,5-OH-2-Adm,H),(4-643,i-Bu,F-31,O,S,O,5-OH-2-Adm,H),(4-644,i-Bu,F-32,O,S,O,5-OH-2-Adm,H),(4-645,i-Bu,F-33,O,S,O,5-OH-2-Adm,H),(4-646,i-Bu,F-34,O,S,O,5-OH-2-Adm,H),(4-647,i-Bu,F-35,O,S,O,5-OH-2-Adm,H),(4-648,i-Bu,F-36,O,S,O,5-OH-2-Adm,H),(4-649,i-Bu,G-1,O,S,O,1-Adm,H),(4-650,i-Bu,G-2,O,S,O,1-Adm,H),(4-651,i-Bu,G-3,O,S,O,1-Adm,H),(4-652,i-Bu,G-4,O,S,O,1-Adm,H),(4-653,i-Bu,G-5,O,S,O,1-Adm,H),(4-654,i-Bu,G-6,O,S,O,1-Adm,H),(4-655,i-Bu,G-7,O,S,O,1-Adm,H),(4-656,i-Bu,G-8,O,S,O,1-Adm,H),(4-657,i-Bu,G-9,O,S,O,1-Adm,H),(4-658,i-Bu,G-1,O,S,O,2-Adm,H),(4-659,i-Bu,G-2,O,S,O,2-Adm,H),(4-660,i-Bu,G-3,O,S,O,2-Adm,H),(4-661,i-Bu,G-4,O,S,O,2-Adm,H),(4-662,i-Bu,G-5,O,S,O,2-Adm,H),(4-663,i-Bu,G-6,O,S,O,2-Adm,H),(4-664,i-Bu,G-7,O,S,O,2-Adm,H),(4-665,i-Bu,G-8,O,S,O,2-Adm,H),(4-666,i-Bu,G-9,O,S,O,2-Adm,H),(4-667,i-Bu,G-1,O,S,O,5-OH-2-Adm,H),(4-668,i-Bu,G-2,O,S,O,5-OH-2-Adm,H),(4-669,i-Bu,G-3,O,S,O,5-OH-2-Adm,H),(4-670,i-Bu,G-4,O,S,O,5-OH-2-Adm,H),(4-671,i-Bu,G-5,O,S,O,5-OH-2-Adm,H),(4-672,i-Bu,G-6,O,S,O,5-OH-2-Adm,H),(4-673,i-Bu,G-7,O,S,O,5-OH-2-Adm,H),(4-674,i-Bu,G-8,O,S,O,5-OH-2-Adm,H),(4-675,i-Bu,G-9,O,S,O,5-OH-2-Adm,H),(4-676,i-Bu,H-1,O,S,O,1-Adm,H),(4-677,i-Bu,H-2,O,S,O,1-Adm,H),(4-678,i-Bu,H-3,O,S,O,1-Adm,H),(4-679,i-Bu,H-4,O,S,O,1-Adm,H),(4-680,i-Bu,H-5,O,S,O,1-Adm,H),(4-681,i-Bu,H-6,O,S,O,1-Adm,H),(4-682,i-Bu,H-7,O,S,O,1-Adm,H),(4-683,i-Bu,H-8,O,S,O,1-Adm,H),(4-684,i-Bu,H-9,O,S,O,1-Adm,H),(4-685,i-Bu,H-1,O,S,O,2-Adm,H),(4-686,i-Bu,H-2,O,S,O,2-Adm,H),(4-687,i-Bu,H-3,O,S,O,2-Adm,H),(4-688,i-Bu,H-4,O,S,O,2-Adm,H),(4-689,i-Bu,H-5,O,S,O,2-Adm,H),(4-690,i-Bu,H-6,O,S,O,2-Adm,H),(4-691,i-Bu,H-7,O,S,O,2-Adm,H),(4-692,i-Bu,H-8,O,S,O,2-Adm,H),(4-693,i-Bu,H-9,O,S,O,2-Adm,H),(4-694,i-Bu,H-1,O,S,O,5-OH-2-Adm,H),(4-695,i-Bu,H-2,O,S,O,5-OH-2-Adm,H),(4-696,i-Bu,H-3,O,S,O,5-OH-2-Adm,H),(4-697,i-Bu,H-4,O,S,O,5-OH-2-Adm,H),(4-698,i-Bu,H-5,O,S,O,5-OH-2-Adm,H),(4-699,i-Bu,H-6,O,S,O,5-OH-2-Adm,H),(4-700,i-Bu,H-7,O,S,O,5-OH-2-Adm,H),(4-701,i-Bu,H-8,O,S,O,5-OH-2-Adm,H),(4-702,i-Bu,H-9,O,S,O,5-OH-2-Adm,H),(4-703,i-Bu,I-1,O,S,O,1-Adm,H),(4-704,i-Bu,I-2,O,S,O,1-Adm,H),(4-705,i-Bu,I-3,O,S,O,1-Adm,H),(4-706,i-Bu,I-4,O,S,O,1-Adm,H),(4-707,i-Bu,I-5,O,S,O,1-Adm,H),(4-708,i-Bu,I-6,O,S,O,1-Adm,H),(4-709,i-Bu,I-7,O,S,O,1-Adm,H),(4-710,i-Bu,I-8,O,S,O,1-Adm,H),(4-711,i-Bu,I-9,O,S,O,1-Adm,H),(4-712,i-Bu,I-1,O,S,O,2-Adm,H),(4-713,i-Bu,I-2,O,S,O,2-Adm,H),(4-714,i-Bu,I-3,O,S,O,2-Adm,H),(4-715,i-Bu,I-4,O,S,O,2-Adm,H),(4-716,i-Bu,I-5,O,S,O,2-Adm,H),(4-717,i-Bu,I-6,O,S,O,2-Adm,H),(4-718,i-Bu,I-7,O,S,O,2-Adm,H),(4-719,i-Bu,I-8,O,S,O,2-Adm,H),(4-720,i-Bu,I-9,O,S,O,2-Adm,H),(4-721,i-Bu,I-1,O,S,O,5-OH-2-Adm,H),(4-722,i-Bu,I-2,O,S,O,5-OH-2-Adm,H),(4-723,i-Bu,I-3,O,S,O,5-OH-2-Adm,H),(4-724,i-Bu,I-4,O,S,O,5-OH-2-Adm,H),(4-725,i-Bu,I-5,O,S,O,5-OH-2-Adm,H),(4-726,i-Bu,I-6,O,S,O,5-OH-2-Adm,H),(4-727,i-Bu,I-7,O,S,O,5-OH-2-Adm,H),(4-728,i-Bu,I-8,O,S,O,5-OH-2-Adm,H),(4-729,i-Bu,I-9,O,S,O,5-OH-2-Adm,H),(4-730,i-Bu,J-1,O,S,O,1-Adm,H),(4-731,i-Bu,J-2,O,S,O,1-Adm,H),(4-732,i-Bu,J-3,O,S,O,1-Adm,H),(4-733,i-Bu,J-4,O,S,O,1-Adm,H),(4-734,i-Bu,J-5,O,S,O,1-Adm,H),(4-735,i-Bu,J-6,O,S,O,1-Adm,H),(4-736,i-Bu,J-7,O,S,O,1-Adm,H),(4-737,i-Bu,J-8,O,S,O,1-Adm,H),(4-738,i-Bu,J-9,O,S,O,1-Adm,H),(4-739,i-Bu,J-1,O,S,O,2-Adm,H),(4-740,i-Bu,J-2,O,S,O,2-Adm,H),(4-741,i-Bu,J-3,O,S,O,2-Adm,H),(4-742,i-Bu,J-4,O,S,O,2-Adm,H),(4-743,i-Bu,J-5,O,S,O,2-Adm,H),(4-744,i-Bu,J-6,O,S,O,2-Adm,H),(4-745,i-Bu,J-7,O,S,O,2-Adm,H),(4-746,i-Bu,J-8,O,S,O,2-Adm,H),(4-747,i-Bu,J-9,O,S,O,2-Adm,H),(4-748,i-Bu,J-1,O,S,O,5-OH-2-Adm,H),(4-749,i-Bu,J-2,O,S,O,5-OH-2-Adm,H),(4-750,i-Bu,J-3,O,S,O,5-OH-2-Adm,H),(4-751,i-Bu,J-4,O,S,O,5-OH-2-Adm,H),(4-752,i-Bu,J-5,O,S,O,5-OH-2-Adm,H),(4-753,i-Bu,J-6,O,S,O,5-OH-2-Adm,H),(4-754,i-Bu,J-7,O,S,O,5-OH-2-Adm,H),(4-755,i-Bu,J-8,O,S,O,5-OH-2-Adm,H),(4-756,i-Bu,J-9,O,S,O,5-OH-2-Adm,H),(4-757,i-Bu,K-1,O,S,O,1-Adm,H),(4-758,i-Bu,K-2,O,S,O,1-Adm,H),(4-759,i-Bu,K-3,O,S,O,1-Adm,H),(4-760,i-Bu,K-4,O,S,O,1-Adm,H),(4-761,i-Bu,K-5,O,S,O,1-Adm,H),(4-762,i-Bu,K-6,O,S,O,1-Adm,H),(4-763,i-Bu,K-7,O,S,O,1-Adm,H),(4-764,i-Bu,K-8,O,S,O,1-Adm,H),(4-765,i-Bu,K-9,O,S,O,1-Adm,H),(4-766,i-Bu,K-1,O,S,O,2-Adm,H),(4-767,i-Bu,K-2,O,S,O,2-Adm,H),(4-768,i-Bu,K-3,O,S,O,2-Adm,H),(4-769,i-Bu,K-4,O,S,O,2-Adm,H),(4-770,i-Bu,K-5,O,S,O,2-Adm,H),(4-771,i-Bu,K-6,O,S,O,2-Adm,H),(4-772,i-Bu,K-7,O,S,O,2-Adm,H),(4-773,i-Bu,K-8,O,S,O,2-Adm,H),(4-774,i-Bu,K-9,O,S,O,2-Adm,H),(4-775,i-Bu,K-1,O,S,O,5-OH-2-Adm,H),(4-776,i-Bu,K-2,O,S,O,5-OH-2-Adm,H),(4-777,i-Bu,K-3,O,S,O,5-OH-2-Adm,H),(4-778,i-Bu,K-4,O,S,O,5-OH-2-Adm,H),(4-779,i-Bu,K-5,O,S,O,5-OH-2-Adm,H),(4-780,i-Bu,K-6,O,S,O,5-OH-2-Adm,H),(4-781,i-Bu,K-7,O,S,O,5-OH-2-Adm,H),(4-782,i-Bu,K-8,O,S,O,5-OH-2-Adm,H),(4-783,i-Bu,K-9,O,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(5-1,i-Pro,A-1,O,S,O,1-Adm,H),(5-2,i-Pro,A-2,O,S,O,1-Adm,H),(5-3,i-Pro,A-3,O,S,O,1-Adm,H),(5-4,i-Pro,A-4,O,S,O,1-Adm,H),(5-5,i-Pro,A-5,O,S,O,1-Adm,H),(5-6,i-Pro,A-6,O,S,O,1-Adm,H),(5-7,i-Pro,A-7,O,S,O,1-Adm,H),(5-8,i-Pro,A-8,O,S,O,1-Adm,H),(5-9,i-Pro,A-9,O,S,O,1-Adm,H),(5-10,i-Pro,A-10,O,S,O,1-Adm,H),(5-11,i-Pro,A-13,O,S,O,1-Adm,H),(5-12,i-Pro,A-12,O,S,O,1-Adm,H),(5-13,i-Pro,A-13,O,S,O,1-Adm,H),(5-14,i-Pro,A-14,O,S,O,1-Adm,H),(5-15,i-Pro,A-15,O,S,O,1-Adm,H),(5-16,i-Pro,A-16,O,S,O,1-Adm,H),(5-17,i-Pro,A-17,O,S,O,1-Adm,H),(5-18,i-Pro,A-18,O,S,O,1-Adm,H),(5-19,i-Pro,A-19,O,S,O,1-Adm,H),(5-20,i-Pro,A-20,O,S,O,1-Adm,H),(5-21,i-Pro,A-21,O,S,O,1-Adm,H),(5-22,i-Pro,A-22,O,S,O,1-Adm,H),(5-23,i-Pro,A-23,O,S,O,1-Adm,H),(5-24,i-Pro,A-24,O,S,O,1-Adm,H),(5-25,i-Pro,A-25,O,S,O,1-Adm,H),(5-26,i-Pro,A-26,O,S,O,1-Adm,H),(5-27,i-Pro,A-27,O,S,O,1-Adm,H),(5-28,i-Pro,A-28,O,S,O,1-Adm,H),(5-29,i-Pro,A-29,O,S,O,1-Adm,H),(5-30,i-Pro,A-30,O,S,O,1-Adm,H),(5-31,i-Pro,A-31,O,S,O,1-Adm,H),(5-32,i-Pro,A-32,O,S,O,1-Adm,H),(5-33,i-Pro,A-33,O,S,O,1-Adm,H),(5-34,i-Pro,A-34,O,S,O,1-Adm,H),(5-35,i-Pro,A-35,O,S,O,1-Adm,H),(5-36,i-Pro,A-36,O,S,O,1-Adm,H),(5-37,i-Pro,A-1,O,S,O,2-Adm,H),(5-38,i-Pro,A-2,O,S,O,2-Adm,H),(5-39,i-Pro,A-3,O,S,O,2-Adm,H),(5-40,i-Pro,A-4,O,S,O,2-Adm,H),(5-41,i-Pro,A-5,O,S,O,2-Adm,H),(5-42,i-Pro,A-6,O,S,O,2-Adm,H),(5-43,i-Pro,A-7,O,S,O,2-Adm,H),(5-44,i-Pro,A-8,O,S,O,2-Adm,H),(5-45,i-Pro,A-9,O,S,O,2-Adm,H),(5-46,i-Pro,A-10,O,S,O,2-Adm,H),(5-47,i-Pro,A-11,O,S,O,2-Adm,H),(5-48,i-Pro,A-12,O,S,O,2-Adm,H),(5-49,i-Pro,A-13,O,S,O,2-Adm,H),(5-50,i-Pro,A-14,O,S,O,2-Adm,H),(5-51,i-Pro,A-15,O,S,O,2-Adm,H),(5-52,i-Pro,A-16,O,S,O,2-Adm,H),(5-53,i-Pro,A-17,O,S,O,2-Adm,H),(5-54,i-Pro,A-18,O,S,O,2-Adm,H),(5-55,i-Pro,A-19,O,S,O,2-Adm,H),(5-56,i-Pro,A-20,O,S,O,2-Adm,H),(5-57,i-Pro,A-21,O,S,O,2-Adm,H),(5-58,i-Pro,A-22,O,S,O,2-Adm,H),(5-59,i-Pro,A-23,O,S,O,2-Adm,H),(5-60,i-Pro,A-24,O,S,O,2-Adm,H),(5-61,i-Pro,A-25,O,S,O,2-Adm,H),(5-62,i-Pro,A-26,O,S,O,2-Adm,H),(5-63,i-Pro,A-27,O,S,O,2-Adm,H),(5-64,i-Pro,A-28,O,S,O,2-Adm,H),(5-65,i-Pro,A-29,O,S,O,2-Adm,H),(5-66,i-Pro,A-30,O,S,O,2-Adm,H),(5-67,i-Pro,A-31,O,S,O,2-Adm,H),(5-68,i-Pro,A-32,O,S,O,2-Adm,H),(5-69,i-Pro,A-33,O,S,O,2-Adm,H),(5-70,i-Pro,A-34,O,S,O,2-Adm,H),(5-71,i-Pro,A-35,O,S,O,2-Adm,H),(5-72,i-Pro,A-36,O,S,O,2-Adm,H),(5-73,i-Pro,A-1,O,S,O,5-OH-2-Adm,H),(5-74,i-Pro,A-2,O,S,O,5-OH-2-Adm,H),(5-75,i-Pro,A-3,O,S,O,5-OH-2-Adm,H),(5-76,i-Pro,A-4,O,S,O,5-OH-2-Adm,H),(5-77,i-Pro,A-5,O,S,O,5-OH-2-Adm,H),(5-78,i-Pro,A-6,O,S,O,5-OH-2-Adm,H),(5-79,i-Pro,A-7,O,S,O,5-OH-2-Adm,H),(5-80,i-Pro,A-8,O,S,O,5-OH-2-Adm,H),(5-81,i-Pro,A-9,O,S,O,5-OH-2-Adm,H),(5-82,i-Pro,A-10,O,S,O,5-OH-2-Adm,H),(5-83,i-Pro,A-11,O,S,O,5-OH-2-Adm,H),(5-84,i-Pro,A-12,O,S,O,5-OH-2-Adm,H),(5-85,i-Pro,A-13,O,S,O,5-OH-2-Adm,H),(5-86,i-Pro,A-14,O,S,O,5-OH-2-Adm,H),(5-87,i-Pro,A-15,O,S,O,5-OH-2-Adm,H),(5-88,i-Pro,A-16,O,S,O,5-OH-2-Adm,H),(5-89,i-Pro,A-17,O,S,O,5-OH-2-Adm,H),(5-90,i-Pro,A-18,O,S,O,5-OH-2-Adm,H),(5-91,i-Pro,A-19,O,S,O,5-OH-2-Adm,H),(5-92,i-Pro,A-20,O,S,O,5-OH-2-Adm,H),(5-93,i-Pro,A-21,O,S,O,5-OH-2-Adm,H),(5-94,i-Pro,A-22,O,S,O,5-OH-2-Adm,H),(5-95,i-Pro,A-23,O,S,O,5-OH-2-Adm,H),(5-96,i-Pro,A-24,O,S,O,5-OH-2-Adm,H),(5-97,i-Pro,A-25,O,S,O,5-OH-2-Adm,H),(5-98,i-Pro,A-26,O,S,O,5-OH-2-Adm,H),(5-99,i-Pro,A-27,O,S,O,5-OH-2-Adm,H),(5-100,i-Pro,A-28,O,S,O,5-OH-2-Adm,H),(5-101,i-Pro,A-29,O,S,O,5-OH-2-Adm,H),(5-102,i-Pro,A-30,O,S,O,5-OH-2-Adm,H),(5-103,i-Pro,A-31,O,S,O,5-OH-2-Adm,H),(5-104,i-Pro,A-32,O,S,O,5-OH-2-Adm,H),(5-105,i-Pro,A-33,O,S,O,5-OH-2-Adm,H),(5-106,i-Pro,A-34,O,S,O,5-OH-2-Adm,H),(5-107,i-Pro,A-35,O,S,O,5-OH-2-Adm,H),(5-108,i-Pro,A-36,O,S,O,5-OH-2-Adm,H),(5-119,i-Pro,B-1,O,S,O,1-Adm,H),(5-110,i-Pro,B-2,O,S,O,1-Adm,H),(5-111,i-Pro,B-3,O,S,O,1-Adm,H),(5-112,i-Pro,B-4,O,S,O,1-Adm,H),(5-113,i-Pro,B-5,O,S,O,1-Adm,H),(5-114,i-Pro,B-6,O,S,O,1-Adm,H),(5-115,i-Pro,B-7,O,S,O,1-Adm,H),(5-116,i-Pro,B-8,O,S,O,1-Adm,H),(5-117,i-Pro,B-9,O,S,O,1-Adm,H),(5-118,i-Pro,B-11,O,S,O,1-Adm,H),(5-119,i-Pro,B-11,O,S,O,1-Adm,H),(5-120,i-Pro,B-12,O,S,O,1-Adm,H),(5-121,i-Pro,B-13,O,S,O,1-Adm,H),(5-122,i-Pro,B-14,O,S,O,1-Adm,H),(5-123,i-Pro,B-15,O,S,O,1-Adm,H),(5-124,i-Pro,B-16,O,S,O,1-Adm,H),(5-125,i-Pro,B-17,O,S,O,1-Adm,H),(5-126,i-Pro,B-18,O,S,O,1-Adm,H),(5-127,i-Pro,B-19,O,S,O,1-Adm,H),(5-128,i-Pro,B-20,O,S,O,1-Adm,H),(5-129,i-Pro,B-21,O,S,O,1-Adm,H),(5-130,i-Pro,B-22,O,S,O,1-Adm,H),(5-131,i-Pro,B-23,O,S,O,1-Adm,H),(5-132,i-Pro,B-24,O,S,O,1-Adm,H),(5-133,i-Pro,B-25,O,S,O,1-Adm,H),(5-134,i-Pro,B-26,O,S,O,1-Adm,H),(5-13,i-Pro,B-27,O,S,O,1-Adm,H),(5-136,i-Pro,B-28,O,S,O,1-Adm,H),(5-137,i-Pro,B-29,O,S,O,1-Adm,H),(5-138,i-Pro,B-30,O,S,O,1-Adm,H),(5-139,i-Pro,B-31,O,S,O,1-Adm,H),(5-140,i-Pro,B-32,O,S,O,1-Adm,H),(5-141,i-Pro,B-33,O,S,O,1-Adm,H),(5-142,i-Pro,B-34,O,S,O,1-Adm,H),(5-143,i-Pro,B-35,O,S,O,1-Adm,H),(5-144,i-Pro,B-36,O,S,O,1-Adm,H),(5-145,i-Pro,B-1,O,S,O,2-Adm,H),(5-146,i-Pro,B-2,O,S,O,2-Adm,H),(5-147,i-Pro,B-3,O,S,O,2-Adm,H),(5-148,i-Pro,B-4,O,S,O,2-Adm,H),(5-149,i-Pro,B-5,O,S,O,2-Adm,H),(5-150,i-Pro,B-6,O,S,O,2-Adm,H),(5-151,i-Pro,B-7,O,S,O,2-Adm,H),(5-152,i-Pro,B-8,O,S,O,2-Adm,H),(5-153,i-Pro,B-9,O,S,O,2-Adm,H),(5-154,i-Pro,B-10,O,S,O,2-Adm,H),(5-155,i-Pro,B-11,O,S,O,2-Adm,H),(5-156,i-Pro,B-12,O,S,O,2-Adm,H),(5-157,i-Pro,B-13,O,S,O,2-Adm,H),(5-158,i-Pro,B-14,O,S,O,2-Adm,H),(5-159,i-Pro,B-15,O,S,O,2-Adm,H),(5-160,i-Pro,B-16,O,S,O,2-Adm,H),(5-161,i-Pro,B-17,O,S,O,2-Adm,H),(5-162,i-Pro,B-18,O,S,O,2-Adm,H),(5-163,i-Pro,B-119,O,S,O,2-Adm,H),(5-164,i-Pro,B-20,O,S,O,2-Adm,H),(5-165,i-Pro,B-21,O,S,O,2-Adm,H),(5-166,i-Pro,B-22,O,S,O,2-Adm,H),(5-167,i-Pro,B-23,O,S,O,2-Adm,H),(5-168,i-Pro,B-24,O,S,O,2-Adm,H),(5-169,i-Pro,B-25,O,S,O,2-Adm,H),(5-170,i-Pro,B-26,O,S,O,2-Adm,H),(5-171,i-Pro,B-27,O,S,O,2-Adm,H),(5-172,i-Pro,B-28,O,S,O,2-Adm,H),(5-173,i-Pro,B-29,O,S,O,2-Adm,H),(5-174,i-Pro,B-30,O,S,O,2-Adm,H),(5-175,i-Pro,B-31,O,S,O,2-Adm,H),(5-176,i-Pro,B-32,O,S,O,2-Adm,H),(5-177,i-Pro,B-33,O,S,O,2-Adm,H),(5-178,i-Pro,B-34,O,S,O,2-Adm,H),(5-179,i-Pro,B-35,O,S,O,2-Adm,H),(5-180,i-Pro,B-36,O,S,O,2-Adm,H),(5-181,i-Pro,B-11,O,S,O,5-OH-2-Adm,H),(5-182,i-Pro,B-2,O,S,O,5-OH-2-Adm,H),(5-183,i-Pro,B-3,O,S,O,5-OH-2-Adm,H),(5-184,i-Pro,B-4,O,S,O,5-OH-2-Adm,H),(5-185,i-Pro,B-5,O,S,O,5-OH-2-Adm,H),(5-186,i-Pro,B-6,O,S,O,5-OH-2-Adm,H),(5-187,i-Pro,B-7,O,S,O,5-OH-2-Adm,H),(5-188,i-Pro,B-8,O,S,O,5-OH-2-Adm,H),(5-189,i-Pro,B-9,O,S,O,5-OH-2-Adm,H),(5-190,i-Pro,B-10,O,S,O,5-OH-2-Adm,H),(5-191,i-Pro,B-11,O,S,O,5-OH-2-Adm,H),(5-192,i-Pro,B-12,O,S,O,5-OH-2-Adm,H),(5-193,i-Pro,B-13,O,S,O,5-OH-2-Adm,H),(5-194,i-Pro,B-14,O,S,O,5-OH-2-Adm,H),(5-195,i-Pro,B-15,O,S,O,5-OH-2-Adm,H),(5-196,i-Pro,B-16,O,S,O,5-OH-2-Adm,H),(5-197,i-Pro,B-17,O,S,O,5-OH-2-Adm,H),(5-198,i-Pro,B-18,O,S,O,5-OH-2-Adm,H),(5-1199,i-Pro,B-119,O,S,O,5-OH-2-Adm,H),(5-200,i-Pro,B-20,O,S,O,5-OH-2-Adm,H),(5-201,i-Pro,B-21,O,S,O,5-OH-2-Adm,H),(5-202,i-Pro,B-22,O,S,O,5-OH-2-Adm,H),(5-203,i-Pro,B-23,O,S,O,5-OH-2-Adm,H),(5-204,i-Pro,B-24,O,S,O,5-OH-2-Adm,H),(5-205,i-Pro,B-25,O,S,O,5-OH-2-Adm,H),(5-206,i-Pro,B-26,O,S,O,5-OH-2-Adm,H),(5-207,i-Pro,B-27,O,S,O,5-OH-2-Adm,H),(5-208,i-Pro,B-28,O,S,O,5-OH-2-Adm,H),(5-209,i-Pro,B-29,O,S,O,5-OH-2-Adm,H),(5-210,i-Pro,B-30,O,S,O,5-OH-2-Adm,H),(5-211,i-Pro,B-31,O,S,O,5-OH-2-Adm,H),(5-212,i-Pro,B-32,O,S,O,5-OH-2-Adm,H),(5-213,i-Pro,B-33,O,S,O,5-OH-2-Adm,H),(5-214,i-Pro,B-34,O,S,O,5-OH-2-Adm,H),(5-215,i-Pro,B-35,O,S,O,5-OH-2-Adm,H),(5-216,i-Pro,B-36,O,S,O,5-OH-2-Adm,H),(5-217,i-Pro,C-1,O,S,O,1-Adm,H),(5-218,i-Pro,C-2,O,S,O,1-Adm,H),(5-219,i-Pro,C-3,O,S,O,1-Adm,H),(5-220,i-Pro,C-4,O,S,O,1-Adm,H),(5-221,i-Pro,C-5,O,S,O,1-Adm,H),(5-222,i-Pro,C-6,O,S,O,1-Adm,H),(5-223,i-Pro,C-7,O,S,O,1-Adm,H),(5-224,i-Pro,C-8,O,S,O,1-Adm,H),(5-225,i-Pro,C-9,O,S,O,1-Adm,H),(5-226,i-Pro,C-11,O,S,O,1-Adm,H),(5-227,i-Pro,C-11,O,S,O,1-Adm,H),(5-228,i-Pro,C-12,O,S,O,1-Adm,H),(5-229,i-Pro,C-13,O,S,O,1-Adm,H),(5-230,i-Pro,C-14,O,S,O,1-Adm,H),(5-231,i-Pro,C-15,O,S,O,1-Adm,H),(5-232,i-Pro,C-16,O,S,O,1-Adm,H),(5-233,i-Pro,C-17,O,S,O,1-Adm,H),(5-234,i-Pro,C-18,O,S,O,1-Adm,H),(5-235,i-Pro,C-19,O,S,O,1-Adm,H),(5-236,i-Pro,C-20,O,S,O,1-Adm,H),(5-237,i-Pro,C-21,O,S,O,1-Adm,H),(5-238,i-Pro,C-22,O,S,O,1-Adm,H),(5-239,i-Pro,C-23,O,S,O,1-Adm,H),(5-240,i-Pro,C-24,O,S,O,1-Adm,H),(5-241,i-Pro,C-25,O,S,O,1-Adm,H),(5-242,i-Pro,C-26,O,S,O,1-Adm,H),(5-243,i-Pro,C-27,O,S,O,1-Adm,H),(5-244,i-Pro,C-28,O,S,O,1-Adm,H),(5-245,i-Pro,C-29,O,S,O,1-Adm,H),(5-246,i-Pro,C-30,O,S,O,1-Adm,H),(5-247,i-Pro,C-31,O,S,O,1-Adm,H),(5-248,i-Pro,C-32,O,S,O,1-Adm,H),(5-249,i-Pro,C-33,O,S,O,1-Adm,H),(5-250,i-Pro,C-34,O,S,O,1-Adm,H),(5-251,i-Pro,C-35,O,S,O,1-Adm,H),(5-252,i-Pro,C-36,O,S,O,1-Adm,H),(5-253,i-Pro,C-1,O,S,O,2-Adm,H),(5-254,i-Pro,C-2,O,S,O,2-Adm,H),(5-255,i-Pro,C-3,O,S,O,2-Adm,H),(5-256,i-Pro,C-4,O,S,O,2-Adm,H),(5-257,i-Pro,C-5,O,S,O,2-Adm,H),(5-258,i-Pro,C-6,O,S,O,2-Adm,H),(5-259,i-Pro,C-7,O,S,O,2-Adm,H),(5-260,i-Pro,C-8,O,S,O,2-Adm,H),(5-261,i-Pro,C-9,O,S,O,2-Adm,H),(5-262,i-Pro,C-10,O,S,O,2-Adm,H),(5-263,i-Pro,C-11,O,S,O,2-Adm,H),(5-264,i-Pro,C-12,O,S,O,2-Adm,H),(5-265,i-Pro,C-13,O,S,O,2-Adm,H),(5-266,i-Pro,C-14,O,S,O,2-Adm,H),(5-267,i-Pro,C-15,O,S,O,2-Adm,H),(5-268,i-Pro,C-16,O,S,O,2-Adm,H),(5-269,i-Pro,C-17,O,S,O,2-Adm,H),(5-270,i-Pro,C-18,O,S,O,2-Adm,H),(5-271,i-Pro,C-19,O,S,O,2-Adm,H),(5-272,i-Pro,C-20,O,S,O,2-Adm,H),(5-273,i-Pro,C-21,O,S,O,2-Adm,H),(5-274,i-Pro,C-22,O,S,O,2-Adm,H),(5-275,i-Pro,C-23,O,S,O,2-Adm,H),(5-276,i-Pro,C-24,O,S,O,2-Adm,H),(5-277,i-Pro,C-25,O,S,O,2-Adm,H),(5-278,i-Pro,C-26,O,S,O,2-Adm,H),(5-279,i-Pro,C-27,O,S,O,2-Adm,H),(5-280,i-Pro,C-28,O,S,O,2-Adm,H),(5-281,i-Pro,C-29,O,S,O,2-Adm,H),(5-282,i-Pro,C-30,O,S,O,2-Adm,H),(5-283,i-Pro,C-31,O,S,O,2-Adm,H),(5-284,i-Pro,C-32,O,S,O,2-Adm,H),(5-285,i-Pro,C-33,O,S,O,2-Adm,H),(5-286,i-Pro,C-34,O,S,O,2-Adm,H),(5-287,i-Pro,C-35,O,S,O,2-Adm,H),(5-288,i-Pro,C-36,O,S,O,2-Adm,H),(5-289,i-Pro,C-1,O,S,O,5-OH-2-Adm,H),(5-290,i-Pro,C-2,O,S,O,5-OH-2-Adm,H),(5-291,i-Pro,C-3,O,S,O,5-OH-2-Adm,H),(5-292,i-Pro,C-4,O,S,O,5-OH-2-Adm,H),(5-293,i-Pro,C-5,O,S,O,5-OH-2-Adm,H),(5-294,i-Pro,C-6,O,S,O,5-OH-2-Adm,H),(5-295,i-Pro,C-7,O,S,O,5-OH-2-Adm,H),(5-296,i-Pro,C-8,O,S,O,5-OH-2-A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,S,O,1-Adm,H),(5-732,i-Pro,J-3,O,S,O,1-Adm,H),(5-733,i-Pro,J-4,O,S,O,1-Adm,H),(5-734,i-Pro,J-5,O,S,O,1-Adm,H),(5-735,i-Pro,J-6,O,S,O,1-Adm,H),(5-736,i-Pro,J-7,O,S,O,1-Adm,H),(5-737,i-Pro,J-8,O,S,O,1-Adm,H),(5-738,i-Pro,J-9,O,S,O,1-Adm,H),(5-739,i-Pro,J-1,O,S,O,2-Adm,H),(5-740,i-Pro,J-2,O,S,O,2-Adm,H),(5-741,i-Pro,J-3,O,S,O,2-Adm,H),(5-742,i-Pro,J-4,O,S,O,2-Adm,H),(5-743,i-Pro,J-5,O,S,O,2-Adm,H),(5-744,i-Pro,J-6,O,S,O,2-Adm,H),(5-745,i-Pro,J-7,O,S,O,2-Adm,H),(5-746,i-Pro,J-8,O,S,O,2-Adm,H),(5-747,i-Pro,J-9,O,S,O,2-Adm,H),(5-748,i-Pro,J-1,O,S,O,5-OH-2-Adm,H),(5-749,i-Pro,J-2,O,S,O,5-OH-2-Adm,H),(5-750,i-Pro,J-3,O,S,O,5-OH-2-Adm,H),(5-751,i-Pro,J-4,O,S,O,5-OH-2-Adm,H),(5-752,i-Pro,J-5,O,S,O,5-OH-2-Adm,H),(5-753,i-Pro,J-6,O,S,O,5-OH-2-Adm,H),(5-754,i-Pro,J-7,O,S,O,5-OH-2-Adm,H),(5-755,i-Pro,J-8,O,S,O,5-OH-2-Adm,H),(5-756,i-Pro,J-9,O,S,O,5-OH-2-Adm,H),(5-757,i-Pro,K-1,O,S,O,1-Adm,H),(5-758,i-Pro,K-2,O,S,O,1-Adm,H),(5-759,i-Pro,K-3,O,S,O,1-Adm,H),(5-760,i-Pro,K-4,O,S,O,1-Adm,H),(5-761,i-Pro,K-5,O,S,O,1-Adm,H),(5-762,i-Pro,K-6,O,S,O,1-Adm,H),(5-763,i-Pro,K-7,O,S,O,1-Adm,H),(5-764,i-Pro,K-8,O,S,O,1-Adm,H),(5-765,i-Pro,K-9,O,S,O,1-Adm,H),(5-766,i-Pro,K-1,O,S,O,2-Adm,H),(5-767,i-Pro,K-2,O,S,O,2-Adm,H),(5-768,i-Pro,K-3,O,S,O,2-Adm,H),(5-769,i-Pro,K-4,O,S,O,2-Adm,H),(5-770,i-Pro,K-5,O,S,O,2-Adm,H),(5-771,i-Pro,K-6,O,S,O,2-Adm,H),(5-772,i-Pro,K-7,O,S,O,2-Adm,H),(5-773,i-Pro,K-8,O,S,O,2-Adm,H),(5-774,i-Pro,K-9,O,S,O,2-Adm,H),(5-775,i-Pro,K-1,O,S,O,5-OH-2-Adm,H),(5-776,i-Pro,K-2,O,S,O,5-OH-2-Adm,H),(5-777,i-Pro,K-3,O,S,O,5-OH-2-Adm,H),(5-778,i-Pro,K-4,O,S,O,5-OH-2-Adm,H),(5-779,i-Pro,K-5,O,S,O,5-OH-2-Adm,H),(5-780,i-Pro,K-6,O,S,O,5-OH-2-Adm,H),(5-781,i-Pro,K-7,O,S,O,5-OH-2-Adm,H),(5-782,i-Pro,K-8,O,S,O,5-OH-2-Adm,H),(5-783,i-Pro,K-9,O,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(6-1,Pro,A-1,O,S,O,1-Adm,H),(6-2,Pro,A-2,O,S,O,1-Adm,H),(6-3,Pro,A-3,O,S,O,1-Adm,H),(6-4,Pro,A-4,O,S,O,1-Adm,H),(6-5,Pro,A-5,O,S,O,1-Adm,H),(6-6,Pro,A-6,O,S,O,1-Adm,H),(6-7,Pro,A-7,O,S,O,1-Adm,H),(6-8,Pro,A-8,O,S,O,1-Adm,H),(6-9,Pro,A-9,O,S,O,1-Adm,H),(6-10,Pro,A-10,O,S,O,1-Adm,H),(6-11,Pro,A-11,O,S,O,1-Adm,H),(6-12,Pro,A-12,O,S,O,1-Adm,H),(6-13,Pro,A-13,O,S,O,1-Adm,H),(6-14,Pro,A-14,O,S,O,1-Adm,H),(6-15,Pro,A-15,O,S,O,1-Adm,H),(6-16,Pro,A-16,O,S,O,1-Adm,H),(6-17,Pro,A-17,O,S,O,1-Adm,H),(6-18,Pro,A-18,O,S,O,1-Adm,H),(6-19,Pro,A-19,O,S,O,1-Adm,H),(6-20,Pro,A-20,O,S,O,1-Adm,H),(6-21,Pro,A-21,O,S,O,1-Adm,H),(6-22,Pro,A-22,O,S,O,1-Adm,H),(6-23,Pro,A-23,O,S,O,1-Adm,H),(6-24,Pro,A-24,O,S,O,1-Adm,H),(6-25,Pro,A-25,O,S,O,1-Adm,H),(6-26,Pro,A-26,O,S,O,1-Adm,H),(6-27,Pro,A-27,O,S,O,1-Adm,H),(6-28,Pro,A-28,O,S,O,1-Adm,H),(6-29,Pro,A-29,O,S,O,1-Adm,H),(6-30,Pro,A-30,O,S,O,1-Adm,H),(6-31,Pro,A-31,O,S,O,1-Adm,H),(6-32,Pro,A-32,O,S,O,1-Adm,H),(6-33,Pro,A-33,O,S,O,1-Adm,H),(6-34,Pro,A-34,O,S,O,1-Adm,H),(6-35,Pro,A-35,O,S,O,1-Adm,H),(6-36,Pro,A-36,O,S,O,1-Adm,H),(6-37,Pro,A-1,O,S,O,2-Adm,H),(6-38,Pro,A-2,O,S,O,2-Adm,H),(6-39,Pro,A-3,O,S,O,2-Adm,H),(6-40,Pro,A-4,O,S,O,2-Adm,H),(6-41,Pro,A-5,O,S,O,2-Adm,H),(6-42,Pro,A-6,O,S,O,2-Adm,H),(6-43,Pro,A-7,O,S,O,2-Adm,H),(6-44,Pro,A-8,O,S,O,2-Adm,H),(6-45,Pro,A-9,O,S,O,2-Adm,H),(6-46,Pro,A-11,O,S,O,2-Adm,H),(6-47,Pro,A-11,O,S,O,2-Adm,H),(6-48,Pro,A-12,O,S,O,2-Adm,H),(6-49,Pro,A-13,O,S,O,2-Adm,H),(6-50,Pro,A-14,O,S,O,2-Adm,H),(6-51,Pro,A-15,O,S,O,2-Adm,H),(6-52,Pro,A-16,O,S,O,2-Adm,H),(6-53,Pro,A-17,O,S,O,2-Adm,H),(6-54,Pro,A-18,O,S,O,2-Adm,H),(6-55,Pro,A-19,O,S,O,2-Adm,H),(6-56,Pro,A-20,O,S,O,2-Adm,H),(6-57,Pro,A-21,O,S,O,2-Adm,H),(6-58,Pro,A-22,O,S,O,2-Adm,H),(6-59,Pro,A-23,O,S,O,2-Adm,H),(6-60,Pro,A-24,O,S,O,2-Adm,H),(6-61,Pro,A-25,O,S,O,2-Adm,H),(6-62,Pro,A-26,O,S,O,2-Adm,H),(6-63,Pro,A-27,O,S,O,2-Adm,H),(6-64,Pro,A-28,O,S,O,2-Adm,H),(6-65,Pro,A-29,O,S,O,2-Adm,H),(6-66,Pro,A-30,O,S,O,2-Adm,H),(6-67,Pro,A-31,O,S,O,2-Adm,H),(6-68,Pro,A-32,O,S,O,2-Adm,H),(6-69,Pro,A-33,O,S,O,2-Adm,H),(6-70,Pro,A-34,O,S,O,2-Adm,H),(6-71,Pro,A-35,O,S,O,2-Adm,H),(6-72,Pro,A-36,O,S,O,2-Adm,H),(6-73,Pro,A-1,O,S,O,5-OH-2-Adm,H),(6-74,Pro,A-2,O,S,O,5-OH-2-Adm,H),(6-75,Pro,A-3,O,S,O,5-OH-2-Adm,H),(6-76,Pro,A-4,O,S,O,5-OH-2-Adm,H),(6-77,Pro,A-5,O,S,O,5-OH-2-Adm,H),(6-78,Pro,A-6,O,S,O,5-OH-2-Adm,H),(6-79,Pro,A-7,O,S,O,5-OH-2-Adm,H),(6-80,Pro,A-8,O,S,O,5-OH-2-Adm,H),(6-81,Pro,A-9,O,S,O,5-OH-2-Adm,H),(6-82,Pro,A-10,O,S,O,5-OH-2-Adm,H),(6-83,Pro,A-11,O,S,O,5-OH-2-Adm,H),(6-84,Pro,A-12,O,S,O,5-OH-2-Adm,H),(6-85,Pro,A-13,O,S,O,5-OH-2-Adm,H),(6-86,Pro,A-14,O,S,O,5-OH-2-Adm,H),(6-87,Pro,A-15,O,S,O,5-OH-2-Adm,H),(6-88,Pro,A-16,O,S,O,5-OH-2-Adm,H),(6-89,Pro,A-17,O,S,O,5-OH-2-Adm,H),(6-90,Pro,A-18,O,S,O,5-OH-2-Adm,H),(6-91,Pro,A-19,O,S,O,5-OH-2-Adm,H),(6-92,Pro,A-20,O,S,O,5-OH-2-Adm,H),(6-93,Pro,A-21,O,S,O,5-OH-2-Adm,H),(6-94,Pro,A-22,O,S,O,5-OH-2-Adm,H),(6-95,Pro,A-23,O,S,O,5-OH-2-Adm,H),(6-96,Pro,A-24,O,S,O,5-OH-2-Adm,H),(6-97,Pro,A-25,O,S,O,5-OH-2-Adm,H),(6-98,Pro,A-26,O,S,O,5-OH-2-Adm,H),(6-99,Pro,A-27,O,S,O,5-OH-2-Adm,H),(6-100,Pro,A-28,O,S,O,5-OH-2-Adm,H),(6-101,Pro,A-29,O,S,O,5-OH-2-Adm,H),(6-102,Pro,A-30,O,S,O,5-OH-2-Adm,H),(6-103,Pro,A-31,O,S,O,5-OH-2-Adm,H),(6-104,Pro,A-32,O,S,O,5-OH-2-Adm,H),(6-105,Pro,A-33,O,S,O,5-OH-2-Adm,H),(6-106,Pro,A-34,O,S,O,5-OH-2-Adm,H),(6-107,Pro,A-35,O,S,O,5-OH-2-Adm,H),(6-108,Pro,A-36,O,S,O,5-OH-2-Adm,H),(6-109,Pro,B-1,O,S,O,1-Adm,H),(6-110,Pro,B-2,O,S,O,1-Adm,H),(6-111,Pro,B-3,O,S,O,1-Adm,H),(6-112,Pro,B-4,O,S,O,1-Adm,H),(6-113,Pro,B-5,O,S,O,1-Adm,H),(6-114,Pro,B-6,O,S,O,1-Adm,H),(6-115,Pro,B-7,O,S,O,1-Adm,H),(6-116,Pro,B-8,O,S,O,1-Adm,H),(6-117,Pro,B-9,O,S,O,1-Adm,H),(6-118,Pro,B-10,O,S,O,1-Adm,H),(6-119,Pro,B-11,O,S,O,1-Adm,H),(6-120,Pro,B-12,O,S,O,1-Adm,H),(6-121,Pro,B-13,O,S,O,1-Adm,H),(6-122,Pro,B-14,O,S,O,1-Adm,H),(6-123,Pro,B-15,O,S,O,1-Adm,H),(6-124,Pro,B-16,O,S,O,1-Adm,H),(6-125,Pro,B-17,O,S,O,1-Adm,H),(6-126,Pro,B-18,O,S,O,1-Adm,H),(6-127,Pro,B-19,O,S,O,1-Adm,H),(6-128,Pro,B-20,O,S,O,1-Adm,H),(6-129,Pro,B-21,O,S,O,1-Adm,H),(6-130,Pro,B-22,O,S,O,1-Adm,H),(6-131,Pro,B-23,O,S,O,1-Adm,H),(6-132,Pro,B-24,O,S,O,1-Adm,H),(6-133,Pro,B-25,O,S,O,1-Adm,H),(6-134,Pro,B-26,O,S,O,1-Adm,H),(6-135,Pro,B-27,O,S,O,1-Adm,H),(6-136,Pro,B-28,O,S,O,1-Adm,H),(6-137,Pro,B-29,O,S,O,1-Adm,H),(6-138,Pro,B-30,O,S,O,1-Adm,H),(6-139,Pro,B-31,O,S,O,1-Adm,H),(6-140,Pro,B-32,O,S,O,1-Adm,H),(6-141,Pro,B-33,O,S,O,1-Adm,H),(6-142,Pro,B-34,O,S,O,1-Adm,H),(6-143,Pro,B-35,O,S,O,1-Adm,H),(6-144,Pro,B-36,O,S,O,1-Adm,H),(6-145,Pro,B-1,O,S,O,2-Adm,H),(6-146,Pro,B-2,O,S,O,2-Adm,H),(6-147,Pro,B-3,O,S,O,2-Adm,H),(6-148,Pro,B-4,O,S,O,2-Adm,H),(6-149,Pro,B-5,O,S,O,2-Adm,H),(6-1500,Pro,B-6,O,S,O,2-Adm,H),(6-1511,Pro,B-7,O,S,O,2-Adm,H),(6-152,Pro,B-8,O,S,O,2-Adm,H),(6-153,Pro,B-9,O,S,O,2-Adm,H),(6-154,Pro,B-10,O,S,O,2-Adm,H),(6-155,Pro,B-11,O,S,O,2-Adm,H),(6-156,Pro,B-12,O,S,O,2-Adm,H),(6-157,Pro,B-13,O,S,O,2-Adm,H),(6-158,Pro,B-14,O,S,O,2-Adm,H),(6-159,Pro,B-15,O,S,O,2-Adm,H),(6-160,Pro,B-16,O,S,O,2-Adm,H),(6-161,Pro,B-17,O,S,O,2-Adm,H),(6-162,Pro,B-18,O,S,O,2-Adm,H),(6-163,Pro,B-19,O,S,O,2-Adm,H),(6-164,Pro,B-20,O,S,O,2-Adm,H),(6-165,Pro,B-21,O,S,O,2-Adm,H),(6-166,Pro,B-22,O,S,O,2-Adm,H),(6-167,Pro,B-23,O,S,O,2-Adm,H),(6-168,Pro,B-24,O,S,O,2-Adm,H),(6-169,Pro,B-25,O,S,O,2-Adm,H),(6-170,Pro,B-26,O,S,O,2-Adm,H),(6-171,Pro,B-27,O,S,O,2-Adm,H),(6-172,Pro,B-28,O,S,O,2-Adm,H),(6-173,Pro,B-29,O,S,O,2-Adm,H),(6-174,Pro,B-30,O,S,O,2-Adm,H),(6-175,Pro,B-31,O,S,O,2-Adm,H),(6-176,Pro,B-32,O,S,O,2-Adm,H),(6-177,Pro,B-33,O,S,O,2-Adm,H),(6-178,Pro,B-34,O,S,O,2-Adm,H),(6-179,Pro,B-35,O,S,O,2-Adm,H),(6-180,Pro,B-36,O,S,O,2-Adm,H),(6-181,Pro,B-1,O,S,O,5-OH-2-Adm,H),(6-182,Pro,B-2,O,S,O,5-OH-2-Adm,H),(6-183,Pro,B-3,O,S,O,5-OH-2-Adm,H),(6-184,Pro,B-4,O,S,O,5-OH-2-Adm,H),(6-185,Pro,B-5,O,S,O,5-OH-2-Adm,H),(6-186,Pro,B-6,O,S,O,5-OH-2-Adm,H),(6-187,Pro,B-7,O,S,O,5-OH-2-Adm,H),(6-188,Pro,B-8,O,S,O,5-OH-2-Adm,H),(6-189,Pro,B-9,O,S,O,5-OH-2-Adm,H),(6-190,Pro,B-10,O,S,O,5-OH-2-Adm,H),(6-191,Pro,B-11,O,S,O,5-OH-2-Adm,H),(6-192,Pro,B-12,O,S,O,5-OH-2-Adm,H),(6-193,Pro,B-13,O,S,O,5-OH-2-Adm,H),(6-194,Pro,B-14,O,S,O,5-OH-2-Adm,H),(6-195,Pro,B-15,O,S,O,5-OH-2-Adm,H),(6-196,Pro,B-16,O,S,O,5-OH-2-Adm,H),(6-197,Pro,B-17,O,S,O,5-OH-2-Adm,H),(6-198,Pro,B-18,O,S,O,5-OH-2-Adm,H),(6-199,Pro,B-19,O,S,O,5-OH-2-Adm,H),(6-200,Pro,B-20,O,S,O,5-OH-2-Adm,H),(6-201,Pro,B-21,O,S,O,5-OH-2-Adm,H),(6-202,Pro,B-22,O,S,O,5-OH-2-Adm,H),(6-203,Pro,B-23,O,S,O,5-OH-2-Adm,H),(6-204,Pro,B-24,O,S,O,5-OH-2-Adm,H),(6-205,Pro,B-25,O,S,O,5-OH-2-Adm,H),(6-206,Pro,B-26,O,S,O,5-OH-2-Adm,H),(6-207,Pro,B-27,O,S,O,5-OH-2-Adm,H),(6-208,Pro,B-28,O,S,O,5-OH-2-Adm,H),(6-209,Pro,B-29,O,S,O,5-OH-2-Adm,H),(6-210,Pro,B-30,O,S,O,5-OH-2-Adm,H),(6-211,Pro,B-31,O,S,O,5-OH-2-Adm,H),(6-212,Pro,B-32,O,S,O,5-OH-2-Adm,H),(6-213,Pro,B-33,O,S,O,5-OH-2-Adm,H),(6-214,Pro,B-34,O,S,O,5-OH-2-Adm,H),(6-215,Pro,B-35,O,S,O,5-OH-2-Adm,H),(6-216,Pro,B-36,O,S,O,5-OH-2-Adm,H),(6-217,Pro,C-1,O,S,O,1-Adm,H),(6-218,Pro,C-2,O,S,O,1-Adm,H),(6-219,Pro,C-3,O,S,O,1-Adm,H),(6-220,Pro,C-4,O,S,O,1-Adm,H),(6-221,Pro,C-5,O,S,O,1-Adm,H),(6-222,Pro,C-6,O,S,O,1-Adm,H),(6-223,Pro,C-7,O,S,O,1-Adm,H),(6-224,Pro,C-8,O,S,O,1-Adm,H),(6-225,Pro,C-9,O,S,O,1-Adm,H),(6-226,Pro,C-1,O,S,O,1-Adm,H),(6-227,Pro,C-11,O,S,O,1-Adm,H),(6-228,Pro,C-12,O,S,O,1-Adm,H),(6-229,Pro,C-13,O,S,O,1-Adm,H),(6-230,Pro,C-14,O,S,O,1-Adm,H),(6-231,Pro,C-15,O,S,O,1-Adm,H),(6-232,Pro,C-16,O,S,O,1-Adm,H),(6-233,Pro,C-17,O,S,O,1-Adm,H),(6-234,Pro,C-18,O,S,O,1-Adm,H),(6-235,Pro,C-19,O,S,O,1-Adm,H),(6-236,Pro,C-20,O,S,O,1-Adm,H),(6-237,Pro,C-21,O,S,O,1-Adm,H),(6-238,Pro,C-22,O,S,O,1-Adm,H),(6-239,Pro,C-23,O,S,O,1-Adm,H),(6-240,Pro,C-24,O,S,O,1-Adm,H),(6-241,Pro,C-25,O,S,O,1-Adm,H),(6-242,Pro,C-26,O,S,O,1-Adm,H),(6-243,Pro,C-27,O,S,O,1-Adm,H),(6-244,Pro,C-28,O,S,O,1-Adm,H),(6-245,Pro,C-29,O,S,O,1-Adm,H),(6-246,Pro,C-30,O,S,O,1-Adm,H),(6-247,Pro,C-31,O,S,O,1-Adm,H),(6-248,Pro,C-32,O,S,O,1-Adm,H),(6-249,Pro,C-33,O,S,O,1-Adm,H),(6-250,Pro,C-34,O,S,O,1-Adm,H),(6-251,Pro,C-35,O,S,O,1-Adm,H),(6-252,Pro,C-36,O,S,O,1-Adm,H),(6-253,Pro,C-1,O,S,O,2-Adm,H),(6-254,Pro,C-2,O,S,O,2-Adm,H),(6-255,Pro,C-3,O,S,O,2-Adm,H),(6-256,Pro,C-4,O,S,O,2-Adm,H),(6-257,Pro,C-5,O,S,O,2-Adm,H),(6-258,Pro,C-6,O,S,O,2-Adm,H),(6-259,Pro,C-7,O,S,O,2-Adm,H),(6-260,Pro,C-8,O,S,O,2-Adm,H),(6-261,Pro,C-9,O,S,O,2-Adm,H),(6-262,Pro,C-10,O,S,O,2-Adm,H),(6-263,Pro,C-11,O,S,O,2-Adm,H),(6-264,Pro,C-12,O,S,O,2-Adm,H),(6-265,Pro,C-13,O,S,O,2-Adm,H),(6-266,Pro,C-14,O,S,O,2-Adm,H),(6-267,Pro,C-15,O,S,O,2-Adm,H),(6-268,Pro,C-16,O,S,O,2-Adm,H),(6-269,Pro,C-17,O,S,O,2-Adm,H),(6-270,Pro,C-18,O,S,O,2-Adm,H),(6-271,Pro,C-19,O,S,O,2-Adm,H),(6-272,Pro,C-20,O,S,O,2-Adm,H),(6-273,Pro,C-21,O,S,O,2-Adm,H),(6-274,Pro,C-22,O,S,O,2-Adm,H),(6-275,Pro,C-23,O,S,O,2-Adm,H),(6-276,Pro,C-24,O,S,O,2-Adm,H),(6-277,Pro,C-25,O,S,O,2-Adm,H),(6-278,Pro,C-26,O,S,O,2-Adm,H),(6-279,Pro,C-27,O,S,O,2-Adm,H),(6-280,Pro,C-28,O,S,O,2-Adm,H),(6-281,Pro,C-29,O,S,O,2-Adm,H),(6-282,Pro,C-30,O,S,O,2-Adm,H),(6-283,Pro,C-31,O,S,O,2-Adm,H),(6-284,Pro,C-32,O,S,O,2-Adm,H),(6-285,Pro,C-33,O,S,O,2-Adm,H),(6-286,Pro,C-34,O,S,O,2-Adm,H),(6-287,Pro,C-35,O,S,O,2-Adm,H),(6-288,Pro,C-36,O,S,O,2-Adm,H),(6-289,Pro,C-1,O,S,O,5-OH-2-Adm,H),(6-290,Pro,C-2,O,S,O,5-OH-2-Adm,H),(6-291,Pro,C-3,O,S,O,5-OH-2-Adm,H),(6-292,Pro,C-4,O,S,O,5-OH-2-Adm,H),(6-293,Pro,C-5,O,S,O,5-OH-2-Adm,H),(6-294,Pro,C-6,O,S,O,5-OH-2-Adm,H),(6-295,Pro,C-7,O,S,O,5-OH-2-Adm,H),(6-296,Pro,C-8,O,S,O,5-OH-2-Adm,H),(6-297,Pro,C-9,O,S,O,5-OH-2-Adm,H),(6-298,Pro,C-10,O,S,O,5-OH-2-Adm,H),(6-299,Pro,C-11,O,S,O,5-OH-2-Adm,H),(6-300,Pro,C-12,O,S,O,5-OH-2-Adm,H),(6-301,Pro,C-13,O,S,O,5-OH-2-Adm,H),(6-302,Pro,C-14,O,S,O,5-OH-2-Adm,H),(6-303,Pro,C-15,O,S,O,5-OH-2-Adm,H),(6-304,Pro,C-16,O,S,O,5-OH-2-Adm,H),(6-305,Pro,C-17,O,S,O,5-OH-2-Adm,H),(6-306,Pro,C-18,O,S,O,5-OH-2-Adm,H),(6-307,Pro,C-19,O,S,O,5-OH-2-Adm,H),(6-308,Pro,C-20,O,S,O,5-OH-2-Adm,H),(6-309,Pro,C-21,O,S,O,5-OH-2-Adm,H),(6-310,Pro,C-22,O,S,O,5-OH-2-Adm,H),(6-311,Pro,C-23,O,S,O,5-OH-2-Adm,H),(6-312,Pro,C-24,O,S,O,5-OH-2-Adm,H),(6-313,Pro,C-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68,Pro,E-36,O,S,O,1-Adm,H),(6-469,Pro,E-1,O,S,O,2-Adm,H),(6-470,Pro,E-2,O,S,O,2-Adm,H),(6-471,Pro,E-3,O,S,O,2-Adm,H),(6-472,Pro,E-4,O,S,O,2-Adm,H),(6-473,Pro,E-5,O,S,O,2-Adm,H),(6-474,Pro,E-6,O,S,O,2-Adm,H),(6-475,Pro,E-7,O,S,O,2-Adm,H),(6-476,Pro,E-8,O,S,O,2-Adm,H),(6-477,Pro,E-9,O,S,O,2-Adm,H),(6-478,Pro,E-10,O,S,O,2-Adm,H),(6-479,Pro,E-11,O,S,O,2-Adm,H),(6-480,Pro,E-12,O,S,O,2-Adm,H),(6-481,Pro,E-13,O,S,O,2-Adm,H),(6-482,Pro,E-14,O,S,O,2-Adm,H),(6-483,Pro,E-15,O,S,O,2-Adm,H),(6-484,Pro,E-16,O,S,O,2-Adm,H),(6-485,Pro,E-17,O,S,O,2-Adm,H),(6-486,Pro,E-18,O,S,O,2-Adm,H),(6-487,Pro,E-19,O,S,O,2-Adm,H),(6-488,Pro,E-20,O,S,O,2-Adm,H),(6-489,Pro,E-21,O,S,O,2-Adm,H),(6-490,Pro,E-22,O,S,O,2-Adm,H),(6-491,Pro,E-23,O,S,O,2-Adm,H),(6-492,Pro,E-24,O,S,O,2-Adm,H),(6-493,Pro,E-25,O,S,O,2-Adm,H),(6-494,Pro,E-26,O,S,O,2-Adm,H),(6-495,Pro,E-27,O,S,O,2-Adm,H),(6-496,Pro,E-28,O,S,O,2-Adm,H),(6-497,Pro,E-29,O,S,O,2-Adm,H),(6-498,Pro,E-30,O,S,O,2-Adm,H),(6-499,Pro,E-31,O,S,O,2-Adm,H),(6-500,Pro,E-32,O,S,O,2-Adm,H),(6-501,Pro,E-33,O,S,O,2-Adm,H),(6-502,Pro,E-34,O,S,O,2-Adm,H),(6-503,Pro,E-35,O,S,O,2-Adm,H),(6-504,Pro,E-36,O,S,O,2-Adm,H),(6-505,Pro,E-1,O,S,O,5-OH-2-Adm,H),(6-506,Pro,E-2,O,S,O,5-OH-2-Adm,H),(6-507,Pro,E-3,O,S,O,5-OH-2-Adm,H),(6-508,Pro,E-4,O,S,O,5-OH-2-Adm,H),(6-509,Pro,E-5,O,S,O,5-OH-2-Adm,H),(6-510,Pro,E-6,O,S,O,5-OH-2-Adm,H),(6-511,Pro,E-7,O,S,O,5-OH-2-Adm,H),(6-512,Pro,E-8,O,S,O,5-OH-2-Adm,H),(6-513,Pro,E-9,O,S,O,5-OH-2-Adm,H),(6-514,Pro,E-10,O,S,O,5-OH-2-Adm,H),(6-515,Pro,E-11,O,S,O,5-OH-2-Adm,H),(6-516,Pro,E-12,O,S,O,5-OH-2-Adm,H),(6-517,Pro,E-13,O,S,O,5-OH-2-Adm,H),(6-518,Pro,E-14,O,S,O,5-OH-2-Adm,H),(6-519,Pro,E-15,O,S,O,5-OH-2-Adm,H),(6-520,Pro,E-16,O,S,O,5-OH-2-Adm,H),(6-521,Pro,E-17,O,S,O,5-OH-2-Adm,H),(6-522,Pro,E-18,O,S,O,5-OH-2-Adm,H),(6-523,Pro,E-19,O,S,O,5-OH-2-Adm,H),(6-524,Pro,E-20,O,S,O,5-OH-2-Adm,H),(6-525,Pro,E-21,O,S,O,5-OH-2-Adm,H),(6-526,Pro,E-22,O,S,O,5-OH-2-Adm,H),(6-527,Pro,E-23,O,S,O,5-OH-2-Adm,H),(6-528,Pro,E-24,O,S,O,5-OH-2-Adm,H),(6-529,Pro,E-25,O,S,O,5-OH-2-Adm,H),(6-530,Pro,E-26,O,S,O,5-OH-2-Adm,H),(6-531,Pro,E-27,O,S,O,5-OH-2-Adm,H),(6-532,Pro,E-28,O,S,O,5-OH-2-Adm,H),(6-533,Pro,E-29,O,S,O,5-OH-2-Adm,H),(6-534,Pro,E-30,O,S,O,5-OH-2-Adm,H),(6-535,Pro,E-31,O,S,O,5-OH-2-Adm,H),(6-536,Pro,E-32,O,S,O,5-OH-2-Adm,H),(6-537,Pro,E-33,O,S,O,5-OH-2-Adm,H),(6-538,Pro,E-34,O,S,O,5-OH-2-Adm,H),(6-539,Pro,E-35,O,S,O,5-OH-2-Adm,H),(6-540,Pro,E-36,O,S,O,5-OH-2-Adm,H),(6-541,Pro,F-1,O,S,O,1-Adm,H),(6-542,Pro,F-2,O,S,O,1-Adm,H),(6-543,Pro,F-3,O,S,O,1-Adm,H),(6-544,Pro,F-4,O,S,O,1-Adm,H),(6-545,Pro,F-5,O,S,O,1-Adm,H),(6-546,Pro,F-6,O,S,O,1-Adm,H),(6-547,Pro,F-7,O,S,O,1-Adm,H),(6-548,Pro,F-8,O,S,O,1-Adm,H),(6-549,Pro,F-9,O,S,O,1-Adm,H),(6-550,Pro,F-10,O,S,O,1-Adm,H),(6-551,Pro,F-11,O,S,O,1-Adm,H),(6-552,Pro,F-12,O,S,O,1-Adm,H),(6-553,Pro,F-13,O,S,O,1-Adm,H),(6-554,Pro,F-14,O,S,O,1-Adm,H),(6-555,Pro,F-15,O,S,O,1-Adm,H),(6-556,Pro,F-16,O,S,O,1-Adm,H),(6-557,Pro,F-17,O,S,O,1-Adm,H),(6-558,Pro,F-18,O,S,O,1-Adm,H),(6-559,Pro,F-19,O,S,O,1-Adm,H),(6-560,Pro,F-20,O,S,O,1-Adm,H),(6-561,Pro,F-21,O,S,O,1-Adm,H),(6-562,Pro,F-22,O,S,O,1-Adm,H),(6-563,Pro,F-23,O,S,O,1-Adm,H),(6-564,Pro,F-24,O,S,O,1-Adm,H),(6-565,Pro,F-25,O,S,O,1-Adm,H),(6-566,Pro,F-26,O,S,O,1-Adm,H),(6-567,Pro,F-27,O,S,O,1-Adm,H),(6-568,Pro,F-28,O,S,O,1-Adm,H),(6-569,Pro,F-29,O,S,O,1-Adm,H),(6-570,Pro,F-30,O,S,O,1-Adm,H),(6-571,Pro,F-31,O,S,O,1-Adm,H),(6-572,Pro,F-32,O,S,O,1-Adm,H),(6-573,Pro,F-33,O,S,O,1-Adm,H),(6-574,Pro,F-34,O,S,O,1-Adm,H),(6-575,Pro,F-35,O,S,O,1-Adm,H),(6-576,Pro,F-36,O,S,O,1-Adm,H),(6-577,Pro,F-1,O,S,O,2-Adm,H),(6-578,Pro,F-2,O,S,O,2-Adm,H),(6-579,Pro,F-3,O,S,O,2-Adm,H),(6-580,Pro,F-4,O,S,O,2-Adm,H),(6-581,Pro,F-5,O,S,O,2-Adm,H),(6-582,Pro,F-6,O,S,O,2-Adm,H),(6-583,Pro,F-7,O,S,O,2-Adm,H),(6-584,Pro,F-8,O,S,O,2-Adm,H),(6-585,Pro,F-9,O,S,O,2-Adm,H),(6-586,Pro,F-10,O,S,O,2-Adm,H),(6-587,Pro,F-11,O,S,O,2-Adm,H),(6-588,Pro,F-12,O,S,O,2-Adm,H),(6-589,Pro,F-13,O,S,O,2-Adm,H),(6-590,Pro,F-14,O,S,O,2-Adm,H),(6-591,Pro,F-15,O,S,O,2-Adm,H),(6-592,Pro,F-16,O,S,O,2-Adm,H),(6-593,Pro,F-17,O,S,O,2-Adm,H),(6-594,Pro,F-18,O,S,O,2-Adm,H),(6-595,Pro,F-19,O,S,O,2-Adm,H),(6-596,Pro,F-20,O,S,O,2-Adm,H),(6-597,Pro,F-21,O,S,O,2-Adm,H),(6-598,Pro,F-22,O,S,O,2-Adm,H),(6-599,Pro,F-23,O,S,O,2-Adm,H),(6-600,Pro,F-24,O,S,O,2-Adm,H),(6-601,Pro,F-25,O,S,O,2-Adm,H),(6-602,Pro,F-26,O,S,O,2-Adm,H),(6-603,Pro,F-27,O,S,O,2-Adm,H),(6-604,Pro,F-28,O,S,O,2-Adm,H),(6-605,Pro,F-29,O,S,O,2-Adm,H),(6-606,Pro,F-30,O,S,O,2-Adm,H),(6-607,Pro,F-31,O,S,O,2-Adm,H),(6-608,Pro,F-32,O,S,O,2-Adm,H),(6-609,Pro,F-33,O,S,O,2-Adm,H),(6-610,Pro,F-34,O,S,O,2-Adm,H),(6-611,Pro,F-35,O,S,O,2-Adm,H),(6-612,Pro,F-36,O,S,O,2-Adm,H),(6-613,Pro,F-1,O,S,O,5-OH-2-Adm,H),(6-614,Pro,F-2,O,S,O,5-OH-2-Adm,H),(6-615,Pro,F-3,O,S,O,5-OH-2-Adm,H),(6-616,Pro,F-4,O,S,O,5-OH-2-Adm,H),(6-617,Pro,F-5,O,S,O,5-OH-2-Adm,H),(6-618,Pro,F-6,O,S,O,5-OH-2-Adm,H),(6-619,Pro,F-7,O,S,O,5-OH-2-Adm,H),(6-620,Pro,F-8,O,S,O,5-OH-2-Adm,H),(6-621,Pro,F-9,O,S,O,5-OH-2-Adm,H),(6-622,Pro,F-10,O,S,O,5-OH-2-Adm,H),(6-623,Pro,F-11,O,S,O,5-OH-2-Adm,H),(6-624,Pro,F-12,O,S,O,5-OH-2-Adm,H),(6-625,Pro,F-13,O,S,O,5-OH-2-Adm,H),(6-626,Pro,F-14,O,S,O,5-OH-2-Adm,H),(6-627,Pro,F-15,O,S,O,5-OH-2-Adm,H),(6-628,Pro,F-16,O,S,O,5-OH-2-Adm,H),(6-629,Pro,F-17,O,S,O,5-OH-2-Adm,H),(6-630,Pro,F-18,O,S,O,5-OH-2-Adm,H),(6-631,Pro,F-19,O,S,O,5-OH-2-Adm,H),(6-632,Pro,F-20,O,S,O,5-OH-2-Adm,H),(6-633,Pro,F-21,O,S,O,5-OH-2-Adm,H),(6-634,Pro,F-22,O,S,O,5-OH-2-Adm,H),(6-635,Pro,F-23,O,S,O,5-OH-2-Adm,H),(6-636,Pro,F-24,O,S,O,5-OH-2-Adm,H),(6-637,Pro,F-25,O,S,O,5-OH-2-Adm,H),(6-638,Pro,F-26,O,S,O,5-OH-2-Adm,H),(6-639,Pro,F-27,O,S,O,5-OH-2-Adm,H),(6-640,Pro,F-28,O,S,O,5-OH-2-Adm,H),(6-641,Pro,F-29,O,S,O,5-OH-2-Adm,H),(6-642,Pro,F-30,O,S,O,5-OH-2-Adm,H),(6-643,Pro,F-31,O,S,O,5-OH-2-Adm,H),(6-644,Pro,F-32,O,S,O,5-OH-2-Adm,H),(6-645,Pro,F-33,O,S,O,5-OH-2-Adm,H),(6-646,Pro,F-34,O,S,O,5-OH-2-Adm,H),(6-647,Pro,F-35,O,S,O,5-OH-2-Adm,H),(6-648,Pro,F-36,O,S,O,5-OH-2-Adm,H),(6-649,Pro,G-1,O,S,O,1-Adm,H),(6-650,Pro,G-2,O,S,O,1-Adm,H),(6-651,Pro,G-3,O,S,O,1-Adm,H),(6-652,Pro,G-4,O,S,O,1-Adm,H),(6-653,Pro,G-5,O,S,O,1-Adm,H),(6-654,Pro,G-6,O,S,O,1-Adm,H),(6-655,Pro,G-7,O,S,O,1-Adm,H),(6-656,Pro,G-8,O,S,O,1-Adm,H),(6-657,Pro,G-9,O,S,O,1-Adm,H),(6-658,Pro,G-1,O,S,O,2-Adm,H),(6-659,Pro,G-2,O,S,O,2-Adm,H),(6-660,Pro,G-3,O,S,O,2-Adm,H),(6-661,Pro,G-4,O,S,O,2-Adm,H),(6-662,Pro,G-5,O,S,O,2-Adm,H),(6-663,Pro,G-6,O,S,O,2-Adm,H),(6-664,Pro,G-7,O,S,O,2-Adm,H),(6-665,Pro,G-8,O,S,O,2-Adm,H),(6-666,Pro,G-9,O,S,O,2-Adm,H),(6-667,Pro,G-1,O,S,O,5-OH-2-Adm,H),(6-668,Pro,G-2,O,S,O,5-OH-2-Adm,H),(6-669,Pro,G-3,O,S,O,5-OH-2-Adm,H),(6-670,Pro,G-4,O,S,O,5-OH-2-Adm,H),(6-671,Pro,G-5,O,S,O,5-OH-2-Adm,H),(6-672,Pro,G-6,O,S,O,5-OH-2-Adm,H),(6-673,Pro,G-7,O,S,O,5-OH-2-Adm,H),(6-674,Pro,G-8,O,S,O,5-OH-2-Adm,H),(6-675,Pro,G-9,O,S,O,5-OH-2-Adm,H),(6-676,Pro,H-1,O,S,O,1-Adm,H),(6-677,Pro,H-2,O,S,O,1-Adm,H),(6-678,Pro,H-3,O,S,O,1-Adm,H),(6-679,Pro,H-4,O,S,O,1-Adm,H),(6-680,Pro,H-5,O,S,O,1-Adm,H),(6-681,Pro,H-6,O,S,O,1-Adm,H),(6-682,Pro,H-7,O,S,O,1-Adm,H),(6-683,Pro,H-8,O,S,O,1-Adm,H),(6-684,Pro,H-9,O,S,O,1-Adm,H),(6-685,Pro,H-1,O,S,O,2-Adm,H),(6-686,Pro,H-2,O,S,O,2-Adm,H),(6-687,Pro,H-3,O,S,O,2-Adm,H),(6-688,Pro,H-4,O,S,O,2-Adm,H),(6-689,Pro,H-5,O,S,O,2-Adm,H),(6-690,Pro,H-6,O,S,O,2-Adm,H),(6-691,Pro,H-7,O,S,O,2-Adm,H),(6-692,Pro,H-8,O,S,O,2-Adm,H),(6-693,Pro,H-9,O,S,O,2-Adm,H),(6-694,Pro,H-1,O,S,O,5-OH-2-Adm,H),(6-695,Pro,H-2,O,S,O,5-OH-2-Adm,H),(6-696,Pro,H-3,O,S,O,5-OH-2-Adm,H),(6-697,Pro,H-4,O,S,O,5-OH-2-Adm,H),(6-698,Pro,H-5,O,S,O,5-OH-2-Adm,H),(6-699,Pro,H-6,O,S,O,5-OH-2-Adm,H),(6-700,Pro,H-7,O,S,O,5-OH-2-Adm,H),(6-701,Pro,H-8,O,S,O,5-OH-2-Adm,H),(6-702,Pro,H-9,O,S,O,5-OH-2-Adm,H),(6-703,Pro,I-1,O,S,O,1-Adm,H),(6-704,Pro,I-2,O,S,O,1-Adm,H),(6-705,Pro,I-3,O,S,O,1-Adm,H),(6-706,Pro,I-4,O,S,O,1-Adm,H),(6-707,Pro,I-5,O,S,O,1-Adm,H),(6-708,Pro,I-6,O,S,O,1-Adm,H),(6-709,Pro,I-7,O,S,O,1-Adm,H),(6-710,Pro,I-8,O,S,O,1-Adm,H),(6-711,Pro,I-9,O,S,O,1-Adm,H),(6-712,Pro,I-1,O,S,O,2-Adm,H),(6-713,Pro,I-2,O,S,O,2-Adm,H),(6-714,Pro,I-3,O,S,O,2-Adm,H),(6-715,Pro,I-4,O,S,O,2-Adm,H),(6-716,Pro,I-5,O,S,O,2-Adm,H),(6-717,Pro,I-6,O,S,O,2-Adm,H),(6-718,Pro,I-7,O,S,O,2-Adm,H),(6-719,Pro,I-8,O,S,O,2-Adm,H),(6-720,Pro,I-9,O,S,O,2-Adm,H),(6-721,Pro,I-1,O,S,O,5-OH-2-Adm,H),(6-722,Pro,I-2,O,S,O,5-OH-2-Adm,H),(6-723,Pro,I-3,O,S,O,5-OH-2-Adm,H),(6-724,Pro,I-4,O,S,O,5-OH-2-Adm,H),(6-725,Pro,I-5,O,S,O,5-OH-2-Adm,H),(6-726,Pro,I-6,O,S,O,5-OH-2-Adm,H),(6-727,Pro,I-7,O,S,O,5-OH-2-Adm,H),(6-728,Pro,I-8,O,S,O,5-OH-2-Adm,H),(6-729,Pro,I-9,O,S,O,5-OH-2-Adm,H),(6-730,Pro,J-1,O,S,O,1-Adm,H),(6-731,Pro,J-2,O,S,O,1-Adm,H),(6-732,Pro,J-3,O,S,O,1-Adm,H),(6-733,Pro,J-4,O,S,O,1-Adm,H),(6-734,Pro,J-5,O,S,O,1-Adm,H),(6-735,Pro,J-6,O,S,O,1-Adm,H),(6-736,Pro,J-7,O,S,O,1-Adm,H),(6-737,Pro,J-8,O,S,O,1-Adm,H),(6-738,Pro,J-9,O,S,O,1-Adm,H),(6-739,Pro,J-1,O,S,O,2-Adm,H),(6-740,Pro,J-2,O,S,O,2-Adm,H),(6-741,Pro,J-3,O,S,O,2-Adm,H),(6-742,Pro,J-4,O,S,O,2-Adm,H),(6-743,Pro,J-5,O,S,O,2-Adm,H),(6-744,Pro,J-6,O,S,O,2-Adm,H),(6-745,Pro,J-7,O,S,O,2-Adm,H),(6-746,Pro,J-8,O,S,O,2-Adm,H),(6-747,Pro,J-9,O,S,O,2-Adm,H),(6-748,Pro,J-1,O,S,O,5-OH-2-Adm,H),(6-749,Pro,J-2,O,S,O,5-OH-2-Adm,H),(6-750,Pro,J-3,O,S,O,5-OH-2-Adm,H),(6-751,Pro,J-4,O,S,O,5-OH-2-Adm,H),(6-752,Pro,J-5,O,S,O,5-OH-2-Adm,H),(6-753,Pro,J-6,O,S,O,5-OH-2-Adm,H),(6-754,Pro,J-7,O,S,O,5-OH-2-Adm,H),(6-755,Pro,J-8,O,S,O,5-OH-2-Adm,H),(6-756,Pro,J-9,O,S,O,5-OH-2-Adm,H),(6-757,Pro,K-1,O,S,O,1-Adm,H),(6-758,Pro,K-2,O,S,O,1-Adm,H),(6-759,Pro,K-3,O,S,O,1-Adm,H),(6-760,Pro,K-4,O,S,O,1-Adm,H),(6-761,Pro,K-5,O,S,O,1-Adm,H),(6-762,Pro,K-6,O,S,O,1-Adm,H),(6-763,Pro,K-7,O,S,O,1-Adm,H),(6-764,Pro,K-8,O,S,O,1-Adm,H),(6-765,Pro,K-9,O,S,O,1-Adm,H),(6-766,Pro,K-1,O,S,O,2-Adm,H),(6-767,Pro,K-2,O,S,O,2-Adm,H),(6-768,Pro,K-3,O,S,O,2-Adm,H),(6-769,Pro,K-4,O,S,O,2-Adm,H),(6-770,Pro,K-5,O,S,O,2-Adm,H),(6-771,Pro,K-6,O,S,O,2-Adm,H),(6-772,Pro,K-7,O,S,O,2-Adm,H),(6-773,Pro,K-8,O,S,O,2-Adm,H),(6-774,Pro,K-9,O,S,O,2-Adm,H),(6-775,Pro,K-1,O,S,O,5-OH-2-Adm,H),(6-776,Pro,K-2,O,S,O,5-OH-2-Adm,H),(6-777,Pro,K-3,O,S,O,5-OH-2-Adm,H),(6-778,Pro,K-4,O,S,O,5-OH-2-Adm,H),(6-779,Pro,K-5,O,S,O,5-OH-2-Adm,H),(6-780,Pro,K-6,O,S,O,5-OH-2-Adm,H),(6-781,Pro,K-7,O,S,O,5-OH-2-Adm,H),(6-782,Pro,K-8,O,S,O,5-OH-2-Adm,H),(6-783,Pro,K-9,O,S,O,5-OH-2-Adm,H)

Concretely, the defined compound is shown by using the formula (VI).

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(7-1,i-Bu,A-1,S,S,O,1-Adm,H),(7-2,i-Bu,A-2,S,S,O,1-Adm,H),(7-3,i-Bu,A-3,S,S,O,1-Adm,H),(7-4,i-Bu,A-4,S,S,O,1-Adm,H),(7-5,i-Bu,A-5,S,S,O,1-Adm,H),(7-6,i-Bu,A-6,S,S,O,1-Adm,H),(7-7,i-Bu,A-7,S,S,O,1-Adm,H),(7-8,i-Bu,A-8,S,S,O,1-Adm,H),(7-9,i-Bu,A-9,S,S,O,1-Adm,H),(7-10,i-Bu,A-10,S,S,O,1-Adm,H),(7-11,i-Bu,A-11,S,S,O,1-Adm,H),(7-12,i-Bu,A-12,S,S,O,1-Adm,H),(7-13,i-Bu,A-13,S,S,O,1-Adm,H),(7-14,i-Bu,A-14,S,S,O,1-Adm,H),(7-15,i-Bu,A-15,S,S,O,1-Adm,H),(7-16,i-Bu,A-16,S,S,O,1-Adm,H),(7-17,i-Bu,A-17,S,S,O,1-Adm,H),(7-18,i-Bu,A-18,S,S,O,1-Adm,H),(7-19,i-Bu,A-19,S,S,O,1-Adm,H),(7-20,i-Bu,A-20,S,S,O,1-Adm,H),(7-21,i-Bu,A-21,S,S,O,1-Adm,H),(7-22,i-Bu,A-22,S,S,O,1-Adm,H),(7-23,i-Bu,A-23,S,S,O,1-Adm,H),(7-24,i-Bu,A-24,S,S,O,1-Adm,H),(7-25,i-Bu,A-25,S,S,O,1-Adm,H),(7-26,i-Bu,A-26,S,S,O,1-Adm,H),(7-27,i-Bu,A-27,S,S,O,1-Adm,H),(7-28,i-Bu,A-28,S,S,O,1-Adm,H),(7-29,i-Bu,A-29,S,S,O,1-Adm,H),(7-30,i-Bu,A-30,S,S,O,1-Adm,H),(7-31,i-Bu,A-31,S,S,O,1-Adm,H),(7-32,i-Bu,A-32,S,S,O,1-Adm,H),(7-33,i-Bu,A-33,S,S,O,1-Adm,H),(7-34,i-Bu,A-34,S,S,O,1-Adm,H),(7-35,i-Bu,A-35,S,S,O,1-Adm,H),(7-36,i-Bu,A-36,S,S,O,1-Adm,H),(7-37,i-Bu,A-1,S,S,O,2-Adm,H),(7-38,i-Bu,A-2,S,S,O,2-Adm,H),(7-39,i-Bu,A-3,S,S,O,2-Adm,H),(7-40,i-Bu,A-4,S,S,O,2-Adm,H),(7-41,i-Bu,A-5,S,S,O,2-Adm,H),(7-42,i-Bu,A-6,S,S,O,2-Adm,H),(7-43,i-Bu,A-7,S,S,O,2-Adm,H),(7-44,i-Bu,A-8,S,S,O,2-Adm,H),(7-45,i-Bu,A-9,S,S,O,2-Adm,H),(7-46,i-Bu,A-10,S,S,O,2-Adm,H),(7-47,i-Bu,A-11,S,S,O,2-Adm,H),(7-48,i-Bu,A-12,S,S,O,2-Adm,H),(7-49,i-Bu,A-13,S,S,O,2-Adm,H),(7-50,i-Bu,A-14,S,S,O,2-Adm,H),(7-51,i-Bu,A-15,S,S,O,2-Adm,H),(7-52,i-Bu,A-16,S,S,O,2-Adm,H),(7-53,i-Bu,A-17,S,S,O,2-Adm,H),(7-54,i-Bu,A-18,S,S,O,2-Adm,H),(7-55,i-Bu,A-19,S,S,O,2-Adm,H),(7-56,i-Bu,A-20,S,S,O,2-Adm,H),(7-57,i-Bu,A-21,S,S,O,2-Adm,H),(7-58,i-Bu,A-22,S,S,O,2-Adm,H),(7-59,i-Bu,A-23,S,S,O,2-Adm,H),(7-60,i-Bu,A-24,S,S,O,2-Adm,H),(7-61,i-Bu,A-25,S,S,O,2-Adm,H),(7-62,i-Bu,A-26,S,S,O,2-Adm,H),(7-63,i-Bu,A-27,S,S,O,2-Adm,H),(7-64,i-Bu,A-28,S,S,O,2-Adm,H),(7-65,i-Bu,A-29,S,S,O,2-Adm,H),(7-66,i-Bu,A-30,S,S,O,2-Adm,H),(7-67,i-Bu,A-31,S,S,O,2-Adm,H),(7-68,i-Bu,A-32,S,S,O,2-Adm,H),(7-69,i-Bu,A-33,S,S,O,2-Adm,H),(7-70,i-Bu,A-34,S,S,O,2-Adm,H),(7-71,i-Bu,A-35,S,S,O,2-Adm,H),(7-72,i-Bu,A-36,S,S,O,2-Adm,H),(7-73,i-Bu,A-1,S,S,O,5-OH-2-Adm,H),(7-74,i-Bu,A-2,S,S,O,5-OH-2-Adm,H),(7-75,i-Bu,A-3,S,S,O,5-OH-2-Adm,H),(7-76,i-Bu,A-4,S,S,O,5-OH-2-Adm,H),(7-77,i-Bu,A-5,S,S,O,5-OH-2-Adm,H),(7-78,i-Bu,A-6,S,S,O,5-OH-2-Adm,H),(7-79,i-Bu,A-7,S,S,O,5-OH-2-Adm,H),(7-80,i-Bu,A-8,S,S,O,5-OH-2-Adm,H),(7-81,i-Bu,A-9,S,S,O,5-OH-2-Adm,H),(7-82,i-Bu,A-10,S,S,O,5-OH-2-Adm,H),(7-83,i-Bu,A-11,S,S,O,5-OH-2-Adm,H),(7-84,i-Bu,A-12,S,S,O,5-OH-2-Adm,H),(7-85,i-Bu,A-13,S,S,O,5-OH-2-Adm,H),(7-86,i-Bu,A-14,S,S,O,5-OH-2-Adm,H),(7-87,i-Bu,A-15,S,S,O,5-OH-2-Adm,H),(7-88,i-Bu,A-16,S,S,O,5-OH-2-Adm,H),(7-89,i-Bu,A-17,S,S,O,5-OH-2-Adm,H),(7-90,i-Bu,A-18,S,S,O,5-OH-2-Adm,H),(7-91,i-Bu,A-19,S,S,O,5-OH-2-Adm,H),(7-92,i-Bu,A-20,S,S,O,5-OH-2-Adm,H),(7-93,i-Bu,A-21,S,S,O,5-OH-2-Adm,H),(7-94,i-Bu,A-22,S,S,O,5-OH-2-Adm,H),(7-95,i-Bu,A-23,S,S,O,5-OH-2-Adm,H),(7-96,i-Bu,A-24,S,S,O,5-OH-2-Adm,H),(7-97,i-Bu,A-25,S,S,O,5-OH-2-Adm,H),(7-98,i-Bu,A-26,S,S,O,5-OH-2-Adm,H),(7-99,i-Bu,A-27,S,S,O,5-OH-2-Adm,H),(7-100,i-Bu,A-28,S,S,O,5-OH-2-Adm,H),(7-101,i-Bu,A-29,S,S,O,5-OH-2-Adm,H),(7-102,i-Bu,A-30,S,S,O,5-OH-2-Adm,H),(7-103,i-Bu,A-31,S,S,O,5-OH-2-Adm,H),(7-104,i-Bu,A-32,S,S,O,5-OH-2-Adm,H),(7-105,i-Bu,A-33,S,S,O,5-OH-2-Adm,H),(7-106,i-Bu,A-34,S,S,O,5-OH-2-Adm,H),(7-107,i-Bu,A-35,S,S,O,5-OH-2-Adm,H),(7-108,i-Bu,A-36,S,S,O,5-OH-2-Adm,H),(7-109,i-Bu,B-1,S,S,O,1-Adm,H),(7-110,i-Bu,B-2,S,S,O,1-Adm,H),(7-111,i-Bu,B-3,S,S,O,1-Adm,H),(7-112,i-Bu,B-4,S,S,O,1-Adm,H),(7-113,i-Bu,B-5,S,S,O,1-Adm,H),(7-114,i-Bu,B-6,S,S,O,1-Adm,H),(7-115,i-Bu,B-7,S,S,O,1-Adm,H),(7-116,i-Bu,B-8,S,S,O,1-Adm,H),(7-117,i-Bu,B-9,S,S,O,1-Adm,H),(7-118,i-Bu,B-10,S,S,O,1-Adm,H),(7-119,i-Bu,B-11,S,S,O,1-Adm,H),(7-120,i-Bu,B-12,S,S,O,1-Adm,H),(7-121,i-Bu,B-13,S,S,O,1-Adm,H),(7-122,i-Bu,B-14,S,S,O,1-Adm,H),(7-123,i-Bu,B-15,S,S,O,1-Adm,H),(7-124,i-Bu,B-16,S,S,O,1-Adm,H),(7-125,i-Bu,B-17,S,S,O,1-Adm,H),(7-126,i-Bu,B-18,S,S,O,1-Adm,H),(7-127,i-Bu,B-19,S,S,O,1-Adm,H),(7-128,i-Bu,B-20,S,S,O,1-Adm,H),(7-129,i-Bu,B-21,S,S,O,1-Adm,H),(7-130,i-Bu,B-22,S,S,O,1-Adm,H),(7-131,i-Bu,B-23,S,S,O,1-Adm,H),(7-132,i-Bu,B-24,S,S,O,1-Adm,H),(7-133,i-Bu,B-25,S,S,O,1-Adm,H),(7-134,i-Bu,B-26,S,S,O,1-Adm,H),(7-135,i-Bu,B-27,S,S,O,1-Adm,H),(7-136,i-Bu,B-28,S,S,O,1-Adm,H),(7-137,i-Bu,B-29,S,S,O,1-Adm,H),(7-138,i-Bu,B-30,S,S,O,1-Adm,H),(7-139,i-Bu,B-31,S,S,O,1-Adm,H),(7-140,i-Bu,B-32,S,S,O,1-Adm,H),(7-141,i-Bu,B-33,S,S,O,1-Adm,H),(7-142,i-Bu,B-34,S,S,O,1-Adm,H),(7-143,i-Bu,B-35,S,S,O,1-Adm,H),(7-144,i-Bu,B-36,S,S,O,1-Adm,H),(7-145,i-Bu,B-1,S,S,O,2-Adm,H),(7-146,i-Bu,B-2,S,S,O,2-Adm,H),(7-147,i-Bu,B-3,S,S,O,2-Adm,H),(7-148,i-Bu,B-4,S,S,O,2-Adm,H),(7-149,i-Bu,B-5,S,S,O,2-Adm,H),(7-150,i-Bu,B-6,S,S,O,2-Adm,H),(7-151,i-Bu,B-7,S,S,O,2-Adm,H),(7-152,i-Bu,B-8,S,S,O,2-Adm,H),(7-153,i-Bu,B-9,S,S,O,2-Adm,H),(7-154,i-Bu,B-10,S,S,O,2-Adm,H),(7-155,i-Bu,B-11,S,S,O,2-Adm,H),(7-156,i-Bu,B-12,S,S,O,2-Adm,H),(7-157,i-Bu,B-13,S,S,O,2-Adm,H),(7-158,i-Bu,B-14,S,S,O,2-Adm,H),(7-159,i-Bu,B-15,S,S,O,2-Adm,H),(7-160,i-Bu,B-16,S,S,O,2-Adm,H),(7-161,i-Bu,B-17,S,S,O,2-Adm,H),(7-162,i-Bu,B-18,S,S,O,2-Adm,H),(7-163,i-Bu,B-19,S,S,O,2-Adm,H),(7-164,i-Bu,B-20,S,S,O,2-Adm,H),(7-165,i-Bu,B-21,S,S,O,2-Adm,H),(7-166,i-Bu,B-22,S,S,O,2-Adm,H),(7-167,i-Bu,B-23,S,S,O,2-Adm,H),(7-168,i-Bu,B-24,S,S,O,2-Adm,H),(7-169,i-Bu,B-25,S,S,O,2-Adm,H),(7-170,i-Bu,B-26,S,S,O,2-Adm,H),(7-171,i-Bu,B-27,S,S,O,2-Adm,H),(7-172,i-Bu,B-28,S,S,O,2-Adm,H),(7-173,i-Bu,B-29,S,S,O,2-Adm,H),(7-174,i-Bu,B-30,S,S,O,2-Adm,H),(7-175,i-Bu,B-31,S,S,O,2-Adm,H),(7-176,i-Bu,B-32,S,S,O,2-Adm,H),(7-177,i-Bu,B-33,S,S,O,2-Adm,H),(7-178,i-Bu,B-34,S,S,O,2-Adm,H),(7-179,i-Bu,B-35,S,S,O,2-Adm,H),(7-180,i-Bu,B-36,S,S,O,2-Adm,H),(7-181,i-Bu,B-1,S,S,O,5-OH-2-Adm,H),(7-182,i-Bu,B-2,S,S,O,5-OH-2-Adm,H),(7-183,i-Bu,B-3,S,S,O,5-OH-2-Adm,H),(7-184,i-Bu,B-4,S,S,O,5-OH-2-Adm,H),(7-185,i-Bu,B-5,S,S,O,5-OH-2-Adm,H),(7-186,i-Bu,B-6,S,S,O,5-OH-2-Adm,H),(7-187,i-Bu,B-7,S,S,O,5-OH-2-Adm,H),(7-188,i-Bu,B-8,S,S,O,5-OH-2-Adm,H),(7-189,i-Bu,B-9,S,S,O,5-OH-2-Adm,H),(7-190,i-Bu,B-10,S,S,O,5-OH-2-Adm,H),(7-191,i-Bu,B-11,S,S,O,5-OH-2-Adm,H),(7-192,i-Bu,B-12,S,S,O,5-OH-2-Adm,H),(7-193,i-Bu,B-13,S,S,O,5-OH-2-Adm,H),(7-194,i-Bu,B-14,S,S,O,5-OH-2-Adm,H),(7-195,i-Bu,B-15,S,S,O,5-OH-2-Adm,H),(7-196,i-Bu,B-16,S,S,O,5-OH-2-Adm,H),(7-197,i-Bu,B-17,S,S,O,5-OH-2-Adm,H),(7-198,i-Bu,B-18,S,S,O,5-OH-2-Adm,H),(7-199,i-Bu,B-19,S,S,O,5-OH-2-Adm,H),(7-200,i-Bu,B-20,S,S,O,5-OH-2-Adm,H),(7-201,i-Bu,B-21,S,S,O,5-OH-2-Adm,H),(7-202,i-Bu,B-22,S,S,O,5-OH-2-Adm,H),(7-203,i-Bu,B-23,S,S,O,5-OH-2-Adm,H),(7-204,i-Bu,B-24,S,S,O,5-OH-2-Adm,H),(7-205,i-Bu,B-25,S,S,O,5-OH-2-Adm,H),(7-206,i-Bu,B-26,S,S,O,5-OH-2-Adm,H),(7-207,i-Bu,B-27,S,S,O,5-OH-2-Adm,H),(7-208,i-Bu,B-28,S,S,O,5-OH-2-Adm,H),(7-209,i-Bu,B-29,S,S,O,5-OH-2-Adm,H),(7-210,i-Bu,B-30,S,S,O,5-OH-2-Adm,H),(7-211,i-Bu,B-31,S,S,O,5-OH-2-Adm,H),(7-212,i-Bu,B-32,S,S,O,5-OH-2-Adm,H),(7-213,i-Bu,B-33,S,S,O,5-OH-2-Adm,H),(7-214,i-Bu,B-34,S,S,O,5-OH-2-Adm,H),(7-215,i-Bu,B-35,S,S,O,5-OH-2-Adm,H),(7-216,i-Bu,B-36,S,S,O,5-OH-2-Adm,H),(7-217,i-Bu,C-1,S,S,O,1-Adm,H),(7-218,i-Bu,C-2,S,S,O,1-Adm,H),(7-219,i-Bu,C-3,S,S,O,1-Adm,H),(7-220,i-Bu,C-4,S,S,O,1-Adm,H),(7-221,i-Bu,C-5,S,S,O,1-Adm,H),(7-222,i-Bu,C-6,S,S,O,1-Adm,H),(7-223,i-Bu,C-7,S,S,O,1-Adm,H),(7-224,i-Bu,C-8,S,S,O,1-Adm,H),(7-225,i-Bu,C-9,S,S,O,1-Adm,H),(7-226,i-Bu,C-10,S,S,O,1-Adm,H),(7-227,i-Bu,C-11,S,S,O,1-Adm,H),(7-228,i-Bu,C-12,S,S,O,1-Adm,H),(7-229,i-Bu,C-13,S,S,O,1-Adm,H),(7-230,i-Bu,C-14,S,S,O,1-Adm,H),(7-231,i-Bu,C-15,S,S,O,1-Adm,H),(7-232,i-Bu,C-16,S,S,O,1-Adm,H),(7-233,i-Bu,C-17,S,S,O,1-Adm,H),(7-234,i-Bu,C-18,S,S,O,1-Adm,H),(7-235,i-Bu,C-19,S,S,O,1-Adm,H),(7-236,i-Bu,C-20,S,S,O,1-Adm,H),(7-237,i-Bu,C-21,S,S,O,1-Adm,H),(7-238,i-Bu,C-22,S,S,O,1-Adm,H),(7-239,i-Bu,C-23,S,S,O,1-Adm,H),(7-240,i-Bu,C-24,S,S,O,1-Adm,H),(7-241,i-Bu,C-25,S,S,O,1-Adm,H),(7-242,i-Bu,C-26,S,S,O,1-Adm,H),(7-243,i-Bu,C-27,S,S,O,1-Adm,H),(7-244,i-Bu,C-28,S,S,O,1-Adm,H),(7-245,i-Bu,C-29,S,S,O,1-Adm,H),(7-246,i-Bu,C-30,S,S,O,1-Adm,H),(7-247,i-Bu,C-31,S,S,O,1-Adm,H),(7-248,i-Bu,C-32,S,S,O,1-Adm,H),(7-249,i-Bu,C-33,S,S,O,1-Adm,H),(7-250,i-Bu,C-34,S,S,O,1-Adm,H),(7-251,i-Bu,C-35,S,S,O,1-Adm,H),(7-252,i-Bu,C-36,S,S,O,1-Adm,H),(7-253,i-Bu,C-1,S,S,O,2-Adm,H),(7-254,i-Bu,C-2,S,S,O,2-Adm,H),(7-255,i-Bu,C-3,S,S,O,2-Adm,H),(7-256,i-Bu,C-4,S,S,O,2-Adm,H),(7-257,i-Bu,C-5,S,S,O,2-Adm,H),(7-258,i-Bu,C-6,S,S,O,2-Adm,H),(7-259,i-Bu,C-7,S,S,O,2-Adm,H),(7-260,i-Bu,C-8,S,S,O,2-Adm,H),(7-261,i-Bu,C-9,S,S,O,2-Adm,H),(7-262,i-Bu,C-10,S,S,O,2-Adm,H),(7-263,i-Bu,C-11,S,S,O,2-Adm,H),(7-264,i-Bu,C-12,S,S,O,2-Adm,H),(7-265,i-Bu,C-13,S,S,O,2-Adm,H),(7-266,i-Bu,C-14,S,S,O,2-Adm,H),(7-267,i-Bu,C-15,S,S,O,2-Adm,H),(7-268,i-Bu,C-16,S,S,O,2-Adm,H),(7-269,i-Bu,C-17,S,S,O,2-Adm,H),(7-270,i-Bu,C-18,S,S,O,2-Adm,H),(7-271,i-Bu,C-19,S,S,O,2-Adm,H),(7-272,i-Bu,C-20,S,S,O,2-Adm,H),(7-273,i-Bu,C-21,S,S,O,2-Adm,H),(7-274,i-Bu,C-22,S,S,O,2-Adm,H),(7-275,i-Bu,C-23,S,S,O,2-Adm,H),(7-276,i-Bu,C-24,S,S,O,2-Adm,H),(7-277,i-Bu,C-25,S,S,O,2-Adm,H),(7-278,i-Bu,C-26,S,S,O,2-Adm,H),(7-279,i-Bu,C-27,S,S,O,2-Adm,H),(7-280,i-Bu,C-28,S,S,O,2-Adm,H),(7-281,i-Bu,C-29,S,S,O,2-Adm,H),(7-282,i-Bu,C-30,S,S,O,2-Adm,H),(7-283,i-Bu,C-31,S,S,O,2-Adm,H),(7-284,i-Bu,C-32,S,S,O,2-Adm,H),(7-285,i-Bu,C-33,S,S,O,2-Adm,H),(7-286,i-Bu,C-34,S,S,O,2-Adm,H),(7-287,i-Bu,C-35,S,S,O,2-Adm,H),(7-288,i-Bu,C-36,S,S,O,2-Adm,H),(7-289,i-Bu,C-1,S,S,O,5-OH-2-Adm,H),(7-290,i-Bu,C-2,S,S,O,5-OH-2-Adm,H),(7-291,i-Bu,C-3,S,S,O,5-OH-2-Adm,H),(7-292,i-Bu,C-4,S,S,O,5-OH-2-Adm,H),(7-293,i-Bu,C-5,S,S,O,5-OH-2-Adm,H),(7-294,i-Bu,C-6,S,S,O,5-OH-2-Adm,H),(7-295,i-Bu,C-7,S,S,O,5-OH-2-Adm,H),(7-296,i-Bu,C-8,S,S,O,5-OH-2-Adm,H),(7-297,i-Bu,C-9,S,S,O,5-OH-2-Adm,H),(7-298,i-Bu,C-10,S,S,O,5-OH-2-Adm,H),(7-299,i-Bu,C-11,S,S,O,5-OH-2-Adm,H),(7-300,i-Bu,C-12,S,S,O,5-OH-2-Adm,H),(7-301,i-Bu,C-13,S,S,O,5-OH-2-Adm,H),(7-302,i-Bu,C-14,S,S,O,5-OH-2-Adm,H),(7-303,i-Bu,C-15,S,S,O,5-OH-2-Adm,H),(7-304,i-Bu,C-16,S,S,O,5-OH-2-Adm,H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,J-7,S,S,O,5-OH-2-Adm,H),(7-755,i-Bu,J-8,S,S,O,5-OH-2-Adm,H),(7-756,i-Bu,J-9,S,S,O,5-OH-2-Adm,H),(7-757,i-Bu,K-1,S,S,O,1-Adm,H),(7-758,i-Bu,K-2,S,S,O,1-Adm,H),(7-759,i-Bu,K-3,S,S,O,1-Adm,H),(7-760,i-Bu,K-4,S,S,O,1-Adm,H),(7-761,i-Bu,K-5,S,S,O,1-Adm,H),(7-762,i-Bu,K-6,S,S,O,1-Adm,H),(7-763,i-Bu,K-7,S,S,O,1-Adm,H),(7-764,i-Bu,K-8,S,S,O,1-Adm,H),(7-765,i-Bu,K-9,S,S,O,1-Adm,H),(7-766,i-Bu,K-1,S,S,O,2-Adm,H),(7-767,i-Bu,K-2,S,S,O,2-Adm,H),(7-768,i-Bu,K-3,S,S,O,2-Adm,H),(7-769,i-Bu,K-4,S,S,O,2-Adm,H),(7-770,i-Bu,K-5,S,S,O,2-Adm,H),(7-771,i-Bu,K-6,S,S,O,2-Adm,H),(7-772,i-Bu,K-7,S,S,O,2-Adm,H),(7-773,i-Bu,K-8,S,S,O,2-Adm,H),(7-774,i-Bu,K-9,S,S,O,2-Adm,H),(7-775,i-Bu,K-1,S,S,O,5-OH-2-Adm,H),(7-776,i-Bu,K-2,S,S,O,5-OH-2-Adm,H),(7-777,i-Bu,K-3,S,S,O,5-OH-2-Adm,H),(7-778,i-Bu,K-4,S,S,O,5-OH-2-Adm,H),(7-779,i-Bu,K-5,S,S,O,5-OH-2-Adm,H),(7-780,i-Bu,K-6,S,S,O,5-OH-2-Adm,H),(7-781,i-Bu,K-7,S,S,O,5-OH-2-Adm,H),(7-782,i-Bu,K-8,S,S,O,5-OH-2-Adm,H),(7-783,i-Bu,K-9,S,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(8-1,Pro,A-1,S,S,O,1-Adm,H),(8-2,Pro,A-2,S,S,O,1-Adm,H),(8-3,Pro,A-3,S,S,O,1-Adm,H),(8-4,Pro,A-4,S,S,O,1-Adm,H),(8-5,Pro,A-5,S,S,O,1-Adm,H),(8-6,Pro,A-6,S,S,O,1-Adm,H),(8-7,Pro,A-7,S,S,O,1-Adm,H),(8-8,Pro,A-8,S,S,O,1-Adm,H),(8-9,Pro,A-9,S,S,O,1-Adm,H),(8-10,Pro,A-10,S,S,O,1-Adm,H),(8-11,Pro,A-11,S,S,O,1-Adm,H),(8-12,Pro,A-12,S,S,O,1-Adm,H),(8-13,Pro,A-13,S,S,O,1-Adm,H),(8-14,Pro,A-14,S,S,O,1-Adm,H),(8-15,Pro,A-15,S,S,O,1-Adm,H),(8-16,Pro,A-16,S,S,O,1-Adm,H),(8-17,Pro,A-17,S,S,O,1-Adm,H),(8-18,Pro,A-18,S,S,O,1-Adm,H),(8-19,Pro,A-19,S,S,O,1-Adm,H),(8-20,Pro,A-20,S,S,O,1-Adm,H),(8-21,Pro,A-21,S,S,O,1-Adm,H),(8-22,Pro,A-22,S,S,O,1-Adm,H),(8-23,Pro,A-23,S,S,O,1-Adm,H),(8-24,Pro,A-24,S,S,O,1-Adm,H),(8-25,Pro,A-25,S,S,O,1-Adm,H),(8-26,Pro,A-26,S,S,O,1-Adm,H),(8-27,Pro,A-27,S,S,O,1-Adm,H),(8-28,Pro,A-28,S,S,O,1-Adm,H),(8-29,Pro,A-29,S,S,O,1-Adm,H),(8-30,Pro,A-30,S,S,O,1-Adm,H),(8-31,Pro,A-31,S,S,O,1-Adm,H),(8-32,Pro,A-32,S,S,O,1-Adm,H),(8-33,Pro,A-33,S,S,O,1-Adm,H),(8-34,Pro,A-34,S,S,O,1-Adm,H),(8-35,Pro,A-35,S,S,O,1-Adm,H),(8-36,Pro,A-36,S,S,O,1-Adm,H),(8-37,Pro,A-1,S,S,O,2-Adm,H),(8-38,Pro,A-2,S,S,O,2-Adm,H),(8-39,Pro,A-3,S,S,O,2-Adm,H),(8-40,Pro,A-4,S,S,O,2-Adm,H),(8-41,Pro,A-5,S,S,O,2-Adm,H),(8-42,Pro,A-6,S,S,O,2-Adm,H),(8-43,Pro,A-7,S,S,O,2-Adm,H),(8-44,Pro,A-9,S,S,O,2-Adm,H),(8-45,Pro,A-11,S,S,O,2-Adm,H),(8-46,Pro,A-12,S,S,O,2-Adm,H),(8-47,Pro,A-13,S,S,O,2-Adm,H),(8-48,Pro,A-14,S,S,O,2-Adm,H),(8-49,Pro,A-15,S,S,O,2-Adm,H),(8-50,Pro,A-16,S,S,O,2-Adm,H),(8-51,Pro,A-17,S,S,O,2-Adm,H),(8-52,Pro,A-18,S,S,O,2-Adm,H),(8-53,Pro,A-20,S,S,O,2-Adm,H),(8-54,Pro,A-21,S,S,O,2-Adm,H),(8-55,Pro,A-22,S,S,O,2-Adm,H),(8-56,Pro,A-23,S,S,O,2-Adm,H),(8-57,Pro,A-24,S,S,O,2-Adm,H),(8-58,Pro,A-26,S,S,O,2-Adm,H),(8-59,Pro,A-27,S,S,O,2-Adm,H),(8-60,Pro,A-28,S,S,O,2-Adm,H),(8-61,Pro,A-29,S,S,O,2-Adm,H),(8-62,Pro,A-30,S,S,O,2-Adm,H),(8-63,Pro,A-31,S,S,O,2-Adm,H),(8-64,Pro,A-32,S,S,O,2-Adm,H),(8-65,Pro,A-33,S,S,O,2-Adm,H),(8-66,Pro,A-34,S,S,O,2-Adm,H),(8-67,Pro,A-35,S,S,O,2-Adm,H),(8-68,Pro,A-36,S,S,O,2-Adm,H),(8-69,Pro,A-1,S,S,O,5-OH-2-Adm,H),(8-70,Pro,A-2,S,S,O,5-OH-2-Adm,H),(8-71,Pro,A-3,S,S,O,5-OH-2-Adm,H),(8-72,Pro,A-4,S,S,O,5-OH-2-Adm,H),(8-73,Pro,A-5,S,S,O,5-OH-2-Adm,H),(8-74,Pro,A-6,S,S,O,5-OH-2-Adm,H),(8-75,Pro,A-7,S,S,O,5-OH-2-Adm,H),(8-76,Pro,A-8,S,S,O,5-OH-2-Adm,H),(8-77,Pro,A-9,S,S,O,5-OH-2-Adm,H),(8-78,Pro,A-10,S,S,O,5-OH-2-Adm,H),(8-79,Pro,A-11,S,S,O,5-OH-2-Adm,H),(8-80,Pro,A-12,S,S,O,5-OH-2-Adm,H),(8-81,Pro,A-13,S,S,O,5-OH-2-Adm,H),(8-82,Pro,A-14,S,S,O,5-OH-2-Adm,H),(8-83,Pro,A-15,S,S,O,5-OH-2-Adm,H),(8-84,Pro,A-16,S,S,O,5-OH-2-Adm,H),(8-85,Pro,A-17,S,S,O,5-OH-2-Adm,H),(8-86,Pro,A-18,S,S,O,5-OH-2-Adm,H),(8-87,Pro,A-19,S,S,O,5-OH-2-Adm,H),(8-88,Pro,A-20,S,S,O,5-OH-2-Adm,H),(8-89,Pro,A-21,S,S,O,5-OH-2-Adm,H),(8-90,Pro,A-22,S,S,O,5-OH-2-Adm,H),(8-91,Pro,A-23,S,S,O,5-OH-2-Adm,H),(8-92,Pro,A-24,S,S,O,5-OH-2-Adm,H),(8-93,Pro,A-25,S,S,O,5-OH-2-Adm,H),(8-94,Pro,A-26,S,S,O,5-OH-2-Adm,H),(8-95,Pro,A-27,S,S,O,5-OH-2-Adm,H),(8-96,Pro,A-28,S,S,O,5-OH-2-Adm,H),(8-97,Pro,A-29,S,S,O,5-OH-2-Adm,H),(8-98,Pro,A-30,S,S,O,5-OH-2-Adm,H),(8-99,Pro,A-31,S,S,O,5-OH-2-Adm,H),(8-100,Pro,A-32,S,S,O,5-OH-2-Adm,H),(8-101,Pro,A-33,S,S,O,5-OH-2-Adm,H),(8-102,Pro,A-34,S,S,O,5-OH-2-Adm,H),(8-103,Pro,A-35,S,S,O,5-OH-2-Adm,H),(8-104,Pro,A-36,S,S,O,5-OH-2-Adm,H),(8-105,Pro,B-1,S,S,O,1-Adm,H),(8-106,Pro,B-2,S,S,O,1-Adm,H),(8-107,Pro,B-3,S,S,O,1-Adm,H),(8-108,Pro,B-4,S,S,O,1-Adm,H),(8-109,Pro,B-5,S,S,O,1-Adm,H),(8-110,Pro,B-6,S,S,O,1-Adm,H),(8-11,Pro,B-7,S,S,O,1-Adm,H),(8-112,Pro,B-8,S,S,O,1-Adm,H),(8-113,Pro,B-9,S,S,O,1-Adm,H),(8-114,Pro,B-10,S,S,O,1-Adm,H),(8-115,Pro,B-1,S,S,O,1-Adm,H),(8-116,Pro,B-12,S,S,O,1-Adm,H),(8-117,Pro,B-13,S,S,O,1-Adm,H),(8-118,Pro,B-14,S,S,O,1-Adm,H),(8-119,Pro,B-15,S,S,O,1-Adm,H),(8-120,Pro,B-16,S,S,O,1-Adm,H),(8-121,Pro,B-17,S,S,O,1-Adm,H),(8-122,Pro,B-18,S,S,O,1-Adm,H),(8-123,Pro,B-19,S,S,O,1-Adm,H),(8-124,Pro,B-20,S,S,O,1-Adm,H),(8-125,Pro,B-21,S,S,O,1-Adm,H),(8-126,Pro,B-22,S,S,O,1-Adm,H),(8-127,Pro,B-23,S,S,O,1-Adm,H),(8-128,Pro,B-24,S,S,O,1-Adm,H),(8-129,Pro,B-25,S,S,O,1-Adm,H),(8-130,Pro,B-26,S,S,O,1-Adm,H),(8-131,Pro,B-27,S,S,O,1-Adm,H),(8-132,Pro,B-28,S,S,O,1-Adm,H),(8-133,Pro,B-29,S,S,O,1-Adm,H),(8-134,Pro,B-30,S,S,O,1-Adm,H),(8-135,Pro,B-31,S,S,O,1-Adm,H),(8-136,Pro,B-32,S,S,O,1-Adm,H),(8-137,Pro,B-33,S,S,O,1-Adm,H),(8-138,Pro,B-34,S,S,O,1-Adm,H),(8-139,Pro,B-35,S,S,O,1-Adm,H),(8-140,Pro,B-36,S,S,O,1-Adm,H),(8-141,Pro,B-1,S,S,O,2-Adm,H),(8-142,Pro,B-2,S,S,O,2-Adm,H),(8-143,Pro,B-3,S,S,O,2-Adm,H),(8-144,Pro,B-4,S,S,O,2-Adm,H),(8-145,Pro,B-5,S,S,O,2-Adm,H),(8-146,Pro,B-6,S,S,O,2-Adm,H),(8-147,Pro,B-7,S,S,O,2-Adm,H),(8-148,Pro,B-8,S,S,O,2-Adm,H),(8-149,Pro,B-9,S,S,O,2-Adm,H),(8-150,Pro,B-10,S,S,O,2-Adm,H),(8-151,Pro,B-11,S,S,O,2-Adm,H),(8-152,Pro,B-12,S,S,O,2-Adm,H),(8-153,Pro,B-13,S,S,O,2-Adm,H),(8-154,Pro,B-14,S,S,O,2-Adm,H),(8-155,Pro,B-15,S,S,O,2-Adm,H),(8-156,Pro,B-16,S,S,O,2-Adm,H),(8-157,Pro,B-17,S,S,O,2-Adm,H),(8-158,Pro,B-18,S,S,O,2-Adm,H),(8-159,Pro,B-19,S,S,O,2-Adm,H),(8-160,Pro,B-20,S,S,O,2-Adm,H),(8-161,Pro,B-21,S,S,O,2-Adm,H),(8-162,Pro,B-22,S,S,O,2-Adm,H),(8-163,Pro,B-23,S,S,O,2-Adm,H),(8-164,Pro,B-24,S,S,O,2-Adm,H),(8-165,Pro,B-25,S,S,O,2-Adm,H),(8-166,Pro,B-26,S,S,O,2-Adm,H),(8-167,Pro,B-27,S,S,O,2-Adm,H),(8-168,Pro,B-28,S,S,O,2-Adm,H),(8-169,Pro,B-29,S,S,O,2-Adm,H),(8-170,Pro,B-30,S,S,O,2-Adm,H),(8-171,Pro,B-31,S,S,O,2-Adm,H),(8-172,Pro,B-32,S,S,O,2-Adm,H),(8-173,Pro,B-33,S,S,O,2-Adm,H),(8-174,Pro,B-34,S,S,O,2-Adm,H),(8-175,Pro,B-35,S,S,O,2-Adm,H),(8-176,Pro,B-36,S,S,O,2-Adm,H),(8-177,Pro,B-1,S,S,O,5-OH-2-Adm,H),(8-178,Pro,B-2,S,S,O,5-OH-2-Adm,H),(8-179,Pro,B-3,S,S,O,5-OH-2-Adm,H),(8-180,Pro,B-4,S,S,O,5-OH-2-Adm,H),(8-181,Pro,B-5,S,S,O,5-OH-2-Adm,H),(8-182,Pro,B-6,S,S,O,5-OH-2-Adm,H),(8-183,Pro,B-7,S,S,O,5-OH-2-Adm,H),(8-184,Pro,B-8,S,S,O,5-OH-2-Adm,H),(8-185,Pro,B-9,S,S,O,5-OH-2-Adm,H),(8-186,Pro,B-10,S,S,O,5-OH-2-Adm,H),(8-187,Pro,B-11,S,S,O,5-OH-2-Adm,H),(8-188,Pro,B-12,S,S,O,5-OH-2-Adm,H),(8-189,Pro,B-13,S,S,O,5-OH-2-Adm,H),(8-190,Pro,B-14,S,S,O,5-OH-2-Adm,H),(8-191,Pro,B-15,S,S,O,5-OH-2-Adm,H),(8-192,Pro,B-16,S,S,O,5-OH-2-Adm,H),(8-193,Pro,B-17,S,S,O,5-OH-2-Adm,H),(8-194,Pro,B-18,S,S,O,5-OH-2-Adm,H),(8-195,Pro,B-19,S,S,O,5-OH-2-Adm,H),(8-196,Pro,B-20,S,S,O,5-OH-2-Adm,H),(8-197,Pro,B-21,S,S,O,5-OH-2-Adm,H),(8-198,Pro,B-22,S,S,O,5-OH-2-Adm,H),(8-199,Pro,B-23,S,S,O,5-OH-2-Adm,H),(8-200,Pro,B-24,S,S,O,5-OH-2-Adm,H),(8-201,Pro,B-25,S,S,O,5-OH-2-Adm,H),(8-202,Pro,B-26,S,S,O,5-OH-2-Adm,H),(8-203,Pro,B-27,S,S,O,5-OH-2-Adm,H),(8-204,Pro,B-28,S,S,O,5-OH-2-Adm,H),(8-205,Pro,B-29,S,S,O,5-OH-2-Adm,H),(8-206,Pro,B-30,S,S,O,5-OH-2-Adm,H),(8-207,Pro,B-31,S,S,O,5-OH-2-Adm,H),(8-208,Pro,B-32,S,S,O,5-OH-2-Adm,H),(8-209,Pro,B-33,S,S,O,5-OH-2-Adm,H),(8-210,Pro,B-34,S,S,O,5-OH-2-Adm,H),(8-211,Pro,B-35,S,S,O,5-OH-2-Adm,H),(8-212,Pro,B-36,S,S,O,5-OH-2-Adm,H),(8-213,Pro,C-1,S,S,O,1-Adm,H),(8-214,Pro,C-2,S,S,O,1-Adm,H),(8-215,Pro,C-3,S,S,O,1-Adm,H),(8-216,Pro,C-4,S,S,O,1-Adm,H),(8-217,Pro,C-5,S,S,O,1-Adm,H),(8-218,Pro,C-6,S,S,O,1-Adm,H),(8-219,Pro,C-7,S,S,O,1-Adm,H),(8-220,Pro,C-8,S,S,O,1-Adm,H),(8-221,Pro,C-9,S,S,O,1-Adm,H),(8-222,Pro,C-10,S,S,O,1-Adm,H),(8-223,Pro,C-11,S,S,O,1-Adm,H),(8-224,Pro,C-12,S,S,O,1-Adm,H),(8-225,Pro,C-13,S,S,O,1-Adm,H),(8-226,Pro,C-14,S,S,O,1-Adm,H),(8-227,Pro,C-15,S,S,O,1-Adm,H),(8-228,Pro,C-16,S,S,O,1-Adm,H),(8-229,Pro,C-17,S,S,O,1-Adm,H),(8-230,Pro,C-18,S,S,O,1-Adm,H),(8-231,Pro,C-19,S,S,O,1-Adm,H),(8-232,Pro,C-20,S,S,O,1-Adm,H),(8-233,Pro,C-21,S,S,O,1-Adm,H),(8-234,Pro,C-22,S,S,O,1-Adm,H),(8-235,Pro,C-23,S,S,O,1-Adm,H),(8-236,Pro,C-24,S,S,O,1-Adm,H),(8-237,Pro,C-25,S,S,O,1-Adm,H),(8-238,Pro,C-26,S,S,O,1-Adm,H),(8-239,Pro,C-27,S,S,O,1-Adm,H),(8-240,Pro,C-28,S,S,O,1-Adm,H),(8-241,Pro,C-29,S,S,O,1-Adm,H),(8-242,Pro,C-30,S,S,O,1-Adm,H),(8-243,Pro,C-31,S,S,O,1-Adm,H),(8-244,Pro,C-32,S,S,O,1-Adm,H),(8-245,Pro,C-33,S,S,O,1-Adm,H),(8-246,Pro,C-34,S,S,O,1-Adm,H),(8-247,Pro,C-35,S,S,O,1-Adm,H),(8-248,Pro,C-36,S,S,O,1-Adm,H),(8-249,Pro,C-1,S,S,O,2-Adm,H),(8-250,Pro,C-2,S,S,O,2-Adm,H),(8-251,Pro,C-3,S,S,O,2-Adm,H),(8-252,Pro,C-4,S,S,O,2-Adm,H),(8-253,Pro,C-5,S,S,O,2-Adm,H),(8-254,Pro,C-6,S,S,O,2-Adm,H),(8-255,Pro,C-7,S,S,O,2-Adm,H),(8-256,Pro,C-8,S,S,O,2-Adm,H),(8-257,Pro,C-9,S,S,O,2-Adm,H),(8-258,Pro,C-10,S,S,O,2-Adm,H),(8-259,Pro,C-11,S,S,O,2-Adm,H),(8-260,Pro,C-12,S,S,O,2-Adm,H),(8-261,Pro,C-13,S,S,O,2-Adm,H),(8-262,Pro,C-14,S,S,O,2-Adm,H),(8-263,Pro,C-11,S,S,O,2-Adm,H),(8-264,Pro,C-16,S,S,O,2-Adm,H),(8-265,Pro,C-17,S,S,O,2-Adm,H),(8-266,Pro,C-18,S,S,O,2-Adm,H),(8-267,Pro,C-19,S,S,O,2-Adm,H),(8-268,Pro,C-20,S,S,O,2-Adm,H),(8-269,Pro,C-21,S,S,O,2-Adm,H),(8-270,Pro,C-22,S,S,O,2-Adm,H),(8-271,Pro,C-23,S,S,O,2-Adm,H),(8-272,Pro,C-24,S,S,O,2-Adm,H),(8-273,Pro,C-25,S,S,O,2-Adm,H),(8-274,Pro,C-26,S,S,O,2-Adm,H),(8-275,Pro,C-27,S,S,O,2-Adm,H),(8-276,Pro,C-28,S,S,O,2-Adm,H),(8-277,Pro,C-29,S,S,O,2-Adm,H),(8-278,Pro,C-30,S,S,O,2-Adm,H),(8-279,Pro,C-31,S,S,O,2-Adm,H),(8-280,Pro,C-32,S,S,O,2-Adm,H),(8-281,Pro,C-33,S,S,O,2-Adm,H),(8-282,Pro,C-34,S,S,O,2-Adm,H),(8-283,Pro,C-35,S,S,O,2-Adm,H),(8-284,Pro,C-36,S,S,O,2-Adm,H),(8-285,Pro,C-1,S,S,O,5-OH-2-Adm,H),(8-286,Pro,C-2,S,S,O,5-OH-2-Adm,H),(8-287,Pro,C-3,S,S,O,5-OH-2-Adm,H),(8-288,Pro,C-4,S,S,O,5-OH-2-Adm,H),(8-289,Pro,C-5,S,S,O,5-OH-2-Adm,H),(8-290,Pro,C-6,S,S,O,5-OH-2-Adm,H),(8-291,Pro,C-7,S,S,O,5-OH-2-Adm,H),(8-292,Pro,C-8,S,S,O,5-OH-2-Adm,H),(8-293,Pro,C-9,S,S,O,5-OH-2-Adm,H),(8-294,Pro,C-110,S,S,O,5-OH-2-Adm,H),(8-295,Pro,C-111,S,S,O,5-OH-2-Adm,H),(8-296,Pro,C-12,S,S,O,5-OH-2-Adm,H),(8-297,Pro,C-13,S,S,O,5-OH-2-Adm,H),(8-298,Pro,C-14,S,S,O,5-OH-2-Adm,H),(8-299,Pro,C-15,S,S,O,5-OH-2-Adm,H),(8-300,Pro,C-16,S,S,O,5-OH-2-Adm,H),(8-301,Pro,C-17,S,S,O,5-OH-2-Adm,H),(8-302,Pro,C-18,S,S,O,5-OH-2-Adm,H),(8-303,Pro,C-19,S,S,O,5-OH-2-Adm,H),(8-304,Pro,C-20,S,S,O,5-OH-2-Adm,H),(8-305,Pro,C-21,S,S,O,5-OH-2-Adm,H),(8-306,Pro,C-22,S,S,O,5-OH-2-Adm,H),(8-307,Pro,C-23,S,S,O,5-OH-2-Adm,H),(8-308,Pro,C-24,S,S,O,5-OH-2-Adm,H),(8-309,Pro,C-25,S,S,O,5-OH-2-Adm,H),(8-310,Pro,C-26,S,S,O,5-OH-2-Adm,H),(8-311,Pro,C-27,S,S,O,5-OH-2-Adm,H),(8-312,Pro,C-28,S,S,O,5-OH-2-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2-Adm,H),(8-623,Pro,F-15,S,S,O,5-OH-2-Adm,H),(8-624,Pro,F-16,S,S,O,5-OH-2-Adm,H),(8-625,Pro,F-17,S,S,O,5-OH-2-Adm,H),(8-626,Pro,F-18,S,S,O,5-OH-2-Adm,H),(8-627,Pro,F-19,S,S,O,5-OH-2-Adm,H),(8-628,Pro,F-20,S,S,O,5-OH-2-Adm,H),(8-629,Pro,F-21,S,S,O,5-OH-2-Adm,H),(8-630,Pro,F-22,S,S,O,5-OH-2-Adm,H),(8-631,Pro,F-23,S,S,O,5-OH-2-Adm,H),(8-632,Pro,F-24,S,S,O,5-OH-2-Adm,H),(8-633,Pro,F-25,S,S,O,5-OH-2-Adm,H),(8-634,Pro,F-26,S,S,O,5-OH-2-Adm,H),(8-635,Pro,F-27,S,S,O,5-OH-2-Adm,H),(8-636,Pro,F-28,S,S,O,5-OH-2-Adm,H),(8-637,Pro,F-29,S,S,O,5-OH-2-Adm,H),(8-638,Pro,F-30,S,S,O,5-OH-2-Adm,H),(8-639,Pro,F-31,S,S,O,5-OH-2-Adm,H),(8-640,Pro,F-32,S,S,O,5-OH-2-Adm,H),(8-641,Pro,F-33,S,S,O,5-OH-2-Adm,H),(8-642,Pro,F-34,S,S,O,5-OH-2-Adm,H),(8-643,Pro,F-35,S,S,O,5-OH-2-Adm,H),(8-644,Pro,F-36,S,S,O,5-OH-2-Adm,H),(8-645,Pro,G-1,S,S,O,1-Adm,H),(8-646,Pro,G-2,S,S,O,1-Adm,H),(8-647,Pro,G-3,S,S,O,1-Adm,H),(8-648,Pro,G-4,S,S,O,1-Adm,H),(8-649,Pro,G-5,S,S,O,1-Adm,H),(8-650,Pro,G-6,S,S,O,1-Adm,H),(8-651,Pro,G-7,S,S,O,1-Adm,H),(8-652,Pro,G-8,S,S,O,1-Adm,H),(8-653,Pro,G-9,S,S,O,1-Adm,H),(8-654,Pro,G-1,S,S,O,2-Adm,H),(8-655,Pro,G-2,S,S,O,2-Adm,H),(8-656,Pro,G-3,S,S,O,2-Adm,H),(8-657,Pro,G-4,S,S,O,2-Adm,H),(8-658,Pro,G-5,S,S,O,2-Adm,H),(8-659,Pro,G-6,S,S,O,2-Adm,H),(8-660,Pro,G-7,S,S,O,2-Adm,H),(8-661,Pro,G-8,S,S,O,2-Adm,H),(8-662,Pro,G-9,S,S,O,2-Adm,H),(8-663,Pro,G-1,S,S,O,5-OH-2-Adm,H),(8-664,Pro,G-2,S,S,O,5-OH-2-Adm,H),(8-665,Pro,G-3,S,S,O,5-OH-2-Adm,H),(8-666,Pro,G-4,S,S,O,5-OH-2-Adm,H),(8-667,Pro,G-5,S,S,O,5-OH-2-Adm,H),(8-668,Pro,G-6,S,S,O,5-OH-2-Adm,H),(8-669,Pro,G-7,S,S,O,5-OH-2-Adm,H),(8-670,Pro,G-8,S,S,O,5-OH-2-Adm,H),(8-671,Pro,G-9,S,S,O,5-OH-2-Adm,H),(8-672,Pro,H-1,S,S,O,1-Adm,H),(8-673,Pro,H-2,S,S,O,1-Adm,H),(8-674,Pro,H-3,S,S,O,1-Adm,H),(8-675,Pro,H-4,S,S,O,1-Adm,H),(8-676,Pro,H-5,S,S,O,1-Adm,H),(8-677,Pro,H-6,S,S,O,1-Adm,H),(8-678,Pro,H-7,S,S,O,1-Adm,H),(8-679,Pro,H-8,S,S,O,1-Adm,H),(8-680,Pro,H-9,S,S,O,1-Adm,H),(8-681,Pro,H-1,S,S,O,2-Adm,H),(8-682,Pro,H-2,S,S,O,2-Adm,H),(8-683,Pro,H-3,S,S,O,2-Adm,H),(8-684,Pro,H-4,S,S,O,2-Adm,H),(8-685,Pro,H-5,S,S,O,2-Adm,H),(8-686,Pro,H-6,S,S,O,2-Adm,H),(8-687,Pro,H-7,S,S,O,2-Adm,H),(8-688,Pro,H-8,S,S,O,2-Adm,H),(8-689,Pro,H-9,S,S,O,2-Adm,H),(8-690,Pro,H-1,S,S,O,5-OH-2-Adm,H),(8-691,Pro,H-2,S,S,O,5-OH-2-Adm,H),(8-692,Pro,H-3,S,S,O,5-OH-2-Adm,H),(8-693,Pro,H-4,S,S,O,5-OH-2-Adm,H),(8-694,Pro,H-5,S,S,O,5-OH-2-Adm,H),(8-695,Pro,H-6,S,S,O,5-OH-2-Adm,H),(8-696,Pro,H-7,S,S,O,5-OH-2-Adm,H),(8-697,Pro,H-8,S,S,O,5-OH-2-Adm,H),(8-698,Pro,H-9,S,S,O,5-OH-2-Adm,H),(8-699,Pro,I-1,S,S,O,1-Adm,H),(8-700,Pro,I-2,S,S,O,1-Adm,H),(8-701,Pro,I-3,S,S,O,1-Adm,H),(8-702,Pro,I-4,S,S,O,1-Adm,H),(8-703,Pro,I-5,S,S,O,1-Adm,H),(8-704,Pro,I-6,S,S,O,1-Adm,H),(8-705,Pro,I-7,S,S,O,1-Adm,H),(8-706,Pro,I-8,S,S,O,1-Adm,H),(8-707,Pro,I-9,S,S,O,1-Adm,H),(8-708,Pro,I-1,S,S,O,2-Adm,H),(8-709,Pro,I-2,S,S,O,2-Adm,H),(8-710,Pro,I-3,S,S,O,2-Adm,H),(8-711,Pro,I-4,S,S,O,2-Adm,H),(8-712,Pro,I-5,S,S,O,2-Adm,H),(8-713,Pro,I-6,S,S,O,2-Adm,H),(8-714,Pro,I-7,S,S,O,2-Adm,H),(8-715,Pro,I-8,S,S,O,2-Adm,H),(8-716,Pro,I-9,S,S,O,2-Adm,H),(8-717,Pro,I-1,S,S,O,5-OH-2-Adm,H),(8-718,Pro,I-2,S,S,O,5-OH-2-Adm,H),(8-719,Pro,I-3,S,S,O,5-OH-2-Adm,H),(8-720,Pro,I-4,S,S,O,5-OH-2-Adm,H),(8-721,Pro,I-5,S,S,O,5-OH-2-Adm,H),(8-722,Pro,I-6,S,S,O,5-OH-2-Adm,H),(8-723,Pro,I-7,S,S,O,5-OH-2-Adm,H),(8-724,Pro,I-8,S,S,O,5-OH-2-Adm,H),(8-725,Pro,I-9,S,S,O,5-OH-2-Adm,H),(8-726,Pro,J-1,S,S,O,1-Adm,H),(8-727,Pro,J-2,S,S,O,1-Adm,H),(8-728,Pro,J-3,S,S,O,1-Adm,H),(8-729,Pro,J-4,S,S,O,1-Adm,H),(8-730,Pro,J-5,S,S,O,1-Adm,H),(8-731,Pro,J-6,S,S,O,1-Adm,H),(8-732,Pro,J-7,S,S,O,1-Adm,H),(8-733,Pro,J-8,S,S,O,1-Adm,H),(8-734,Pro,J-9,S,S,O,1-Adm,H),(8-735,Pro,J-1,S,S,O,2-Adm,H),(8-736,Pro,J-2,S,S,O,2-Adm,H),(8-737,Pro,J-3,S,S,O,2-Adm,H),(8-738,Pro,J-4,S,S,O,2-Adm,H),(8-739,Pro,J-5,S,S,O,2-Adm,H),(8-740,Pro,J-6,S,S,O,2-Adm,H),(8-741,Pro,J-7,S,S,O,2-Adm,H),(8-742,Pro,J-8,S,S,O,2-Adm,H),(8-743,Pro,J-9,S,S,O,2-Adm,H),(8-744,Pro,J-1,S,S,O,5-OH-2-Adm,H),(8-745,Pro,J-2,S,S,O,5-OH-2-Adm,H),(8-746,Pro,J-3,S,S,O,5-OH-2-Adm,H),(8-747,Pro,J-4,S,S,O,5-OH-2-Adm,H),(8-748,Pro,J-5,S,S,O,5-OH-2-Adm,H),(8-749,Pro,J-6,S,S,O,5-OH-2-Adm,H),(8-750,Pro,J-7,S,S,O,5-OH-2-Adm,H),(8-751,Pro,J-8,S,S,O,5-OH-2-Adm,H),(8-752,Pro,J-9,S,S,O,5-OH-2-Adm,H),(8-753,Pro,K-1,S,S,O,1-Adm,H),(8-754,Pro,K-2,S,S,O,1-Adm,H),(8-755,Pro,K-3,S,S,O,1-Adm,H),(8-756,Pro,K-4,S,S,O,1-Adm,H),(8-757,Pro,K-5,S,S,O,1-Adm,H),(8-758,Pro,K-6,S,S,O,1-Adm,H),(8-759,Pro,K-7,S,S,O,1-Adm,H),(8-760,Pro,K-8,S,S,O,1-Adm,H),(8-761,Pro,K-9,S,S,O,1-Adm,H),(8-762,Pro,K-1,S,S,O,2-Adm,H),(8-763,Pro,K-2,S,S,O,2-Adm,H),(8-764,Pro,K-3,S,S,O,2-Adm,H),(8-765,Pro,K-4,S,S,O,2-Adm,H),(8-766,Pro,K-5,S,S,O,2-Adm,H),(8-767,Pro,K-6,S,S,O,2-Adm,H),(8-768,Pro,K-7,S,S,O,2-Adm,H),(8-769,Pro,K-8,S,S,O,2-Adm,H),(8-770,Pro,K-9,S,S,O,2-Adm,H),(8-771,Pro,K-1,S,S,O,5-OH-2-Adm,H),(8-772,Pro,K-2,S,S,O,5-OH-2-Adm,H),(8-773,Pro,K-3,S,S,O,5-OH-2-Adm,H),(8-774,Pro,K-4,S,S,O,5-OH-2-Adm,H),(8-775,Pro,K-5,S,S,O,5-OH-2-Adm,H),(8-776,Pro,K-6,S,S,O,5-OH-2-Adm,H),(8-777,Pro,K-7,S,S,O,5-OH-2-Adm,H),(8-778,Pro,K-8,S,S,O,5-OH-2-Adm,H),(8-779,Pro,K-9,S,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(9-1,i-Pro,A-1,S,S,O,1-Adm,H),(9-2,i-Pro,A-2,S,S,O,1-Adm,H),(9-3,i-Pro,A-3,S,S,O,1-Adm,H),(9-4,i-Pro,A-4,S,S,O,1-Adm,H),(9-5,i-Pro,A-5,S,S,O,1-Adm,H),(9-6,i-Pro,A-6,S,S,O,1-Adm,H),(9-7,i-Pro,A-7,S,S,O,1-Adm,H),(9-8,i-Pro,A-8,S,S,O,1-Adm,H),(9-9,i-Pro,A-9,S,S,O,1-Adm,H),(9-10,i-Pro,A-10,S,S,O,1-Adm,H),(9-11,i-Pro,A-11,S,S,O,1-Adm,H),(9-12,i-Pro,A-12,S,S,O,1-Adm,H),(9-13,i-Pro,A-13,S,S,O,1-Adm,H),(9-14,i-Pro,A-14,S,S,O,1-Adm,H),(9-15,i-Pro,A-15,S,S,O,1-Adm,H),(9-16,i-Pro,A-16,S,S,O,1-Adm,H),(9-17,i-Pro,A-17,S,S,O,1-Adm,H),(9-18,i-Pro,A-18,S,S,O,1-Adm,H),(9-19,i-Pro,A-19,S,S,O,1-Adm,H),(9-20,i-Pro,A-20,S,S,O,1-Adm,H),(9-21,i-Pro,A-21,S,S,O,1-Adm,H),(9-22,i-Pro,A-22,S,S,O,1-Adm,H),(9-23,i-Pro,A-23,S,S,O,1-Adm,H),(9-24,i-Pro,A-24,S,S,O,1-Adm,H),(9-25,i-Pro,A-25,S,S,O,1-Adm,H),(9-26,i-Pro,A-26,S,S,O,1-Adm,H),(9-27,i-Pro,A-27,S,S,O,1-Adm,H),(9-28,i-Pro,A-28,S,S,O,1-Adm,H),(9-29,i-Pro,A-29,S,S,O,1-Adm,H),(9-30,i-Pro,A-30,S,S,O,1-Adm,H),(9-31,i-Pro,A-31,S,S,O,1-Adm,H),(9-32,i-Pro,A-32,S,S,O,1-Adm,H),(9-33,i-Pro,A-33,S,S,O,1-Adm,H),(9-34,i-Pro,A-34,S,S,O,1-Adm,H),(9-35,i-Pro,A-35,S,S,O,1-Adm,H),(9-36,i-Pro,A-36,S,S,O,1-Adm,H),(9-37,i-Pro,A-1,S,S,O,2-Adm,H),(9-38,i-Pro,A-2,S,S,O,2-Adm,H),(9-39,i-Pro,A-3,S,S,O,2-Adm,H),(9-40,i-Pro,A-4,S,S,O,2-Adm,H),(9-41,i-Pro,A-5,S,S,O,2-Adm,H),(9-42,i-Pro,A-6,S,S,O,2-Adm,H),(9-43,i-Pro,A-7,S,S,O,2-Adm,H),(9-44,i-Pro,A-9,S,S,O,2-Adm,H),(9-45,i-Pro,A-11,S,S,O,2-Adm,H),(9-46,i-Pro,A-12,S,S,O,2-Adm,H),(9-47,i-Pro,A-13,S,S,O,2-Adm,H),(9-48,i-Pro,A-14,S,S,O,2-Adm,H),(9-49,i-Pro,A-15,S,S,O,2-Adm,H),(9-50,i-Pro,A-16,S,S,O,2-Adm,H),(9-51,i-Pro,A-17,S,S,O,2-Adm,H),(9-52,i-Pro,A-18,S,S,O,2-Adm,H),(9-53,i-Pro,A-20,S,S,O,2-Adm,H),(9-54,i-Pro,A-21,S,S,O,2-Adm,H),(9-55,i-Pro,A-22,S,S,O,2-Adm,H),(9-56,i-Pro,A-23,S,S,O,2-Adm,H),(9-57,i-Pro,A-24,S,S,O,2-Adm,H),(9-58,i-Pro,A-26,S,S,O,2-Adm,H),(9-59,i-Pro,A-27,S,S,O,2-Adm,H),(9-60,i-Pro,A-28,S,S,O,2-Adm,H),(9-61,i-Pro,A-29,S,S,O,2-Adm,H),(9-62,i-Pro,A-30,S,S,O,2-Adm,H),(9-63,i-Pro,A-31,S,S,O,2-Adm,H),(9-64,i-Pro,A-32,S,S,O,2-Adm,H),(9-65,i-Pro,A-33,S,S,O,2-Adm,H),(9-66,i-Pro,A-34,S,S,O,2-Adm,H),(9-67,i-Pro,A-35,S,S,O,2-Adm,H),(9-68,i-Pro,A-36,S,S,O,2-Adm,H),(9-69,i-Pro,A-1,S,S,O,5-OH-2-Adm,H),(9-70,i-Pro,A-2,S,S,O,5-OH-2-Adm,H),(9-71,i-Pro,A-3,S,S,O,5-OH-2-Adm,H),(9-72,i-Pro,A-4,S,S,O,5-OH-2-Adm,H),(9-73,i-Pro,A-5,S,S,O,5-OH-2-Adm,H),(9-74,i-Pro,A-6,S,S,O,5-OH-2-Adm,H),(9-75,i-Pro,A-7,S,S,O,5-OH-2-Adm,H),(9-76,i-Pro,A-8,S,S,O,5-OH-2-Adm,H),(9-77,i-Pro,A-9,S,S,O,5-OH-2-Adm,H),(9-78,i-Pro,A-10,S,S,O,5-OH-2-Adm,H),(9-79,i-Pro,A-11,S,S,O,5-OH-2-Adm,H),(9-80,i-Pro,A-12,S,S,O,5-OH-2-Adm,H),(9-81,i-Pro,A-13,S,S,O,5-OH-2-Adm,H),(9-82,i-Pro,A-14,S,S,O,5-OH-2-Adm,H),(9-83,i-Pro,A-15,S,S,O,5-OH-2-Adm,H),(9-84,i-Pro,A-16,S,S,O,5-OH-2-Adm,H),(9-85,i-Pro,A-17,S,S,O,5-OH-2-Adm,H),(9-86,i-Pro,A-18,S,S,O,5-OH-2-Adm,H),(9-87,i-Pro,A-19,S,S,O,5-OH-2-Adm,H),(9-88,i-Pro,A-20,S,S,O,5-OH-2-Adm,H),(9-89,i-Pro,A-21,S,S,O,5-OH-2-Adm,H),(9-90,i-Pro,A-22,S,S,O,5-OH-2-Adm,H),(9-91,i-Pro,A-23,S,S,O,5-OH-2-Adm,H),(9-92,i-Pro,A-24,S,S,O,5-OH-2-Adm,H),(9-93,i-Pro,A-25,S,S,O,5-OH-2-Adm,H),(9-94,i-Pro,A-26,S,S,O,5-OH-2-Adm,H),(9-95,i-Pro,A-27,S,S,O,5-OH-2-Adm,H),(9-96,i-Pro,A-28,S,S,O,5-OH-2-Adm,H),(9-97,i-Pro,A-29,S,S,O,5-OH-2-Adm,H),(9-98,i-Pro,A-30,S,S,O,5-OH-2-Adm,H),(9-99,i-Pro,A-31,S,S,O,5-OH-2-Adm,H),(9-100,i-Pro,A-32,S,S,O,5-OH-2-Adm,H),(9-101,i-Pro,A-33,S,S,O,5-OH-2-Adm,H),(9-102,i-Pro,A-34,S,S,O,5-OH-2-Adm,H),(9-103,i-Pro,A-35,S,S,O,5-OH-2-Adm,H),(9-104,i-Pro,A-36,S,S,O,5-OH-2-Adm,H),(9-105,i-Pro,B-1,S,S,O,1-Adm,H),(9-106,i-Pro,B-2,S,S,O,1-Adm,H),(9-107,i-Pro,B-3,S,S,O,1-Adm,H),(9-108,i-Pro,B-4,S,S,O,1-Adm,H),(9-109,i-Pro,B-5,S,S,O,1-Adm,H),(9-110,i-Pro,B-6,S,S,O,1-Adm,H),(9-111,i-Pro,B-7,S,S,O,1-Adm,H),(9-112,i-Pro,B-8,S,S,O,1-Adm,H),(9-113,i-Pro,B-9,S,S,O,1-Adm,H),(9-114,i-Pro,B-10,S,S,O,1-Adm,H),(9-115,i-Pro,B-11,S,S,O,1-Adm,H),(9-116,i-Pro,B-12,S,S,O,1-Adm,H),(9-117,i-Pro,B-13,S,S,O,1-Adm,H),(9-118,i-Pro,B-14,S,S,O,1-Adm,H),(9-119,i-Pro,B-15,S,S,O,1-Adm,H),(9-120,i-Pro,B-16,S,S,O,1-Adm,H),(9-121,i-Pro,B-17,S,S,O,1-Adm,H),(9-122,i-Pro,B-18,S,S,O,1-Adm,H),(9-123,i-Pro,B-19,S,S,O,1-Adm,H),(9-124,i-Pro,B-20,S,S,O,1-Adm,H),(9-125,i-Pro,B-21,S,S,O,1-Adm,H),(9-126,i-Pro,B-22,S,S,O,1-Adm,H),(9-127,i-Pro,B-23,S,S,O,1-Adm,H),(9-128,i-Pro,B-24,S,S,O,1-Adm,H),(9-129,i-Pro,B-25,S,S,O,1-Adm,H),(9-130,i-Pro,B-26,S,S,O,1-Adm,H),(9-131,i-Pro,B-27,S,S,O,1-Adm,H),(9-132,i-Pro,B-28,S,S,O,1-Adm,H),(9-133,i-Pro,B-29,S,S,O,1-Adm,H),(9-134,i-Pro,B-30,S,S,O,1-Adm,H),(9-135,i-Pro,B-31,S,S,O,1-Adm,H),(9-136,i-Pro,B-32,S,S,O,1-Adm,H),(9-137,i-Pro,B-33,S,S,O,1-Adm,H),(9-138,i-Pro,B-34,S,S,O,1-Adm,H),(9-139,i-Pro,B-35,S,S,O,1-Adm,H),(9-140,i-Pro,B-36,S,S,O,1-Adm,H),(9-141,i-Pro,B-1,S,S,O,2-Adm,H),(9-142,i-Pro,B-2,S,S,O,2-Adm,H),(9-143,i-Pro,B-3,S,S,O,2-Adm,H),(9-144,i-Pro,B-4,S,S,O,2-Adm,H),(9-145,i-Pro,B-5,S,S,O,2-Adm,H),(9-146,i-Pro,B-6,S,S,O,2-Adm,H),(9-147,i-Pro,B-7,S,S,O,2-Adm,H),(9-148,i-Pro,B-8,S,S,O,2-Adm,H),(9-149,i-Pro,B-9,S,S,O,2-Adm,H),(9-150,i-Pro,B-110,S,S,O,2-Adm,H),(9-151,i-Pro,B-11,S,S,O,2-Adm,H),(9-152,i-Pro,B-12,S,S,O,2-Adm,H),(9-153,i-Pro,B-13,S,S,O,2-Adm,H),(9-154,i-Pro,B-14,S,S,O,2-Adm,H),(9-155,i-Pro,B-15,S,S,O,2-Adm,H),(9-156,i-Pro,B-16,S,S,O,2-Adm,H),(9-157,i-Pro,B-17,S,S,O,2-Adm,H),(9-158,i-Pro,B-18,S,S,O,2-Adm,H),(9-159,i-Pro,B-19,S,S,O,2-Adm,H),(9-160,i-Pro,B-20,S,S,O,2-Adm,H),(9-161,i-Pro,B-21,S,S,O,2-Adm,H),(9-162,i-Pro,B-22,S,S,O,2-Adm,H),(9-163,i-Pro,B-23,S,S,O,2-Adm,H),(9-164,i-Pro,B-24,S,S,O,2-Adm,H),(9-165,i-Pro,B-25,S,S,O,2-Adm,H),(9-166,i-Pro,B-26,S,S,O,2-Adm,H),(9-167,i-Pro,B-27,S,S,O,2-Adm,H),(9-168,i-Pro,B-28,S,S,O,2-Adm,H),(9-169,i-Pro,B-29,S,S,O,2-Adm,H),(9-170,i-Pro,B-30,S,S,O,2-Adm,H),(9-171,i-Pro,B-31,S,S,O,2-Adm,H),(9-172,i-Pro,B-32,S,S,O,2-Adm,H),(9-173,i-Pro,B-33,S,S,O,2-Adm,H),(9-174,i-Pro,B-34,S,S,O,2-Adm,H),(9-175,i-Pro,B-35,S,S,O,2-Adm,H),(9-176,i-Pro,B-36,S,S,O,2-Adm,H),(9-177,i-Pro,B-1,S,S,O,5-OH-2-Adm,H),(9-178,i-Pro,B-2,S,S,O,5-OH-2-Adm,H),(9-179,i-Pro,B-3,S,S,O,5-OH-2-Adm,H),(9-180,i-Pro,B-4,S,S,O,5-OH-2-Adm,H),(9-181,i-Pro,B-5,S,S,O,5-OH-2-Adm,H),(9-182,i-Pro,B-6,S,S,O,5-OH-2-Adm,H),(9-183,i-Pro,B-7,S,S,O,5-OH-2-Adm,H),(9-184,i-Pro,B-8,S,S,O,5-OH-2-Adm,H),(9-185,i-Pro,B-9,S,S,O,5-OH-2-Adm,H),(9-186,i-Pro,B-10,S,S,O,5-OH-2-Adm,H),(9-187,i-Pro,B-11,S,S,O,5-OH-2-Adm,H),(9-188,i-Pro,B-12,S,S,O,5-OH-2-Adm,H),(9-189,i-Pro,B-13,S,S,O,5-OH-2-Adm,H),(9-190,i-Pro,B-14,S,S,O,5-OH-2-Adm,H),(9-191,i-Pro,B-15,S,S,O,5-OH-2-Adm,H),(9-192,i-Pro,B-16,S,S,O,5-OH-2-Adm,H),(9-193,i-Pro,B-17,S,S,O,5-OH-2-Adm,H),(9-194,i-Pro,B-18,S,S,O,5-OH-2-Adm,H),(9-195,i-Pro,B-19,S,S,O,5-OH-2-Adm,H),(9-196,i-Pro,B-20,S,S,O,5-OH-2-Adm,H),(9-197,i-Pro,B-21,S,S,O,5-OH-2-Adm,H),(9-198,i-Pro,B-22,S,S,O,5-OH-2-Adm,H),(9-199,i-Pro,B-23,S,S,O,5-OH-2-Adm,H),(9-200,i-Pro,B-24,S,S,O,5-OH-2-Adm,H),(9-201,i-Pro,B-25,S,S,O,5-OH-2-Adm,H),(9-202,i-Pro,B-26,S,S,O,5-OH-2-Adm,H),(9-203,i-Pro,B-27,S,S,O,5-OH-2-Adm,H),(9-204,i-Pro,B-28,S,S,O,5-OH-2-Adm,H),(9-205,i-Pro,B-29,S,S,O,5-OH-2-Adm,H),(9-206,i-Pro,B-30,S,S,O,5-OH-2-Adm,H),(9-207,i-Pro,B-31,S,S,O,5-OH-2-Adm,H),(9-208,i-Pro,B-32,S,S,O,5-OH-2-Adm,H),(9-209,i-Pro,B-33,S,S,O,5-OH-2-Adm,H),(9-210,i-Pro,B-34,S,S,O,5-OH-2-Adm,H),(9-211,i-Pro,B-35,S,S,O,5-OH-2-Adm,H),(9-212,i-Pro,B-36,S,S,O,5-OH-2-Adm,H),(9-213,i-Pro,C-1,S,S,O,1-Adm,H),(9-214,i-Pro,C-2,S,S,O,1-Adm,H),(9-215,i-Pro,C-3,S,S,O,1-Adm,H),(9-216,i-Pro,C-4,S,S,O,1-Adm,H),(9-217,i-Pro,C-5,S,S,O,1-Adm,H),(9-218,i-Pro,C-6,S,S,O,1-Adm,H),(9-219,i-Pro,C-7,S,S,O,1-Adm,H),(9-220,i-Pro,C-8,S,S,O,1-Adm,H),(9-221,i-Pro,C-9,S,S,O,1-Adm,H),(9-222,i-Pro,C-11,S,S,O,1-Adm,H),(9-223,i-Pro,C-11,S,S,O,1-Adm,H),(9-224,i-Pro,C-12,S,S,O,1-Adm,H),(9-225,i-Pro,C-13,S,S,O,1-Adm,H),(9-226,i-Pro,C-14,S,S,O,1-Adm,H),(9-227,i-Pro,C-15,S,S,O,1-Adm,H),(9-228,i-Pro,C-16,S,S,O,1-Adm,H),(9-229,i-Pro,C-17,S,S,O,1-Adm,H),(9-230,i-Pro,C-18,S,S,O,1-Adm,H),(9-231,i-Pro,C-19,S,S,O,1-Adm,H),(9-232,i-Pro,C-20,S,S,O,1-Adm,H),(9-233,i-Pro,C-21,S,S,O,1-Adm,H),(9-234,i-Pro,C-22,S,S,O,1-Adm,H),(9-235,i-Pro,C-23,S,S,O,1-Adm,H),(9-236,i-Pro,C-24,S,S,O,1-Adm,H),(9-237,i-Pro,C-25,S,S,O,1-Adm,H),(9-238,i-Pro,C-26,S,S,O,1-Adm,H),(9-239,i-Pro,C-27,S,S,O,1-Adm,H),(9-240,i-Pro,C-28,S,S,O,1-Adm,H),(9-241,i-Pro,C-29,S,S,O,1-Adm,H),(9-242,i-Pro,C-30,S,S,O,1-Adm,H),(9-243,i-Pro,C-31,S,S,O,1-Adm,H),(9-244,i-Pro,C-32,S,S,O,1-Adm,H),(9-245,i-Pro,C-33,S,S,O,1-Adm,H),(9-246,i-Pro,C-34,S,S,O,1-Adm,H),(9-247,i-Pro,C-35,S,S,O,1-Adm,H),(9-248,i-Pro,C-36,S,S,O,1-Adm,H),(9-249,i-Pro,C-1,S,S,O,2-Adm,H),(9-250,i-Pro,C-2,S,S,O,2-Adm,H),(9-251,i-Pro,C-3,S,S,O,2-Adm,H),(9-252,i-Pro,C-4,S,S,O,2-Adm,H),(9-253,i-Pro,C-5,S,S,O,2-Adm,H),(9-254,i-Pro,C-6,S,S,O,2-Adm,H),(9-255,i-Pro,C-7,S,S,O,2-Adm,H),(9-256,i-Pro,C-8,S,S,O,2-Adm,H),(9-257,i-Pro,C-9,S,S,O,2-Adm,H),(9-258,i-Pro,C-100,S,S,O,2-Adm,H),(9-259,i-Pro,C-11,S,S,O,2-Adm,H),(9-260,i-Pro,C-12,S,S,O,2-Adm,H),(9-261,i-Pro,C-13,S,S,O,2-Adm,H),(9-262,i-Pro,C-14,S,S,O,2-Adm,H),(9-263,i-Pro,C-15,S,S,O,2-Adm,H),(9-264,i-Pro,C-16,S,S,O,2-Adm,H),(9-265,i-Pro,C-17,S,S,O,2-Adm,H),(9-266,i-Pro,C-18,S,S,O,2-Adm,H),(9-267,i-Pro,C-19,S,S,O,2-Adm,H),(9-268,i-Pro,C-20,S,S,O,2-Adm,H),(9-269,i-Pro,C-21,S,S,O,2-Adm,H),(9-270,i-Pro,C-22,S,S,O,2-Adm,H),(9-271,i-Pro,C-23,S,S,O,2-Adm,H),(9-272,i-Pro,C-24,S,S,O,2-Adm,H),(9-273,i-Pro,C-25,S,S,O,2-Adm,H),(9-274,i-Pro,C-26,S,S,O,2-Adm,H),(9-275,i-Pro,C-27,S,S,O,2-Adm,H),(9-276,i-Pro,C-28,S,S,O,2-Adm,H),(9-277,i-Pro,C-29,S,S,O,2-Adm,H),(9-278,i-Pro,C-30,S,S,O,2-Adm,H),(9-279,i-Pro,C-31,S,S,O,2-Adm,H),(9-280,i-Pro,C-32,S,S,O,2-Adm,H),(9-281,i-Pro,C-33,S,S,O,2-Adm,H),(9-282,i-Pro,C-34,S,S,O,2-Adm,H),(9-283,i-Pro,C-35,S,S,O,2-Adm,H),(9-284,i-Pro,C-36,S,S,O,2-Adm,H),(9-285,i-Pro,C-1,S,S,O,5-OH-2-Adm,H),(9-286,i-Pro,C-2,S,S,O,5-OH-2-Adm,H),(9-287,i-Pro,C-3,S,S,O,5-OH-2-Adm,H),(9-288,i-Pro,C-4,S,S,O,5-OH-2-Adm,H),(9-289,i-Pro,C-5,S,S,O,5-OH-2-Adm,H),(9-290,i-Pro,C-6,S,S,O,5-OH-2-Adm,H),(9-291,i-Pro,C-7,S,S,O,5-OH-2-Adm,H),(9-292,i-Pro,C-8,S,S,O,5-OH-2-Adm,H),(9-293,i-Pro,C-9,S,S,O,5-OH-2-Adm,H),(9-294,i-Pro,C-11,S,S,O,5-OH-2-Adm,H),(9-295,i-Pro,C-11,S,S,O,5-OH-2-Adm,H),(9-296,i-Pro,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Adm,H),(9-732,i-Pro,J-7,S,S,O,1-Adm,H),(9-733,i-Pro,J-8,S,S,O,1-Adm,H),(9-734,i-Pro,J-9,S,S,O,1-Adm,H),(9-735,i-Pro,J-1,S,S,O,2-Adm,H),(9-736,i-Pro,J-2,S,S,O,2-Adm,H),(9-737,i-Pro,J-3,S,S,O,2-Adm,H),(9-738,i-Pro,J-4,S,S,O,2-Adm,H),(9-739,i-Pro,J-5,S,S,O,2-Adm,H),(9-740,i-Pro,J-6,S,S,O,2-Adm,H),(9-741,i-Pro,J-7,S,S,O,2-Adm,H),(9-742,i-Pro,J-8,S,S,O,2-Adm,H),(9-743,i-Pro,J-9,S,S,O,2-Adm,H),(9-744,i-Pro,J-1,S,S,O,5-OH-2-Adm,H),(9-745,i-Pro,J-2,S,S,O,5-OH-2-Adm,H),(9-746,i-Pro,J-3,S,S,O,5-OH-2-Adm,H),(9-747,i-Pro,J-4,S,S,O,5-OH-2-Adm,H),(9-748,i-Pro,J-5,S,S,O,5-OH-2-Adm,H),(9-749,i-Pro,J-6,S,S,O,5-OH-2-Adm,H),(9-750,i-Pro,J-7,S,S,O,5-OH-2-Adm,H),(9-751,i-Pro,J-8,S,S,O,5-OH-2-Adm,H),(9-752,i-Pro,J-9,S,S,O,5-OH-2-Adm,H),(9-753,i-Pro,K-1,S,S,O,1-Adm,H),(9-754,i-Pro,K-2,S,S,O,1-Adm,H),(9-755,i-Pro,K-3,S,S,O,1-Adm,H),(9-756,i-Pro,K-4,S,S,O,1-Adm,H),(9-757,i-Pro,K-5,S,S,O,1-Adm,H),(9-758,i-Pro,K-6,S,S,O,1-Adm,H),(9-759,i-Pro,K-7,S,S,O,1-Adm,H),(9-760,i-Pro,K-8,S,S,O,1-Adm,H),(9-761,i-Pro,K-9,S,S,O,1-Adm,H),(9-762,i-Pro,K-1,S,S,O,2-Adm,H),(9-763,i-Pro,K-2,S,S,O,2-Adm,H),(9-764,i-Pro,K-3,S,S,O,2-Adm,H),(9-765,i-Pro,K-4,S,S,O,2-Adm,H),(9-766,i-Pro,K-5,S,S,O,2-Adm,H),(9-767,i-Pro,K-6,S,S,O,2-Adm,H),(9-768,i-Pro,K-7,S,S,O,2-Adm,H),(9-769,i-Pro,K-8,S,S,O,2-Adm,H),(9-770,i-Pro,K-9,S,S,O,2-Adm,H),(9-771,i-Pro,K-1,S,S,O,5-OH-2-Adm,H),(9-772,i-Pro,K-2,S,S,O,5-OH-2-Adm,H),(9-773,i-Pro,K-3,S,S,O,5-OH-2-Adm,H),(9-774,i-Pro,K-4,S,S,O,5-OH-2-Adm,H),(9-775,i-Pro,K-5,S,S,O,5-OH-2-Adm,H),(9-776,i-Pro,K-6,S,S,O,5-OH-2-Adm,H),(9-777,i-Pro,K-7,S,S,O,5-OH-2-Adm,H),(9-778,i-Pro,K-8,S,S,O,5-OH-2-Adm,H),(9-779,i-Pro,K-9,S,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(10-1,i-Bu,A-1,O,S,O,1-Adm,H),(10-2,i-Bu,A-2,O,S,O,1-Adm,H),(10-3,i-Bu,A-3,O,S,O,1-Adm,H),(10-4,i-Bu,A-4,O,S,O,1-Adm,H),(10-5,i-Bu,A-5,O,S,O,1-Adm,H),(10-6,i-Bu,A-6,O,S,O,1-Adm,H),(10-7,i-Bu,A-7,O,S,O,1-Adm,H),(10-8,i-Bu,A-8,O,S,O,1-Adm,H),(10-9,i-Bu,A-9,O,S,O,1-Adm,H),(10-10,i-Bu,A-10,O,S,O,1-Adm,H),(10-11,i-Bu,A-11,O,S,O,1-Adm,H),(10-12,i-Bu,A-12,O,S,O,1-Adm,H),(10-13,i-Bu,A-13,O,S,O,1-Adm,H),(10-14,i-Bu,A-14,O,S,O,1-Adm,H),(10-15,i-Bu,A-15,O,S,O,1-Adm,H),(10-16,i-Bu,A-16,O,S,O,1-Adm,H),(10-17,i-Bu,A-17,O,S,O,1-Adm,H),(10-18,i-Bu,A-18,O,S,O,1-Adm,H),(10-19,i-Bu,A-19,O,S,O,1-Adm,H),(10-20,i-Bu,A-20,O,S,O,1-Adm,H),(10-21,i-Bu,A-21,O,S,O,1-Adm,H),(10-22,i-Bu,A-22,O,S,O,1-Adm,H),(10-23,i-Bu,A-23,O,S,O,1-Adm,H),(10-24,i-Bu,A-24,O,S,O,1-Adm,H),(10-25,i-Bu,A-25,O,S,O,1-Adm,H),(10-26,i-Bu,A-26,O,S,O,1-Adm,H),(10-27,i-Bu,A-27,O,S,O,1-Adm,H),(10-28,i-Bu,A-28,O,S,O,1-Adm,H),(10-29,i-Bu,A-29,O,S,O,1-Adm,H),(10-30,i-Bu,A-30,O,S,O,1-Adm,H),(10-31,i-Bu,A-31,O,S,O,1-Adm,H),(10-32,i-Bu,A-32,O,S,O,1-Adm,H),(10-33,i-Bu,A-33,O,S,O,1-Adm,H),(10-34,i-Bu,A-34,O,S,O,1-Adm,H),(10-35,i-Bu,A-35,O,S,O,1-Adm,H),(10-36,i-Bu,A-36,O,S,O,1-Adm,H),(10-37,i-Bu,A-1,O,S,O,2-Adm,H),(10-38,i-Bu,A-2,O,S,O,2-Adm,H),(10-39,i-Bu,A-3,O,S,O,2-Adm,H),(10-40,i-Bu,A-4,O,S,O,2-Adm,H),(10-41,i-Bu,A-5,O,S,O,2-Adm,H),(10-42,i-Bu,A-6,O,S,O,2-Adm,H),(10-43,i-Bu,A-7,O,S,O,2-Adm,H),(10-44,i-Bu,A-8,O,S,O,2-Adm,H),(10-45,i-Bu,A-9,O,S,O,2-Adm,H),(10-46,i-Bu,A-10,O,S,O,2-Adm,H),(10-47,i-Bu,A-11,O,S,O,2-Adm,H),(10-48,i-Bu,A-12,O,S,O,2-Adm,H),(10-49,i-Bu,A-13,O,S,O,2-Adm,H),(10-50,i-Bu,A-14,O,S,O,2-Adm,H),(10-51,i-Bu,A-15,O,S,O,2-Adm,H),(10-52,i-Bu,A-16,O,S,O,2-Adm,H),(10-53,i-Bu,A-17,O,S,O,2-Adm,H),(10-54,i-Bu,A-18,O,S,O,2-Adm,H),(10-55,i-Bu,A-19,O,S,O,2-Adm,H),(10-56,i-Bu,A-20,O,S,O,2-Adm,H),(10-57,i-Bu,A-21,O,S,O,2-Adm,H),(10-58,i-Bu,A-22,O,S,O,2-Adm,H),(10-59,i-Bu,A-23,O,S,O,2-Adm,H),(10-60,i-Bu,A-24,O,S,O,2-Adm,H),(10-61,i-Bu,A-25,O,S,O,2-Adm,H),(10-62,i-Bu,A-26,O,S,O,2-Adm,H),(10-63,i-Bu,A-27,O,S,O,2-Adm,H),(10-64,i-Bu,A-28,O,S,O,2-Adm,H),(10-65,i-Bu,A-29,O,S,O,2-Adm,H),(10-66,i-Bu,A-30,O,S,O,2-Adm,H),(10-67,i-Bu,A-31,O,S,O,2-Adm,H),(10-68,i-Bu,A-32,O,S,O,2-Adm,H),(10-69,i-Bu,A-33,O,S,O,2-Adm,H),(10-70,i-Bu,A-34,O,S,O,2-Adm,H),(10-71,i-Bu,A-35,O,S,O,2-Adm,H),(10-72,i-Bu,A-36,O,S,O,2-Adm,H),(10-73,i-Bu,A-1,O,S,O,5-OH-2-Adm,H),(10-74,i-Bu,A-2,O,S,O,5-OH-2-Adm,H),(10-75,i-Bu,A-3,O,S,O,5-OH-2-Adm,H),(10-76,i-Bu,A-4,O,S,O,5-OH-2-Adm,H),(10-77,i-Bu,A-5,O,S,O,5-OH-2-Adm,H),(10-78,i-Bu,A-6,O,S,O,5-OH-2-Adm,H),(10-79,i-Bu,A-7,O,S,O,5-OH-2-Adm,H),(10-80,i-Bu,A-8,O,S,O,5-OH-2-Adm,H),(10-81,i-Bu,A-9,O,S,O,5-OH-2-Adm,H),(10-82,i-Bu,A-10,O,S,O,5-OH-2-Adm,H),(10-83,i-Bu,A-11,O,S,O,5-OH-2-Adm,H),(10-84,i-Bu,A-12,O,S,O,5-OH-2-Adm,H),(10-85,i-Bu,A-13,O,S,O,5-OH-2-Adm,H),(10-86,i-Bu,A-14,O,S,O,5-OH-2-Adm,H),(10-87,i-Bu,A-15,O,S,O,5-OH-2-Adm,H),(10-88,i-Bu,A-16,O,S,O,5-OH-2-Adm,H),(10-89,i-Bu,A-17,O,S,O,5-OH-2-Adm,H),(10-90,i-Bu,A-18,O,S,O,5-OH-2-Adm,H),(10-91,i-Bu,A-19,O,S,O,5-OH-2-Adm,H),(10-92,i-Bu,A-20,O,S,O,5-OH-2-Adm,H),(10-93,i-Bu,A-21,O,S,O,5-OH-2-Adm,H),(10-94,i-Bu,A-22,O,S,O,5-OH-2-Adm,H),(10-95,i-Bu,A-23,O,S,O,5-OH-2-Adm,H),(10-96,i-Bu,A-24,O,S,O,5-OH-2-Adm,H),(10-97,i-Bu,A-25,O,S,O,5-OH-2-Adm,H),(10-98,i-Bu,A-26,O,S,O,5-OH-2-Adm,H),(10-99,i-Bu,A-27,O,S,O,5-OH-2-Adm,H),(10-100,i-Bu,A-28,O,S,O,5-OH-2-Adm,H),(10-101,i-Bu,A-29,O,S,O,5-OH-2-Adm,H),(10-102,i-Bu,A-30,O,S,O,5-OH-2-Adm,H),(10-103,i-Bu,A-31,O,S,O,5-OH-2-Adm,H),(10-104,i-Bu,A-32,O,S,O,5-OH-2-Adm,H),(10-105,i-Bu,A-33,O,S,O,5-OH-2-Adm,H),(10-106,i-Bu,A-34,O,S,O,5-OH-2-Adm,H),(10-107,i-Bu,A-35,O,S,O,5-OH-2-Adm,H),(10-108,i-Bu,A-36,O,S,O,5-OH-2-Adm,H),(10-109,i-Bu,B-1,O,S,O,1-Adm,H),(10-110,i-Bu,B-2,O,S,O,1-Adm,H),(10-111,i-Bu,B-3,O,S,O,1-Adm,H),(10-112,i-Bu,B-4,O,S,O,1-Adm,H),(10-113,i-Bu,B-5,O,S,O,1-Adm,H),(10-114,i-Bu,B-6,O,S,O,1-Adm,H),(10-115,i-Bu,B-7,O,S,O,1-Adm,H),(10-116,i-Bu,B-8,O,S,O,1-Adm,H),(10-117,i-Bu,B-9,O,S,O,1-Adm,H),(10-118,i-Bu,B-10,O,S,O,1-Adm,H),(10-119,i-Bu,B-11,O,S,O,1-Adm,H),(10-120,i-Bu,B-12,O,S,O,1-Adm,H),(10-121,i-Bu,B-13,O,S,O,1-Adm,H),(10-122,i-Bu,B-14,O,S,O,1-Adm,H),(10-123,i-Bu,B-15,O,S,O,1-Adm,H),(10-124,i-Bu,B-16,O,S,O,1-Adm,H),(10-125,i-Bu,B-17,O,S,O,1-Adm,H),(10-126,i-Bu,B-18,O,S,O,1-Adm,H),(10-127,i-Bu,B-19,O,S,O,1-Adm,H),(10-128,i-Bu,B-20,O,S,O,1-Adm,H),(10-129,i-Bu,B-21,O,S,O,1-Adm,H),(10-130,i-Bu,B-22,O,S,O,1-Adm,H),(10-131,i-Bu,B-23,O,S,O,1-Adm,H),(10-132,i-Bu,B-24,O,S,O,1-Adm,H),(10-133,i-Bu,B-25,O,S,O,1-Adm,H),(10-134,i-Bu,B-26,O,S,O,1-Adm,H),(10-135,i-Bu,B-27,O,S,O,1-Adm,H),(10-136,i-Bu,B-28,O,S,O,1-Adm,H),(10-137,i-Bu,B-29,O,S,O,1-Adm,H),(10-138,i-Bu,B-30,O,S,O,1-Adm,H),(10-139,i-Bu,B-31,O,S,O,1-Adm,H),(10-140,i-Bu,B-32,O,S,O,1-Adm,H),(10-141,i-Bu,B-33,O,S,O,1-Adm,H),(10-142,i-Bu,B-34,O,S,O,1-Adm,H),(10-143,i-Bu,B-35,O,S,O,1-Adm,H),(10-144,i-Bu,B-36,O,S,O,1-Adm,H),(10-145,i-Bu,B-1,O,S,O,2-Adm,H),(10-146,i-Bu,B-2,O,S,O,2-Adm,H),(10-147,i-Bu,B-3,O,S,O,2-Adm,H),(10-148,i-Bu,B-4,O,S,O,2-Adm,H),(10-149,i-Bu,B-5,O,S,O,2-Adm,H),(10-150,i-Bu,B-6,O,S,O,2-Adm,H),(10-151,i-Bu,B-7,O,S,O,2-Adm,H),(10-152,i-Bu,B-8,O,S,O,2-Adm,H),(10-153,i-Bu,B-9,O,S,O,2-Adm,H),(10-154,i-Bu,B-10,O,S,O,2-Adm,H),(10-155,i-Bu,B-11,O,S,O,2-Adm,H),(10-156,i-Bu,B-12,O,S,O,2-Adm,H),(10-157,i-Bu,B-13,O,S,O,2-Adm,H),(10-158,i-Bu,B-14,O,S,O,2-Adm,H),(10-159,i-Bu,B-15,O,S,O,2-Adm,H),(10-160,i-Bu,B-16,O,S,O,2-Adm,H),(10-161,i-Bu,B-17,O,S,O,2-Adm,H),(10-162,i-Bu,B-18,O,S,O,2-Adm,H),(10-163,i-Bu,B-19,O,S,O,2-Adm,H),(10-164,i-Bu,B-20,O,S,O,2-Adm,H),(10-165,i-Bu,B-21,O,S,O,2-Adm,H),(10-166,i-Bu,B-22,O,S,O,2-Adm,H),(10-167,i-Bu,B-23,O,S,O,2-Adm,H),(10-168,i-Bu,B-24,O,S,O,2-Adm,H),(10-169,i-Bu,B-25,O,S,O,2-Adm,H),(10-170,i-Bu,B-26,O,S,O,2-Adm,H),(10-171,i-Bu,B-27,O,S,O,2-Adm,H),(10-172,i-Bu,B-28,O,S,O,2-Adm,H),(10-173,i-Bu,B-29,O,S,O,2-Adm,H),(10-174,i-Bu,B-30,O,S,O,2-Adm,H),(10-175,i-Bu,B-31,O,S,O,2-Adm,H),(10-176,i-Bu,B-32,O,S,O,2-Adm,H),(10-177,i-Bu,B-33,O,S,O,2-Adm,H),(10-178,i-Bu,B-34,O,S,O,2-Adm,H),(10-179,i-Bu,B-35,O,S,O,2-Adm,H),(10-180,i-Bu,B-36,O,S,O,2-Adm,H),(10-181,i-Bu,B-1,O,S,O,5-OH-2-Adm,H),(10-182,i-Bu,B-2,O,S,O,5-OH-2-Adm,H),(10-183,i-Bu,B-3,O,S,O,5-OH-2-Adm,H),(10-184,i-Bu,B-4,O,S,O,5-OH-2-Adm,H),(10-185,i-Bu,B-5,O,S,O,5-OH-2-Adm,H),(10-186,i-Bu,B-6,O,S,O,5-OH-2-Adm,H),(10-187,i-Bu,B-7,O,S,O,5-OH-2-Adm,H),(10-188,i-Bu,B-8,O,S,O,5-OH-2-Adm,H),(10-189,i-Bu,B-9,O,S,O,5-OH-2-Adm,H),(10-190,i-Bu,B-10,O,S,O,5-OH-2-Adm,H),(10-191,i-Bu,B-11,O,S,O,5-OH-2-Adm,H),(10-192,i-Bu,B-12,O,S,O,5-OH-2-Adm,H),(10-193,i-Bu,B-13,O,S,O,5-OH-2-Adm,H),(10-194,i-Bu,B-14,O,S,O,5-OH-2-Adm,H),(10-195,i-Bu,B-15,O,S,O,5-OH-2-Adm,H),(10-196,i-Bu,B-16,O,S,O,5-OH-2-Adm,H),(10-197,i-Bu,B-17,O,S,O,5-OH-2-Adm,H),(10-198,i-Bu,B-18,O,S,O,5-OH-2-Adm,H),(10-199,i-Bu,B-19,O,S,O,5-OH-2-Adm,H),(10-200,i-Bu,B-20,O,S,O,5-OH-2-Adm,H),(10-201,i-Bu,B-21,O,S,O,5-OH-2-Adm,H),(10-202,i-Bu,B-22,O,S,O,5-OH-2-Adm,H),(10-203,i-Bu,B-23,O,S,O,5-OH-2-Adm,H),(10-204,i-Bu,B-24,O,S,O,5-OH-2-Adm,H),(10-205,i-Bu,B-25,O,S,O,5-OH-2-Adm,H),(10-206,i-Bu,B-26,O,S,O,5-OH-2-Adm,H),(10-207,i-Bu,B-27,O,S,O,5-OH-2-Adm,H),(10-208,i-Bu,B-28,O,S,O,5-OH-2-Adm,H),(10-209,i-Bu,B-29,O,S,O,5-OH-2-Adm,H),(10-210,i-Bu,B-30,O,S,O,5-OH-2-Adm,H),(10-211,i-Bu,B-31,O,S,O,5-OH-2-Adm,H),(10-212,i-Bu,B-32,O,S,O,5-OH-2-Adm,H),(10-213,i-Bu,B-33,O,S,O,5-OH-2-Adm,H),(10-214,i-Bu,B-34,O,S,O,5-OH-2-Adm,H),(10-215,i-Bu,B-35,O,S,O,5-OH-2-Adm,H),(10-216,i-Bu,B-36,O,S,O,5-OH-2-Adm,H),(10-217,i-Bu,C-1,O,S,O,1-Adm,H),(10-218,i-Bu,C-2,O,S,O,1-Adm,H),(10-219,i-Bu,C-3,O,S,O,1-Adm,H),(10-220,i-Bu,C-4,O,S,O,1-Adm,H),(10-221,i-Bu,C-5,O,S,O,1-Adm,H),(10-222,i-Bu,C-6,O,S,O,1-Adm,H),(10-223,i-Bu,C-7,O,S,O,1-Adm,H),(10-224,i-Bu,C-8,O,S,O,1-Adm,H),(10-225,i-Bu,C-9,O,S,O,1-Adm,H),(10-226,i-Bu,C-10,O,S,O,1-Adm,H),(10-227,i-Bu,C-11,O,S,O,1-Adm,H),(10-228,i-Bu,C-12,O,S,O,1-Adm,H),(10-229,i-Bu,C-13,O,S,O,1-Adm,H),(10-230,i-Bu,C-14,O,S,O,1-Adm,H),(10-231,i-Bu,C-15,O,S,O,1-Adm,H),(10-232,i-Bu,C-16,O,S,O,1-Adm,H),(10-233,i-Bu,C-17,O,S,O,1-Adm,H),(10-234,i-Bu,C-18,O,S,O,1-Adm,H),(10-235,i-Bu,C-19,O,S,O,1-Adm,H),(10-236,i-Bu,C-20,O,S,O,1-Adm,H),(10-237,i-Bu,C-21,O,S,O,1-Adm,H),(10-238,i-Bu,C-22,O,S,O,1-Adm,H),(10-239,i-Bu,C-23,O,S,O,1-Adm,H),(10-240,i-Bu,C-24,O,S,O,1-Adm,H),(10-241,i-Bu,C-25,O,S,O,1-Adm,H),(10-242,i-Bu,C-26,O,S,O,1-Adm,H),(10-243,i-Bu,C-27,O,S,O,1-Adm,H),(10-244,i-Bu,C-28,O,S,O,1-Adm,H),(10-245,i-Bu,C-29,O,S,O,1-Adm,H),(10-246,i-Bu,C-30,O,S,O,1-Adm,H),(10-247,i-Bu,C-31,O,S,O,1-Adm,H),(10-248,i-Bu,C-32,O,S,O,1-Adm,H),(10-249,i-Bu,C-33,O,S,O,1-Adm,H),(10-250,i-Bu,C-34,O,S,O,1-Adm,H),(10-251,i-Bu,C-35,O,S,O,1-Adm,H),(10-252,i-Bu,C-36,O,S,O,1-Adm,H),(10-253,i-Bu,C-1,O,S,O,2-Adm,H),(10-254,i-Bu,C-2,O,S,O,2-Adm,H),(10-255,i-Bu,C-3,O,S,O,2-Adm,H),(10-256,i-Bu,C-4,O,S,O,2-Adm,H),(10-257,i-Bu,C-5,O,S,O,2-Adm,H),(10-258,i-Bu,C-6,O,S,O,2-Adm,H),(10-259,i-Bu,C-7,O,S,O,2-Adm,H),(10-260,i-Bu,C-8,O,S,O,2-Adm,H),(10-261,i-Bu,C-9,O,S,O,2-Adm,H),(10-262,i-Bu,C-10,O,S,O,2-Adm,H),(10-263,i-Bu,C-11,O,S,O,2-Adm,H),(10-264,i-Bu,C-12,O,S,O,2-Adm,H),(10-265,i-Bu,C-13,O,S,O,2-Adm,H),(10-266,i-Bu,C-14,O,S,O,2-Adm,H),(10-267,i-Bu,C-15,O,S,O,2-Adm,H),(10-268,i-Bu,C-16,O,S,O,2-Adm,H),(10-269,i-Bu,C-17,O,S,O,2-Adm,H),(10-270,i-Bu,C-18,O,S,O,2-Adm,H),(10-271,i-Bu,C-19,O,S,O,2-Adm,H),(10-272,i-Bu,C-20,O,S,O,2-Adm,H),(10-273,i-Bu,C-21,O,S,O,2-Adm,H),(10-274,i-Bu,C-22,O,S,O,2-Adm,H),(10-275,i-Bu,C-23,O,S,O,2-Adm,H),(10-276,i-Bu,C-24,O,S,O,2-Adm,H),(10-277,i-Bu,C-25,O,S,O,2-Adm,H),(10-278,i-Bu,C-26,O,S,O,2-Adm,H),(10-279,i-Bu,C-27,O,S,O,2-Adm,H),(10-280,i-Bu,C-28,O,S,O,2-Adm,H),(10-281,i-Bu,C-29,O,S,O,2-Adm,H),(10-282,i-Bu,C-30,O,S,O,2-Adm,H),(10-283,i-Bu,C-31,O,S,O,2-Adm,H),(10-284,i-Bu,C-32,O,S,O,2-Adm,H),(10-285,i-Bu,C-33,O,S,O,2-Adm,H),(10-286,i-Bu,C-34,O,S,O,2-Adm,H),(10-287,i-Bu,C-35,O,S,O,2-Adm,H),(10-288,i-Bu,C-36,O,S,O,2-Adm,H),(10-289,i-Bu,C-1,O,S,O,5-OH-2-Adm,H),(10-290,i-Bu,C-2,O,S,O,5-OH-2-Adm,H),(10-291,i-Bu,C-3,O,S,O,5-OH-2-Adm,H),(10-292,i-Bu,C-4,O,S,O,5-OH-2-Adm,H),(10-293,i-Bu,C-5,O,S,O,5-OH-2-Adm,H),(10-294,i-Bu,C-6,O,S,O,5-OH-2-Adm,H),(10-295,i-Bu,C-7,O,S,O,5-OH-2-Adm,H),(10-296,i-Bu,C-8,O,S,O,5-OH-2-Adm,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(10-587,i-Bu,F-11,O,S,O,2-Adm,H),(10-588,i-Bu,F-12,O,S,O,2-Adm,H),(10-589,i-Bu,F-13,O,S,O,2-Adm,H),(10-590,i-Bu,F-14,O,S,O,2-Adm,H),(10-591,i-Bu,F-15,O,S,O,2-Adm,H),(10-592,i-Bu,F-16,O,S,O,2-Adm,H),(10-593,i-Bu,F-17,O,S,O,2-Adm,H),(10-594,i-Bu,F-18,O,S,O,2-Adm,H),(10-595,i-Bu,F-19,O,S,O,2-Adm,H),(10-596,i-Bu,F-20,O,S,O,2-Adm,H),(10-597,i-Bu,F-21,O,S,O,2-Adm,H),(10-598,i-Bu,F-22,O,S,O,2-Adm,H),(10-599,i-Bu,F-23,O,S,O,2-Adm,H),(10-600,i-Bu,F-24,O,S,O,2-Adm,H),(10-601,i-Bu,F-25,O,S,O,2-Adm,H),(10-602,i-Bu,F-26,O,S,O,2-Adm,H),(10-603,i-Bu,F-27,O,S,O,2-Adm,H),(10-604,i-Bu,F-28,O,S,O,2-Adm,H),(10-605,i-Bu,F-29,O,S,O,2-Adm,H),(10-606,i-Bu,F-30,O,S,O,2-Adm,H),(10-607,i-Bu,F-31,O,S,O,2-Adm,H),(10-608,i-Bu,F-32,O,S,O,2-Adm,H),(10-609,i-Bu,F-33,O,S,O,2-Adm,H),(10-610,i-Bu,F-34,O,S,O,2-Adm,H),(10-611,i-Bu,F-35,O,S,O,2-Adm,H),(10-612,i-Bu,F-36,O,S,O,2-Adm,H),(10-613,i-Bu,F-1,O,S,O,5-OH-2-Adm,H),(10-614,i-Bu,F-2,O,S,O,5-OH-2-Adm,H),(10-615,i-Bu,F-3,O,S,O,5-OH-2-Adm,H),(10-616,i-Bu,F-4,O,S,O,5-OH-2-Adm,H),(10-617,i-Bu,F-5,O,S,O,5-OH-2-Adm,H),(10-618,i-Bu,F-6,O,S,O,5-OH-2-Adm,H),(10-619,i-Bu,F-7,O,S,O,5-OH-2-Adm,H),(10-620,i-Bu,F-8,O,S,O,5-OH-2-Adm,H),(10-621,i-Bu,F-9,O,S,O,5-OH-2-Adm,H),(10-622,i-Bu,F-10,O,S,O,5-OH-2-Adm,H),(10-623,i-Bu,F-11,O,S,O,5-OH-2-Adm,H),(10-624,i-Bu,F-12,O,S,O,5-OH-2-Adm,H),(10-625,i-Bu,F-13,O,S,O,5-OH-2-Adm,H),(10-626,i-Bu,F-14,O,S,O,5-OH-2-Adm,H),(10-627,i-Bu,F-15,O,S,O,5-OH-2-Adm,H),(10-628,i-Bu,F-16,O,S,O,5-OH-2-Adm,H),(10-629,i-Bu,F-17,O,S,O,5-OH-2-Adm,H),(10-630,i-Bu,F-18,O,S,O,5-OH-2-Adm,H),(10-631,i-Bu,F-19,O,S,O,5-OH-2-Adm,H),(10-632,i-Bu,F-20,O,S,O,5-OH-2-Adm,H),(10-633,i-Bu,F-21,O,S,O,5-OH-2-Adm,H),(10-634,i-Bu,F-22,O,S,O,5-OH-2-Adm,H),(10-635,i-Bu,F-23,O,S,O,5-OH-2-Adm,H),(10-636,i-Bu,F-24,O,S,O,5-OH-2-Adm,H),(10-637,i-Bu,F-25,O,S,O,5-OH-2-Adm,H),(10-638,i-Bu,F-26,O,S,O,5-OH-2-Adm,H),(10-639,i-Bu,F-27,O,S,O,5-OH-2-Adm,H),(10-640,i-Bu,F-28,O,S,O,5-OH-2-Adm,H),(10-641,i-Bu,F-29,O,S,O,5-OH-2-Adm,H),(10-642,i-Bu,F-30,O,S,O,5-OH-2-Adm,H),(10-643,i-Bu,F-31,O,S,O,5-OH-2-Adm,H),(10-644,i-Bu,F-32,O,S,O,5-OH-2-Adm,H),(10-645,i-Bu,F-33,O,S,O,5-OH-2-Adm,H),(10-646,i-Bu,F-34,O,S,O,5-OH-2-Adm,H),(10-647,i-Bu,F-35,O,S,O,5-OH-2-Adm,H),(10-648,i-Bu,F-36,O,S,O,5-OH-2-Adm,H),(10-649,i-Bu,G-1,O,S,O,1-Adm,H),(10-650,i-Bu,G-2,O,S,O,1-Adm,H),(10-651,i-Bu,G-3,O,S,O,1-Adm,H),(10-652,i-Bu,G-4,O,S,O,1-Adm,H),(10-653,i-Bu,G-5,O,S,O,1-Adm,H),(10-654,i-Bu,G-6,O,S,O,1-Adm,H),(10-655,i-Bu,G-7,O,S,O,1-Adm,H),(10-656,i-Bu,G-8,O,S,O,1-Adm,H),(10-657,i-Bu,G-9,O,S,O,1-Adm,H),(10-658,i-Bu,G-1,O,S,O,2-Adm,H),(10-659,i-Bu,G-2,O,S,O,2-Adm,H),(10-660,i-Bu,G-3,O,S,O,2-Adm,H),(10-661,i-Bu,G-4,O,S,O,2-Adm,H),(10-662,i-Bu,G-5,O,S,O,2-Adm,H),(10-663,i-Bu,G-6,O,S,O,2-Adm,H),(10-664,i-Bu,G-7,O,S,O,2-Adm,H),(10-665,i-Bu,G-8,O,S,O,2-Adm,H),(10-666,i-Bu,G-9,O,S,O,2-Adm,H),(10-667,i-Bu,G-1,O,S,O,5-OH-2-Adm,H),(10-668,i-Bu,G-2,O,S,O,5-OH-2-Adm,H),(10-669,i-Bu,G-3,O,S,O,5-OH-2-Adm,H),(10-670,i-Bu,G-4,O,S,O,5-OH-2-Adm,H),(10-671,i-Bu,G-5,O,S,O,5-OH-2-Adm,H),(10-672,i-Bu,G-6,O,S,O,5-OH-2-Adm,H),(10-673,i-Bu,G-7,O,S,O,5-OH-2-Adm,H),(10-674,i-Bu,G-8,O,S,O,5-OH-2-Adm,H),(10-675,i-Bu,G-9,O,S,O,5-OH-2-Adm,H),(10-676,i-Bu,H-1,O,S,O,1-Adm,H),(10-677,i-Bu,H-2,O,S,O,1-Adm,H),(10-678,i-Bu,H-3,O,S,O,1-Adm,H),(10-679,i-Bu,H-4,O,S,O,1-Adm,H),(10-680,i-Bu,H-5,O,S,O,1-Adm,H),(10-681,i-Bu,H-6,O,S,O,1-Adm,H),(10-682,i-Bu,H-7,O,S,O,1-Adm,H),(10-683,i-Bu,H-8,O,S,O,1-Adm,H),(10-684,i-Bu,H-9,O,S,O,1-Adm,H),(10-685,i-Bu,H-1,O,S,O,2-Adm,H),(10-686,i-Bu,H-2,O,S,O,2-Adm,H),(10-687,i-Bu,H-3,O,S,O,2-Adm,H),(10-688,i-Bu,H-4,O,S,O,2-Adm,H),(10-689,i-Bu,H-5,O,S,O,2-Adm,H),(10-690,i-Bu,H-6,O,S,O,2-Adm,H),(10-691,i-Bu,H-7,O,S,O,2-Adm,H),(10-692,i-Bu,H-8,O,S,O,2-Adm,H),(10-693,i-Bu,H-9,O,S,O,2-Adm,H),(10-694,i-Bu,H-1,O,S,O,5-OH-2-Adm,H),(10-695,i-Bu,H-2,O,S,O,5-OH-2-Adm,H),(10-696,i-Bu,H-3,O,S,O,5-OH-2-Adm,H),(10-697,i-Bu,H-4,O,S,O,5-OH-2-Adm,H),(10-698,i-Bu,H-5,O,S,O,5-OH-2-Adm,H),(10-699,i-Bu,H-6,O,S,O,5-OH-2-Adm,H),(10-700,i-Bu,H-7,O,S,O,5-OH-2-Adm,H),(10-701,i-Bu,H-8,O,S,O,5-OH-2-Adm,H),(10-702,i-Bu,H-9,O,S,O,5-OH-2-Adm,H),(10-703,i-Bu,I-1,O,S,O,1-Adm,H),(10-704,i-Bu,I-2,O,S,O,1-Adm,H),(10-705,i-Bu,I-3,O,S,O,1-Adm,H),(10-706,i-Bu,I-4,O,S,O,1-Adm,H),(10-707,i-Bu,I-5,O,S,O,1-Adm,H),(10-708,i-Bu,I-6,O,S,O,1-Adm,H),(10-709,i-Bu,I-7,O,S,O,1-Adm,H),(10-710,i-Bu,I-8,O,S,O,1-Adm,H),(10-711,i-Bu,I-9,O,S,O,1-Adm,H),(10-712,i-Bu,I-1,O,S,O,2-Adm,H),(10-713,i-Bu,I-2,O,S,O,2-Adm,H),(10-714,i-Bu,I-3,O,S,O,2-Adm,H),(10-715,i-Bu,I-4,O,S,O,2-Adm,H),(10-716,i-Bu,I-5,O,S,O,2-Adm,H),(10-717,i-Bu,I-6,O,S,O,2-Adm,H),(10-718,i-Bu,I-7,O,S,O,2-Adm,H),(10-719,i-Bu,I-8,O,S,O,2-Adm,H),(10-720,i-Bu,I-9,O,S,O,2-Adm,H),(10-721,i-Bu,I-1,O,S,O,5-OH-2-Adm,H),(10-722,i-Bu,I-2,O,S,O,5-OH-2-Adm,H),(10-723,i-Bu,I-3,O,S,O,5-OH-2-Adm,H),(10-724,i-Bu,I-4,O,S,O,5-OH-2-Adm,H),(10-725,i-Bu,I-5,O,S,O,5-OH-2-Adm,H),(10-726,i-Bu,I-6,O,S,O,5-OH-2-Adm,H),(10-727,i-Bu,I-7,O,S,O,5-OH-2-Adm,H),(10-728,i-Bu,I-8,O,S,O,5-OH-2-Adm,H),(10-729,i-Bu,I-9,O,S,O,5-OH-2-Adm,H),(10-730,i-Bu,J-1,O,S,O,1-Adm,H),(10-731,i-Bu,J-2,O,S,O,1-Adm,H),(10-732,i-Bu,J-3,O,S,O,1-Adm,H),(10-733,i-Bu,J-4,O,S,O,1-Adm,H),(10-734,i-Bu,J-5,O,S,O,1-Adm,H),(10-735,i-Bu,J-6,O,S,O,1-Adm,H),(10-736,i-Bu,J-7,O,S,O,1-Adm,H),(10-737,i-Bu,J-8,O,S,O,1-Adm,H),(10-738,i-Bu,J-9,O,S,O,1-Adm,H),(10-739,i-Bu,J-1,O,S,O,2-Adm,H),(10-740,i-Bu,J-2,O,S,O,2-Adm,H),(10-741,i-Bu,J-3,O,S,O,2-Adm,H),(10-742,i-Bu,J-4,O,S,O,2-Adm,H),(10-743,i-Bu,J-5,O,S,O,2-Adm,H),(10-744,i-Bu,J-6,O,S,O,2-Adm,H),(10-745,i-Bu,J-7,O,S,O,2-Adm,H),(10-746,i-Bu,J-8,O,S,O,2-Adm,H),(10-747,i-Bu,J-9,O,S,O,2-Adm,H),(10-748,i-Bu,J-1,O,S,O,5-OH-2-Adm,H),(10-749,i-Bu,J-2,O,S,O,5-OH-2-Adm,H),(10-750,i-Bu,J-3,O,S,O,5-OH-2-Adm,H),(10-751,i-Bu,J-4,O,S,O,5-OH-2-Adm,H),(10-752,i-Bu,J-5,O,S,O,5-OH-2-Adm,H),(10-753,i-Bu,J-6,O,S,O,5-OH-2-Adm,H),(10-754,i-Bu,J-7,O,S,O,5-OH-2-Adm,H),(10-755,i-Bu,J-8,O,S,O,5-OH-2-Adm,H),(10-756,i-Bu,J-9,O,S,O,5-OH-2-Adm,H),(10-757,i-Bu,K-1,O,S,O,1-Adm,H),(10-758,i-Bu,K-2,O,S,O,1-Adm,H),(10-759,i-Bu,K-3,O,S,O,1-Adm,H),(10-760,i-Bu,K-4,O,S,O,1-Adm,H),(10-761,i-Bu,K-5,O,S,O,1-Adm,H),(10-762,i-Bu,K-6,O,S,O,1-Adm,H),(10-763,i-Bu,K-7,O,S,O,1-Adm,H),(10-764,i-Bu,K-8,O,S,O,1-Adm,H),(10-765,i-Bu,K-9,O,S,O,1-Adm,H),(10-766,i-Bu,K-1,O,S,O,2-Adm,H),(10-767,i-Bu,K-2,O,S,O,2-Adm,H),(10-768,i-Bu,K-3,O,S,O,2-Adm,H),(10-769,i-Bu,K-4,O,S,O,2-Adm,H),(10-770,i-Bu,K-5,O,S,O,2-Adm,H),(10-771,i-Bu,K-6,O,S,O,2-Adm,H),(10-772,i-Bu,K-7,O,S,O,2-Adm,H),(10-773,i-Bu,K-8,O,S,O,2-Adm,H),(10-774,i-Bu,K-9,O,S,O,2-Adm,H),(10-775,i-Bu,K-1,O,S,O,5-OH-2-Adm,H),(10-776,i-Bu,K-2,O,S,O,5-OH-2-Adm,H),(10-777,i-Bu,K-3,O,S,O,5-OH-2-Adm,H),(10-778,i-Bu,K-4,O,S,O,5-OH-2-Adm,H),(10-779,i-Bu,K-5,O,S,O,5-OH-2-Adm,H),(10-780,i-Bu,K-6,O,S,O,5-OH-2-Adm,H),(10-781,i-Bu,K-7,O,S,O,5-OH-2-Adm,H),(10-782,i-Bu,K-8,O,S,O,5-OH-2-Adm,H),(10-783,i-Bu,K-9,O,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(11-1,Bu,A-1,O,S,O,1-Adm,H),(11-2,Bu,A-2,O,S,O,1-Adm,H),(11-3,Bu,A-3,O,S,O,1-Adm,H),(11-4,Bu,A-4,O,S,O,1-Adm,H),(11-5,Bu,A-5,O,S,O,1-Adm,H),(11-6,Bu,A-6,O,S,O,1-Adm,H),(11-7,Bu,A-7,O,S,O,1-Adm,H),(11-8,Bu,A-8,O,S,O,1-Adm,H),(11-9,Bu,A-9,O,S,O,1-Adm,H),(11-10,Bu,A-10,O,S,O,1-Adm,H),(11-11,Bu,A-11,O,S,O,1-Adm,H),(11-12,Bu,A-12,O,S,O,1-Adm,H),(11-13,Bu,A-13,O,S,O,1-Adm,H),(11-14,Bu,A-14,O,S,O,1-Adm,H),(11-15,Bu,A-15,O,S,O,1-Adm,H),(11-16,Bu,A-16,O,S,O,1-Adm,H),(11-17,Bu,A-17,O,S,O,1-Adm,H),(11-18,Bu,A-18,O,S,O,1-Adm,H),(11-19,Bu,A-19,O,S,O,1-Adm,H),(11-20,Bu,A-20,O,S,O,1-Adm,H),(11-21,Bu,A-21,O,S,O,1-Adm,H),(11-22,Bu,A-22,O,S,O,1-Adm,H),(11-23,Bu,A-23,O,S,O,1-Adm,H),(11-24,Bu,A-24,O,S,O,1-Adm,H),(11-25,Bu,A-25,O,S,O,1-Adm,H),(11-26,Bu,A-26,O,S,O,1-Adm,H),(11-27,Bu,A-27,O,S,O,1-Adm,H),(11-28,Bu,A-28,O,S,O,1-Adm,H),(11-29,Bu,A-29,O,S,O,1-Adm,H),(11-30,Bu,A-30,O,S,O,1-Adm,H),(11-31,Bu,A-31,O,S,O,1-Adm,H),(11-32,Bu,A-32,O,S,O,1-Adm,H),(11-33,Bu,A-33,O,S,O,1-Adm,H),(11-34,Bu,A-34,O,S,O,1-Adm,H),(11-35,Bu,A-35,O,S,O,1-Adm,H),(11-36,Bu,A-36,O,S,O,1-Adm,H),(11-37,Bu,A-1,O,S,O,2-Adm,H),(11-38,Bu,A-2,O,S,O,2-Adm,H),(11-39,Bu,A-3,O,S,O,2-Adm,H),(11-40,Bu,A-4,O,S,O,2-Adm,H),(11-41,Bu,A-5,O,S,O,2-Adm,H),(11-42,Bu,A-6,O,S,O,2-Adm,H),(11-43,Bu,A-7,O,S,O,2-Adm,H),(11-44,Bu,A-8,O,S,O,2-Adm,H),(11-45,Bu,A-9,O,S,O,2-Adm,H),(11-46,Bu,A-11,O,S,O,2-Adm,H),(11-47,Bu,A-11,O,S,O,2-Adm,H),(11-48,Bu,A-12,O,S,O,2-Adm,H),(11-49,Bu,A-13,O,S,O,2-Adm,H),(11-50,Bu,A-14,O,S,O,2-Adm,H),(11-51,Bu,A-15,O,S,O,2-Adm,H),(11-52,Bu,A-16,O,S,O,2-Adm,H),(11-53,Bu,A-17,O,S,O,2-Adm,H),(11-54,Bu,A-18,O,S,O,2-Adm,H),(11-55,Bu,A-19,O,S,O,2-Adm,H),(11-56,Bu,A-20,O,S,O,2-Adm,H),(11-57,Bu,A-21,O,S,O,2-Adm,H),(11-58,Bu,A-22,O,S,O,2-Adm,H),(11-59,Bu,A-23,O,S,O,2-Adm,H),(11-60,Bu,A-24,O,S,O,2-Adm,H),(11-61,Bu,A-25,O,S,O,2-Adm,H),(11-62,Bu,A-26,O,S,O,2-Adm,H),(11-63,Bu,A-27,O,S,O,2-Adm,H),(11-64,Bu,A-28,O,S,O,2-Adm,H),(11-65,Bu,A-29,O,S,O,2-Adm,H),(11-66,Bu,A-30,O,S,O,2-Adm,H),(11-67,Bu,A-31,O,S,O,2-Adm,H),(11-68,Bu,A-32,O,S,O,2-Adm,H),(11-69,Bu,A-33,O,S,O,2-Adm,H),(11-70,Bu,A-34,O,S,O,2-Adm,H),(11-71,Bu,A-35,O,S,O,2-Adm,H),(11-72,Bu,A-36,O,S,O,2-Adm,H),(11-73,Bu,A-1,O,S,O,5-OH-2-Adm,H),(11-74,Bu,A-2,O,S,O,5-OH-2-Adm,H),(11-75,Bu,A-3,O,S,O,5-OH-2-Adm,H),(11-76,Bu,A-4,O,S,O,5-OH-2-Adm,H),(11-77,Bu,A-5,O,S,O,5-OH-2-Adm,H),(11-78,Bu,A-6,O,S,O,5-OH-2-Adm,H),(11-79,Bu,A-7,O,S,O,5-OH-2-Adm,H),(11-80,Bu,A-8,O,S,O,5-OH-2-Adm,H),(11-81,Bu,A-9,O,S,O,5-OH-2-Adm,H),(11-82,Bu,A-10,O,S,O,5-OH-2-Adm,H),(11-83,Bu,A-11,O,S,O,5-OH-2-Adm,H),(11-84,Bu,A-12,O,S,O,5-OH-2-Adm,H),(11-85,Bu,A-13,O,S,O,5-OH-2-Adm,H),(11-86,Bu,A-14,O,S,O,5-OH-2-Adm,H),(11-87,Bu,A-15,O,S,O,5-OH-2-Adm,H),(11-88,Bu,A-16,O,S,O,5-OH-2-Adm,H),(11-89,Bu,A-17,O,S,O,5-OH-2-Adm,H),(11-90,Bu,A-18,O,S,O,5-OH-2-Adm,H),(11-91,Bu,A-19,O,S,O,5-OH-2-Adm,H),(11-92,Bu,A-20,O,S,O,5-OH-2-Adm,H),(11-93,Bu,A-21,O,S,O,5-OH-2-Adm,H),(11-94,Bu,A-22,O,S,O,5-OH-2-Adm,H),(11-95,Bu,A-23,O,S,O,5-OH-2-Adm,H),(11-96,Bu,A-24,O,S,O,5-OH-2-Adm,H),(11-97,Bu,A-25,O,S,O,5-OH-2-Adm,H),(11-98,Bu,A-26,O,S,O,5-OH-2-Adm,H),(11-99,Bu,A-27,O,S,O,5-OH-2-Adm,H),(11-100,Bu,A-28,O,S,O,5-OH-2-Adm,H),(11-101,Bu,A-29,O,S,O,5-OH-2-Adm,H),(11-102,Bu,A-30,O,S,O,5-OH-2-Adm,H),(11-103,Bu,A-31,O,S,O,5-OH-2-Adm,H),(11-104,Bu,A-32,O,S,O,5-OH-2-Adm,H),(11-105,Bu,A-33,O,S,O,5-OH-2-Adm,H),(11-106,Bu,A-34,O,S,O,5-OH-2-Adm,H),(11-107,Bu,A-35,O,S,O,5-OH-2-Adm,H),(11-108,Bu,A-36,O,S,O,5-OH-2-Adm,H),(11-109,Bu,B-1,O,S,O,1-Adm,H),(11-110,Bu,B-2,O,S,O,1-Adm,H),(11-111,Bu,B-3,O,S,O,1-Adm,H),(11-112,Bu,B-4,O,S,O,1-Adm,H),(11-113,Bu,B-5,O,S,O,1-Adm,H),(11-114,Bu,B-6,O,S,O,1-Adm,H),(11-115,Bu,B-7,O,S,O,1-Adm,H),(11-116,Bu,B-8,O,S,O,1-Adm,H),(11-117,Bu,B-9,O,S,O,1-Adm,H),(11-118,Bu,B-10,O,S,O,1-Adm,H),(11-119,Bu,B-11,O,S,O,1-Adm,H),(11-120,Bu,B-12,O,S,O,1-Adm,H),(11-121,Bu,B-13,O,S,O,1-Adm,H),(11-122,Bu,B-14,O,S,O,1-Adm,H),(11-123,Bu,B-15,O,S,O,1-Adm,H),(11-124,Bu,B-16,O,S,O,1-Adm,H),(11-125,Bu,B-17,O,S,O,1-Adm,H),(11-126,Bu,B-18,O,S,O,1-Adm,H),(11-127,Bu,B-19,O,S,O,1-Adm,H),(11-128,Bu,B-20,O,S,O,1-Adm,H),(11-129,Bu,B-21,O,S,O,1-Adm,H),(11-130,Bu,B-22,O,S,O,1-Adm,H),(11-131,Bu,B-23,O,S,O,1-Adm,H),(11-132,Bu,B-24,O,S,O,1-Adm,H),(11-133,Bu,B-25,O,S,O,1-Adm,H),(11-134,Bu,B-26,O,S,O,1-Adm,H),(11-135,Bu,B-27,O,S,O,1-Adm,H),(11-136,Bu,B-28,O,S,O,1-Adm,H),(11-137,Bu,B-29,O,S,O,1-Adm,H),(11-138,Bu,B-30,O,S,O,1-Adm,H),(11-139,Bu,B-31,O,S,O,1-Adm,H),(11-140,Bu,B-32,O,S,O,1-Adm,H),(11-141,Bu,B-33,O,S,O,1-Adm,H),(11-142,Bu,B-34,O,S,O,1-Adm,H),(11-143,Bu,B-35,O,S,O,1-Adm,H),(11-144,Bu,B-36,O,S,O,1-Adm,H),(11-145,Bu,B-1,O,S,O,2-Adm,H),(11-146,Bu,B-2,O,S,O,2-Adm,H),(11-147,Bu,B-3,O,S,O,2-Adm,H),(11-148,Bu,B-4,O,S,O,2-Adm,H),(11-149,Bu,B-5,O,S,O,2-Adm,H),(11-150,Bu,B-6,O,S,O,2-Adm,H),(11-151,Bu,B-7,O,S,O,2-Adm,H),(11-152,Bu,B-8,O,S,O,2-Adm,H),(11-153,Bu,B-9,O,S,O,2-Adm,H),(11-154,Bu,B-10,O,S,O,2-Adm,H),(11-155,Bu,B-11,O,S,O,2-Adm,H),(11-156,Bu,B-12,O,S,O,2-Adm,H),(11-157,Bu,B-13,O,S,O,2-Adm,H),(11-158,Bu,B-14,O,S,O,2-Adm,H),(11-159,Bu,B-15,O,S,O,2-Adm,H),(11-160,Bu,B-16,O,S,O,2-Adm,H),(11-161,Bu,B-17,O,S,O,2-Adm,H),(11-162,Bu,B-18,O,S,O,2-Adm,H),(11-163,Bu,B-19,O,S,O,2-Adm,H),(11-164,Bu,B-20,O,S,O,2-Adm,H),(11-165,Bu,B-21,O,S,O,2-Adm,H),(11-166,Bu,B-22,O,S,O,2-Adm,H),(11-167,Bu,B-23,O,S,O,2-Adm,H),(11-168,Bu,B-24,O,S,O,2-Adm,H),(11-169,Bu,B-25,O,S,O,2-Adm,H),(11-170,Bu,B-26,O,S,O,2-Adm,H),(11-171,Bu,B-27,O,S,O,2-Adm,H),(11-172,Bu,B-28,O,S,O,2-Adm,H),(11-173,Bu,B-29,O,S,O,2-Adm,H),(11-174,Bu,B-30,O,S,O,2-Adm,H),(11-175,Bu,B-31,O,S,O,2-Adm,H),(11-176,Bu,B-32,O,S,O,2-Adm,H),(11-177,Bu,B-33,O,S,O,2-Adm,H),(11-178,Bu,B-34,O,S,O,2-Adm,H),(11-179,Bu,B-35,O,S,O,2-Adm,H),(11-180,Bu,B-36,O,S,O,2-Adm,H),(11-181,Bu,B-1,O,S,O,5-OH-2-Adm,H),(11-182,Bu,B-2,O,S,O,5-OH-2-Adm,H),(11-183,Bu,B-3,O,S,O,5-OH-2-Adm,H),(11-184,Bu,B-4,O,S,O,5-OH-2-Adm,H),(11-185,Bu,B-5,O,S,O,5-OH-2-Adm,H),(11-186,Bu,B-6,O,S,O,5-OH-2-Adm,H),(11-187,Bu,B-7,O,S,O,5-OH-2-Adm,H),(11-188,Bu,B-8,O,S,O,5-OH-2-Adm,H),(11-189,Bu,B-9,O,S,O,5-OH-2-Adm,H),(11-190,Bu,B-10,O,S,O,5-OH-2-Adm,H),(11-191,Bu,B-11,O,S,O,5-OH-2-Adm,H),(11-192,Bu,B-12,O,S,O,5-OH-2-Adm,H),(11-193,Bu,B-13,O,S,O,5-OH-2-Adm,H),(11-194,Bu,B-14,O,S,O,5-OH-2-Adm,H),(11-195,Bu,B-15,O,S,O,5-OH-2-Adm,H),(11-196,Bu,B-16,O,S,O,5-OH-2-Adm,H),(11-197,Bu,B-17,O,S,O,5-OH-2-Adm,H),(11-198,Bu,B-18,O,S,O,5-OH-2-Adm,H),(11-199,Bu,B-19,O,S,O,5-OH-2-Adm,H),(11-200,Bu,B-20,O,S,O,5-OH-2-Adm,H),(11-201,Bu,B-21,O,S,O,5-OH-2-Adm,H),(11-202,Bu,B-22,O,S,O,5-OH-2-Adm,H),(11-203,Bu,B-23,O,S,O,5-OH-2-Adm,H),(11-204,Bu,B-24,O,S,O,5-OH-2-Adm,H),(11-205,Bu,B-25,O,S,O,5-OH-2-Adm,H),(11-206,Bu,B-26,O,S,O,5-OH-2-Adm,H),(11-207,Bu,B-27,O,S,O,5-OH-2-Adm,H),(11-208,Bu,B-28,O,S,O,5-OH-2-Adm,H),(11-209,Bu,B-29,O,S,O,5-OH-2-Adm,H),(11-210,Bu,B-30,O,S,O,5-OH-2-Adm,H),(11-211,Bu,B-31,O,S,O,5-OH-2-Adm,H),(11-212,Bu,B-32,O,S,O,5-OH-2-Adm,H),(11-213,Bu,B-33,O,S,O,5-OH-2-Adm,H),(11-214,Bu,B-34,O,S,O,5-OH-2-Adm,H),(11-215,Bu,B-35,O,S,O,5-OH-2-Adm,H),(11-216,Bu,B-36,O,S,O,5-OH-2-Adm,H),(11-217,Bu,C-1,O,S,O,1-Adm,H),(11-218,Bu,C-2,O,S,O,1-Adm,H),(11-219,Bu,C-3,O,S,O,1-Adm,H),(11-220,Bu,C-4,O,S,O,1-Adm,H),(11-221,Bu,C-5,O,S,O,1-Adm,H),(11-222,Bu,C-6,O,S,O,1-Adm,H),(11-223,Bu,C-7,O,S,O,1-Adm,H),(11-224,Bu,C-8,O,S,O,1-Adm,H),(11-225,Bu,C-9,O,S,O,1-Adm,H),(11-226,Bu,C-10,O,S,O,1-Adm,H),(11-227,Bu,C-11,O,S,O,1-Adm,H),(11-228,Bu,C-12,O,S,O,1-Adm,H),(11-229,Bu,C-13,O,S,O,1-Adm,H),(11-230,Bu,C-14,O,S,O,1-Adm,H),(11-231,Bu,C-15,O,S,O,1-Adm,H),(11-232,Bu,C-16,O,S,O,1-Adm,H),(11-233,Bu,C-17,O,S,O,1-Adm,H),(11-234,Bu,C-18,O,S,O,1-Adm,H),(11-235,Bu,C-19,O,S,O,1-Adm,H),(11-236,Bu,C-20,O,S,O,1-Adm,H),(11-237,Bu,C-21,O,S,O,1-Adm,H),(11-238,Bu,C-22,O,S,O,1-Adm,H),(11-239,Bu,C-23,O,S,O,1-Adm,H),(11-240,Bu,C-24,O,S,O,1-Adm,H),(11-241,Bu,C-25,O,S,O,1-Adm,H),(11-242,Bu,C-26,O,S,O,1-Adm,H),(11-243,Bu,C-27,O,S,O,1-Adm,H),(11-244,Bu,C-28,O,S,O,1-Adm,H),(11-245,Bu,C-29,O,S,O,1-Adm,H),(11-246,Bu,C-30,O,S,O,1-Adm,H),(11-247,Bu,C-31,O,S,O,1-Adm,H),(11-248,Bu,C-32,O,S,O,1-Adm,H),(11-249,Bu,C-33,O,S,O,1-Adm,H),(11-250,Bu,C-34,O,S,O,1-Adm,H),(11-251,Bu,C-35,O,S,O,1-Adm,H),(11-252,Bu,C-36,O,S,O,1-Adm,H),(11-253,Bu,C-1,O,S,O,2-Adm,H),(11-254,Bu,C-2,O,S,O,2-Adm,H),(11-255,Bu,C-3,O,S,O,2-Adm,H),(11-256,Bu,C-4,O,S,O,2-Adm,H),(11-257,Bu,C-5,O,S,O,2-Adm,H),(11-258,Bu,C-6,O,S,O,2-Adm,H),(11-259,Bu,C-7,O,S,O,2-Adm,H),(11-260,Bu,C-8,O,S,O,2-Adm,H),(11-261,Bu,C-9,O,S,O,2-Adm,H),(11-262,Bu,C-10,O,S,O,2-Adm,H),(11-263,Bu,C-11,O,S,O,2-Adm,H),(11-264,Bu,C-12,O,S,O,2-Adm,H),(11-265,Bu,C-13,O,S,O,2-Adm,H),(11-266,Bu,C-14,O,S,O,2-Adm,H),(11-267,Bu,C-15,O,S,O,2-Adm,H),(11-268,Bu,C-16,O,S,O,2-Adm,H),(11-269,Bu,C-17,O,S,O,2-Adm,H),(11-270,Bu,C-18,O,S,O,2-Adm,H),(11-271,Bu,C-19,O,S,O,2-Adm,H),(11-272,Bu,C-20,O,S,O,2-Adm,H),(11-273,Bu,C-21,O,S,O,2-Adm,H),(11-274,Bu,C-22,O,S,O,2-Adm,H),(11-275,Bu,C-23,O,S,O,2-Adm,H),(11-276,Bu,C-24,O,S,O,2-Adm,H),(11-277,Bu,C-25,O,S,O,2-Adm,H),(11-278,Bu,C-26,O,S,O,2-Adm,H),(11-279,Bu,C-27,O,S,O,2-Adm,H),(11-280,Bu,C-28,O,S,O,2-Adm,H),(11-281,Bu,C-29,O,S,O,2-Adm,H),(11-282,Bu,C-30,O,S,O,2-Adm,H),(11-283,Bu,C-31,O,S,O,2-Adm,H),(11-284,Bu,C-32,O,S,O,2-Adm,H),(11-285,Bu,C-33,O,S,O,2-Adm,H),(11-286,Bu,C-34,O,S,O,2-Adm,H),(11-287,Bu,C-35,O,S,O,2-Adm,H),(11-288,Bu,C-36,O,S,O,2-Adm,H),(11-289,Bu,C-1,O,S,O,5-OH-2-Adm,H),(11-290,Bu,C-2,O,S,O,5-OH-2-Adm,H),(11-291,Bu,C-3,O,S,O,5-OH-2-Adm,H),(11-292,Bu,C-4,O,S,O,5-OH-2-Adm,H),(11-293,Bu,C-5,O,S,O,5-OH-2-Adm,H),(11-294,Bu,C-6,O,S,O,5-OH-2-Adm,H),(11-295,Bu,C-7,O,S,O,5-OH-2-Adm,H),(11-296,Bu,C-8,O,S,O,5-OH-2-Adm,H),(11-297,Bu,C-9,O,S,O,5-OH-2-Adm,H),(11-298,Bu,C-10,O,S,O,5-OH-2-Adm,H),(11-299,Bu,C-11,O,S,O,5-OH-2-Adm,H),(11-300,Bu,C-12,O,S,O,5-OH-2-Adm,H),(11-301,Bu,C-13,O,S,O,5-OH-2-Adm,H),(11-302,Bu,C-14,O,S,O,5-OH-2-Adm,H),(11-303,Bu,C-15,O,S,O,5-OH-2-Adm,H),(11-304,Bu,C-16,O,S,O,5-OH-2-Adm,H),(11-305,Bu,C-17,O,S,O,5-OH-2-Adm,H),(11-306,Bu,C-18,O,S,O,5-OH-2-Adm,H),(11-307,Bu,C-19,O,S,O,5-OH-2-Adm,H),(11-308,Bu,C-20,O,S,O,5-OH-2-Adm,H),(11-309,Bu,C-21,O,S,O,5-OH-2-Adm,H),(11-310,Bu,C-22,O,S,O,5-OH-2-Adm,H),(11-311,Bu,C-23,O,S,O,5-OH-2-Adm,H),(11-312,Bu,C-24,O,S,O,5-OH-2-Adm,H),(11-313,Bu,C-25,O,S,O,5-OH-2-Adm,H),(11-314,Bu,C-26,O,S,O,5-OH-2-Adm,H),(11-315,Bu,C-27,O,S,O,5-OH-2-Adm,H),(11-316,Bu,C-28,O,S,O,5-OH-2-Adm,H),(11-317,Bu,C-29,O,S,O,5-OH-2-Adm,H),(11-318,Bu,C-30,O,S,O,5-OH-2-Adm,H),(11-319,Bu,C-31,O,S,O,5-OH-2-Adm,H),(11-320,Bu,C-32,O,S,O,5-OH-2-Adm,H),(11-321,Bu,C-33,O,S,O,5-OH-2-Adm,H),(11-322,Bu,C-34,O,S,O,5-OH-2-Adm,H),(11-323,Bu,C-35,O,S,O,5-OH-2-Adm,H),(11-324,Bu,C-36,O,S,O,5-OH-2-Adm,H),(11-325,Bu,D-1,O,S,O,1-Adm,H),(11-326,Bu,D-2,O,S,O,1-Adm,H),(11-327,Bu,D-3,O,S,O,1-Adm,H),(11-328,Bu,D-4,O,S,O,1-Adm,H),(11-329,Bu,D-5,O,S,O,1-Adm,H),(11-330,Bu,D-6,O,S,O,1-Adm,H),(11-331,Bu,D-7,O,S,O,1-Adm,H),(11-332,Bu,D-8,O,S,O,1-Adm,H),(11-333,Bu,D-9,O,S,O,1-Adm,H),(11-334,Bu,D-10,O,S,O,1-Adm,H),(11-335,Bu,D-11,O,S,O,1-Adm,H),(11-336,Bu,D-12,O,S,O,1-Adm,H),(11-337,Bu,D-13,O,S,O,1-Adm,H),(11-338,Bu,D-14,O,S,O,1-Adm,H),(11-339,Bu,D-15,O,S,O,1-Adm,H),(11-340,Bu,D-16,O,S,O,1-Adm,H),(11-341,Bu,D-17,O,S,O,1-Adm,H),(11-342,Bu,D-18,O,S,O,1-Adm,H),(11-343,Bu,D-19,O,S,O,1-Adm,H),(11-344,Bu,D-20,O,S,O,1-Adm,H),(11-345,Bu,D-21,O,S,O,1-Adm,H),(11-346,Bu,D-22,O,S,O,1-Adm,H),(11-347,Bu,D-23,O,S,O,1-Adm,H),(11-348,Bu,D-24,O,S,O,1-Adm,H),(11-349,Bu,D-25,O,S,O,1-Adm,H),(11-350,Bu,D-26,O,S,O,1-Adm,H),(11-351,Bu,D-27,O,S,O,1-Adm,H),(11-352,Bu,D-28,O,S,O,1-Adm,H),(11-353,Bu,D-29,O,S,O,1-Adm,H),(11-354,Bu,D-30,O,S,O,1-Adm,H),(11-355,Bu,D-31,O,S,O,1-Adm,H),(11-356,Bu,D-32,O,S,O,1-Adm,H),(11-357,Bu,D-33,O,S,O,1-Adm,H),(11-358,Bu,D-34,O,S,O,1-Adm,H),(11-359,Bu,D-35,O,S,O,1-Adm,H),(11-360,Bu,D-36,O,S,O,1-Adm,H),(11-361,Bu,D-1,O,S,O,2-Adm,H),(11-362,Bu,D-2,O,S,O,2-Adm,H),(11-363,Bu,D-3,O,S,O,2-Adm,H),(11-364,Bu,D-4,O,S,O,2-Adm,H),(11-365,Bu,D-5,O,S,O,2-Adm,H),(11-366,Bu,D-6,O,S,O,2-Adm,H),(11-367,Bu,D-7,O,S,O,2-Adm,H),(11-368,Bu,D-8,O,S,O,2-Adm,H),(11-369,Bu,D-9,O,S,O,2-Adm,H),(11-370,Bu,D-10,O,S,O,2-Adm,H),(11-371,Bu,D-11,O,S,O,2-Adm,H),(11-372,Bu,D-12,O,S,O,2-Adm,H),(11-373,Bu,D-13,O,S,O,2-Adm,H),(11-374,Bu,D-14,O,S,O,2-Adm,H),(11-375,Bu,D-15,O,S,O,2-Adm,H),(11-376,Bu,D-16,O,S,O,2-Adm,H),(11-377,Bu,D-17,O,S,O,2-Adm,H),(11-378,Bu,D-18,O,S,O,2-Adm,H),(11-379,Bu,D-19,O,S,O,2-Adm,H),(11-380,Bu,D-20,O,S,O,2-Adm,H),(11-381,Bu,D-21,O,S,O,2-Adm,H),(11-382,Bu,D-22,O,S,O,2-Adm,H),(11-383,Bu,D-23,O,S,O,2-Adm,H),(11-384,Bu,D-24,O,S,O,2-Adm,H),(11-385,Bu,D-25,O,S,O,2-Adm,H),(11-386,Bu,D-26,O,S,O,2-Adm,H),(11-387,Bu,D-27,O,S,O,2-Adm,H),(11-388,Bu,D-28,O,S,O,2-Adm,H),(11-389,Bu,D-29,O,S,O,2-Adm,H),(11-390,Bu,D-30,O,S,O,2-Adm,H),(11-391,Bu,D-31,O,S,O,2-Adm,H),(11-392,Bu,D-32,O,S,O,2-Adm,H),(11-393,Bu,D-33,O,S,O,2-Adm,H),(11-394,Bu,D-34,O,S,O,2-Adm,H),(11-395,Bu,D-35,O,S,O,2-Adm,H),(11-396,Bu,D-36,O,S,O,2-Adm,H),(11-397,Bu,D-1,O,S,O,5-OH-2-Adm,H),(11-398,Bu,D-2,O,S,O,5-OH-2-Adm,H),(11-399,Bu,D-3,O,S,O,5-OH-2-Adm,H),(11-400,Bu,D-4,O,S,O,5-OH-2-Adm,H),(11-401,Bu,D-5,O,S,O,5-OH-2-Adm,H),(11-402,Bu,D-6,O,S,O,5-OH-2-Adm,H),(11-403,Bu,D-7,O,S,O,5-OH-2-Adm,H),(11-404,Bu,D-8,O,S,O,5-OH-2-Adm,H),(11-405,Bu,D-9,O,S,O,5-OH-2-Adm,H),(11-406,Bu,D-10,O,S,O,5-OH-2-Adm,H),(11-407,Bu,D-11,O,S,O,5-OH-2-Adm,H),(11-408,Bu,D-12,O,S,O,5-OH-2-Adm,H),(11-409,Bu,D-13,O,S,O,5-OH-2-Adm,H),(11-410,Bu,D-14,O,S,O,5-OH-2-Adm,H),(11-411,Bu,D-15,O,S,O,5-OH-2-Adm,H),(11-412,Bu,D-16,O,S,O,5-OH-2-Adm,H),(11-413,Bu,D-17,O,S,O,5-OH-2-Adm,H),(11-414,Bu,D-18,O,S,O,5-OH-2-Adm,H),(11-415,Bu,D-19,O,S,O,5-OH-2-Adm,H),(11-416,Bu,D-20,O,S,O,5-OH-2-Adm,H),(11-417,Bu,D-21,O,S,O,5-OH-2-Adm,H),(11-418,Bu,D-22,O,S,O,5-OH-2-Adm,H),(11-419,Bu,D-23,O,S,O,5-OH-2-Adm,H),(11-420,Bu,D-24,O,S,O,5-OH-2-Adm,H),(11-421,Bu,D-25,O,S,O,5-OH-2-Adm,H),(11-422,Bu,D-26,O,S,O,5-OH-2-Adm,H),(11-423,Bu,D-27,O,S,O,5-OH-2-Adm,H),(11-424,Bu,D-28,O,S,O,5-OH-2-Adm,H),(11-425,Bu,D-29,O,S,O,5-OH-2-Adm,H),(11-426,Bu,D-30,O,S,O,5-OH-2-Adm,H),(11-427,Bu,D-31,O,S,O,5-OH-2-Adm,H),(11-428,Bu,D-32,O,S,O,5-OH-2-Adm,H),(11-429,Bu,D-33,O,S,O,5-OH-2-Adm,H),(11-430,Bu,D-34,O,S,O,5-OH-2-Adm,H),(11-431,Bu,D-35,O,S,O,5-OH-2-Adm,H),(11-432,Bu,D-36,O,S,O,5-OH-2-Adm,H),(11-433,Bu,E-1,O,S,O,1-Adm,H),(11-434,Bu,E-2,O,S,O,1-Adm,H),(11-435,Bu,E-3,O,S,O,1-Adm,H),(11-436,Bu,E-4,O,S,O,1-Adm,H),(11-437,Bu,E-5,O,S,O,1-Adm,H),(11-438,Bu,E-6,O,S,O,1-Adm,H),(11-439,Bu,E-7,O,S,O,1-Adm,H),(11-440,Bu,E-8,O,S,O,1-Adm,H),(11-441,Bu,E-9,O,S,O,1-Adm,H),(11-442,Bu,E-10,O,S,O,1-Adm,H),(11-443,Bu,E-11,O,S,O,1-Adm,H),(11-444,Bu,E-12,O,S,O,1-Adm,H),(11-445,Bu,E-13,O,S,O,1-Adm,H),(11-446,Bu,E-14,O,S,O,1-Adm,H),(11-447,Bu,E-15,O,S,O,1-Adm,H),(11-448,Bu,E-16,O,S,O,1-Adm,H),(11-449,Bu,E-17,O,S,O,1-Adm,H),(11-450,Bu,E-18,O,S,O,1-Adm,H),(11-451,Bu,E-19,O,S,O,1-Adm,H),(11-452,Bu,E-20,O,S,O,1-Adm,H),(11-453,Bu,E-21,O,S,O,1-Adm,H),(11-454,Bu,E-22,O,S,O,1-Adm,H),(11-455,Bu,E-23,O,S,O,1-Adm,H),(11-456,Bu,E-24,O,S,O,1-Adm,H),(11-457,Bu,E-25,O,S,O,1-Adm,H),(11-458,Bu,E-26,O,S,O,1-Adm,H),(11-459,Bu,E-27,O,S,O,1-Adm,H),(11-460,Bu,E-28,O,S,O,1-Adm,H),(11-461,Bu,E-29,O,S,O,1-Adm,H),(11-462,Bu,E-30,O,S,O,1-Adm,H),(11-463,Bu,E-31,O,S,O,1-Adm,H),(11-464,Bu,E-32,O,S,O,1-Adm,H),(11-465,Bu,E-33,O,S,O,1-Adm,H),(11-466,Bu,E-34,O,S,O,1-Adm,H),(11-467,Bu,E-35,O,S,O,1-Adm,H),(11-468,Bu,E-36,O,S,O,1-Adm,H),(11-469,Bu,E-1,O,S,O,2-Adm,H),(11-470,Bu,E-2,O,S,O,2-Adm,H),(11-471,Bu,E-3,O,S,O,2-Adm,H),(11-472,Bu,E-4,O,S,O,2-Adm,H),(11-473,Bu,E-5,O,S,O,2-Adm,H),(11-474,Bu,E-6,O,S,O,2-Adm,H),(11-475,Bu,E-7,O,S,O,2-Adm,H),(11-476,Bu,E-8,O,S,O,2-Adm,H),(11-477,Bu,E-9,O,S,O,2-Adm,H),(11-478,Bu,E-10,O,S,O,2-Adm,H),(11-479,Bu,E-11,O,S,O,2-Adm,H),(11-480,Bu,E-12,O,S,O,2-Adm,H),(11-481,Bu,E-13,O,S,O,2-Adm,H),(11-482,Bu,E-14,O,S,O,2-Adm,H),(11-483,Bu,E-15,O,S,O,2-Adm,H),(11-484,Bu,E-16,O,S,O,2-Adm,H),(11-485,Bu,E-17,O,S,O,2-Adm,H),(11-486,Bu,E-18,O,S,O,2-Adm,H),(11-487,Bu,E-19,O,S,O,2-Adm,H),(11-488,Bu,E-20,O,S,O,2-Adm,H),(11-489,Bu,E-21,O,S,O,2-Adm,H),(11-490,Bu,E-22,O,S,O,2-Adm,H),(11-491,Bu,E-23,O,S,O,2-Adm,H),(11-492,Bu,E-24,O,S,O,2-Adm,H),(11-493,Bu,E-25,O,S,O,2-Adm,H),(11-494,Bu,E-26,O,S,O,2-Adm,H),(11-495,Bu,E-27,O,S,O,2-Adm,H),(11-496,Bu,E-28,O,S,O,2-Adm,H),(11-497,Bu,E-29,O,S,O,2-Adm,H),(11-498,Bu,E-30,O,S,O,2-Adm,H),(11-499,Bu,E-31,O,S,O,2-Adm,H),(11-500,Bu,E-32,O,S,O,2-Adm,H),(11-501,Bu,E-33,O,S,O,2-Adm,H),(11-502,Bu,E-34,O,S,O,2-Adm,H),(11-503,Bu,E-35,O,S,O,2-Adm,H),(11-504,Bu,E-36,O,S,O,2-Adm,H),(11-505,Bu,E-1,O,S,O,5-OH-2-Adm,H),(11-506,Bu,E-2,O,S,O,5-OH-2-Adm,H),(11-507,Bu,E-3,O,S,O,5-OH-2-Adm,H),(11-508,Bu,E-4,O,S,O,5-OH-2-Adm,H),(11-509,Bu,E-5,O,S,O,5-OH-2-Adm,H),(11-510,Bu,E-6,O,S,O,5-OH-2-Adm,H),(11-511,Bu,E-7,O,S,O,5-OH-2-Adm,H),(11-512,Bu,E-8,O,S,O,5-OH-2-Adm,H),(11-513,Bu,E-9,O,S,O,5-OH-2-Adm,H),(11-514,Bu,E-10,O,S,O,5-OH-2-Adm,H),(11-515,Bu,E-11,O,S,O,5-OH-2-Adm,H),(11-516,Bu,E-12,O,S,O,5-OH-2-Adm,H),(11-517,Bu,E-13,O,S,O,5-OH-2-Adm,H),(11-518,Bu,E-14,O,S,O,5-OH-2-Adm,H),(11-519,Bu,E-15,O,S,O,5-OH-2-Adm,H),(11-520,Bu,E-16,O,S,O,5-OH-2-Adm,H),(11-521,Bu,E-17,O,S,O,5-OH-2-Adm,H),(11-522,Bu,E-18,O,S,O,5-OH-2-Adm,H),(11-523,Bu,E-19,O,S,O,5-OH-2-Adm,H),(11-524,Bu,E-20,O,S,O,5-OH-2-Adm,H),(11-525,Bu,E-21,O,S,O,5-OH-2-Adm,H),(11-526,Bu,E-22,O,S,O,5-OH-2-Adm,H),(11-527,Bu,E-23,O,S,O,5-OH-2-Adm,H),(11-528,Bu,E-24,O,S,O,5-OH-2-Adm,H),(11-529,Bu,E-25,O,S,O,5-OH-2-Adm,H),(11-530,Bu,E-26,O,S,O,5-OH-2-Adm,H),(11-531,Bu,E-27,O,S,O,5-OH-2-Adm,H),(11-532,Bu,E-28,O,S,O,5-OH-2-Adm,H),(11-533,Bu,E-29,O,S,O,5-OH-2-Adm,H),(11-534,Bu,E-30,O,S,O,5-OH-2-Adm,H),(11-535,Bu,E-31,O,S,O,5-OH-2-Adm,H),(11-536,Bu,E-32,O,S,O,5-OH-2-Adm,H),(11-537,Bu,E-33,O,S,O,5-OH-2-Adm,H),(11-538,Bu,E-34,O,S,O,5-OH-2-Adm,H),(11-539,Bu,E-35,O,S,O,5-OH-2-Adm,H),(11-540,Bu,E-36,O,S,O,5-OH-2-Adm,H),(11-541,Bu,F-1,O,S,O,1-Adm,H),(11-542,Bu,F-2,O,S,O,1-Adm,H),(11-543,Bu,F-3,O,S,O,1-Adm,H),(11-544,Bu,F-4,O,S,O,1-Adm,H),(11-545,Bu,F-5,O,S,O,1-Adm,H),(11-546,Bu,F-6,O,S,O,1-Adm,H),(11-547,Bu,F-7,O,S,O,1-Adm,H),(11-548,Bu,F-8,O,S,O,1-Adm,H),(11-549,Bu,F-9,O,S,O,1-Adm,H),(11-550,Bu,F-10,O,S,O,1-Adm,H),(11-551,Bu,F-11,O,S,O,1-Adm,H),(11-552,Bu,F-12,O,S,O,1-Adm,H),(11-553,Bu,F-13,O,S,O,1-Adm,H),(11-554,Bu,F-14,O,S,O,1-Adm,H),(11-555,Bu,F-15,O,S,O,1-Adm,H),(11-556,Bu,F-16,O,S,O,1-Adm,H),(11-557,Bu,F-17,O,S,O,1-Adm,H),(11-558,Bu,F-18,O,S,O,1-Adm,H),(11-559,Bu,F-19,O,S,O,1-Adm,H),(11-560,Bu,F-20,O,S,O,1-Adm,H),(11-561,Bu,F-21,O,S,O,1-Adm,H),(11-562,Bu,F-22,O,S,O,1-Adm,H),(11-563,Bu,F-23,O,S,O,1-Adm,H),(11-564,Bu,F-24,O,S,O,1-Adm,H),(11-565,Bu,F-25,O,S,O,1-Adm,H),(11-566,Bu,F-26,O,S,O,1-Adm,H),(11-567,Bu,F-27,O,S,O,1-Adm,H),(11-568,Bu,F-28,O,S,O,1-Adm,H),(11-569,Bu,F-29,O,S,O,1-Adm,H),(11-570,Bu,F-30,O,S,O,1-Adm,H),(11-571,Bu,F-31,O,S,O,1-Adm,H),(11-572,Bu,F-32,O,S,O,1-Adm,H),(11-573,Bu,F-33,O,S,O,1-Adm,H),(11-574,Bu,F-34,O,S,O,1-Adm,H),(11-575,Bu,F-35,O,S,O,1-Adm,H),(11-576,Bu,F-36,O,S,O,1-Adm,H),(11-577,Bu,F-1,O,S,O,2-Adm,H),(11-578,Bu,F-2,O,S,O,2-Adm,H),(11-579,Bu,F-3,O,S,O,2-Adm,H),(11-580,Bu,F-4,O,S,O,2-Adm,H),(11-581,Bu,F-5,O,S,O,2-Adm,H),(11-582,Bu,F-6,O,S,O,2-Adm,H),(11-583,Bu,F-7,O,S,O,2-Adm,H),(11-584,Bu,F-8,O,S,O,2-Adm,H),(11-585,Bu,F-9,O,S,O,2-Adm,H),(11-586,Bu,F-10,O,S,O,2-Adm,H),(11-587,Bu,F-11,O,S,O,2-Adm,H),(11-588,Bu,F-12,O,S,O,2-Adm,H),(11-589,Bu,F-13,O,S,O,2-Adm,H),(11-590,Bu,F-14,O,S,O,2-Adm,H),(11-591,Bu,F-15,O,S,O,2-Adm,H),(11-592,Bu,F-16,O,S,O,2-Adm,H),(11-593,Bu,F-17,O,S,O,2-Adm,H),(11-594,Bu,F-18,O,S,O,2-Adm,H),(11-595,Bu,F-19,O,S,O,2-Adm,H),(11-596,Bu,F-20,O,S,O,2-Adm,H),(11-597,Bu,F-21,O,S,O,2-Adm,H),(11-598,Bu,F-22,O,S,O,2-Adm,H),(11-599,Bu,F-23,O,S,O,2-Adm,H),(11-600,Bu,F-24,O,S,O,2-Adm,H),(11-601,Bu,F-25,O,S,O,2-Adm,H),(11-602,Bu,F-26,O,S,O,2-Adm,H),(11-603,Bu,F-27,O,S,O,2-Adm,H),(11-604,Bu,F-28,O,S,O,2-Adm,H),(11-605,Bu,F-29,O,S,O,2-Adm,H),(11-606,Bu,F-30,O,S,O,2-Adm,H),(11-607,Bu,F-31,O,S,O,2-Adm,H),(11-608,Bu,F-32,O,S,O,2-Adm,H),(11-609,Bu,F-33,O,S,O,2-Adm,H),(11-610,Bu,F-34,O,S,O,2-Adm,H),(11-611,Bu,F-35,O,S,O,2-Adm,H),(11-612,Bu,F-36,O,S,O,2-Adm,H),(11-613,Bu,F-1,O,S,O,5-OH-2-Adm,H),(11-614,Bu,F-2,O,S,O,5-OH-2-Adm,H),(11-615,Bu,F-3,O,S,O,5-OH-2-Adm,H),(11-616,Bu,F-4,O,S,O,5-OH-2-Adm,H),(11-617,Bu,F-5,O,S,O,5-OH-2-Adm,H),(11-618,Bu,F-6,O,S,O,5-OH-2-Adm,H),(11-619,Bu,F-7,O,S,O,5-OH-2-Adm,H),(11-620,Bu,F-8,O,S,O,5-OH-2-Adm,H),(11-621,Bu,F-9,O,S,O,5-OH-2-Adm,H),(11-622,Bu,F-10,O,S,O,5-OH-2-Adm,H),(11-623,Bu,F-11,O,S,O,5-OH-2-Adm,H),(11-624,Bu,F-12,O,S,O,5-OH-2-Adm,H),(11-625,Bu,F-13,O,S,O,5-OH-2-Adm,H),(11-626,Bu,F-14,O,S,O,5-OH-2-Adm,H),(11-627,Bu,F-15,O,S,O,5-OH-2-Adm,H),(11-628,Bu,F-16,O,S,O,5-OH-2-Adm,H),(11-629,Bu,F-17,O,S,O,5-OH-2-Adm,H),(11-630,Bu,F-18,O,S,O,5-OH-2-Adm,H),(11-631,Bu,F-19,O,S,O,5-OH-2-Adm,H),(11-632,Bu,F-20,O,S,O,5-OH-2-Adm,H),(11-633,Bu,F-21,O,S,O,5-OH-2-Adm,H),(11-634,Bu,F-22,O,S,O,5-OH-2-Adm,H),(11-635,Bu,F-23,O,S,O,5-OH-2-Adm,H),(11-636,Bu,F-24,O,S,O,5-OH-2-Adm,H),(11-637,Bu,F-25,O,S,O,5-OH-2-Adm,H),(11-638,Bu,F-26,O,S,O,5-OH-2-Adm,H),(11-639,Bu,F-27,O,S,O,5-OH-2-Adm,H),(11-640,Bu,F-28,O,S,O,5-OH-2-Adm,H),(11-641,Bu,F-29,O,S,O,5-OH-2-Adm,H),(11-642,Bu,F-30,O,S,O,5-OH-2-Adm,H),(11-643,Bu,F-31,O,S,O,5-OH-2-Adm,H),(11-644,Bu,F-32,O,S,O,5-OH-2-Adm,H),(11-645,Bu,F-33,O,S,O,5-OH-2-Adm,H),(11-646,Bu,F-34,O,S,O,5-OH-2-Adm,H),(11-647,Bu,F-35,O,S,O,5-OH-2-Adm,H),(11-648,Bu,F-36,O,S,O,5-OH-2-Adm,H),(11-649,Bu,G-1,O,S,O,1-Adm,H),(11-650,Bu,G-2,O,S,O,1-Adm,H),(11-651,Bu,G-3,O,S,O,1-Adm,H),(11-652,Bu,G-4,O,S,O,1-Adm,H),(11-653,Bu,G-5,O,S,O,1-Adm,H),(11-654,Bu,G-6,O,S,O,1-Adm,H),(11-655,Bu,G-7,O,S,O,1-Adm,H),(11-656,Bu,G-8,O,S,O,1-Adm,H),(11-657,Bu,G-9,O,S,O,1-Adm,H),(11-658,Bu,G-1,O,S,O,2-Adm,H),(11-659,Bu,G-2,O,S,O,2-Adm,H),(11-660,Bu,G-3,O,S,O,2-Adm,H),(11-661,Bu,G-4,O,S,O,2-Adm,H),(11-662,Bu,G-5,O,S,O,2-Adm,H),(11-663,Bu,G-6,O,S,O,2-Adm,H),(11-664,Bu,G-7,O,S,O,2-Adm,H),(11-665,Bu,G-8,O,S,O,2-Adm,H),(11-666,Bu,G-9,O,S,O,2-Adm,H),(11-667,Bu,G-1,O,S,O,5-OH-2-Adm,H),(11-668,Bu,G-2,O,S,O,5-OH-2-Adm,H),(11-669,Bu,G-3,O,S,O,5-OH-2-Adm,H),(11-670,Bu,G-4,O,S,O,5-OH-2-Adm,H),(11-671,Bu,G-5,O,S,O,5-OH-2-Adm,H),(11-672,Bu,G-6,O,S,O,5-OH-2-Adm,H),(11-673,Bu,G-7,O,S,O,5-OH-2-Adm,H),(11-674,Bu,G-8,O,S,O,5-OH-2-Adm,H),(11-675,Bu,G-9,O,S,O,5-OH-2-Adm,H),(11-676,Bu,H-1,O,S,O,1-Adm,H),(11-677,Bu,H-2,O,S,O,1-Adm,H),(11-678,Bu,H-3,O,S,O,1-Adm,H),(11-679,Bu,H-4,O,S,O,1-Adm,H),(11-680,Bu,H-5,O,S,O,1-Adm,H),(11-681,Bu,H-6,O,S,O,1-Adm,H),(11-682,Bu,H-7,O,S,O,1-Adm,H),(11-683,Bu,H-8,O,S,O,1-Adm,H),(11-684,Bu,H-9,O,S,O,1-Adm,H),(11-685,Bu,H-1,O,S,O,2-Adm,H),(11-686,Bu,H-2,O,S,O,2-Adm,H),(11-687,Bu,H-3,O,S,O,2-Adm,H),(11-688,Bu,H-4,O,S,O,2-Adm,H),(11-689,Bu,H-5,O,S,O,2-Adm,H),(11-690,Bu,H-6,O,S,O,2-Adm,H),(11-691,Bu,H-7,O,S,O,2-Adm,H),(11-692,Bu,H-8,O,S,O,2-Adm,H),(11-693,Bu,H-9,O,S,O,2-Adm,H),(11-694,Bu,H-1,O,S,O,5-OH-2-Adm,H),(11-695,Bu,H-2,O,S,O,5-OH-2-Adm,H),(11-696,Bu,H-3,O,S,O,5-OH-2-Adm,H),(11-697,Bu,H-4,O,S,O,5-OH-2-Adm,H),(11-698,Bu,H-5,O,S,O,5-OH-2-Adm,H),(11-699,Bu,H-6,O,S,O,5-OH-2-Adm,H),(11-700,Bu,H-7,O,S,O,5-OH-2-Adm,H),(11-701,Bu,H-8,O,S,O,5-OH-2-Adm,H),(11-702,Bu,H-9,O,S,O,5-OH-2-Adm,H),(11-703,Bu,I-1,O,S,O,1-Adm,H),(11-704,Bu,I-2,O,S,O,1-Adm,H),(11-705,Bu,I-3,O,S,O,1-Adm,H),(11-706,Bu,I-4,O,S,O,1-Adm,H),(11-707,Bu,I-5,O,S,O,1-Adm,H),(11-708,Bu,I-6,O,S,O,1-Adm,H),(11-709,Bu,I-7,O,S,O,1-Adm,H),(11-710,Bu,I-8,O,S,O,1-Adm,H),(11-711,Bu,I-9,O,S,O,1-Adm,H),(11-712,Bu,I-1,O,S,O,2-Adm,H),(11-713,Bu,I-2,O,S,O,2-Adm,H),(11-714,Bu,I-3,O,S,O,2-Adm,H),(11-715,Bu,I-4,O,S,O,2-Adm,H),(11-716,Bu,I-5,O,S,O,2-Adm,H),(11-717,Bu,I-6,O,S,O,2-Adm,H),(11-718,Bu,I-7,O,S,O,2-Adm,H),(11-719,Bu,I-8,O,S,O,2-Adm,H),(11-720,Bu,I-9,O,S,O,2-Adm,H),(11-721,Bu,I-1,O,S,O,5-OH-2-Adm,H),(11-722,Bu,I-2,O,S,O,5-OH-2-Adm,H),(11-723,Bu,I-3,O,S,O,5-OH-2-Adm,H),(11-724,Bu,I-4,O,S,O,5-OH-2-Adm,H),(11-725,Bu,I-5,O,S,O,5-OH-2-Adm,H),(11-726,Bu,I-6,O,S,O,5-OH-2-Adm,H),(11-727,Bu,I-7,O,S,O,5-OH-2-Adm,H),(11-728,Bu,I-8,O,S,O,5-OH-2-Adm,H),(11-729,Bu,I-9,O,S,O,5-OH-2-Adm,H),(11-730,Bu,J-1,O,S,O,1-Adm,H),(11-731,Bu,J-2,O,S,O,1-Adm,H),(11-732,Bu,J-3,O,S,O,1-Adm,H),(11-733,Bu,J-4,O,S,O,1-Adm,H),(11-734,Bu,J-5,O,S,O,1-Adm,H),(11-735,Bu,J-6,O,S,O,1-Adm,H),(11-736,Bu,J-7,O,S,O,1-Adm,H),(11-737,Bu,J-8,O,S,O,1-Adm,H),(11-738,Bu,J-9,O,S,O,1-Adm,H),(11-739,Bu,J-1,O,S,O,2-Adm,H),(11-740,Bu,J-2,O,S,O,2-Adm,H),(11-741,Bu,J-3,O,S,O,2-Adm,H),(11-742,Bu,J-4,O,S,O,2-Adm,H),(11-743,Bu,J-5,O,S,O,2-Adm,H),(11-744,Bu,J-6,O,S,O,2-Adm,H),(11-745,Bu,J-7,O,S,O,2-Adm,H),(11-746,Bu,J-8,O,S,O,2-Adm,H),(11-747,Bu,J-9,O,S,O,2-Adm,H),(11-748,Bu,J-1,O,S,O,5-OH-2-Adm,H),(11-749,Bu,J-2,O,S,O,5-OH-2-Adm,H),(11-750,Bu,J-3,O,S,O,5-OH-2-Adm,H),(11-751,Bu,J-4,O,S,O,5-OH-2-Adm,H),(11-752,Bu,J-5,O,S,O,5-OH-2-Adm,H),(11-753,Bu,J-6,O,S,O,5-OH-2-Adm,H),(11-754,Bu,J-7,O,S,O,5-OH-2-Adm,H),(11-755,Bu,J-8,O,S,O,5-OH-2-Adm,H),(11-756,Bu,J-9,O,S,O,5-OH-2-Adm,H),(11-757,Bu,K-1,O,S,O,1-Adm,H),(11-758,Bu,K-2,O,S,O,1-Adm,H),(11-759,Bu,K-3,O,S,O,1-Adm,H),(11-760,Bu,K-4,O,S,O,1-Adm,H),(11-761,Bu,K-5,O,S,O,1-Adm,H),(11-762,Bu,K-6,O,S,O,1-Adm,H),(11-763,Bu,K-7,O,S,O,1-Adm,H),(11-764,Bu,K-8,O,S,O,1-Adm,H),(11-765,Bu,K-9,O,S,O,1-Adm,H),(11-766,Bu,K-1,O,S,O,2-Adm,H),(11-767,Bu,K-2,O,S,O,2-Adm,H),(11-768,Bu,K-3,O,S,O,2-Adm,H),(11-769,Bu,K-4,O,S,O,2-Adm,H),(11-770,Bu,K-5,O,S,O,2-Adm,H),(11-771,Bu,K-6,O,S,O,2-Adm,H),(11-772,Bu,K-7,O,S,O,2-Adm,H),(11-773,Bu,K-8,O,S,O,2-Adm,H),(11-774,Bu,K-9,O,S,O,2-Adm,H),(11-775,Bu,K-1,O,S,O,5-OH-2-Adm,H),(11-776,Bu,K-2,O,S,O,5-OH-2-Adm,H),(11-777,Bu,K-3,O,S,O,5-OH-2-Adm,H),(11-778,Bu,K-4,O,S,O,5-OH-2-Adm,H),(11-779,Bu,K-5,O,S,O,5-OH-2-Adm,H),(11-780,Bu,K-6,O,S,O,5-OH-2-Adm,H),(11-781,Bu,K-7,O,S,O,5-OH-2-Adm,H),(11-782,Bu,K-8,O,S,O,5-OH-2-Adm,H),(11-783,Bu,K-9,O,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(12-1,i-Pro,A-1,O,S,O,1-Adm,H),(12-2,i-Pro,A-2,O,S,O,1-Adm,H),(12-3,i-Pro,A-3,O,S,O,1-Adm,H),(12-4,i-Pro,A-4,O,S,O,1-Adm,H),(12-5,i-Pro,A-5,O,S,O,1-Adm,H),(12-6,i-Pro,A-6,O,S,O,1-Adm,H),(12-7,i-Pro,A-7,O,S,O,1-Adm,H),(12-8,i-Pro,A-8,O,S,O,1-Adm,H),(12-9,i-Pro,A-9,O,S,O,1-Adm,H),(12-10,i-Pro,A-10,O,S,O,1-Adm,H),(12-11,i-Pro,A-11,O,S,O,1-Adm,H),(12-12,i-Pro,A-12,O,S,O,1-Adm,H),(12-13,i-Pro,A-13,O,S,O,1-Adm,H),(12-14,i-Pro,A-14,O,S,O,1-Adm,H),(12-15,i-Pro,A-15,O,S,O,1-Adm,H),(12-16,i-Pro,A-16,O,S,O,1-Adm,H),(12-17,i-Pro,A-17,O,S,O,1-Adm,H),(12-18,i-Pro,A-18,O,S,O,1-Adm,H),(12-19,i-Pro,A-19,O,S,O,1-Adm,H),(12-20,i-Pro,A-20,O,S,O,1-Adm,H),(12-21,i-Pro,A-21,O,S,O,1-Adm,H),(12-22,i-Pro,A-22,O,S,O,1-Adm,H),(12-23,i-Pro,A-23,O,S,O,1-Adm,H),(12-24,i-Pro,A-24,O,S,O,1-Adm,H),(12-25,i-Pro,A-25,O,S,O,1-Adm,H),(12-26,i-Pro,A-26,O,S,O,1-Adm,H),(12-27,i-Pro,A-27,O,S,O,1-Adm,H),(12-28,i-Pro,A-28,O,S,O,1-Adm,H),(12-29,i-Pro,A-29,O,S,O,1-Adm,H),(12-30,i-Pro,A-30,O,S,O,1-Adm,H),(12-31,i-Pro,A-31,O,S,O,1-Adm,H),(12-32,i-Pro,A-32,O,S,O,1-Adm,H),(12-33,i-Pro,A-33,O,S,O,1-Adm,H),(12-34,i-Pro,A-34,O,S,O,1-Adm,H),(12-35,i-Pro,A-35,O,S,O,1-Adm,H),(12-36,i-Pro,A-36,O,S,O,1-Adm,H),(12-37,i-Pro,A-1,O,S,O,2-Adm,H),(12-38,i-Pro,A-2,O,S,O,2-Adm,H),(12-39,i-Pro,A-3,O,S,O,2-Adm,H),(12-40,i-Pro,A-4,O,S,O,2-Adm,H),(12-41,i-Pro,A-5,O,S,O,2-Adm,H),(12-42,i-Pro,A-6,O,S,O,2-Adm,H),(12-43,i-Pro,A-7,O,S,O,2-Adm,H),(12-44,i-Pro,A-9,O,S,O,2-Adm,H),(12-45,i-Pro,A-11,O,S,O,2-Adm,H),(12-46,i-Pro,A-12,O,S,O,2-Adm,H),(12-47,i-Pro,A-13,O,S,O,2-Adm,H),(12-48,i-Pro,A-14,O,S,O,2-Adm,H),(12-49,i-Pro,A-15,O,S,O,2-Adm,H),(12-50,i-Pro,A-16,O,S,O,2-Adm,H),(12-51,i-Pro,A-17,O,S,O,2-Adm,H),(12-52,i-Pro,A-18,O,S,O,2-Adm,H),(12-53,i-Pro,A-20,O,S,O,2-Adm,H),(12-54,i-Pro,A-21,O,S,O,2-Adm,H),(12-55,i-Pro,A-22,O,S,O,2-Adm,H),(12-56,i-Pro,A-23,O,S,O,2-Adm,H),(12-57,i-Pro,A-24,O,S,O,2-Adm,H),(12-58,i-Pro,A-26,O,S,O,2-Adm,H),(12-59,i-Pro,A-27,O,S,O,2-Adm,H),(12-60,i-Pro,A-28,O,S,O,2-Adm,H),(12-61,i-Pro,A-29,O,S,O,2-Adm,H),(12-62,i-Pro,A-30,O,S,O,2-Adm,H),(12-63,i-Pro,A-31,O,S,O,2-Adm,H),(12-64,i-Pro,A-32,O,S,O,2-Adm,H),(12-65,i-Pro,A-33,O,S,O,2-Adm,H),(12-66,i-Pro,A-34,O,S,O,2-Adm,H),(12-67,i-Pro,A-35,O,S,O,2-Adm,H),(12-68,i-Pro,A-36,O,S,O,2-Adm,H),(12-69,i-Pro,A-1,O,S,O,5-OH-2-Adm,H),(12-70,i-Pro,A-2,O,S,O,5-OH-2-Adm,H),(12-71,i-Pro,A-3,O,S,O,5-OH-2-Adm,H),(12-72,i-Pro,A-4,O,S,O,5-OH-2-Adm,H),(12-73,i-Pro,A-5,O,S,O,5-OH-2-Adm,H),(12-74,i-Pro,A-6,O,S,O,5-OH-2-Adm,H),(12-75,i-Pro,A-7,O,S,O,5-OH-2-Adm,H),(12-76,i-Pro,A-8,O,S,O,5-OH-2-Adm,H),(12-77,i-Pro,A-9,O,S,O,5-OH-2-Adm,H),(12-78,i-Pro,A-10,O,S,O,5-OH-2-Adm,H),(12-79,i-Pro,A-11,O,S,O,5-OH-2-Adm,H),(12-80,i-Pro,A-12,O,S,O,5-OH-2-Adm,H),(12-81,i-Pro,A-13,O,S,O,5-OH-2-Adm,H),(12-82,i-Pro,A-14,O,S,O,5-OH-2-Adm,H),(12-83,i-Pro,A-15,O,S,O,5-OH-2-Adm,H),(12-84,i-Pro,A-16,O,S,O,5-OH-2-Adm,H),(12-85,i-Pro,A-17,O,S,O,5-OH-2-Adm,H),(12-86,i-Pro,A-18,O,S,O,5-OH-2-Adm,H),(12-87,i-Pro,A-19,O,S,O,5-OH-2-Adm,H),(12-88,i-Pro,A-20,O,S,O,5-OH-2-Adm,H),(12-89,i-Pro,A-21,O,S,O,5-OH-2-Adm,H),(12-90,i-Pro,A-22,O,S,O,5-OH-2-Adm,H),(12-91,i-Pro,A-23,O,S,O,5-OH-2-Adm,H),(12-92,i-Pro,A-24,O,S,O,5-OH-2-Adm,H),(12-93,i-Pro,A-25,O,S,O,5-OH-2-Adm,H),(12-94,i-Pro,A-26,O,S,O,5-OH-2-Adm,H),(12-95,i-Pro,A-27,O,S,O,5-OH-2-Adm,H),(12-96,i-Pro,A-28,O,S,O,5-OH-2-Adm,H),(12-97,i-Pro,A-29,O,S,O,5-OH-2-Adm,H),(12-98,i-Pro,A-30,O,S,O,5-OH-2-Adm,H),(12-99,i-Pro,A-31,O,S,O,5-OH-2-Adm,H),(12-100,i-Pro,A-32,O,S,O,5-OH-2-Adm,H),(12-101,i-Pro,A-33,O,S,O,5-OH-2-Adm,H),(12-102,i-Pro,A-34,O,S,O,5-OH-2-Adm,H),(12-103,i-Pro,A-35,O,S,O,5-OH-2-Adm,H),(12-104,i-Pro,A-36,O,S,O,5-OH-2-Adm,H),(12-105,i-Pro,B-1,O,S,O,1-Adm,H),(12-106,i-Pro,B-2,O,S,O,1-Adm,H),(12-107,i-Pro,B-3,O,S,O,1-Adm,H),(12-108,i-Pro,B-4,O,S,O,1-Adm,H),(12-109,i-Pro,B-5,O,S,O,1-Adm,H),(12-111,i-Pro,B-6,O,S,O,1-Adm,H),(12-111,i-Pro,B-7,O,S,O,1-Adm,H),(12-112,i-Pro,B-8,O,S,O,1-Adm,H),(12-113,i-Pro,B-9,O,S,O,1-Adm,H),(12-114,i-Pro,B-11,O,S,O,1-Adm,H),(12-115,i-Pro,B-11,O,S,O,1-Adm,H),(12-116,i-Pro,B-12,O,S,O,1-Adm,H),(12-117,i-Pro,B-13,O,S,O,1-Adm,H),(12-118,i-Pro,B-14,O,S,O,1-Adm,H),(12-119,i-Pro,B-15,O,S,O,1-Adm,H),(12-120,i-Pro,B-16,O,S,O,1-Adm,H),(12-121,i-Pro,B-17,O,S,O,1-Adm,H),(12-122,i-Pro,B-18,O,S,O,1-Adm,H),(12-123,i-Pro,B-19,O,S,O,1-Adm,H),(12-124,i-Pro,B-20,O,S,O,1-Adm,H),(12-125,i-Pro,B-21,O,S,O,1-Adm,H),(12-126,i-Pro,B-22,O,S,O,1-Adm,H),(12-127,i-Pro,B-23,O,S,O,1-Adm,H),(12-128,i-Pro,B-24,O,S,O,1-Adm,H),(12-129,i-Pro,B-25,O,S,O,1-Adm,H),(12-130,i-Pro,B-26,O,S,O,1-Adm,H),(12-131,i-Pro,B-27,O,S,O,1-Adm,H),(12-132,i-Pro,B-28,O,S,O,1-Adm,H),(12-133,i-Pro,B-29,O,S,O,1-Adm,H),(12-134,i-Pro,B-30,O,S,O,1-Adm,H),(12-135,i-Pro,B-31,O,S,O,1-Adm,H),(12-136,i-Pro,B-32,O,S,O,1-Adm,H),(12-137,i-Pro,B-33,O,S,O,1-Adm,H),(12-138,i-Pro,B-34,O,S,O,1-Adm,H),(12-139,i-Pro,B-35,O,S,O,1-Adm,H),(12-140,i-Pro,B-36,O,S,O,1-Adm,H),(12-141,i-Pro,B-1,O,S,O,2-Adm,H),(12-142,i-Pro,B-2,O,S,O,2-Adm,H),(12-143,i-Pro,B-3,O,S,O,2-Adm,H),(12-144,i-Pro,B-4,O,S,O,2-Adm,H),(12-145,i-Pro,B-5,O,S,O,2-Adm,H),(12-146,i-Pro,B-6,O,S,O,2-Adm,H),(12-147,i-Pro,B-7,O,S,O,2-Adm,H),(12-148,i-Pro,B-8,O,S,O,2-Adm,H),(12-149,i-Pro,B-9,O,S,O,2-Adm,H),(12-150,i-Pro,B-11,O,S,O,2-Adm,H),(12-151,i-Pro,B-11,O,S,O,2-Adm,H),(12-152,i-Pro,B-12,O,S,O,2-Adm,H),(12-153,i-Pro,B-13,O,S,O,2-Adm,H),(12-154,i-Pro,B-14,O,S,O,2-Adm,H),(12-155,i-Pro,B-15,O,S,O,2-Adm,H),(12-156,i-Pro,B-16,O,S,O,2-Adm,H),(12-157,i-Pro,B-17,O,S,O,2-Adm,H),(12-158,i-Pro,B-18,O,S,O,2-Adm,H),(12-159,i-Pro,B-19,O,S,O,2-Adm,H),(12-160,i-Pro,B-20,O,S,O,2-Adm,H),(12-161,i-Pro,B-21,O,S,O,2-Adm,H),(12-162,i-Pro,B-22,O,S,O,2-Adm,H),(12-163,i-Pro,B-23,O,S,O,2-Adm,H),(12-164,i-Pro,B-24,O,S,O,2-Adm,H),(12-165,i-Pro,B-25,O,S,O,2-Adm,H),(12-166,i-Pro,B-26,O,S,O,2-Adm,H),(12-167,i-Pro,B-27,O,S,O,2-Adm,H),(12-168,i-Pro,B-28,O,S,O,2-Adm,H),(12-169,i-Pro,B-29,O,S,O,2-Adm,H),(12-170,i-Pro,B-30,O,S,O,2-Adm,H),(12-171,i-Pro,B-31,O,S,O,2-Adm,H),(12-172,i-Pro,B-32,O,S,O,2-Adm,H),(12-173,i-Pro,B-33,O,S,O,2-Adm,H),(12-174,i-Pro,B-34,O,S,O,2-Adm,H),(12-175,i-Pro,B-35,O,S,O,2-Adm,H),(12-176,i-Pro,B-36,O,S,O,2-Adm,H),(12-177,i-Pro,B-1,O,S,O,5-OH-2-Adm,H),(12-178,i-Pro,B-2,O,S,O,5-OH-2-Adm,H),(12-179,i-Pro,B-3,O,S,O,5-OH-2-Adm,H),(12-180,i-Pro,B-4,O,S,O,5-OH-2-Adm,H),(12-181,i-Pro,B-5,O,S,O,5-OH-2-Adm,H),(12-182,i-Pro,B-6,O,S,O,5-OH-2-Adm,H),(12-183,i-Pro,B-7,O,S,O,5-OH-2-Adm,H),(12-184,i-Pro,B-8,O,S,O,5-OH-2-Adm,H),(12-185,i-Pro,B-9,O,S,O,5-OH-2-Adm,H),(12-186,i-Pro,B-10,O,S,O,5-OH-2-Adm,H),(12-187,i-Pro,B-11,O,S,O,5-OH-2-Adm,H),(12-188,i-Pro,B-12,O,S,O,5-OH-2-Adm,H),(12-189,i-Pro,B-13,O,S,O,5-OH-2-Adm,H),(12-190,i-Pro,B-14,O,S,O,5-OH-2-Adm,H),(12-191,i-Pro,B-15,O,S,O,5-OH-2-Adm,H),(12-192,i-Pro,B-16,O,S,O,5-OH-2-Adm,H),(12-193,i-Pro,B-17,O,S,O,5-OH-2-Adm,H),(12-194,i-Pro,B-18,O,S,O,5-OH-2-Adm,H),(12-195,i-Pro,B-19,O,S,O,5-OH-2-Adm,H),(12-196,i-Pro,B-20,O,S,O,5-OH-2-Adm,H),(12-197,i-Pro,B-21,O,S,O,5-OH-2-Adm,H),(12-198,i-Pro,B-22,O,S,O,5-OH-2-Adm,H),(12-199,i-Pro,B-23,O,S,O,5-OH-2-Adm,H),(12-200,i-Pro,B-24,O,S,O,5-OH-2-Adm,H),(12-201,i-Pro,B-25,O,S,O,5-OH-2-Adm,H),(12-202,i-Pro,B-26,O,S,O,5-OH-2-Adm,H),(12-203,i-Pro,B-27,O,S,O,5-OH-2-Adm,H),(12-204,i-Pro,B-28,O,S,O,5-OH-2-Adm,H),(12-205,i-Pro,B-29,O,S,O,5-OH-2-Adm,H),(12-206,i-Pro,B-30,O,S,O,5-OH-2-Adm,H),(12-207,i-Pro,B-31,O,S,O,5-OH-2-Adm,H),(12-208,i-Pro,B-32,O,S,O,5-OH-2-Adm,H),(12-209,i-Pro,B-33,O,S,O,5-OH-2-Adm,H),(12-210,i-Pro,B-34,O,S,O,5-OH-2-Adm,H),(12-211,i-Pro,B-35,O,S,O,5-OH-2-Adm,H),(12-212,i-Pro,B-36,O,S,O,5-OH-2-Adm,H),(12-213,i-Pro,C-1,O,S,O,1-Adm,H),(12-214,i-Pro,C-2,O,S,O,1-Adm,H),(12-215,i-Pro,C-3,O,S,O,1-Adm,H),(12-216,i-Pro,C-4,O,S,O,1-Adm,H),(12-217,i-Pro,C-5,O,S,O,1-Adm,H),(12-218,i-Pro,C-6,O,S,O,1-Adm,H),(12-219,i-Pro,C-7,O,S,O,1-Adm,H),(12-220,i-Pro,C-8,O,S,O,1-Adm,H),(12-221,i-Pro,C-9,O,S,O,1-Adm,H),(12-222,i-Pro,C-10,O,S,O,1-Adm,H),(12-223,i-Pro,C-11,O,S,O,1-Adm,H),(12-224,i-Pro,C-12,O,S,O,1-Adm,H),(12-225,i-Pro,C-13,O,S,O,1-Adm,H),(12-226,i-Pro,C-14,O,S,O,1-Adm,H),(12-227,i-Pro,C-15,O,S,O,1-Adm,H),(12-228,i-Pro,C-16,O,S,O,1-Adm,H),(12-229,i-Pro,C-17,O,S,O,1-Adm,H),(12-230,i-Pro,C-18,O,S,O,1-Adm,H),(12-231,i-Pro,C-19,O,S,O,1-Adm,H),(12-232,i-Pro,C-20,O,S,O,1-Adm,H),(12-233,i-Pro,C-21,O,S,O,1-Adm,H),(12-234,i-Pro,C-22,O,S,O,1-Adm,H),(12-235,i-Pro,C-23,O,S,O,1-Adm,H),(12-236,i-Pro,C-24,O,S,O,1-Adm,H),(12-237,i-Pro,C-25,O,S,O,1-Adm,H),(12-238,i-Pro,C-26,O,S,O,1-Adm,H),(12-239,i-Pro,C-27,O,S,O,1-Adm,H),(12-240,i-Pro,C-28,O,S,O,1-Adm,H),(12-241,i-Pro,C-29,O,S,O,1-Adm,H),(12-242,i-Pro,C-30,O,S,O,1-Adm,H),(12-243,i-Pro,C-31,O,S,O,1-Adm,H),(12-244,i-Pro,C-32,O,S,O,1-Adm,H),(12-245,i-Pro,C-33,O,S,O,1-Adm,H),(12-246,i-Pro,C-34,O,S,O,1-Adm,H),(12-247,i-Pro,C-35,O,S,O,1-Adm,H),(12-248,i-Pro,C-36,O,S,O,1-Adm,H),(12-249,i-Pro,C-1,O,S,O,2-Adm,H),(12-250,i-Pro,C-2,O,S,O,2-Adm,H),(12-251,i-Pro,C-3,O,S,O,2-Adm,H),(12-252,i-Pro,C-4,O,S,O,2-Adm,H),(12-253,i-Pro,C-5,O,S,O,2-Adm,H),(12-254,i-Pro,C-6,O,S,O,2-Adm,H),(12-255,i-Pro,C-7,O,S,O,2-Adm,H),(12-256,i-Pro,C-8,O,S,O,2-Adm,H),(12-257,i-Pro,C-9,O,S,O,2-Adm,H),(12-258,i-Pro,C-10,O,S,O,2-Adm,H),(12-259,i-Pro,C-11,O,S,O,2-Adm,H),(12-260,i-Pro,C-12,O,S,O,2-Adm,H),(12-261,i-Pro,C-13,O,S,O,2-Adm,H),(12-262,i-Pro,C-14,O,S,O,2-Adm,H),(12-263,i-Pro,C-15,O,S,O,2-Adm,H),(12-264,i-Pro,C-16,O,S,O,2-Adm,H),(12-265,i-Pro,C-17,O,S,O,2-Adm,H),(12-266,i-Pro,C-18,O,S,O,2-Adm,H),(12-267,i-Pro,C-19,O,S,O,2-Adm,H),(12-268,i-Pro,C-20,O,S,O,2-Adm,H),(12-269,i-Pro,C-21,O,S,O,2-Adm,H),(12-270,i-Pro,C-22,O,S,O,2-Adm,H),(12-271,i-Pro,C-23,O,S,O,2-Adm,H),(12-272,i-Pro,C-24,O,S,O,2-Adm,H),(12-273,i-Pro,C-25,O,S,O,2-Adm,H),(12-274,i-Pro,C-26,O,S,O,2-Adm,H),(12-275,i-Pro,C-27,O,S,O,2-Adm,H),(12-276,i-Pro,C-28,O,S,O,2-Adm,H),(12-277,i-Pro,C-29,O,S,O,2-Adm,H),(12-278,i-Pro,C-30,O,S,O,2-Adm,H),(12-279,i-Pro,C-31,O,S,O,2-Adm,H),(12-280,i-Pro,C-32,O,S,O,2-Adm,H),(12-281,i-Pro,C-33,O,S,O,2-Adm,H),(12-282,i-Pro,C-34,O,S,O,2-Adm,H),(12-283,i-Pro,C-35,O,S,O,2-Adm,H),(12-284,i-Pro,C-36,O,S,O,2-Adm,H),(12-285,i-Pro,C-1,O,S,O,5-OH-2-Adm,H),(12-286,i-Pro,C-2,O,S,O,5-OH-2-Adm,H),(12-287,i-Pro,C-3,O,S,O,5-OH-2-Adm,H),(12-288,i-Pro,C-4,O,S,O,5-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(12-711,i-Pro,I-4,O,S,O,2-Adm,H),(12-712,i-Pro,I-5,O,S,O,2-Adm,H),(12-713,i-Pro,I-6,O,S,O,2-Adm,H),(12-714,i-Pro,I-7,O,S,O,2-Adm,H),(12-715,i-Pro,I-8,O,S,O,2-Adm,H),(12-716,i-Pro,I-9,O,S,O,2-Adm,H),(12-717,i-Pro,I-1,O,S,O,5-OH-2-Adm,H),(12-718,i-Pro,I-2,O,S,O,5-OH-2-Adm,H),(12-719,i-Pro,I-3,O,S,O,5-OH-2-Adm,H),(12-720,i-Pro,I-4,O,S,O,5-OH-2-Adm,H),(12-721,i-Pro,I-5,O,S,O,5-OH-2-Adm,H),(12-722,i-Pro,I-6,O,S,O,5-OH-2-Adm,H),(12-723,i-Pro,I-7,O,S,O,5-OH-2-Adm,H),(12-724,i-Pro,I-8,O,S,O,5-OH-2-Adm,H),(12-725,i-Pro,I-9,O,S,O,5-OH-2-Adm,H),(12-726,i-Pro,J-1,O,S,O,1-Adm,H),(12-727,i-Pro,J-2,O,S,O,1-Adm,H),(12-728,i-Pro,J-3,O,S,O,1-Adm,H),(12-729,i-Pro,J-4,O,S,O,1-Adm,H),(12-730,i-Pro,J-5,O,S,O,1-Adm,H),(12-731,i-Pro,J-6,O,S,O,1-Adm,H),(12-732,i-Pro,J-7,O,S,O,1-Adm,H),(12-733,i-Pro,J-8,O,S,O,1-Adm,H),(12-734,i-Pro,J-9,O,S,O,1-Adm,H),(12-735,i-Pro,J-1,O,S,O,2-Adm,H),(12-736,i-Pro,J-2,O,S,O,2-Adm,H),(12-737,i-Pro,J-3,O,S,O,2-Adm,H),(12-738,i-Pro,J-4,O,S,O,2-Adm,H),(12-739,i-Pro,J-5,O,S,O,2-Adm,H),(12-740,i-Pro,J-6,O,S,O,2-Adm,H),(12-741,i-Pro,J-7,O,S,O,2-Adm,H),(12-742,i-Pro,J-8,O,S,O,2-Adm,H),(12-743,i-Pro,J-9,O,S,O,2-Adm,H),(12-744,i-Pro,J-1,O,S,O,5-OH-2-Adm,H),(12-745,i-Pro,J-2,O,S,O,5-OH-2-Adm,H),(12-746,i-Pro,J-3,O,S,O,5-OH-2-Adm,H),(12-747,i-Pro,J-4,O,S,O,5-OH-2-Adm,H),(12-748,i-Pro,J-5,O,S,O,5-OH-2-Adm,H),(12-749,i-Pro,J-6,O,S,O,5-OH-2-Adm,H),(12-750,i-Pro,J-7,O,S,O,5-OH-2-Adm,H),(12-751,i-Pro,J-8,O,S,O,5-OH-2-Adm,H),(12-752,i-Pro,J-9,O,S,O,5-OH-2-Adm,H),(12-753,i-Pro,K-1,O,S,O,1-Adm,H),(12-754,i-Pro,K-2,O,S,O,1-Adm,H),(12-755,i-Pro,K-3,O,S,O,1-Adm,H),(12-756,i-Pro,K-4,O,S,O,1-Adm,H),(12-757,i-Pro,K-5,O,S,O,1-Adm,H),(12-758,i-Pro,K-6,O,S,O,1-Adm,H),(12-759,i-Pro,K-7,O,S,O,1-Adm,H),(12-760,i-Pro,K-8,O,S,O,1-Adm,H),(12-761,i-Pro,K-9,O,S,O,1-Adm,H),(12-762,i-Pro,K-1,O,S,O,2-Adm,H),(12-763,i-Pro,K-2,O,S,O,2-Adm,H),(12-764,i-Pro,K-3,O,S,O,2-Adm,H),(12-765,i-Pro,K-4,O,S,O,2-Adm,H),(12-766,i-Pro,K-5,O,S,O,2-Adm,H),(12-767,i-Pro,K-6,O,S,O,2-Adm,H),(12-768,i-Pro,K-7,O,S,O,2-Adm,H),(12-769,i-Pro,K-8,O,S,O,2-Adm,H),(12-770,i-Pro,K-9,O,S,O,2-Adm,H),(12-771,i-Pro,K-1,O,S,O,5-OH-2-Adm,H),(12-772,i-Pro,K-2,O,S,O,5-OH-2-Adm,H),(12-773,i-Pro,K-3,O,S,O,5-OH-2-Adm,H),(12-774,i-Pro,K-4,O,S,O,5-OH-2-Adm,H),(12-775,i-Pro,K-5,O,S,O,5-OH-2-Adm,H),(12-776,i-Pro,K-6,O,S,O,5-OH-2-Adm,H),(12-777,i-Pro,K-7,O,S,O,5-OH-2-Adm,H),(12-778,i-Pro,K-8,O,S,O,5-OH-2-Adm,H),(12-779,i-Pro,K-9,O,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(13-1,Pro,A-1,O,S,O,1-Adm,H),(13-2,Pro,A-2,O,S,O,1-Adm,H),(13-3,Pro,A-3,O,S,O,1-Adm,H),(13-4,Pro,A-4,O,S,O,1-Adm,H),(13-5,Pro,A-5,O,S,O,1-Adm,H),(13-6,Pro,A-6,O,S,O,1-Adm,H),(13-7,Pro,A-7,O,S,O,1-Adm,H),(13-8,Pro,A-8,O,S,O,1-Adm,H),(13-9,Pro,A-9,O,S,O,1-Adm,H),(13-11,Pro,A-11,O,S,O,1-Adm,H),(13-11,Pro,A-11,O,S,O,1-Adm,H),(13-12,Pro,A-12,O,S,O,1-Adm,H),(13-13,Pro,A-13,O,S,O,1-Adm,H),(13-14,Pro,A-14,O,S,O,1-Adm,H),(13-15,Pro,A-15,O,S,O,1-Adm,H),(13-16,Pro,A-16,O,S,O,1-Adm,H),(13-17,Pro,A-17,O,S,O,1-Adm,H),(13-18,Pro,A-18,O,S,O,1-Adm,H),(13-19,Pro,A-19,O,S,O,1-Adm,H),(13-20,Pro,A-20,O,S,O,1-Adm,H),(13-21,Pro,A-21,O,S,O,1-Adm,H),(13-22,Pro,A-22,O,S,O,1-Adm,H),(13-23,Pro,A-23,O,S,O,1-Adm,H),(13-24,Pro,A-24,O,S,O,1-Adm,H),(13-25,Pro,A-25,O,S,O,1-Adm,H),(13-26,Pro,A-26,O,S,O,1-Adm,H),(13-27,Pro,A-27,O,S,O,1-Adm,H),(13-28,Pro,A-28,O,S,O,1-Adm,H),(13-29,Pro,A-29,O,S,O,1-Adm,H),(13-30,Pro,A-30,O,S,O,1-Adm,H),(13-31,Pro,A-31,O,S,O,1-Adm,H),(13-32,Pro,A-32,O,S,O,1-Adm,H),(13-33,Pro,A-33,O,S,O,1-Adm,H),(13-34,Pro,A-34,O,S,O,1-Adm,H),(13-35,Pro,A-35,O,S,O,1-Adm,H),(13-36,Pro,A-36,O,S,O,1-Adm,H),(13-37,Pro,A-1,O,S,O,2-Adm,H),(13-38,Pro,A-2,O,S,O,2-Adm,H),(13-39,Pro,A-3,O,S,O,2-Adm,H),(13-40,Pro,A-4,O,S,O,2-Adm,H),(13-41,Pro,A-5,O,S,O,2-Adm,H),(13-42,Pro,A-6,O,S,O,2-Adm,H),(13-43,Pro,A-7,O,S,O,2-Adm,H),(13-44,Pro,A-9,O,S,O,2-Adm,H),(13-45,Pro,A-11,O,S,O,2-Adm,H),(13-46,Pro,A-12,O,S,O,2-Adm,H),(13-47,Pro,A-13,O,S,O,2-Adm,H),(13-48,Pro,A-14,O,S,O,2-Adm,H),(13-49,Pro,A-15,O,S,O,2-Adm,H),(13-50,Pro,A-16,O,S,O,2-Adm,H),(13-51,Pro,A-17,O,S,O,2-Adm,H),(13-52,Pro,A-18,O,S,O,2-Adm,H),(13-53,Pro,A-20,O,S,O,2-Adm,H),(13-54,Pro,A-21,O,S,O,2-Adm,H),(13-55,Pro,A-22,O,S,O,2-Adm,H),(13-56,Pro,A-23,O,S,O,2-Adm,H),(13-57,Pro,A-24,O,S,O,2-Adm,H),(13-58,Pro,A-26,O,S,O,2-Adm,H),(13-59,Pro,A-27,O,S,O,2-Adm,H),(13-60,Pro,A-28,O,S,O,2-Adm,H),(13-61,Pro,A-29,O,S,O,2-Adm,H),(13-62,Pro,A-30,O,S,O,2-Adm,H),(13-63,Pro,A-31,O,S,O,2-Adm,H),(13-64,Pro,A-32,O,S,O,2-Adm,H),(13-65,Pro,A-33,O,S,O,2-Adm,H),(13-66,Pro,A-34,O,S,O,2-Adm,H),(13-67,Pro,A-35,O,S,O,2-Adm,H),(13-68,Pro,A-36,O,S,O,2-Adm,H),(13-69,Pro,A-1,O,S,O,5-OH-2-Adm,H),(13-70,Pro,A-2,O,S,O,5-OH-2-Adm,H),(13-71,Pro,A-3,O,S,O,5-OH-2-Adm,H),(13-72,Pro,A-4,O,S,O,5-OH-2-Adm,H),(13-73,Pro,A-5,O,S,O,5-OH-2-Adm,H),(13-74,Pro,A-6,O,S,O,5-OH-2-Adm,H),(13-75,Pro,A-7,O,S,O,5-OH-2-Adm,H),(13-76,Pro,A-8,O,S,O,5-OH-2-Adm,H),(13-77,Pro,A-9,O,S,O,5-OH-2-Adm,H),(13-78,Pro,A-10,O,S,O,5-OH-2-Adm,H),(13-79,Pro,A-11,O,S,O,5-OH-2-Adm,H),(13-80,Pro,A-12,O,S,O,5-OH-2-Adm,H),(13-81,Pro,A-13,O,S,O,5-OH-2-Adm,H),(13-82,Pro,A-14,O,S,O,5-OH-2-Adm,H),(13-83,Pro,A-15,O,S,O,5-OH-2-Adm,H),(13-84,Pro,A-16,O,S,O,5-OH-2-Adm,H),(13-85,Pro,A-17,O,S,O,5-OH-2-Adm,H),(13-86,Pro,A-18,O,S,O,5-OH-2-Adm,H),(13-87,Pro,A-19,O,S,O,5-OH-2-Adm,H),(13-88,Pro,A-20,O,S,O,5-OH-2-Adm,H),(13-89,Pro,A-21,O,S,O,5-OH-2-Adm,H),(13-90,Pro,A-22,O,S,O,5-OH-2-Adm,H),(13-91,Pro,A-23,O,S,O,5-OH-2-Adm,H),(13-92,Pro,A-24,O,S,O,5-OH-2-Adm,H),(13-93,Pro,A-25,O,S,O,5-OH-2-Adm,H),(13-94,Pro,A-26,O,S,O,5-OH-2-Adm,H),(13-95,Pro,A-27,O,S,O,5-OH-2-Adm,H),(13-96,Pro,A-28,O,S,O,5-OH-2-Adm,H),(13-97,Pro,A-29,O,S,O,5-OH-2-Adm,H),(13-98,Pro,A-30,O,S,O,5-OH-2-Adm,H),(13-99,Pro,A-31,O,S,O,5-OH-2-Adm,H),(13-100,Pro,A-32,O,S,O,5-OH-2-Adm,H),(13-101,Pro,A-33,O,S,O,5-OH-2-Adm,H),(13-102,Pro,A-34,O,S,O,5-OH-2-Adm,H),(13-103,Pro,A-35,O,S,O,5-OH-2-Adm,H),(13-104,Pro,A-36,O,S,O,5-OH-2-Adm,H),(13-105,Pro,B-1,O,S,O,1-Adm,H),(13-106,Pro,B-2,O,S,O,1-Adm,H),(13-107,Pro,B-3,O,S,O,1-Adm,H),(13-108,Pro,B-4,O,S,O,1-Adm,H),(13-109,Pro,B-5,O,S,O,1-Adm,H),(13-110,Pro,B-6,O,S,O,1-Adm,H),(13-111,Pro,B-7,O,S,O,1-Adm,H),(13-112,Pro,B-8,O,S,O,1-Adm,H),(13-113,Pro,B-9,O,S,O,1-Adm,H),(13-114,Pro,B-11,O,S,O,1-Adm,H),(13-115,Pro,B-11,O,S,O,1-Adm,H),(13-116,Pro,B-12,O,S,O,1-Adm,H),(13-117,Pro,B-13,O,S,O,1-Adm,H),(13-118,Pro,B-14,O,S,O,1-Adm,H),(13-119,Pro,B-15,O,S,O,1-Adm,H),(13-120,Pro,B-16,O,S,O,1-Adm,H),(13-121,Pro,B-17,O,S,O,1-Adm,H),(13-122,Pro,B-18,O,S,O,1-Adm,H),(13-123,Pro,B-19,O,S,O,1-Adm,H),(13-124,Pro,B-20,O,S,O,1-Adm,H),(13-125,Pro,B-21,O,S,O,1-Adm,H),(13-126,Pro,B-22,O,S,O,1-Adm,H),(13-127,Pro,B-23,O,S,O,1-Adm,H),(13-128,Pro,B-24,O,S,O,1-Adm,H),(13-129,Pro,B-25,O,S,O,1-Adm,H),(13-130,Pro,B-26,O,S,O,1-Adm,H),(13-131,Pro,B-27,O,S,O,1-Adm,H),(13-132,Pro,B-28,O,S,O,1-Adm,H),(13-133,Pro,B-29,O,S,O,1-Adm,H),(13-134,Pro,B-30,O,S,O,1-Adm,H),(13-135,Pro,B-31,O,S,O,1-Adm,H),(13-136,Pro,B-32,O,S,O,1-Adm,H),(13-137,Pro,B-33,O,S,O,1-Adm,H),(13-138,Pro,B-34,O,S,O,1-Adm,H),(13-139,Pro,B-35,O,S,O,1-Adm,H),(13-140,Pro,B-36,O,S,O,1-Adm,H),(13-141,Pro,B-1,O,S,O,2-Adm,H),(13-142,Pro,B-2,O,S,O,2-Adm,H),(13-143,Pro,B-3,O,S,O,2-Adm,H),(13-144,Pro,B-4,O,S,O,2-Adm,H),(13-145,Pro,B-5,O,S,O,2-Adm,H),(13-146,Pro,B-6,O,S,O,2-Adm,H),(13-147,Pro,B-7,O,S,O,2-Adm,H),(13-148,Pro,B-8,O,S,O,2-Adm,H),(13-149,Pro,B-9,O,S,O,2-Adm,H),(13-150,Pro,B-10,O,S,O,2-Adm,H),(13-151,Pro,B-11,O,S,O,2-Adm,H),(13-152,Pro,B-12,O,S,O,2-Adm,H),(13-153,Pro,B-13,O,S,O,2-Adm,H),(13-154,Pro,B-14,O,S,O,2-Adm,H),(13-155,Pro,B-15,O,S,O,2-Adm,H),(13-156,Pro,B-16,O,S,O,2-Adm,H),(13-157,Pro,B-17,O,S,O,2-Adm,H),(13-158,Pro,B-18,O,S,O,2-Adm,H),(13-159,Pro,B-19,O,S,O,2-Adm,H),(13-160,Pro,B-20,O,S,O,2-Adm,H),(13-161,Pro,B-21,O,S,O,2-Adm,H),(13-162,Pro,B-22,O,S,O,2-Adm,H),(13-163,Pro,B-23,O,S,O,2-Adm,H),(13-164,Pro,B-24,O,S,O,2-Adm,H),(13-165,Pro,B-25,O,S,O,2-Adm,H),(13-166,Pro,B-26,O,S,O,2-Adm,H),(13-167,Pro,B-27,O,S,O,2-Adm,H),(13-168,Pro,B-28,O,S,O,2-Adm,H),(13-169,Pro,B-29,O,S,O,2-Adm,H),(13-170,Pro,B-30,O,S,O,2-Adm,H),(13-171,Pro,B-31,O,S,O,2-Adm,H),(13-172,Pro,B-32,O,S,O,2-Adm,H),(13-173,Pro,B-33,O,S,O,2-Adm,H),(13-174,Pro,B-34,O,S,O,2-Adm,H),(13-175,Pro,B-35,O,S,O,2-Adm,H),(13-176,Pro,B-36,O,S,O,2-Adm,H),(13-177,Pro,B-1,O,S,O,5-OH-2-Adm,H),(13-178,Pro,B-2,O,S,O,5-OH-2-Adm,H),(13-179,Pro,B-3,O,S,O,5-OH-2-Adm,H),(13-180,Pro,B-4,O,S,O,5-OH-2-Adm,H),(13-181,Pro,B-5,O,S,O,5-OH-2-Adm,H),(13-182,Pro,B-6,O,S,O,5-OH-2-Adm,H),(13-183,Pro,B-7,O,S,O,5-OH-2-Adm,H),(13-184,Pro,B-8,O,S,O,5-OH-2-Adm,H),(13-185,Pro,B-9,O,S,O,5-OH-2-Adm,H),(13-186,Pro,B-10,O,S,O,5-OH-2-Adm,H),(13-187,Pro,B-11,O,S,O,5-OH-2-Adm,H),(13-188,Pro,B-12,O,S,O,5-OH-2-Adm,H),(13-189,Pro,B-13,O,S,O,5-OH-2-Adm,H),(13-190,Pro,B-14,O,S,O,5-OH-2-Adm,H),(13-191,Pro,B-15,O,S,O,5-OH-2-Adm,H),(13-192,Pro,B-16,O,S,O,5-OH-2-Adm,H),(13-193,Pro,B-17,O,S,O,5-OH-2-Adm,H),(13-194,Pro,B-18,O,S,O,5-OH-2-Adm,H),(13-195,Pro,B-19,O,S,O,5-OH-2-Adm,H),(13-196,Pro,B-20,O,S,O,5-OH-2-Adm,H),(13-197,Pro,B-21,O,S,O,5-OH-2-Adm,H),(13-198,Pro,B-22,O,S,O,5-OH-2-Adm,H),(13-199,Pro,B-23,O,S,O,5-OH-2-Adm,H),(13-200,Pro,B-24,O,S,O,5-OH-2-Adm,H),(13-201,Pro,B-25,O,S,O,5-OH-2-Adm,H),(13-202,Pro,B-26,O,S,O,5-OH-2-Adm,H),(13-203,Pro,B-27,O,S,O,5-OH-2-Adm,H),(13-204,Pro,B-28,O,S,O,5-OH-2-Adm,H),(13-205,Pro,B-29,O,S,O,5-OH-2-Adm,H),(13-206,Pro,B-30,O,S,O,5-OH-2-Adm,H),(13-207,Pro,B-31,O,S,O,5-OH-2-Adm,H),(13-208,Pro,B-32,O,S,O,5-OH-2-Adm,H),(13-209,Pro,B-33,O,S,O,5-OH-2-Adm,H),(13-210,Pro,B-34,O,S,O,5-OH-2-Adm,H),(13-211,Pro,B-35,O,S,O,5-OH-2-Adm,H),(13-212,Pro,B-36,O,S,O,5-OH-2-Adm,H),(13-213,Pro,C-1,O,S,O,1-Adm,H),(13-214,Pro,C-2,O,S,O,1-Adm,H),(13-215,Pro,C-3,O,S,O,1-Adm,H),(13-216,Pro,C-4,O,S,O,1-Adm,H),(13-217,Pro,C-5,O,S,O,1-Adm,H),(13-218,Pro,C-6,O,S,O,1-Adm,H),(13-219,Pro,C-7,O,S,O,1-Adm,H),(13-220,Pro,C-8,O,S,O,1-Adm,H),(13-221,Pro,C-9,O,S,O,1-Adm,H),(13-222,Pro,C-1,O,S,O,1-Adm,H),(13-223,Pro,C-11,O,S,O,1-Adm,H),(13-224,Pro,C-12,O,S,O,1-Adm,H),(13-225,Pro,C-13,O,S,O,1-Adm,H),(13-226,Pro,C-14,O,S,O,1-Adm,H),(13-227,Pro,C-15,O,S,O,1-Adm,H),(13-228,Pro,C-16,O,S,O,1-Adm,H),(13-229,Pro,C-17,O,S,O,1-Adm,H),(13-230,Pro,C-18,O,S,O,1-Adm,H),(13-231,Pro,C-19,O,S,O,1-Adm,H),(13-232,Pro,C-20,O,S,O,1-Adm,H),(13-233,Pro,C-21,O,S,O,1-Adm,H),(13-234,Pro,C-22,O,S,O,1-Adm,H),(13-235,Pro,C-23,O,S,O,1-Adm,H),(13-236,Pro,C-24,O,S,O,1-Adm,H),(13-237,Pro,C-25,O,S,O,1-Adm,H),(13-238,Pro,C-26,O,S,O,1-Adm,H),(13-239,Pro,C-27,O,S,O,1-Adm,H),(13-240,Pro,C-28,O,S,O,1-Adm,H),(13-241,Pro,C-29,O,S,O,1-Adm,H),(13-242,Pro,C-30,O,S,O,1-Adm,H),(13-243,Pro,C-31,O,S,O,1-Adm,H),(13-244,Pro,C-32,O,S,O,1-Adm,H),(13-245,Pro,C-33,O,S,O,1-Adm,H),(13-246,Pro,C-34,O,S,O,1-Adm,H),(13-247,Pro,C-35,O,S,O,1-Adm,H),(13-248,Pro,C-36,O,S,O,1-Adm,H),(13-249,Pro,C-1,O,S,O,2-Adm,H),(13-250,Pro,C-2,O,S,O,2-Adm,H),(13-251,Pro,C-3,O,S,O,2-Adm,H),(13-252,Pro,C-4,O,S,O,2-Adm,H),(13-253,Pro,C-5,O,S,O,2-Adm,H),(13-254,Pro,C-6,O,S,O,2-Adm,H),(13-255,Pro,C-7,O,S,O,2-Adm,H),(13-256,Pro,C-8,O,S,O,2-Adm,H),(13-257,Pro,C-9,O,S,O,2-Adm,H),(13-258,Pro,C-10,O,S,O,2-Adm,H),(13-259,Pro,C-11,O,S,O,2-Adm,H),(13-260,Pro,C-12,O,S,O,2-Adm,H),(13-261,Pro,C-13,O,S,O,2-Adm,H),(13-262,Pro,C-14,O,S,O,2-Adm,H),(13-263,Pro,C-15,O,S,O,2-Adm,H),(13-264,Pro,C-16,O,S,O,2-Adm,H),(13-265,Pro,C-17,O,S,O,2-Adm,H),(13-266,Pro,C-18,O,S,O,2-Adm,H),(13-267,Pro,C-19,O,S,O,2-Adm,H),(13-268,Pro,C-20,O,S,O,2-Adm,H),(13-269,Pro,C-21,O,S,O,2-Adm,H),(13-270,Pro,C-22,O,S,O,2-Adm,H),(13-271,Pro,C-23,O,S,O,2-Adm,H),(13-272,Pro,C-24,O,S,O,2-Adm,H),(13-273,Pro,C-25,O,S,O,2-Adm,H),(13-274,Pro,C-26,O,S,O,2-Adm,H),(13-275,Pro,C-27,O,S,O,2-Adm,H),(13-276,Pro,C-28,O,S,O,2-Adm,H),(13-277,Pro,C-29,O,S,O,2-Adm,H),(13-278,Pro,C-30,O,S,O,2-Adm,H),(13-279,Pro,C-31,O,S,O,2-Adm,H),(13-280,Pro,C-32,O,S,O,2-Adm,H),(13-281,Pro,C-33,O,S,O,2-Adm,H),(13-282,Pro,C-34,O,S,O,2-Adm,H),(13-283,Pro,C-35,O,S,O,2-Adm,H),(13-284,Pro,C-36,O,S,O,2-Adm,H),(13-285,Pro,C-1,O,S,O,5-OH-2-Adm,H),(13-286,Pro,C-2,O,S,O,5-OH-2-Adm,H),(13-287,Pro,C-3,O,S,O,5-OH-2-Adm,H),(13-288,Pro,C-4,O,S,O,5-OH-2-Adm,H),(13-289,Pro,C-5,O,S,O,5-OH-2-Adm,H),(13-290,Pro,C-6,O,S,O,5-OH-2-Adm,H),(13-291,Pro,C-7,O,S,O,5-OH-2-Adm,H),(13-292,Pro,C-8,O,S,O,5-OH-2-Adm,H),(13-293,Pro,C-9,O,S,O,5-OH-2-Adm,H),(13-294,Pro,C-10,O,S,O,5-OH-2-Adm,H),(13-295,Pro,C-11,O,S,O,5-OH-2-Adm,H),(13-296,Pro,C-12,O,S,O,5-OH-2-Adm,H),(13-297,Pro,C-13,O,S,O,5-OH-2-Adm,H),(13-298,Pro,C-14,O,S,O,5-OH-2-Adm,H),(13-299,Pro,C-15,O,S,O,5-OH-2-Adm,H),(13-300,Pro,C-16,O,S,O,5-OH-2-Adm,H),(13-301,Pro,C-17,O,S,O,5-OH-2-Adm,H),(13-302,Pro,C-18,O,S,O,5-OH-2-Adm,H),(13-303,Pro,C-19,O,S,O,5-OH-2-Adm,H),(13-304,Pro,C-2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,Pro,F-33,O,S,O,2-Adm,H),(13-606,Pro,F-34,O,S,O,2-Adm,H),(13-607,Pro,F-35,O,S,O,2-Adm,H),(13-608,Pro,F-36,O,S,O,2-Adm,H),(13-609,Pro,F-1,O,S,O,5-OH-2-Adm,H),(13-610,Pro,F-2,O,S,O,5-OH-2-Adm,H),(13-611,Pro,F-3,O,S,O,5-OH-2-Adm,H),(13-612,Pro,F-4,O,S,O,5-OH-2-Adm,H),(13-613,Pro,F-5,O,S,O,5-OH-2-Adm,H),(13-614,Pro,F-6,O,S,O,5-OH-2-Adm,H),(13-615,Pro,F-7,O,S,O,5-OH-2-Adm,H),(13-616,Pro,F-8,O,S,O,5-OH-2-Adm,H),(13-617,Pro,F-9,O,S,O,5-OH-2-Adm,H),(13-618,Pro,F-10,O,S,O,5-OH-2-Adm,H),(13-619,Pro,F-11,O,S,O,5-OH-2-Adm,H),(13-620,Pro,F-12,O,S,O,5-OH-2-Adm,H),(13-621,Pro,F-13,O,S,O,5-OH-2-Adm,H),(13-622,Pro,F-14,O,S,O,5-OH-2-Adm,H),(13-623,Pro,F-15,O,S,O,5-OH-2-Adm,H),(13-624,Pro,F-16,O,S,O,5-OH-2-Adm,H),(13-625,Pro,F-17,O,S,O,5-OH-2-Adm,H),(13-626,Pro,F-18,O,S,O,5-OH-2-Adm,H),(13-627,Pro,F-19,O,S,O,5-OH-2-Adm,H),(13-628,Pro,F-20,O,S,O,5-OH-2-Adm,H),(13-629,Pro,F-21,O,S,O,5-OH-2-Adm,H),(13-630,Pro,F-22,O,S,O,5-OH-2-Adm,H),(13-631,Pro,F-23,O,S,O,5-OH-2-Adm,H),(13-632,Pro,F-24,O,S,O,5-OH-2-Adm,H),(13-633,Pro,F-25,O,S,O,5-OH-2-Adm,H),(13-634,Pro,F-26,O,S,O,5-OH-2-Adm,H),(13-635,Pro,F-27,O,S,O,5-OH-2-Adm,H),(13-636,Pro,F-28,O,S,O,5-OH-2-Adm,H),(13-637,Pro,F-29,O,S,O,5-OH-2-Adm,H),(13-638,Pro,F-30,O,S,O,5-OH-2-Adm,H),(13-639,Pro,F-31,O,S,O,5-OH-2-Adm,H),(13-640,Pro,F-32,O,S,O,5-OH-2-Adm,H),(13-641,Pro,F-33,O,S,O,5-OH-2-Adm,H),(13-642,Pro,F-34,O,S,O,5-OH-2-Adm,H),(13-643,Pro,F-35,O,S,O,5-OH-2-Adm,H),(13-644,Pro,F-36,O,S,O,5-OH-2-Adm,H),(13-645,Pro,G-1,O,S,O,1-Adm,H),(13-646,Pro,G-2,O,S,O,1-Adm,H),(13-647,Pro,G-3,O,S,O,1-Adm,H),(13-648,Pro,G-4,O,S,O,1-Adm,H),(13-649,Pro,G-5,O,S,O,1-Adm,H),(13-650,Pro,G-6,O,S,O,1-Adm,H),(13-651,Pro,G-7,O,S,O,1-Adm,H),(13-652,Pro,G-8,O,S,O,1-Adm,H),(13-653,Pro,G-9,O,S,O,1-Adm,H),(13-654,Pro,G-1,O,S,O,2-Adm,H),(13-655,Pro,G-2,O,S,O,2-Adm,H),(13-656,Pro,G-3,O,S,O,2-Adm,H),(13-657,Pro,G-4,O,S,O,2-Adm,H),(13-658,Pro,G-5,O,S,O,2-Adm,H),(13-659,Pro,G-6,O,S,O,2-Adm,H),(13-660,Pro,G-7,O,S,O,2-Adm,H),(13-661,Pro,G-8,O,S,O,2-Adm,H),(13-662,Pro,G-9,O,S,O,2-Adm,H),(13-663,Pro,G-1,O,S,O,5-OH-2-Adm,H),(13-664,Pro,G-2,O,S,O,5-OH-2-Adm,H),(13-665,Pro,G-3,O,S,O,5-OH-2-Adm,H),(13-666,Pro,G-4,O,S,O,5-OH-2-Adm,H),(13-667,Pro,G-5,O,S,O,5-OH-2-Adm,H),(13-668,Pro,G-6,O,S,O,5-OH-2-Adm,H),(13-669,Pro,G-7,O,S,O,5-OH-2-Adm,H),(13-670,Pro,G-8,O,S,O,5-OH-2-Adm,H),(13-671,Pro,G-9,O,S,O,5-OH-2-Adm,H),(13-672,Pro,H-1,O,S,O,1-Adm,H),(13-673,Pro,H-2,O,S,O,1-Adm,H),(13-674,Pro,H-3,O,S,O,1-Adm,H),(13-675,Pro,H-4,O,S,O,1-Adm,H),(13-676,Pro,H-5,O,S,O,1-Adm,H),(13-677,Pro,H-6,O,S,O,1-Adm,H),(13-678,Pro,H-7,O,S,O,1-Adm,H),(13-679,Pro,H-8,O,S,O,1-Adm,H),(13-680,Pro,H-9,O,S,O,1-Adm,H),(13-681,Pro,H-1,O,S,O,2-Adm,H),(13-682,Pro,H-2,O,S,O,2-Adm,H),(13-683,Pro,H-3,O,S,O,2-Adm,H),(13-684,Pro,H-4,O,S,O,2-Adm,H),(13-685,Pro,H-5,O,S,O,2-Adm,H),(13-686,Pro,H-6,O,S,O,2-Adm,H),(13-687,Pro,H-7,O,S,O,2-Adm,H),(13-688,Pro,H-8,O,S,O,2-Adm,H),(13-689,Pro,H-9,O,S,O,2-Adm,H),(13-690,Pro,H-1,O,S,O,5-OH-2-Adm,H),(13-691,Pro,H-2,O,S,O,5-OH-2-Adm,H),(13-692,Pro,H-3,O,S,O,5-OH-2-Adm,H),(13-693,Pro,H-4,O,S,O,5-OH-2-Adm,H),(13-694,Pro,H-5,O,S,O,5-OH-2-Adm,H),(13-695,Pro,H-6,O,S,O,5-OH-2-Adm,H),(13-696,Pro,H-7,O,S,O,5-OH-2-Adm,H),(13-697,Pro,H-8,O,S,O,5-OH-2-Adm,H),(13-698,Pro,H-9,O,S,O,5-OH-2-Adm,H),(13-699,Pro,I-1,O,S,O,1-Adm,H),(13-700,Pro,I-2,O,S,O,1-Adm,H),(13-701,Pro,I-3,O,S,O,1-Adm,H),(13-702,Pro,I-4,O,S,O,1-Adm,H),(13-703,Pro,I-5,O,S,O,1-Adm,H),(13-704,Pro,I-6,O,S,O,1-Adm,H),(13-705,Pro,I-7,O,S,O,1-Adm,H),(13-706,Pro,I-8,O,S,O,1-Adm,H),(13-707,Pro,I-9,O,S,O,1-Adm,H),(13-708,Pro,I-1,O,S,O,2-Adm,H),(13-709,Pro,I-2,O,S,O,2-Adm,H),(13-710,Pro,I-3,O,S,O,2-Adm,H),(13-711,Pro,I-4,O,S,O,2-Adm,H),(13-712,Pro,I-5,O,S,O,2-Adm,H),(13-713,Pro,I-6,O,S,O,2-Adm,H),(13-714,Pro,I-7,O,S,O,2-Adm,H),(13-715,Pro,I-8,O,S,O,2-Adm,H),(13-716,Pro,I-9,O,S,O,2-Adm,H),(13-717,Pro,I-1,O,S,O,5-OH-2-Adm,H),(13-718,Pro,I-2,O,S,O,5-OH-2-Adm,H),(13-719,Pro,I-3,O,S,O,5-OH-2-Adm,H),(13-720,Pro,I-4,O,S,O,5-OH-2-Adm,H),(13-721,Pro,I-5,O,S,O,5-OH-2-Adm,H),(13-722,Pro,I-6,O,S,O,5-OH-2-Adm,H),(13-723,Pro,I-7,O,S,O,5-OH-2-Adm,H),(13-724,Pro,I-8,O,S,O,5-OH-2-Adm,H),(13-725,Pro,I-9,O,S,O,5-OH-2-Adm,H),(13-726,Pro,J-1,O,S,O,1-Adm,H),(13-727,Pro,J-2,O,S,O,1-Adm,H),(13-728,Pro,J-3,O,S,O,1-Adm,H),(13-729,Pro,J-4,O,S,O,1-Adm,H),(13-730,Pro,J-5,O,S,O,1-Adm,H),(13-731,Pro,J-6,O,S,O,1-Adm,H),(13-732,Pro,J-7,O,S,O,1-Adm,H),(13-733,Pro,J-8,O,S,O,1-Adm,H),(13-734,Pro,J-9,O,S,O,1-Adm,H),(13-735,Pro,J-1,O,S,O,2-Adm,H),(13-736,Pro,J-2,O,S,O,2-Adm,H),(13-737,Pro,J-3,O,S,O,2-Adm,H),(13-738,Pro,J-4,O,S,O,2-Adm,H),(13-739,Pro,J-5,O,S,O,2-Adm,H),(13-740,Pro,J-6,O,S,O,2-Adm,H),(13-741,Pro,J-7,O,S,O,2-Adm,H),(13-742,Pro,J-8,O,S,O,2-Adm,H),(13-743,Pro,J-9,O,S,O,2-Adm,H),(13-744,Pro,J-1,O,S,O,5-OH-2-Adm,H),(13-745,Pro,J-2,O,S,O,5-OH-2-Adm,H),(13-746,Pro,J-3,O,S,O,5-OH-2-Adm,H),(13-747,Pro,J-4,O,S,O,5-OH-2-Adm,H),(13-748,Pro,J-5,O,S,O,5-OH-2-Adm,H),(13-749,Pro,J-6,O,S,O,5-OH-2-Adm,H),(13-750,Pro,J-7,O,S,O,5-OH-2-Adm,H),(13-751,Pro,J-8,O,S,O,5-OH-2-Adm,H),(13-752,Pro,J-9,O,S,O,5-OH-2-Adm,H),(13-753,Pro,K-1,O,S,O,1-Adm,H),(13-754,Pro,K-2,O,S,O,1-Adm,H),(13-755,Pro,K-3,O,S,O,1-Adm,H),(13-756,Pro,K-4,O,S,O,1-Adm,H),(13-757,Pro,K-5,O,S,O,1-Adm,H),(13-758,Pro,K-6,O,S,O,1-Adm,H),(13-759,Pro,K-7,O,S,O,1-Adm,H),(13-760,Pro,K-8,O,S,O,1-Adm,H),(13-761,Pro,K-9,O,S,O,1-Adm,H),(13-762,Pro,K-1,O,S,O,2-Adm,H),(13-763,Pro,K-2,O,S,O,2-Adm,H),(13-764,Pro,K-3,O,S,O,2-Adm,H),(13-765,Pro,K-4,O,S,O,2-Adm,H),(13-766,Pro,K-5,O,S,O,2-Adm,H),(13-767,Pro,K-6,O,S,O,2-Adm,H),(13-768,Pro,K-7,O,S,O,2-Adm,H),(13-769,Pro,K-8,O,S,O,2-Adm,H),(13-770,Pro,K-9,O,S,O,2-Adm,H),(13-771,Pro,K-1,O,S,O,5-OH-2-Adm,H),(13-772,Pro,K-2,O,S,O,5-OH-2-Adm,H),(13-773,Pro,K-3,O,S,O,5-OH-2-Adm,H),(13-774,Pro,K-4,O,S,O,5-OH-2-Adm,H),(13-775,Pro,K-5,O,S,O,5-OH-2-Adm,H),(13-776,Pro,K-6,O,S,O,5-OH-2-Adm,H),(13-777,Pro,K-7,O,S,O,5-OH-2-Adm,H),(13-778,Pro,K-8,O,S,O,5-OH-2-Adm,H),(13-779,Pro,K-9,O,S,O,5-OH-2-Adm,H)

(Compound No.,R²,R³,X,Y,Z,R⁴,R⁵)=(14-1,Et,A-1,O,S,O,1-Adm,H),(14-2,Et,A-2,O,S,O,1-Adm,H),(14-3,Et,A-3,O,S,O,1-Adm,H),(14-4,Et,A-4,O,S,O,1-Adm,H),(14-5,Et,A-5,O,S,O,1-Adm,H),(14-6,Et,A-6,O,S,O,1-Adm,H),(14-7,Et,A-7,O,S,O,1-Adm,H),(14-8,Et,A-8,O,S,O,1-Adm,H),(14-9,Et,A-9,O,S,O,1-Adm,H),(14-11,Et,A-11,O,S,O,1-Adm,H),(14-11,Et,A-1,O,S,O,1-Adm,H),(14-12,Et,A-12,O,S,O,1-Adm,H),(14-13,Et,A-13,O,S,O,1-Adm,H),(14-14,Et,A-14,O,S,O,1-Adm,H),(14-15,Et,A-15,O,S,O,1-Adm,H),(14-16,Et,A-16,O,S,O,1-Adm,H),(14-17,Et,A-17,O,S,O,1-Adm,H),(14-18,Et,A-18,O,S,O,1-Adm,H),(14-19,Et,A-19,O,S,O,1-Adm,H),(14-20,Et,A-20,O,S,O,1-Adm,H),(14-21,Et,A-21,O,S,O,1-Adm,H),(14-22,Et,A-22,O,S,O,1-Adm,H),(14-23,Et,A-23,O,S,O,1-Adm,H),(14-24,Et,A-24,O,S,O,1-Adm,H),(14-25,Et,A-25,O,S,O,1-Adm,H),(14-26,Et,A-26,O,S,O,1-Adm,H),(14-27,Et,A-27,O,S,O,1-Adm,H),(14-28,Et,A-28,O,S,O,1-Adm,H),(14-29,Et,A-29,O,S,O,1-Adm,H),(14-30,Et,A-30,O,S,O,1-Adm,H),(14-31,Et,A-31,O,S,O,1-Adm,H),(14-32,Et,A-32,O,S,O,1-Adm,H),(14-33,Et,A-33,O,S,O,1-Adm,H),(14-34,Et,A-34,O,S,O,1-Adm,H),(14-35,Et,A-35,O,S,O,1-Adm,H),(14-36,Et,A-36,O,S,O,1-Adm,H),(14-37,Et,A-1,O,S,O,2-Adm,H),(14-38,Et,A-2,O,S,O,2-Adm,H),(14-39,Et,A-3,O,S,O,2-Adm,H),(14-40,Et,A-4,O,S,O,2-Adm,H),(14-41,Et,A-5,O,S,O,2-Adm,H),(14-42,Et,A-6,O,S,O,2-Adm,H),(14-43,Et,A-7,O,S,O,2-Adm,H),(14-44,Et,A-8,O,S,O,2-Adm,H),(14-45,Et,A-9,O,S,O,2-Adm,H),(14-46,Et,A-10,O,S,O,2-Adm,H),(14-47,Et,A-11,O,S,O,2-Adm,H),(14-48,Et,A-12,O,S,O,2-Adm,H),(14-49,Et,A-13,O,S,O,2-Adm,H),(14-50,Et,A-14,O,S,O,2-Adm,H),(14-51,Et,A-15,O,S,O,2-Adm,H),(14-52,Et,A-16,O,S,O,2-Adm,H),(14-53,Et,A-17,O,S,O,2-Adm,H),(14-54,Et,A-18,O,S,O,2-Adm,H),(14-55,Et,A-19,O,S,O,2-Adm,H),(14-56,Et,A-20,O,S,O,2-Adm,H),(14-57,Et,A-21,O,S,O,2-Adm,H),(14-58,Et,A-22,O,S,O,2-Adm,H),(14-59,Et,A-23,O,S,O,2-Adm,H),(14-60,Et,A-24,O,S,O,2-Adm,H),(14-61,Et,A-25,O,S,O,2-Adm,H),(14-62,Et,A-26,O,S,O,2-Adm,H),(14-63,Et,A-27,O,S,O,2-Adm,H),(14-64,Et,A-28,O,S,O,2-Adm,H),(14-65,Et,A-29,O,S,O,2-Adm,H),(14-66,Et,A-30,O,S,O,2-Adm,H),(14-67,Et,A-31,O,S,O,2-Adm,H),(14-68,Et,A-32,O,S,O,2-Adm,H),(14-69,Et,A-33,O,S,O,2-Adm,H),(14-70,Et,A-34,O,S,O,2-Adm,H),(14-71,Et,A-35,O,S,O,2-Adm,H),(14-72,Et,A-36,O,S,O,2-Adm,H),(14-73,Et,A-1,O,S,O,5-OH-2-Adm,H),(14-74,Et,A-2,O,S,O,5-OH-2-Adm,H),(14-75,Et,A-3,O,S,O,5-OH-2-Adm,H),(14-76,Et,A-4,O,S,O,5-OH-2-Adm,H),(14-77,Et,A-5,O,S,O,5-OH-2-Adm,H),(14-78,Et,A-6,O,S,O,5-OH-2-Adm,H),(14-79,Et,A-7,O,S,O,5-OH-2-Adm,H),(14-80,Et,A-8,O,S,O,5-OH-2-Adm,H),(14-81,Et,A-9,O,S,O,5-OH-2-Adm,H),(14-82,Et,A-10,O,S,O,5-OH-2-Adm,H),(14-83,Et,A-11,O,S,O,5-OH-2-Adm,H),(14-84,Et,A-12,O,S,O,5-OH-2-Adm,H),(14-85,Et,A-13,O,S,O,5-OH-2-Adm,H),(14-86,Et,A-14,O,S,O,5-OH-2-Adm,H),(14-87,Et,A-15,O,S,O,5-OH-2-Adm,H),(14-88,Et,A-16,O,S,O,5-OH-2-Adm,H),(14-89,Et,A-17,O,S,O,5-OH-2-Adm,H),(14-90,Et,A-18,O,S,O,5-OH-2-Adm,H),(14-91,Et,A-19,O,S,O,5-OH-2-Adm,H),(14-92,Et,A-20,O,S,O,5-OH-2-Adm,H),(14-93,Et,A-21,O,S,O,5-OH-2-Adm,H),(14-94,Et,A-22,O,S,O,5-OH-2-Adm,H),(14-95,Et,A-23,O,S,O,5-OH-2-Adm,H),(14-96,Et,A-24,O,S,O,5-OH-2-Adm,H),(14-97,Et,A-25,O,S,O,5-OH-2-Adm,H),(14-98,Et,A-26,O,S,O,5-OH-2-Adm,H),(14-99,Et,A-27,O,S,O,5-OH-2-Adm,H),(14-100,Et,A-28,O,S,O,5-OH-2-Adm,H),(14-101,Et,A-29,O,S,O,5-OH-2-Adm,H),(14-102,Et,A-30,O,S,O,5-OH-2-Adm,H),(14-103,Et,A-31,O,S,O,5-OH-2-Adm,H),(14-104,Et,A-32,O,S,O,5-OH-2-Adm,H),(14-105,Et,A-33,O,S,O,5-OH-2-Adm,H),(14-106,Et,A-34,O,S,O,5-OH-2-Adm,H),(14-107,Et,A-35,O,S,O,5-OH-2-Adm,H),(14-108,Et,A-36,O,S,O,5-OH-2-Adm,H),(14-119,Et,B-1,O,S,O,1-Adm,H),(14-111,Et,B-2,O,S,O,1-Adm,H),(14-111,Et,B-3,O,S,O,1-Adm,H),(14-112,Et,B-4,O,S,O,1-Adm,H),(14-113,Et,B-5,O,S,O,1-Adm,H),(14-114,Et,B-6,O,S,O,1-Adm,H),(14-115,Et,B-7,O,S,O,1-Adm,H),(14-116,Et,B-8,O,S,O,1-Adm,H),(14-117,Et,B-9,O,S,O,1-Adm,H),(14-118,Et,B-11,O,S,O,1-Adm,H),(14-119,Et,B-11,O,S,O,1-Adm,H),(14-120,Et,B-12,O,S,O,1-Adm,H),(14-121,Et,B-13,O,S,O,1-Adm,H),(14-122,Et,B-14,O,S,O,1-Adm,H),(14-123,Et,B-15,O,S,O,1-Adm,H),(14-124,Et,B-16,O,S,O,1-Adm,H),(14-125,Et,B-17,O,S,O,1-Adm,H),(14-126,Et,B-18,O,S,O,1-Adm,H),(14-127,Et,B-19,O,S,O,1-Adm,H),(14-128,Et,B-20,O,S,O,1-Adm,H),(14-129,Et,B-21,O,S,O,1-Adm,H),(14-130,Et,B-22,O,S,O,1-Adm,H),(14-131,Et,B-23,O,S,O,1-Adm,H),(14-132,Et,B-24,O,S,O,1-Adm,H),(14-133,Et,B-25,O,S,O,1-Adm,H),(14-134,Et,B-26,O,S,O,1-Adm,H),(14-135,Et,B-27,O,S,O,1-Adm,H),(14-136,Et,B-28,O,S,O,1-Adm,H),(14-137,Et,B-29,O,S,O,1-Adm,H),(14-138,Et,B-30,O,S,O,1-Adm,H),(14-139,Et,B-31,O,S,O,1-Adm,H),(14-140,Et,B-32,O,S,O,1-Adm,H),(14-141,Et,B-33,O,S,O,1-Adm,H),(14-142,Et,B-34,O,S,O,1-Adm,H),(14-143,Et,B-35,O,S,O,1-Adm,H),(14-144,Et,B-36,O,S,O,1-Adm,H),(14-145,Et,B-1,O,S,O,2-Adm,H),(14-146,Et,B-2,O,S,O,2-Adm,H),(14-147,Et,B-3,O,S,O,2-Adm,H),(14-148,Et,B-4,O,S,O,2-Adm,H),(14-149,Et,B-5,O,S,O,2-Adm,H),(14-150,Et,B-6,O,S,O,2-Adm,H),(14-151,Et,B-7,O,S,O,2-Adm,H),(14-152,Et,B-8,O,S,O,2-Adm,H),(14-153,Et,B-9,O,S,O,2-Adm,H),(14-154,Et,B-10,O,S,O,2-Adm,H),(14-155,Et,B-11,O,S,O,2-Adm,H),(14-156,Et,B-12,O,S,O,2-Adm,H),(14-157,Et,B-13,O,S,O,2-Adm,H),(14-158,Et,B-14,O,S,O,2-Adm,H),(14-159,Et,B-15,O,S,O,2-Adm,H),(14-160,Et,B-16,O,S,O,2-Adm,H),(14-161,Et,B-17,O,S,O,2-Adm,H),(14-162,Et,B-18,O,S,O,2-Adm,H),(14-163,Et,B-19,O,S,O,2-Adm,H),(14-164,Et,B-20,O,S,O,2-Adm,H),(14-165,Et,B-21,O,S,O,2-Adm,H),(14-166,Et,B-22,O,S,O,2-Adm,H),(14-167,Et,B-23,O,S,O,2-Adm,H),(14-168,Et,B-24,O,S,O,2-Adm,H),(14-169,Et,B-25,O,S,O,2-Adm,H),(14-170,Et,B-26,O,S,O,2-Adm,H),(14-171,Et,B-27,O,S,O,2-Adm,H),(14-172,Et,B-28,O,S,O,2-Adm,H),(14-173,Et,B-29,O,S,O,2-Adm,H),(14-174,Et,B-30,O,S,O,2-Adm,H),(14-175,Et,B-31,O,S,O,2-Adm,H),(14-176,Et,B-32,O,S,O,2-Adm,H),(14-177,Et,B-33,O,S,O,2-Adm,H),(14-178,Et,B-34,O,S,O,2-Adm,H),(14-179,Et,B-35,O,S,O,2-Adm,H),(14-180,Et,B-36,O,S,O,2-Adm,H),(14-181,Et,B-1,O,S,O,5-OH-2-Adm,H),(14-182,Et,B-2,O,S,O,5-OH-2-Adm,H),(14-183,Et,B-3,O,S,O,5-OH-2-Adm,H),(14-184,Et,B-4,O,S,O,5-OH-2-Adm,H),(14-185,Et,B-5,O,S,O,5-OH-2-Adm,H),(14-186,Et,B-6,O,S,O,5-OH-2-Adm,H),(14-187,Et,B-7,O,S,O,5-OH-2-Adm,H),(14-188,Et,B-8,O,S,O,5-OH-2-Adm,H),(14-189,Et,B-9,O,S,O,5-OH-2-Adm,H),(14-190,Et,B-10,O,S,O,5-OH-2-Adm,H),(14-191,Et,B-11,O,S,O,5-OH-2-Adm,H),(14-192,Et,B-12,O,S,O,5-OH-2-Adm,H),(14-193,Et,B-13,O,S,O,5-OH-2-Adm,H),(14-194,Et,B-14,O,S,O,5-OH-2-Adm,H),(14-195,Et,B-15,O,S,O,5-OH-2-Adm,H),(14-196,Et,B-16,O,S,O,5-OH-2-Adm,H),(14-197,Et,B-17,O,S,O,5-OH-2-Adm,H),(14-198,Et,B-18,O,S,O,5-OH-2-Adm,H),(14-199,Et,B-19,O,S,O,5-OH-2-Adm,H),(14-200,Et,B-20,O,S,O,5-OH-2-Adm,H),(14-201,Et,B-21,O,S,O,5-OH-2-Adm,H),(14-202,Et,B-22,O,S,O,5-OH-2-Adm,H),(14-203,Et,B-23,O,S,O,5-OH-2-Adm,H),(14-204,Et,B-24,O,S,O,5-OH-2-Adm,H),(14-205,Et,B-25,O,S,O,5-OH-2-Adm,H),(14-206,Et,B-26,O,S,O,5-OH-2-Adm,H),(14-207,Et,B-27,O,S,O,5-OH-2-Adm,H),(14-208,Et,B-28,O,S,O,5-OH-2-Adm,H),(14-209,Et,B-29,O,S,O,5-OH-2-Adm,H),(14-210,Et,B-30,O,S,O,5-OH-2-Adm,H),(14-211,Et,B-31,O,S,O,5-OH-2-Adm,H),(14-212,Et,B-32,O,S,O,5-OH-2-Adm,H),(14-213,Et,B-33,O,S,O,5-OH-2-Adm,H),(14-214,Et,B-34,O,S,O,5-OH-2-Adm,H),(14-215,Et,B-35,O,S,O,5-OH-2-Adm,H),(14-216,Et,B-36,O,S,O,5-OH-2-Adm,H),(14-217,Et,C-1,O,S,O,1-Adm,H),(14-218,Et,C-2,O,S,O,1-Adm,H),(14-219,Et,C-3,O,S,O,1-Adm,H),(14-220,Et,C-4,O,S,O,1-Adm,H),(14-221,Et,C-5,O,S,O,1-Adm,H),(14-222,Et,C-6,O,S,O,1-Adm,H),(14-223,Et,C-7,O,S,O,1-Adm,H),(14-224,Et,C-8,O,S,O,1-Adm,H),(14-225,Et,C-9,O,S,O,1-Adm,H),(14-226,Et,C-11,O,S,O,1-Adm,H),(14-227,Et,C-11,O,S,O,1-Adm,H),(14-228,Et,C-12,O,S,O,1-Adm,H),(14-229,Et,C-13,O,S,O,1-Adm,H),(14-230,Et,C-14,O,S,O,1-Adm,H),(14-231,Et,C-15,O,S,O,1-Adm,H),(14-232,Et,C-16,O,S,O,1-Adm,H),(14-233,Et,C-17,O,S,O,1-Adm,H),(14-234,Et,C-18,O,S,O,1-Adm,H),(14-235,Et,C-19,O,S,O,1-Adm,H),(14-236,Et,C-20,O,S,O,1-Adm,H),(14-237,Et,C-21,O,S,O,1-Adm,H),(14-238,Et,C-22,O,S,O,1-Adm,H),(14-239,Et,C-23,O,S,O,1-Adm,H),(14-240,Et,C-24,O,S,O,1-Adm,H),(14-241,Et,C-25,O,S,O,1-Adm,H),(14-242,Et,C-26,O,S,O,1-Adm,H),(14-243,Et,C-27,O,S,O,1-Adm,H),(14-244,Et,C-28,O,S,O,1-Adm,H),(14-245,Et,C-29,O,S,O,1-Adm,H),(14-246,Et,C-30,O,S,O,1-Adm,H),(14-247,Et,C-31,O,S,O,1-Adm,H),(14-248,Et,C-32,O,S,O,1-Adm,H),(14-249,Et,C-33,O,S,O,1-Adm,H),(14-250,Et,C-34,O,S,O,1-Adm,H),(14-251,Et,C-35,O,S,O,1-Adm,H),(14-252,Et,C-36,O,S,O,1-Adm,H),(14-253,Et,C-1,O,S,O,2-Adm,H),(14-254,Et,C-2,O,S,O,2-Adm,H),(14-255,Et,C-3,O,S,O,2-Adm,H),(14-256,Et,C-4,O,S,O,2-Adm,H),(14-257,Et,C-5,O,S,O,2-Adm,H),(14-258,Et,C-6,O,S,O,2-Adm,H),(14-259,Et,C-7,O,S,O,2-Adm,H),(14-260,Et,C-8,O,S,O,2-Adm,H),(14-261,Et,C-9,O,S,O,2-Adm,H),(14-262,Et,C-10,O,S,O,2-Adm,H),(14-263,Et,C-11,O,S,O,2-Adm,H),(14-264,Et,C-12,O,S,O,2-Adm,H),(14-265,Et,C-13,O,S,O,2-Adm,H),(14-266,Et,C-14,O,S,O,2-Adm,H),(14-267,Et,C-15,O,S,O,2-Adm,H),(14-268,Et,C-16,O,S,O,2-Adm,H),(14-269,Et,C-17,O,S,O,2-Adm,H),(14-270,Et,C-18,O,S,O,2-Adm,H),(14-271,Et,C-19,O,S,O,2-Adm,H),(14-272,Et,C-20,O,S,O,2-Adm,H),(14-273,Et,C-21,O,S,O,2-Adm,H),(14-274,Et,C-22,O,S,O,2-Adm,H),(14-275,Et,C-23,O,S,O,2-Adm,H),(14-276,Et,C-24,O,S,O,2-Adm,H),(14-277,Et,C-25,O,S,O,2-Adm,H),(14-278,Et,C-26,O,S,O,2-Adm,H),(14-279,Et,C-27,O,S,O,2-Adm,H),(14-280,Et,C-28,O,S,O,2-Adm,H),(14-281,Et,C-29,O,S,O,2-Adm,H),(14-282,Et,C-30,O,S,O,2-Adm,H),(14-283,Et,C-31,O,S,O,2-Adm,H),(14-284,Et,C-32,O,S,O,2-Adm,H),(14-285,Et,C-33,O,S,O,2-Adm,H),(14-286,Et,C-34,O,S,O,2-Adm,H),(14-287,Et,C-35,O,S,O,2-Adm,H),(14-288,Et,C-36,O,S,O,2-Adm,H),(14-289,Et,C-1,O,S,O,5-OH-2-Adm,H),(14-290,Et,C-2,O,S,O,5-OH-2-Adm,H),(14-291,Et,C-3,O,S,O,5-OH-2-Adm,H),(14-292,Et,C-4,O,S,O,5-OH-2-Adm,H),(14-293,Et,C-5,O,S,O,5-OH-2-Adm,H),(14-294,Et,C-6,O,S,O,5-OH-2-Adm,H),(14-295,Et,C-7,O,S,O,5-OH-2-Adm,H),(14-296,Et,C-8,O,S,O,5-OH-2-Adm,H),(14-297,Et,C-9,O,S,O,5-OH-2-Adm,H),(14-298,Et,C-10,O,S,O,5-OH-2-Adm,H),(14-299,Et,C-11,O,S,O,5-OH-2-Adm,H),(14-300,Et,C-12,O,S,O,5-OH-2-Adm,H),(14-301,Et,C-13,O,S,O,5-OH-2-Adm,H),(14-302,Et,C-14,O,S,O,5-OH-2-Adm,H),(14-303,Et,C-15,O,S,O,5-OH-2-Adm,H),(14-304,Et,C-16,O,S,O,5-OH-2-Adm,H),(14-305,Et,C-17,O,S,O,5-OH-2-Adm,H),(14-306,Et,C-18,O,S,O,5-OH-2-Adm,H),(14-307,Et,C-19,O,S,O,5-OH-2-Adm,H),(14-308,Et,C-20,O,S,O,5-OH-2-Adm,H),(14-309,Et,C-21,O,S,O,5-OH-2-Adm,H),(14-310,Et,C-22,O,S,O,5-OH-2-Adm,H),(14-311,Et,C-23,O,S,O,5-OH-2-Adm,H),(14-312,Et,C-24,O,S,O,5-OH-2-Adm,H),(14-313,Et,C-25,O,S,O,5-OH-2-Adm,H),(14-314,Et,C-26,O,S,O,5-OH-2-Adm,H),(14-315,Et,C-27,O,S,O,5-OH-2-Adm,H),(14-316,Et,C-28,O,S,O,5-OH-2-Adm,H),(14-317,Et,C-29,O,S,O,5-OH-2-Adm,H),(14-318,Et,C-30,O,S,O,5-OH-2-Adm,H),(14-319,Et,C-31,O,S,O,5-OH-2-Adm,H),(14-320,Et,C-32,O,S,O,5-OH-2-Adm,H),(14-321,Et,C-33,O,S,O,5-OH-2-Adm,H),(14-322,Et,C-34,O,S,O,5-OH-2-Adm,H),(14-323,Et,C-35,O,S,O,5-OH-2-Adm,H),(14-324,Et,C-36,O,S,O,5-OH-2-Adm,H),(14-325,Et,D-1,O,S,O,1-Adm,H),(14-326,Et,D-2,O,S,O,1-Adm,H),(14-327,Et,D-3,O,S,O,1-Adm,H),(14-328,Et,D-4,O,S,O,1-Adm,H),(14-329,Et,D-5,O,S,O,1-Adm,H),(14-330,Et,D-6,O,S,O,1-Adm,H),(14-331,Et,D-7,O,S,O,1-Adm,H),(14-332,Et,D-8,O,S,O,1-Adm,H),(14-333,Et,D-9,O,S,O,1-Adm,H),(14-334,Et,D-11,O,S,O,1-Adm,H),(14-335,Et,D-11,O,S,O,1-Adm,H),(14-336,Et,D-12,O,S,O,1-Adm,H),(14-337,Et,D-13,O,S,O,1-Adm,H),(14-338,Et,D-14,O,S,O,1-Adm,H),(14-339,Et,D-15,O,S,O,1-Adm,H),(14-340,Et,D-16,O,S,O,1-Adm,H),(14-341,Et,D-17,O,S,O,1-Adm,H),(14-342,Et,D-18,O,S,O,1-Adm,H),(14-343,Et,D-19,O,S,O,1-Adm,H),(14-344,Et,D-20,O,S,O,1-Adm,H),(14-345,Et,D-21,O,S,O,1-Adm,H),(14-346,Et,D-22,O,S,O,1-Adm,H),(14-347,Et,D-23,O,S,O,1-Adm,H),(14-348,Et,D-24,O,S,O,1-Adm,H),(14-349,Et,D-25,O,S,O,1-Adm,H),(14-350,Et,D-26,O,S,O,1-Adm,H),(14-351,Et,D-27,O,S,O,1-Adm,H),(14-352,Et,D-28,O,S,O,1-Adm,H),(14-353,Et,D-29,O,S,O,1-Adm,H),(14-354,Et,D-30,O,S,O,1-Adm,H),(14-355,Et,D-31,O,S,O,1-Adm,H),(14-356,Et,D-32,O,S,O,1-Adm,H),(14-357,Et,D-33,O,S,O,1-Adm,H),(14-358,Et,D-34,O,S,O,1-Adm,H),(14-359,Et,D-35,O,S,O,1-Adm,H),(14-360,Et,D-36,O,S,O,1-Adm,H),(14-361,Et,D-1,O,S,O,2-Adm,H),(14-362,Et,D-2,O,S,O,2-Adm,H),(14-363,Et,D-3,O,S,O,2-Adm,H),(14-364,Et,D-4,O,S,O,2-Adm,H),(14-365,Et,D-5,O,S,O,2-Adm,H),(14-366,Et,D-6,O,S,O,2-Adm,H),(14-367,Et,D-7,O,S,O,2-Adm,H),(14-368,Et,D-8,O,S,O,2-Adm,H),(14-369,Et,D-9,O,S,O,2-Adm,H),(14-370,Et,D-10,O,S,O,2-Adm,H),(14-371,Et,D-11,O,S,O,2-Adm,H),(14-372,Et,D-12,O,S,O,2-Adm,H),(14-373,Et,D-13,O,S,O,2-Adm,H),(14-374,Et,D-14,O,S,O,2-Adm,H),(14-375,Et,D-15,O,S,O,2-Adm,H),(14-376,Et,D-16,O,S,O,2-Adm,H),(14-377,Et,D-17,O,S,O,2-Adm,H),(14-378,Et,D-18,O,S,O,2-Adm,H),(14-379,Et,D-19,O,S,O,2-Adm,H),(14-380,Et,D-20,O,S,O,2-Adm,H),(14-381,Et,D-21,O,S,O,2-Adm,H),(14-382,Et,D-22,O,S,O,2-Adm,H),(14-383,Et,D-23,O,S,O,2-Adm,H),(14-384,Et,D-24,O,S,O,2-Adm,H),(14-385,Et,D-25,O,S,O,2-Adm,H),(14-386,Et,D-26,O,S,O,2-Adm,H),(14-387,Et,D-27,O,S,O,2-Adm,H),(14-388,Et,D-28,O,S,O,2-Adm,H),(14-389,Et,D-29,O,S,O,2-Adm,H),(14-390,Et,D-30,O,S,O,2-Adm,H),(14-391,Et,D-31,O,S,O,2-Adm,H),(14-392,Et,D-32,O,S,O,2-Adm,H),(14-393,Et,D-33,O,S,O,2-Adm,H),(14-394,Et,D-34,O,S,O,2-Adm,H),(14-395,Et,D-35,O,S,O,2-Adm,H),(14-396,Et,D-36,O,S,O,2-Adm,H),(14-397,Et,D-1,O,S,O,5-OH-2-Adm,H),(14-398,Et,D-2,O,S,O,5-OH-2-Adm,H),(14-399,Et,D-3,O,S,O,5-OH-2-Adm,H),(14-400,Et,D-4,O,S,O,5-OH-2-Adm,H),(14-401,Et,D-5,O,S,O,5-OH-2-Adm,H),(14-402,Et,D-6,O,S,O,5-OH-2-Adm,H),(14-403,Et,D-7,O,S,O,5-OH-2-Adm,H),(14-404,Et,D-8,O,S,O,5-OH-2-Adm,H),(14-405,Et,D-9,O,S,O,5-OH-2-Adm,H),(14-406,Et,D-10,O,S,O,5-OH-2-Adm,H),(14-407,Et,D-11,O,S,O,5-OH-2-Adm,H),(14-408,Et,D-12,O,S,O,5-OH-2-Adm,H),(14-409,Et,D-13,O,S,O,5-OH-2-Adm,H),(14-410,Et,D-14,O,S,O,5-OH-2-Adm,H),(14-411,Et,D-15,O,S,O,5-OH-2-Adm,H),(14-412,Et,D-16,O,S,O,5-OH-2-Adm,H),(14-413,Et,D-17,O,S,O,5-OH-2-Adm,H),(14-414,Et,D-18,O,S,O,5-OH-2-Adm,H),(14-415,Et,D-19,O,S,O,5-OH-2-Adm,H),(14-416,Et,D-20,O,S,O,5-OH-2-Adm,H),(14-417,Et,D-21,O,S,O,5-OH-2-Adm,H),(14-418,Et,D-22,O,S,O,5-OH-2-Adm,H),(14-419,Et,D-23,O,S,O,5-OH-2-Adm,H),(14-420,Et,D-24,O,S,O,5-OH-2-Adm,H),(14-421,Et,D-25,O,S,O,5-OH-2-Adm,H),(14-422,Et,D-26,O,S,O,5-OH-2-Adm,H),(14-423,Et,D-27,O,S,O,5-OH-2-Adm,H),(14-424,Et,D-28,O,S,O,5-OH-2-Adm,H),(14-425,Et,D-29,O,S,O,5-OH-2-Adm,H),(14-426,Et,D-30,O,S,O,5-OH-2-Adm,H),(14-427,Et,D-31,O,S,O,5-OH-2-Adm,H),(14-428,Et,D-32,O,S,O,5-OH-2-Adm,H),(14-429,Et,D-33,O,S,O,5-OH-2-Adm,H),(14-430,Et,D-34,O,S,O,5-OH-2-Adm,H),(14-431,Et,D-35,O,S,O,5-OH-2-Adm,H),(14-432,Et,D-36,O,S,O,5-OH-2-Adm,H),(14-433,Et,E-1,O,S,O,1-Adm,H),(14-434,Et,E-2,O,S,O,1-Adm,H),(14-435,Et,E-3,O,S,O,1-Adm,H),(14-436,Et,E-4,O,S,O,1-Adm,H),(14-437,Et,E-5,O,S,O,1-Adm,H),(14-438,Et,E-6,O,S,O,1-Adm,H),(14-439,Et,E-7,O,S,O,1-Adm,H),(14-440,Et,E-8,O,S,O,1-Adm,H),(14-441,Et,E-9,O,S,O,1-Adm,H),(14-442,Et,E-10,O,S,O,1-Adm,H),(14-443,Et,E-11,O,S,O,1-Adm,H),(14-444,Et,E-12,O,S,O,1-Adm,H),(14-445,Et,E-13,O,S,O,1-Adm,H),(14-446,Et,E-14,O,S,O,1-Adm,H),(14-447,Et,E-15,O,S,O,1-Adm,H),(14-448,Et,E-16,O,S,O,1-Adm,H),(14-449,Et,E-17,O,S,O,1-Adm,H),(14-450,Et,E-18,O,S,O,1-Adm,H),(14-451,Et,E-19,O,S,O,1-Adm,H),(14-452,Et,E-20,O,S,O,1-Adm,H),(14-453,Et,E-21,O,S,O,1-Adm,H),(14-454,Et,E-22,O,S,O,1-Adm,H),(14-455,Et,E-23,O,S,O,1-Adm,H),(14-456,Et,E-24,O,S,O,1-Adm,H),(14-457,Et,E-25,O,S,O,1-Adm,H),(14-458,Et,E-26,O,S,O,1-Adm,H),(14-459,Et,E-27,O,S,O,1-Adm,H),(14-460,Et,E-28,O,S,O,1-Adm,H),(14-461,Et,E-29,O,S,O,1-Adm,H),(14-462,Et,E-30,O,S,O,1-Adm,H),(14-463,Et,E-31,O,S,O,1-Adm,H),(14-464,Et,E-32,O,S,O,1-Adm,H),(14-465,Et,E-33,O,S,O,1-Adm,H),(14-466,Et,E-34,O,S,O,1-Adm,H),(14-467,Et,E-35,O,S,O,1-Adm,H),(14-468,Et,E-36,O,S,O,1-Adm,H),(14-469,Et,E-1,O,S,O,2-Adm,H),(14-470,Et,E-2,O,S,O,2-Adm,H),(14-471,Et,E-3,O,S,O,2-Adm,H),(14-472,Et,E-4,O,S,O,2-Adm,H),(14-473,Et,E-5,O,S,O,2-Adm,H),(14-474,Et,E-6,O,S,O,2-Adm,H),(14-475,Et,E-7,O,S,O,2-Adm,H),(14-476,Et,E-8,O,S,O,2-Adm,H),(14-477,Et,E-9,O,S,O,2-Adm,H),(14-478,Et,E-10,O,S,O,2-Adm,H),(14-479,Et,E-11,O,S,O,2-Adm,H),(14-480,Et,E-12,O,S,O,2-Adm,H),(14-481,Et,E-13,O,S,O,2-Adm,H),(14-482,Et,E-14,O,S,O,2-Adm,H),(14-483,Et,E-15,O,S,O,2-Adm,H),(14-484,Et,E-16,O,S,O,2-Adm,H),(14-485,Et,E-17,O,S,O,2-Adm,H),(14-486,Et,E-18,O,S,O,2-Adm,H),(14-487,Et,E-19,O,S,O,2-Adm,H),(14-488,Et,E-20,O,S,O,2-Adm,H),(14-489,Et,E-21,O,S,O,2-Adm,H),(14-490,Et,E-22,O,S,O,2-Adm,H),(14-491,Et,E-23,O,S,O,2-Adm,H),(14-492,Et,E-24,O,S,O,2-Adm,H),(14-493,Et,E-25,O,S,O,2-Adm,H),(14-494,Et,E-26,O,S,O,2-Adm,H),(14-495,Et,E-27,O,S,O,2-Adm,H),(14-496,Et,E-28,O,S,O,2-Adm,H),(14-497,Et,E-29,O,S,O,2-Adm,H),(14-498,Et,E-30,O,S,O,2-Adm,H),(14-499,Et,E-31,O,S,O,2-Adm,H),(14-500,Et,E-32,O,S,O,2-Adm,H),(14-501,Et,E-33,O,S,O,2-Adm,H),(14-502,Et,E-34,O,S,O,2-Adm,H),(14-503,Et,E-35,O,S,O,2-Adm,H),(14-504,Et,E-36,O,S,O,2-Adm,H),(14-505,Et,E-1,O,S,O,5-OH-2-Adm,H),(14-506,Et,E-2,O,S,O,5-OH-2-Adm,H),(14-507,Et,E-3,O,S,O,5-OH-2-Adm,H),(14-508,Et,E-4,O,S,O,5-OH-2-Adm,H),(14-509,Et,E-5,O,S,O,5-OH-2-Adm,H),(14-510,Et,E-6,O,S,O,5-OH-2-Adm,H),(14-511,Et,E-7,O,S,O,5-OH-2-Adm,H),(14-512,Et,E-8,O,S,O,5-OH-2-Adm,H),(14-513,Et,E-9,O,S,O,5-OH-2-Adm,H),(14-514,Et,E-10,O,S,O,5-OH-2-Adm,H),(14-515,Et,E-11,O,S,O,5-OH-2-Adm,H),(14-516,Et,E-12,O,S,O,5-OH-2-Adm,H),(14-517,Et,E-13,O,S,O,5-OH-2-Adm,H),(14-518,Et,E-14,O,S,O,5-OH-2-Adm,H),(14-519,Et,E-15,O,S,O,5-OH-2-Adm,H),(14-520,Et,E-16,O,S,O,5-OH-2-Adm,H),(14-521,Et,E-17,O,S,O,5-OH-2-Adm,H),(14-522,Et,E-18,O,S,O,5-OH-2-Adm,H),(14-523,Et,E-19,O,S,O,5-OH-2-Adm,H),(14-524,Et,E-20,O,S,O,5-OH-2-Adm,H),(14-525,Et,E-21,O,S,O,5-OH-2-Adm,H),(14-526,Et,E-22,O,S,O,5-OH-2-Adm,H),(14-527,Et,E-23,O,S,O,5-OH-2-Adm,H),(14-528,Et,E-24,O,S,O,5-OH-2-Adm,H),(14-529,Et,E-25,O,S,O,5-OH-2-Adm,H),(14-530,Et,E-26,O,S,O,5-OH-2-Adm,H),(14-531,Et,E-27,O,S,O,5-OH-2-Adm,H),(14-532,Et,E-28,O,S,O,5-OH-2-Adm,H),(14-533,Et,E-29,O,S,O,5-OH-2-Adm,H),(14-534,Et,E-30,O,S,O,5-OH-2-Adm,H),(14-535,Et,E-31,O,S,O,5-OH-2-Adm,H),(14-536,Et,E-32,O,S,O,5-OH-2-Adm,H),(14-537,Et,E-33,O,S,O,5-OH-2-Adm,H),(14-538,Et,E-34,O,S,O,5-OH-2-Adm,H),(14-539,Et,E-35,O,S,O,5-OH-2-Adm,H),(14-540,Et,E-36,O,S,O,5-OH-2-Adm,H),(14-541,Et,F-1,O,S,O,1-Adm,H),(14-542,Et,F-2,O,S,O,1-Adm,H),(14-543,Et,F-3,O,S,O,1-Adm,H),(14-544,Et,F-4,O,S,O,1-Adm,H),(14-545,Et,F-5,O,S,O,1-Adm,H),(14-546,Et,F-6,O,S,O,1-Adm,H),(14-547,Et,F-7,O,S,O,1-Adm,H),(14-548,Et,F-8,O,S,O,1-Adm,H),(14-549,Et,F-9,O,S,O,1-Adm,H),(14-550,Et,F-10,O,S,O,1-Adm,H),(14-551,Et,F-11,O,S,O,1-Adm,H),(14-552,Et,F-12,O,S,O,1-Adm,H),(14-553,Et,F-13,O,S,O,1-Adm,H),(14-554,Et,F-14,O,S,O,1-Adm,H),(14-555,Et,F-15,O,S,O,1-Adm,H),(14-556,Et,F-16,O,S,O,1-Adm,H),(14-557,Et,F-17,O,S,O,1-Adm,H),(14-558,Et,F-18,O,S,O,1-Adm,H),(14-559,Et,F-19,O,S,O,1-Adm,H),(14-560,Et,F-20,O,S,O,1-Adm,H),(14-561,Et,F-21,O,S,O,1-Adm,H),(14-562,Et,F-22,O,S,O,1-Adm,H),(14-563,Et,F-23,O,S,O,1-Adm,H),(14-564,Et,F-24,O,S,O,1-Adm,H),(14-565,Et,F-25,O,S,O,1-Adm,H),(14-566,Et,F-26,O,S,O,1-Adm,H),(14-567,Et,F-27,O,S,O,1-Adm,H),(14-568,Et,F-28,O,S,O,1-Adm,H),(14-569,Et,F-29,O,S,O,1-Adm,H),(14-570,Et,F-30,O,S,O,1-Adm,H),(14-571,Et,F-31,O,S,O,1-Adm,H),(14-572,Et,F-32,O,S,O,1-Adm,H),(14-573,Et,F-33,O,S,O,1-Adm,H),(14-574,Et,F-34,O,S,O,1-Adm,H),(14-575,Et,F-35,O,S,O,1-Adm,H),(14-576,Et,F-36,O,S,O,1-Adm,H),(14-577,Et,F-1,O,S,O,2-Adm,H),(14-578,Et,F-2,O,S,O,2-Adm,H),(14-579,Et,F-3,O,S,O,2-Adm,H),(14-580,Et,F-4,O,S,O,2-Adm,H),(14-581,Et,F-5,O,S,O,2-Adm,H),(14-582,Et,F-6,O,S,O,2-Adm,H),(14-583,Et,F-7,O,S,O,2-Adm,H),(14-584,Et,F-8,O,S,O,2-Adm,H),(14-585,Et,F-9,O,S,O,2-Adm,H),(14-586,Et,F-10,O,S,O,2-Adm,H),(14-587,Et,F-11,O,S,O,2-Adm,H),(14-588,Et,F-12,O,S,O,2-Adm,H),(14-589,Et,F-13,O,S,O,2-Adm,H),(14-590,Et,F-14,O,S,O,2-Adm,H),(14-591,Et,F-15,O,S,O,2-Adm,H),(14-592,Et,F-16,O,S,O,2-Adm,H),(14-593,Et,F-17,O,S,O,2-Adm,H),(14-594,Et,F-18,O,S,O,2-Adm,H),(14-595,Et,F-19,O,S,O,2-Adm,H),(14-596,Et,F-20,O,S,O,2-Adm,H),(14-597,Et,F-21,O,S,O,2-Adm,H),(14-598,Et,F-22,O,S,O,2-Adm,H),(14-599,Et,F-23,O,S,O,2-Adm,H),(14-600,Et,F-24,O,S,O,2-Adm,H),(14-601,Et,F-25,O,S,O,2-Adm,H),(14-602,Et,F-26,O,S,O,2-Adm,H),(14-603,Et,F-27,O,S,O,2-Adm,H),(14-604,Et,F-28,O,S,O,2-Adm,H),(14-605,Et,F-29,O,S,O,2-Adm,H),(14-606,Et,F-30,O,S,O,2-Adm,H),(14-607,Et,F-31,O,S,O,2-Adm,H),(14-608,Et,F-32,O,S,O,2-Adm,H),(14-609,Et,F-33,O,S,O,2-Adm,H),(14-610,Et,F-34,O,S,O,2-Adm,H),(14-611,Et,F-35,O,S,O,2-Adm,H),(14-612,Et,F-36,O,S,O,2-Adm,H),(14-613,Et,F-1,O,S,O,5-OH-2-Adm,H),(14-614,Et,F-2,O,S,O,5-OH-2-Adm,H),(14-615,Et,F-3,O,S,O,5-OH-2-Adm,H),(14-616,Et,F-4,O,S,O,5-OH-2-Adm,H),(14-617,Et,F-5,O,S,O,5-OH-2-Adm,H),(14-618,Et,F-6,O,S,O,5-OH-2-Adm,H),(14-619,Et,F-7,O,S,O,5-OH-2-Adm,H),(14-620,Et,F-8,O,S,O,5-OH-2-Adm,H),(14-621,Et,F-9,O,S,O,5-OH-2-Adm,H),(14-622,Et,F-10,O,S,O,5-OH-2-Adm,H),(14-623,Et,F-11,O,S,O,5-OH-2-Adm,H),(14-624,Et,F-12,O,S,O,5-OH-2-Adm,H),(14-625,Et,F-13,O,S,O,5-OH-2-Adm,H),(14-626,Et,F-14,O,S,O,5-OH-2-Adm,H),(14-627,Et,F-15,O,S,O,5-OH-2-Adm,H),(14-628,Et,F-16,O,S,O,5-OH-2-Adm,H),(14-629,Et,F-17,O,S,O,5-OH-2-Adm,H),(14-630,Et,F-18,O,S,O,5-OH-2-Adm,H),(14-631,Et,F-19,O,S,O,5-OH-2-Adm,H),(14-632,Et,F-20,O,S,O,5-OH-2-Adm,H),(14-633,Et,F-21,O,S,O,5-OH-2-Adm,H),(14-634,Et,F-22,O,S,O,5-OH-2-Adm,H),(14-635,Et,F-23,O,S,O,5-OH-2-Adm,H),(14-636,Et,F-24,O,S,O,5-OH-2-Adm,H),(14-637,Et,F-25,O,S,O,5-OH-2-Adm,H),(14-638,Et,F-26,O,S,O,5-OH-2-Adm,H),(14-639,Et,F-27,O,S,O,5-OH-2-Adm,H),(14-640,Et,F-28,O,S,O,5-OH-2-Adm,H),(14-641,Et,F-29,O,S,O,5-OH-2-Adm,H),(14-642,Et,F-30,O,S,O,5-OH-2-Adm,H),(14-643,Et,F-31,O,S,O,5-OH-2-Adm,H),(14-644,Et,F-32,O,S,O,5-OH-2-Adm,H),(14-645,Et,F-33,O,S,O,5-OH-2-Adm,H),(14-646,Et,F-34,O,S,O,5-OH-2-Adm,H),(14-647,Et,F-35,O,S,O,5-OH-2-Adm,H),(14-648,Et,F-36,O,S,O,5-OH-2-Adm,H),(14-649,Et,G-1,O,S,O,1-Adm,H),(14-650,Et,G-2,O,S,O,1-Adm,H),(14-651,Et,G-3,O,S,O,1-Adm,H),(14-652,Et,G-4,O,S,O,1-Adm,H),(14-653,Et,G-5,O,S,O,1-Adm,H),(14-654,Et,G-6,O,S,O,1-Adm,H),(14-655,Et,G-7,O,S,O,1-Adm,H),(14-656,Et,G-8,O,S,O,1-Adm,H),(14-657,Et,G-9,O,S,O,1-Adm,H),(14-658,Et,G-1,O,S,O,2-Adm,H),(14-659,Et,G-2,O,S,O,2-Adm,H),(14-660,Et,G-3,O,S,O,2-Adm,H),(14-661,Et,G-4,O,S,O,2-Adm,H),(14-662,Et,G-5,O,S,O,2-Adm,H),(14-663,Et,G-6,O,S,O,2-Adm,H),(14-664,Et,G-7,O,S,O,2-Adm,H),(14-665,Et,G-8,O,S,O,2-Adm,H),(14-666,Et,G-9,O,S,O,2-Adm,H),(14-667,Et,G-1,O,S,O,5-OH-2-Adm,H),(14-668,Et,G-2,O,S,O,5-OH-2-Adm,H),(14-669,Et,G-3,O,S,O,5-OH-2-Adm,H),(14-670,Et,G-4,O,S,O,5-OH-2-Adm,H),(14-671,Et,G-5,O,S,O,5-OH-2-Adm,H),(14-672,Et,G-6,O,S,O,5-OH-2-Adm,H),(14-673,Et,G-7,O,S,O,5-OH-2-Adm,H),(14-674,Et,G-8,O,S,O,5-OH-2-Adm,H),(14-675,Et,G-9,O,S,O,5-OH-2-Adm,H),(14-676,Et,H-1,O,S,O,1-Adm,H),(14-677,Et,H-2,O,S,O,1-Adm,H),(14-678,Et,H-3,O,S,O,1-Adm,H),(14-679,Et,H-4,O,S,O,1-Adm,H),(14-680,Et,H-5,O,S,O,1-Adm,H),(14-681,Et,H-6,O,S,O,1-Adm,H),(14-682,Et,H-7,O,S,O,1-Adm,H),(14-683,Et,H-8,O,S,O,1-Adm,H),(14-684,Et,H-9,O,S,O,1-Adm,H),(14-685,Et,H-1,O,S,O,2-Adm,H),(14-686,Et,H-2,O,S,O,2-Adm,H),(14-687,Et,H-3,O,S,O,2-Adm,H),(14-688,Et,H-4,O,S,O,2-Adm,H),(14-689,Et,H-5,O,S,O,2-Adm,H),(14-690,Et,H-6,O,S,O,2-Adm,H),(14-691,Et,H-7,O,S,O,2-Adm,H),(14-692,Et,H-8,O,S,O,2-Adm,H),(14-693,Et,H-9,O,S,O,2-Adm,H),(14-694,Et,H-1,O,S,O,5-OH-2-Adm,H),(14-695,Et,H-2,O,S,O,5-OH-2-Adm,H),(14-696,Et,H-3,O,S,O,5-OH-2-Adm,H),(14-697,Et,H-4,O,S,O,5-OH-2-Adm,H),(14-698,Et,H-5,O,S,O,5-OH-2-Adm,H),(14-699,Et,H-6,O,S,O,5-OH-2-Adm,H),(14-700,Et,H-7,O,S,O,5-OH-2-Adm,H),(14-701,Et,H-8,O,S,O,5-OH-2-Adm,H),(14-702,Et,H-9,O,S,O,5-OH-2-Adm,H),(14-703,Et,I-1,O,S,O,1-Adm,H),(14-704,Et,I-2,O,S,O,1-Adm,H),(14-705,Et,I-3,O,S,O,1-Adm,H),(14-706,Et,I-4,O,S,O,1-Adm,H),(14-707,Et,I-5,O,S,O,1-Adm,H),(14-708,Et,I-6,O,S,O,1-Adm,H),(14-709,Et,I-7,O,S,O,1-Adm,H),(14-710,Et,I-8,O,S,O,1-Adm,H),(14-711,Et,I-9,O,S,O,1-Adm,H),(14-712,Et,I-1,O,S,O,2-Adm,H),(14-713,Et,I-2,O,S,O,2-Adm,H),(14-714,Et,I-3,O,S,O,2-Adm,H),(14-715,Et,I-4,O,S,O,2-Adm,H),(14-716,Et,I-5,O,S,O,2-Adm,H),(14-717,Et,I-6,O,S,O,2-Adm,H),(14-718,Et,I-7,O,S,O,2-Adm,H),(14-719,Et,I-8,O,S,O,2-Adm,H),(14-720,Et,I-9,O,S,O,2-Adm,H),(14-721,Et,I-1,O,S,O,5-OH-2-Adm,H),(14-722,Et,I-2,O,S,O,5-OH-2-Adm,H),(14-723,Et,I-3,O,S,O,5-OH-2-Adm,H),(14-724,Et,I-4,O,S,O,5-OH-2-Adm,H),(14-725,Et,I-5,O,S,O,5-OH-2-Adm,H),(14-726,Et,I-6,O,S,O,5-OH-2-Adm,H),(14-727,Et,I-7,O,S,O,5-OH-2-Adm,H),(14-728,Et,I-8,O,S,O,5-OH-2-Adm,H),(14-729,Et,I-9,O,S,O,5-OH-2-Adm,H),(14-730,Et,J-1,O,S,O,1-Adm,H),(14-731,Et,J-2,O,S,O,1-Adm,H),(14-732,Et,J-3,O,S,O,1-Adm,H),(14-733,Et,J-4,O,S,O,1-Adm,H),(14-734,Et,J-5,O,S,O,1-Adm,H),(14-735,Et,J-6,O,S,O,1-Adm,H),(14-736,Et,J-7,O,S,O,1-Adm,H),(14-737,Et,J-8,O,S,O,1-Adm,H),(14-738,Et,J-9,O,S,O,1-Adm,H),(14-739,Et,J-1,O,S,O,2-Adm,H),(14-740,Et,J-2,O,S,O,2-Adm,H),(14-741,Et,J-3,O,S,O,2-Adm,H),(14-742,Et,J-4,O,S,O,2-Adm,H),(14-743,Et,J-5,O,S,O,2-Adm,H),(14-744,Et,J-6,O,S,O,2-Adm,H),(14-745,Et,J-7,O,S,O,2-Adm,H),(14-746,Et,J-8,O,S,O,2-Adm,H),(14-747,Et,J-9,O,S,O,2-Adm,H),(14-748,Et,J-1,O,S,O,5-OH-2-Adm,H),(14-749,Et,J-2,O,S,O,5-OH-2-Adm,H),(14-750,Et,J-3,O,S,O,5-OH-2-Adm,H),(14-751,Et,J-4,O,S,O,5-OH-2-Adm,H),(14-752,Et,J-5,O,S,O,5-OH-2-Adm,H),(14-753,Et,J-6,O,S,O,5-OH-2-Adm,H),(14-754,Et,J-7,O,S,O,5-OH-2-Adm,H),(14-755,Et,J-8,O,S,O,5-OH-2-Adm,H),(14-756,Et,J-9,O,S,O,5-OH-2-Adm,H),(14-757,Et,K-1,O,S,O,1-Adm,H),(14-758,Et,K-2,O,S,O,1-Adm,H),(14-759,Et,K-3,O,S,O,1-Adm,H),(14-760,Et,K-4,O,S,O,1-Adm,H),(14-761,Et,K-5,O,S,O,1-Adm,H),(14-762,Et,K-6,O,S,O,1-Adm,H),(14-763,Et,K-7,O,S,O,1-Adm,H),(14-764,Et,K-8,O,S,O,1-Adm,H),(14-765,Et,K-9,O,S,O,1-Adm,H),(14-766,Et,K-1,O,S,O,2-Adm,H),(14-767,Et,K-2,O,S,O,2-Adm,H),(14-768,Et,K-3,O,S,O,2-Adm,H),(14-769,Et,K-4,O,S,O,2-Adm,H),(14-770,Et,K-5,O,S,O,2-Adm,H),(14-771,Et,K-6,O,S,O,2-Adm,H),(14-772,Et,K-7,O,S,O,2-Adm,H),(14-773,Et,K-8,O,S,O,2-Adm,H),(14-774,Et,K-9,O,S,O,2-Adm,H),(14-775,Et,K-1,O,S,O,5-OH-2-Adm,H),(14-776,Et,K-2,O,S,O,5-OH-2-Adm,H),(14-777,Et,K-3,O,S,O,5-OH-2-Adm,H),(14-778,Et,K-4,O,S,O,5-OH-2-Adm,H),(14-779,Et,K-5,O,S,O,5-OH-2-Adm,H),(14-780,Et,K-6,O,S,O,5-OH-2-Adm,H),(14-781,Et,K-7,O,S,O,5-OH-2-Adm,H),(14-782,Et,K-8,O,S,O,5-OH-2-Adm,H),(14-783,Et,K-9,O,S,O,5-OH-2-Adm,H)

EXPERIMENTAL EXAMPLE 1 Evaluation of 11β-HSD1 Inhibitors (EnzymeActivity Assay on Human 11β-HSD1)

Enzymatic activity for human 11β-HSD1 was determined in a 10 μl finalvolume of assay mixture containing 50 mM sodium phosphate buffer (pH7.6), 1 mg/ml bovine serum albumin, 0.42 mg/ml NADPH, 1.26 mg/mlglucose-6-phosphate, glucose-6-phosphate dehydrogenase, test compound,recombinant human 11β-HSD1, and 5 μM cortisone as substrate. Thereaction was started with the addition of cortisone. After incubationfor 2 hours at 37° C., 5 μl of europium cryptate-labelled anti-cortisolantibody and 5 μl of XL665-labeled cortisol were added. After furtherincubation for 2 hours at room temperature, the homogeneoustime-resolved fluorescence (HTRF) signal was measured. The cortisolproduction was quantitated by a standard curve generated with severalknown concentrations of cortisol in each assay.

The amount of cortisol production without compounds was served ascontrol, and the percent inhibition by test compound at eachconcentration was calculated. The IC50 value of the compound for11β-HSD1 was obtained using the inhibition curve generated by plottingthe percent inhibition versus the concentration of test compound.

EXPERIMENTAL EXAMPLE 2 Evaluation of 11β-HSD1 Inhibitors (EnzymeActivity Assay on Mouse 11β-HSD1)

Enzymatic activity for mouse 11β-HSD1 activity was determined in a 10 μlfinal volume of assay mixture containing 50 mM sodium phosphate buffer(pH 7.6), 1 mg/ml bovine serum albumin, 0.42 mg/ml NADPH, 1.26 mg/mlglucose-6-phosphate, glucose-6-phosphate dehydrogenase, test compound,recombinant mouse 11β-HSD1, and 2 μM 11-dehydrocorticosterone assubstrate. The reaction was started with the addition of11-dehydrocorticosterone. After incubation for 2 hours at 37° C., 5 μlof europium cryptate-labelled anti-cortisol antibody and 5 μl ofXL665-labeled cortisol were added. After further incubation for 2 hoursat room temperature, the HTRF signal was measured. The corticosteroneproduction was quantitated by a standard curve generated with severalknown concentrations of corticosterone in each assay.

The amount of cortisol production without compounds was served ascontrol, and the percent inhibition by compound at each concentrationwas calculated. The IC50 value of the compound for 11β-HSD1 was obtainedusing the inhibition curve generated by plotting the percent inhibitionversus the concentration of test compound.

The results of experimental example 1 and 2 are shown in the followingtable.

TABLE 29 No. humanIC₅₀ (μM) mouseIC₅₀ (μM)  9c 0.18 0.5  12b 0.14 1.6 24b 0.82 0.17 29 0.043 0.33 27 0.26 0.038 II-18  0.035 0.049 II-25 0.051 0.16 II-49  0.071 0.023 II-72  0.077 0.0065 II-117 0.095 0.021II-130 0.086 0.033 II-150 0.010 0.027 II-153 0.025 0.014

EXPERIMENTAL EXAMPLE 3 Materials and Methods in Oral Absorption of11β-HSD1 Inhibitor (1) Animals

Male C57BL/6J Jcl mice were purchased from CLEA Japan at the age of 6weeks. After 1-week preliminary rearing, the mice were used for thisstudy at the age of 7 weeks

(2) Rearing Conditions

The mice were placed at an animal room, where was set at roomtemperature of 23±2° C. and humidity of 55±10%, and lighting cycle timewas 12 hours [light (8:00-20:00)/dark (20:00-8:00)]. The mice wereallowed free access to solid laboratory food (CE-2, CLEA Japan) andsterile tap water through the preliminary rearing and experimentalperiods.

(3) Identification of Animals and Cages

The mice were identified by tail marking with an oil marker pen. Labelsidentifying the study director, purchased date, strain, sex and supplierwere placed on each cage. The mice were housed by 20 mice/cage in thepreliminary rearing period, and 3 mice/cage in the experimental period.

(4) Group Composition

Oral administration: 20 mg/kg (n=3)

Intravenous administration: 5 mg/kg (n=3)

(5) Preparation of Dosing Formulation Dosing suspension for oraladministration was prepared using 0.5% methyl cellulose (1500 cP)aqueous solution. Dosing solution for intravenous administration wasprepared using N-dimethylacetamide/polyethyleneglycol 400 (½).

(6) Dosing Method

As to oral administration, the dosing suspension at 10 mL/kg wasadministered into the stomach using a feeding tube. As to intravenousadministration, the dosing solution at 2.5 mL/kg was administered intothe caudal vein using a glass syringe.

(7) Evaluation Items

The blood samples were collected from the heart at each sampling point.The drug concentration in plasma was measured using HPLC or LC/MS/MS.

(8) Statistical Analysis

The area under the plasma concentration-time curve (AUC) was calculatedby WinNonlin®, and the bioavailability was calculated by the AUC valuesafter oral and intravenous administration.

FORMULATION EXAMPLES

The following formulation examples 1 to 8 are provided to furtherillustrate the present invention and are not intended to limit the scopeof the present invention. The term of “active ingredient” means acompound of the present invention, a pharmaceutical acceptable salt, ora hydrate thereof.

Formulation Example 1

Hard gelatin capsules are prepared with the following ingredients:

Dose (mg/capsule) Active ingredient 250 Starch (dried) 200 Magnesiumstearate 10 Total 460 mg

Formulation Example 2

Tablets are prepared with the following ingredients:

Dose (mg/tablet) Active ingredient 250 Cellulose (microcrystal) 400Silicon dioxide, fumed 10 Stearic acid 5 Total 665 mg

The ingredients are blended and compressed to form tablets each weighing665 mg.

Formulation Example 3

An aerosol solution is prepared containing the following ingredients:

Weight Active ingredient 0.25 Ethanol 25.75 Propellant 22(chlorodifluoromethane) 74.00 Total 100.00

The active ingredient is mixed with ethanol and the admixture is addedto a portion of the propellant 22, cooled to −30° C. and transferred toa filling device. Then the required amount is provided in a stainlesssteel container and diluted with the reminder of the propellant. Thevalve units are then attached to the container.

Formulation Example 4

Tablets, each containing 60 mg of active ingredient, are made asfollows.

Active ingredient 60 mg Starch 45 mg Microcrystals cellulose 35 mgPolyvinylpyrrolidone (as 10% solution in  4 mg water) Sodiumcarboxymethyl starch 4.5 mg  Magnesium stearate 0.5 mg  Talc  1 mg Total150 mg 

The active ingredient, starch, and cellulose are passed through a No. 45mesh U.S. sieve, and the mixed thoroughly. The aqueous solutioncontaining polyvinylpyrrolidone is mixed with the obtained powder, andthen the admixture is passed through a No. 14 mesh U.S. sieve. Thegranules so produced are dried at 50° C. and passed through a No. 18mesh U.S. sieve. The sodium carboxymethyl starch, magnesium stearate,and talc, previously passed through No. 60 mesh U.S. sieve, are added tothe granules, mixed, and then compressed on a tablet machine to yieldtablets each weighing 150 mg.

Formulation Example 5

Capsules, each containing 80 mg of active ingredient, are made asfollows:

Active ingredient 80 mg Starch 59 mg Microcrystals cellulose 59 mgMagnesium stearate  2 mg Total 200 mg 

The active ingredient, cellulose, starch, and magnesium stearate areblended, passed through a No. 45 mesh U.S. sieve, and filled into hardgelatin capsules in 200 mg quantities.

Formulation Example 6

Suppositories, each containing 225 mg of active ingredient, are made asfollows:

Active ingredient  225 mg Saturated fatty acid glycerides 2000 mg Total2225 mg

The active ingredient is passed through a No. 60 mesh U.S. sieve andsuspended in the saturated fatty acid glycerides previously melted usingthe minimum heat necessary. The mixture is then poured into asuppository mold of nominal 2 g capacity and allowed to cool.

Formulation Example 7

Suspensions, each containing 50 mg of active ingredient, are made asfollows:

Active ingredient 50 mg Sodium carboxymethyl cellulose 50 mg Syrup 1.25mL Benzoic acid solution 0.10 mL Flavor q.v. Color q.v. Purified waterto total 5 mL

The active ingredient is passed through a No. 45 U.S. sieve, and mixedwith the sodium carboxymethyl cellulose and syrup to form a smoothpaste. The benzoic acid solution and flavor are diluted with a portionof the water, added and stirred. Then sufficient water is added toproduce the required volume.

Formulation Example 8

An intravenous formulation may be prepared as follows:

Active ingredient  100 mg Saturated fatty acid glycerides 1000 mL

The solution of the above ingredients is generally administeredintravenously to a patient at a rate of 1 mL per minute.

INDUSTRIAL APPLICABILITY

As is apparent from the experiment as described above, the compoundsaccording to the invention have an inhibitory activity on11-hydroxysteroid dehydrogenase type 1. Thus, the compounds according tothe invention are useful as pharmaceutical compositions for treatingdiabetes.

1. A compound represented by the formula (I):

a pharmaceutically acceptable salt or a solvate thereof, wherein R¹ is agroup of the formula: —C(═O)NR⁴R⁵, wherein R⁴ and R⁵ are eachindependently, hydrogen, optionally substituted alkyl, optionallysubstituted alkenyl, optionally substituted alkynyl, optionallysubstituted cycloalkyl, optionally substituted cycloalkenyl, optionallysubstituted aryl, optionally substituted heteroaryl or optionallysubstituted heterocycle; or R⁴ and R⁵ taken together with the adjacentnitrogen atom to which they are attached may form an optionallysubstituted ring or a group of the formula: —NR⁶C(═O)R⁷, wherein R⁶ ishydrogen, optionally substituted alkyl, optionally substituted alkenyl,optionally substituted alkynyl, optionally substituted cycloalkyl,optionally substituted cycloalkenyl, optionally substituted aryl,optionally substituted heteroaryl, optionally substituted heterocycle,optionally substituted aralkyl or a group of the formula:—C(═O)R⁸, R⁷and R⁸ are each independently, hydrogen, optionally substituted alkyl,optionally substituted alkenyl, optionally substituted alkynyl,optionally substituted cycloalkyl, optionally substituted cycloalkenyl,optionally substituted aryl, optionally substituted heteroaryl oroptionally substituted heterocycle; or R⁷ and R⁸ taken together with theadjacent carbon atom to which they are attached may form an optionallysubstituted ring, X and Y are each independently, —O— or —S—, Z is abond, —O— or —S—, R² is optionally substituted alkyl, optionallysubstituted alkenyl, optionally substituted alkynyl, optionallysubstituted cycloalkyl, optionally substituted cycloalkenyl, optionallysubstituted aryl, optionally substituted heteroaryl, optionallysubstituted heterocycle, optionally substituted acyl or optionallysubstituted carbamoyl, R³ is optionally substituted alkyl, optionallysubstituted alkenyl, optionally substituted alkynyl, optionallysubstituted cycloalkyl, optionally substituted cycloalkenyl, optionallysubstituted aryl, optionally substituted heteroaryl, optionallysubstituted heterocycle, optionally substituted acyl, optionallysubstituted carbamoyl, optionally substituted thiocarbamoyl, optionallysubstituted amino, optionally substituted sulfamoyl or a group of theformula: —R⁹—C(R¹⁰R¹¹)—R¹²—R¹³, R⁹ is —(CH₂)_(m)—, wherein m is aninteger of 0 to 3, R¹⁰ and R¹¹ are each independently, hydrogen,optionally substituted alkyl or halogen; or R¹⁰ and R¹¹ taken togetherwith the adjacent carbon atom to which they are attached may form anoptionally substituted ring, R¹² is —(CH₂)_(n)—, wherein n is an integerof 0 to 3, R¹³ is hydrogen, hydroxy, carboxy, cyano, optionallysubstituted alkyl, optionally substituted alkenyl, optionallysubstituted alkynyl, optionally substituted cycloalkyl, optionallysubstituted cycloalkenyl, optionally substituted aryl, optionallysubstituted heteroaryl, optionally substituted heterocycle, optionallysubstituted alkoxycarbonyl, optionally substituted aralkylcarbonyl,optionally substituted carbamoyl, optionally substituted thiocarbamoyl,optionally substituted alkylsulfonyl, optionally substitutedarylsulfonyl, optionally substituted sulfamoyl, optionally substitutedamino, optionally substituted carbamoyloxy, optionally substitutedalkoxy, optionally substituted alkylthio, a group of the formula:—C(═O)—NR¹⁴R¹⁵, wherein R¹⁴ and R¹⁵ are each independently, hydrogen,optionally substituted amino, optionally substituted alkyl, optionallysubstituted alkenyl, optionally substituted alkynyl, optionallysubstituted cycloalkyl, optionally substituted cycloalkenyl, optionallysubstituted aryl, optionally substituted heteroaryl, optionallysubstituted heterocycle, optionally substituted alkylsulfonyl,optionally substituted arylsulfonyl, optionally substitutedheteroarylsulfonyl or optionally substituted heterocycle sulfonyl; orR¹⁴ and R¹⁵ taken together with the adjacent nitrogen atom to which theyare attached may form an optionally substituted ring or a group of theformula: —NR¹⁶R¹⁷, wherein R¹⁶ and R¹⁷ are each independently, hydrogen,carboxy, hydroxy, optionally substituted alkyl, optionally substitutedalkenyl, optionally substituted alkynyl, optionally substitutedcycloalkyl, optionally substituted cycloalkenyl, optionally substitutedaryl, optionally substituted heteroaryl, optionally substitutedheterocycle, optionally substituted acyl, optionally substitutedcarbamoyl, optionally substituted thiocarbamoyl, optionally substitutedalkylsulfonyl, optionally substituted arylsulfonyl, optionallysubstituted alkyloxycarbonyl or optionally substituted sulfamoyl; or R¹⁶and R¹⁷ taken together with the adjacent nitrogen atom to which they areattached may form an optionally substituted ring, provided that, when R²encompasses a cyclic group and Y is —S—, then the compound is any one ofcompounds shown as follows,


2. The compound according to claim 1, a pharmaceutically acceptable saltor a solvate thereof wherein the compound of the formula (I):

is a compound of the formula (II) represented below.


3. The compound according to claim 2, a pharmaceutically acceptable saltor a solvate thereof, wherein R¹ is a group of the formula: —C(═O)NR⁴R⁵wherein R⁴ and R⁵ have the same meaning as defined in claim 1, Y is —S—and z is
 0. 4. The compound according to claim 1, a pharmaceuticallyacceptable salt or a solvate thereof, wherein R¹ is a group of theformula; —C(═O)NR⁴R⁵ wherein R⁴ and R⁵ have the same meaning as definedin claim
 1. 5. The compound according to claim 4, a pharmaceuticallyacceptable salt or a solvate thereof, wherein either one of R⁴ and R⁵ isoptionally substituted cycloalkyl.
 6. The compound according to claim 5,a pharmaceutically acceptable salt or a solvate thereof, wherein eitherone of R⁴ and R⁵ is optionally substituted adamantyl.
 7. The compoundaccording to claim 4, a pharmaceutically acceptable salt or a solvatethereof, wherein R¹ is a group of the formula (III):


8. The compound according to a one of claim 1, a pharmaceuticallyacceptable salt or a solvate thereof, wherein R² is optionallysubstituted alkyl, optionally substituted cycloalkyl, optionallysubstituted aryl, optionally substituted heteroaryl or optionallysubstituted heterocycle.
 9. The compound according to claim 8, apharmaceutically acceptable salt or a solvate thereof, wherein R² isoptionally substituted alkyl wherein the substituent of said optionallysubstituted alkyl does not encompass a cyclic group, optionallysubstituted alkenyl wherein the substituent of said optionallysubstituted alkenyl does not encompass a cyclic group, optionallysubstituted alkynyl wherein the substituent of said optionallysubstituted alkynyl does not encompass a cyclic group, optionallysubstituted acyl wherein the substituent of said optionally substitutedacyl does not encompass a cyclic group or optionally substitutedcarbamoyl wherein the substituent of said optionally substitutedcarbamoyl does not encompass a cyclic group.
 10. The compound accordingto claim 9, a pharmaceutically acceptable salt or a solvate thereof,wherein R² is optionally substituted alkyl wherein the substituent ofsaid optionally substituted alkyl does not encompass a cyclic group. 11.The compound according to claim 10, a pharmaceutically acceptable saltor a solvate thereof, wherein R² is branched alkyl.
 12. The compoundaccording to claim 1, a pharmaceutically acceptable salt or a solvatethereof, wherein R³ is a group of the formula: —R⁹—C(R¹⁰R¹¹)—R¹²—R¹³wherein R⁹, R¹⁰, R¹¹, R¹² and R¹³ have the same meaning as defined inclaim
 1. 13. The compound according to claim 12, a pharmaceuticallyacceptable salt or a solvate thereof, wherein R⁹ is —CH₂—.
 14. Thecompound according to claim 12, a pharmaceutically acceptable salt or asolvate thereof, wherein R¹⁰ and R¹¹ are each independently optionallysubstituted alkyl; or R¹⁰ and R¹¹ taken together with the adjacentcarbon atom to which they are attached may form an optionallysubstituted ring.
 15. The compound according to claim 12, apharmaceutically acceptable salt or a solvate thereof, wherein R¹² is—(CH₂)_(n)— wherein n is an integer of 0 to
 1. 16. The compoundaccording to claim 12, a pharmaceutically acceptable salt or a solvatethereof, wherein R¹³ is carboxy, cyano or heterocycle.
 17. The compoundaccording to claim 12, a pharmaceutically acceptable salt or a solvatethereof, wherein R¹³ is a group of the formula: —C(═O)—NR¹⁴R¹⁵, whereinR¹⁴ and R¹⁵ are each independently hydrogen, optionally substitutedalkyl, optionally substituted aryl, optionally substituted cycloalkyl,optionally substituted alkylsulfonyl, optionally substitutedarylsulfonyl, optionally substituted heteroarylsulfonyl, optionallysubstituted heterocycle sulfonyl or optionally substituted heterocycle;or R¹⁴ and R¹⁵ taken together with the adjacent nitrogen atom to whichthey are attached may form an optionally substituted ring.
 18. Thecompound according to claim 12, a pharmaceutically acceptable salt or asolvate thereof, wherein R¹³ is a group of the formula: —NR¹⁶R¹⁷,wherein R¹⁶ and R¹⁷ have the same meaning as defined in claim
 1. 19. Thecompound according to claim 18, a pharmaceutically acceptable salt or asolvate thereof, wherein R¹⁶ is a group of the formula: —C(═O)R′,wherein R′ is optionally substituted alkyl, optionally substitutedalkenyl, optionally substituted cycloalkyl, optionally substituted aryl,optionally substituted amino or optionally substituted alkoxy.
 20. Thecompound according to claim 1, a pharmaceutically acceptable salt or asolvate thereof, wherein X and/or Z is(are) —O—.
 21. The compoundaccording to claim 1, a pharmaceutically acceptable salt or a solvatethereof, wherein Y is —S—.
 22. A pharmaceutical composition whichcomprises the compound according to claim 1, a pharmaceuticallyacceptable salt or a solvate thereof.
 23. The pharmaceutical compositionaccording to claim 22, which has an inhibitory activity on11β-hydroxysteroid dehydrogenase type
 1. 24. The pharmaceuticalcomposition according to claim 22 for treating and/or preventingdiabetes.
 25. A method for treating and/or preventing diabetes,comprising administering the compound of claim 1, a pharmaceuticallyacceptable salt or a solvate thereof.
 26. A use of the compound of claim1, a pharmaceutically acceptable salt or a solvate thereof for themanufacture of a pharmaceutical composition for treating and/orpreventing diabetes.